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Gene: Iscu (iron-sulfur cluster assembly enzyme) Rattus norvegicus
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Symbol: Iscu
Name: iron-sulfur cluster assembly enzyme
Description: Predicted to have ferrous iron binding activity; iron-sulfur cluster binding activity; and molecular adaptor activity. Predicted to be involved in cellular iron ion homeostasis. Predicted to localize to the cytosol and mitochondrial matrix. Orthologous to human ISCU (iron-sulfur cluster assembly enzyme); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogenesis pathway; INTERACTS WITH bisphenol A; cyclosporin A; flutamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: iron-sulfur cluster assembly enzyme ISCU, mitochondrial; iron-sulfur cluster scaffold homolog; iron-sulfur cluster scaffold homolog (E. coli); IscU iron-sulfur cluster scaffold homolog; IscU iron-sulfur cluster scaffold homolog (E. coli); LOC288740; RGD1309562; similar to nitrogen fixation cluster-like
Orthologs:
Homo sapiens (human) : ISCU (iron-sulfur cluster assembly enzyme)  HGNC  Alliance
Mus musculus (house mouse) : Iscu (iron-sulfur cluster assembly enzyme)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Iscu (iron-sulfur cluster assembly enzyme)
Pan paniscus (bonobo/pygmy chimpanzee) : ISCU (iron-sulfur cluster assembly enzyme)
Canis lupus familiaris (dog) : ISCU (iron-sulfur cluster assembly enzyme)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Iscu (iron-sulfur cluster assembly enzyme)
Sus scrofa (pig) : ISCU (iron-sulfur cluster assembly enzyme)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01248,621,454 - 48,627,297 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01250,403,338 - 50,409,181 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,886,419 - 43,892,329 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11243,749,819 - 43,755,677 (-)NCBI
Celera1244,453,913 - 44,459,757 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Iscu
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309562
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.