Gene: Spry3 (sprouty RTK signaling antagonist 3) Rattus norvegicus
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Symbol: Spry3
Name: sprouty RTK signaling antagonist 3
Description: Predicted to be involved in negative regulation of MAP kinase activity; negative regulation of Ras protein signal transduction; and negative regulation of fibroblast growth factor receptor signaling pathway. Predicted to localize to the cytosol. Orthologous to human SPRY3 (sprouty RTK signaling antagonist 3); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH bisphenol A; copper atom; copper(0).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC498159; RGD1562172; similar to Sprouty homolog 3 (Spry-3); sprouty homolog 3; sprouty homolog 3 (Drosophila)
Orthologs:
Homo sapiens (human) : SPRY3 (sprouty RTK signaling antagonist 3)  HGNC  Alliance
Mus musculus (house mouse) : Spry3 (sprouty RTK signaling antagonist 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spry3 (sprouty RTK signaling antagonist 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SPRY3 (sprouty RTK signaling antagonist 3)
Canis lupus familiaris (dog) : SPRY3 (sprouty RTK signaling antagonist 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spry3 (sprouty RTK signaling antagonist 3)
Sus scrofa (pig) : SPRY3 (sprouty RTK signaling antagonist 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01218,930,087 - 18,940,622 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01220,923,714 - 20,933,886 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41217,343,080 - 17,344,990 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1218,607,973 - 18,609,883 (+)NCBICelera
Cytogenetic Map12q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Spry3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1562172
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.