Bw120 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bw120 (Body weight QTL 120) Rattus norvegicus

Symbol: Bw120
Name: Body weight QTL 120
RGD ID: 61404
Previously known as: Niddm5; Non-insulin dependent diabetes mellitus QTL 5
Trait: body mass   (VT:0001259)    
Measurement Type: body mass index (BMI)   (CMO:0000105)    
LOD Score: 5.1
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81217,464,979 - 46,784,661RGD_MAPPER_PIPELINE
mRatBN7.21212,351,619 - 46,669,029RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01214,419,775 - 52,716,770RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01216,444,048 - 54,450,796RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41212,770,194 - 42,387,195RGDRGSC3.4
RGSC_v3.11212,800,123 - 46,649,226RGD
Cross Type: F2
Strains Crossed: WKY 13M 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw120Rattype 2 diabetes mellitus  IDA 61021 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw120Ratincreased body weight  QTM 61083 RGD 
Bw120Ratincreased circulating glucose level  QTM 61083 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw120Ratbody mass index (BMI)  IDA 61083 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw120Ratcontrol condition  IDA 61083 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw120Ratbody weighing method  IDA 61083 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw120Rat13M  IEA 61083 RGD 
Bw120RatWKY  IEA 61083 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw120Ratbody mass  IDA 61083 RGD 


#
Reference Title
Reference Citation
1. Genetic modifiers of Leprfa associated with variability in insulin production and susceptibility to NIDDM. Chung WK, etal., Genomics 1997 May 1;41(3):332-44
2. Identification of genetic loci involved in diabetes using a rat model of depression. Solberg Woods LC, etal., Mamm Genome. 2009 Aug 22.
3. Mapping and characterization of quantitative trait loci for non-insulin-dependent diabetes mellitus with an improved genetic map in the Otsuka Long-Evans Tokushima fatty rat. Wei S, etal., Mamm Genome 1999 Mar;10(3):249-58

Related QTL Description Reference
Bw88 maps to same region RGD:2312611



1 to 20 of 733 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1560686Sdk1sidekick cell adhesion molecule 1121237807413363934Rat
1564193Ube2c-ps2ubiquitin-conjugating enzyme E2C, pseudogene 2121266888412669423Rat
41240022LOC120096102U6 spliceosomal RNA121303886713038969Rat
1584808Nip7-ps9nucleolar pre-rRNA processing protein NIP7, pseudogene 9121342089613421417Rat
41079527LOC120095893uncharacterized LOC120095893121343303013460245Rat
7598302LOC102547234uncharacterized LOC102547234121354778913607490Rat
2323211Card11caspase recruitment domain family, member 11121362114013758115Rat
71018Gna12G protein subunit alpha 12121380558013886255Rat
1311314Amz1archaelysin family metallopeptidase 1121388651813924275Rat
1565146Brat1BRCA1-associated ATM activator 1121392888913951760Rat
1311349IqceIQ motif containing E121394329013982708Rat
1309549Ttyh3tweety family member 3121399683114025457Rat
620587LfngLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase121403055114038996Rat
71055Grifingalectin-related inter-fiber protein121408017014082892Rat
1308214Chst12carbohydrate sulfotransferase 12121411063114129099Rat
1598146Kif19bkinesin family member 19B121414416314196259Rat
41188349LOC120095895uncharacterized LOC120095895121414908814152690Rat
41182922LOC120096093U6 spliceosomal RNA121416998914170094Rat
1309018Eif3beukaryotic translation initiation factor 3, subunit B121419640314220865Rat
11502171LOC108352425uncharacterized LOC108352425121422308014265458Rat

1 to 20 of 733 rows
1 to 20 of 1062 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
33961D12Mit5133121235161912351752Ratregion
33911D12Mit6139121235161912351758Ratregion
5085758BM390892215121237843112378646Ratregion
5086449BM386455156121237862412378780Ratregion
36221D12Rat4292121238654912386833Ratregion
5037119RH45568265121241281312413078Ratregion
1638964D12Got23111121265868012658791Ratregion
5064774BF405084112121276786512767977Ratregion
5081633BE117712186121280532612805512Ratregion
44951D12Got26220121281017712810397Ratregion
39330D12Rat39231121290184612902077Ratregion
5683878D12Hmgc3194121300829613008490Ratregion
5683880D12Hmgc4170121310437613104548Ratregion
502796544.MMHAP70FRG11.seq189121313121613131405Ratregion
5061402BF396334237121327745513277692Ratregion
5076662RH139306121121335155113351672Ratregion
44952D12Got27156121343671213436870Ratregion
5086695BE115283162121356318313563345Ratregion
44950D12Wox5135121363552313635658Ratregion
7387286rs8164304121374792313747923Ratregion
1 to 20 of 1062 rows

Flank 1: (D12Mit5)
Rat AssemblyChrPosition (strand)Source
GRCr81217,464,979 - 17,465,112 (+)Marker Load Pipeline
mRatBN7.21212,351,619 - 12,351,752 (+)MAPPER
Rnor_6.01214,419,775 - 14,419,907NCBI
Rnor_5.01216,444,048 - 16,444,180UniSTS
RGSC_v3.41212,770,194 - 12,770,327RGD
RGSC_v3.41212,770,195 - 12,770,327UniSTS
RGSC_v3.11212,800,123 - 12,800,255RGD
Celera1214,127,014 - 14,127,146UniSTS
RH 3.4 Map12163.4RGD
RH 3.4 Map12163.4UniSTS
Flank 2: (D12Mgh6)
Rat AssemblyChrPosition (strand)Source
GRCr81246,784,521 - 46,784,661 (+)Marker Load Pipeline
RGSC_v3.41242,387,056 - 42,387,195UniSTS
Celera1242,747,219 - 42,747,358UniSTS
RH 3.4 Map12772.72RGD
RH 2.0 Map12534.5RGD
Cytogenetic Map12 RGD


1 to 10 of 70 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
61443Btemp2Thermal response to stress QTL 23.30.000094body temperature trait (VT:0005535)core body temperature (CMO:0001036)121502518320794014Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122308134044726024Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12931821612829686Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
737822Alc10Alcohol consumption QTL 102.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)121961087040218516Rat

1 to 10 of 70 rows


Database
Acc Id
Source(s)
NCBI Gene Niddm5


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-03-21 Bw120  Body weight QTL 120  Niddm5  Non-insulin dependent diabetes mellitus QTL 5  Name updated 68913 APPROVED
2013-03-21 Bw120  Body weight QTL 120  Niddm5  Non-insulin dependent diabetes mellitus QTL 5  Symbol updated 68687 APPROVED

Note Type Note Reference
qtl_general QTL is also significant for glucose level, (LOD = 3.37) 61083