Mad1l1 (mitotic arrest deficient 1 like 1) - Rat Genome Database

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Gene: Mad1l1 (mitotic arrest deficient 1 like 1) Rattus norvegicus
Analyze
Symbol: Mad1l1
Name: mitotic arrest deficient 1 like 1
RGD ID: 1596881
Description: Predicted to enable identical protein binding activity and kinetochore binding activity. Predicted to be involved in several processes, including attachment of mitotic spindle microtubules to kinetochore; cytoplasmic sequestering of protein; and regulation of mitotic metaphase/anaphase transition. Predicted to act upstream of or within negative regulation of T cell proliferation; regulation of mitotic cell cycle phase transition; and thymus development. Predicted to be located in cytoplasm; nucleus; and spindle pole. Predicted to be part of MAD1 complex; mitotic spindle assembly checkpoint MAD1-MAD2 complex; and nuclear pore nuclear basket. Predicted to be active in kinetochore; mitotic spindle; and nuclear envelope. Predicted to colocalize with mitotic spindle pole. Human ortholog(s) of this gene implicated in lymphoma and prostate cancer. Orthologous to human MAD1L1 (mitotic arrest deficient 1 like 1); PARTICIPATES IN cell cycle pathway, mitotic; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC680006; MAD1 mitotic arrest deficient like 1; MAD1 mitotic arrest deficient-like 1; MAD1 mitotic arrest deficient-like 1 (yeast); mitotic arrest deficient 1-like 1; mitotic spindle assembly checkpoint protein MAD1; similar to Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21214,320,892 - 14,630,750 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1214,320,892 - 14,630,703 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1215,128,699 - 15,439,478 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01215,752,197 - 16,062,988 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01214,778,908 - 15,089,705 (+)NCBIRnor_WKY
Rnor_6.01216,410,083 - 16,721,232 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1216,410,083 - 16,719,824 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01218,402,692 - 18,711,591 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41214,793,899 - 15,107,476 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1216,079,638 - 16,388,296 (+)NCBICelera
Cytogenetic Map12q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-azacytidine  (ISO)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dibutyl phthalate  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
ethyl methanesulfonate  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
ivermectin  (ISO)
melatonin  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
Nor-9-carboxy-delta9-THC  (ISO)
O-methyleugenol  (EXP,ISO)
oxaliplatin  (EXP)
ozone  (ISO)
permethrin  (EXP)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
promethazine  (EXP)
quercetin  (ISO)
sodium arsenite  (ISO)
sodium chromate  (ISO)
sotorasib  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
topotecan  (EXP)
trametinib  (ISO)
triclosan  (ISO)
triptonide  (ISO)
tungsten  (ISO)
valproic acid  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9130602   PMID:11313860   PMID:16189514   PMID:17363900   PMID:17504913   PMID:17938250   PMID:18981471   PMID:20133940   PMID:21558374   PMID:22351768   PMID:22493223   PMID:27107012  


Genomics

Comparative Map Data
Mad1l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21214,320,892 - 14,630,750 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1214,320,892 - 14,630,703 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1215,128,699 - 15,439,478 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01215,752,197 - 16,062,988 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01214,778,908 - 15,089,705 (+)NCBIRnor_WKY
Rnor_6.01216,410,083 - 16,721,232 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1216,410,083 - 16,719,824 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01218,402,692 - 18,711,591 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41214,793,899 - 15,107,476 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1216,079,638 - 16,388,296 (+)NCBICelera
Cytogenetic Map12q11NCBI
MAD1L1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3871,815,795 - 2,232,945 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl71,815,793 - 2,233,243 (-)EnsemblGRCh38hg38GRCh38
GRCh3771,855,431 - 2,272,580 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3671,821,954 - 2,239,109 (-)NCBINCBI36Build 36hg18NCBI36
Build 3471,628,673 - 2,043,593NCBI
Celera71,824,029 - 2,242,272 (-)NCBICelera
Cytogenetic Map7p22.3NCBI
HuRef71,775,090 - 2,191,874 (-)NCBIHuRef
CHM1_171,855,013 - 2,272,150 (-)NCBICHM1_1
T2T-CHM13v2.071,928,871 - 2,346,389 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v271,908,333 - 2,321,257 (-)NCBI
Mad1l1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395139,994,444 - 140,307,346 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5139,994,444 - 140,307,307 (-)EnsemblGRCm39 Ensembl
GRCm385140,008,689 - 140,321,608 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5140,008,689 - 140,321,552 (-)EnsemblGRCm38mm10GRCm38
MGSCv375140,484,643 - 140,797,506 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365140,261,163 - 140,574,024 (-)NCBIMGSCv36mm8
Celera5137,065,976 - 137,380,304 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map578.82NCBI
Mad1l1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554609,340,681 - 9,672,134 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554609,340,728 - 9,672,478 (-)NCBIChiLan1.0ChiLan1.0
MAD1L1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.172,187,104 - 2,604,168 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl72,187,104 - 2,601,328 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v072,070,299 - 2,502,471 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
MAD1L1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1614,889,126 - 15,236,194 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl614,882,875 - 15,236,192 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha616,351,128 - 16,704,460 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0615,015,423 - 15,362,579 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl615,014,693 - 15,362,577 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1614,818,674 - 15,165,656 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0614,745,470 - 15,092,432 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0615,033,169 - 15,380,211 (+)NCBIUU_Cfam_GSD_1.0
Mad1l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344143,053,218 - 143,167,762 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367541,842,588 - 1,957,116 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAD1L1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl31,236,076 - 1,559,041 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.131,236,066 - 1,559,346 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.231,859,406 - 1,883,565 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAD1L1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12819,358,942 - 19,768,079 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2819,359,233 - 19,768,078 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660901,956,015 - 2,370,489 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mad1l1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474027,174,354 - 27,523,492 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474027,174,450 - 27,523,366 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mad1l1
1150 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:130
Count of miRNA genes:100
Interacting mature miRNAs:111
Transcripts:ENSRNOT00000001709
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1600391Edcs2Endometrial carcinoma susceptibility QTL23.50.01uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)12683319017870186Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12844949028302290Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
1300157Rf21Renal function QTL 214.4renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)12931821632103380Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121107382524234895Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382528064557Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
7204484Bp358Blood pressure QTL 3580.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121300829619212979Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121363552330827399Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121363552335682913Rat

Markers in Region
D12Got30  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21214,463,967 - 14,464,125 (+)MAPPERmRatBN7.2
Rnor_6.01216,553,097 - 16,553,251NCBIRnor6.0
Rnor_5.01218,544,968 - 18,545,122UniSTSRnor5.0
RGSC_v3.41214,940,432 - 14,940,590RGDRGSC3.4
RGSC_v3.41214,940,433 - 14,940,590UniSTSRGSC3.4
RGSC_v3.11214,970,361 - 14,970,518RGD
Celera1216,222,308 - 16,222,465UniSTS
RH 3.4 Map12224.9UniSTS
RH 3.4 Map12224.9RGD
RH 2.0 Map12168.7RGD
Cytogenetic Map12q11UniSTS
RH130878  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21214,630,527 - 14,630,680 (+)MAPPERmRatBN7.2
Rnor_6.01216,719,649 - 16,719,801NCBIRnor6.0
Rnor_5.01218,711,416 - 18,711,568UniSTSRnor5.0
RGSC_v3.41215,107,301 - 15,107,453UniSTSRGSC3.4
Celera1216,388,121 - 16,388,273UniSTS
RH 3.4 Map12239.1UniSTS
Cytogenetic Map12q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 18 52 39 19 39 52 23 41 11
Low 1 25 5 2 2 8 11 22 12 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000001709   ⟹   ENSRNOP00000001709
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1214,320,892 - 14,630,703 (+)Ensembl
Rnor_6.0 Ensembl1216,410,083 - 16,719,824 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114435   ⟹   ENSRNOP00000087168
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1214,321,013 - 14,630,703 (+)Ensembl
RefSeq Acc Id: NM_001109387   ⟹   NP_001102857
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21214,320,892 - 14,630,703 (+)NCBI
Rnor_6.01216,410,083 - 16,719,824 (+)NCBI
Rnor_5.01218,402,692 - 18,711,591 (+)NCBI
RGSC_v3.41214,793,899 - 15,107,476 (+)RGD
Celera1216,079,638 - 16,388,296 (+)RGD
Sequence:
RefSeq Acc Id: XM_017598453   ⟹   XP_017453942
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21214,341,507 - 14,630,750 (+)NCBI
Rnor_6.01216,430,280 - 16,721,232 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001102857 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453942 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL89740 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001102857   ⟸   NM_001109387
- UniProtKB: D3ZIV3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453942   ⟸   XM_017598453
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000001709   ⟸   ENSRNOT00000001709
RefSeq Acc Id: ENSRNOP00000087168   ⟸   ENSRNOT00000114435

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZIV3-F1-model_v2 AlphaFold D3ZIV3 1-717 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698458
Promoter ID:EPDNEW_R8983
Type:initiation region
Name:Mad1l1_1
Description:mitotic arrest deficient 1 like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01216,410,086 - 16,410,146EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1596881 AgrOrtholog
BioCyc Gene G2FUF-19910 BioCyc
Ensembl Genes ENSRNOG00000001265 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000001709 ENTREZGENE
  ENSRNOP00000001709.4 UniProtKB/TrEMBL
  ENSRNOP00000087168.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001709 ENTREZGENE
  ENSRNOT00000001709.6 UniProtKB/TrEMBL
  ENSRNOT00000114435.1 UniProtKB/TrEMBL
InterPro MAD UniProtKB/TrEMBL
KEGG Report rno:680006 UniProtKB/TrEMBL
NCBI Gene 680006 ENTREZGENE
PANTHER PTHR23168 UniProtKB/TrEMBL
Pfam MAD UniProtKB/TrEMBL
PhenoGen Mad1l1 PhenoGen
UniProt A0A8I6A596_RAT UniProtKB/TrEMBL
  D3ZIV3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-09-28 Mad1l1  mitotic arrest deficient 1 like 1  Mad1l1  MAD1 mitotic arrest deficient like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-04-20 Mad1l1  MAD1 mitotic arrest deficient like 1  Mad1l1  MAD1 mitotic arrest deficient-like 1 (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Mad1l1  MAD1 mitotic arrest deficient-like 1 (yeast)  Mad1l1  mitotic arrest deficient 1-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-07-08 Mad1l1  mitotic arrest deficient 1-like 1  LOC686419  similar to Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1)  Data Merged 1643240 APPROVED
2008-03-05 Mad1l1  mitotic arrest deficient 1-like 1  LOC680006  similar to Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC680006  similar to Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC686419  similar to Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1)      Symbol and Name status set to provisional 70820 PROVISIONAL