Cmklr1 (chemerin chemokine-like receptor 1) - Rat Genome Database

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Gene: Cmklr1 (chemerin chemokine-like receptor 1) Rattus norvegicus
Analyze
Symbol: Cmklr1
Name: chemerin chemokine-like receptor 1
RGD ID: 69359
Description: Predicted to enable adipokinetic hormone binding activity; adipokinetic hormone receptor activity; and transmembrane signaling receptor activity. Predicted to be involved in several processes, including positive regulation of cold-induced thermogenesis; positive regulation of macrophage chemotaxis; and regulation of gene expression. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human CMKLR1 (chemerin chemokine-like receptor 1); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 17beta-hydroxy-5alpha-androstan-3-one.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: chemerin-like receptor 1; chemokine receptor-like 1; chemokine-like receptor 1; G-protein coupled chemoattractant-like receptor; G-protein coupled receptor DEZ
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21242,974,462 - 43,027,321 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1242,974,410 - 43,028,129 (+)Ensembl
Rnor_6.01248,743,556 - 48,796,582 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,789,261 - 48,793,553 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01250,531,209 - 50,584,406 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41244,056,527 - 44,061,043 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11243,921,991 - 43,923,110 (+)NCBI
Celera1244,621,019 - 44,625,349 (+)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. CMKLR1 deficiency influences glucose tolerance and thermogenesis in mice on high fat diet. Huang C, etal., Biochem Biophys Res Commun. 2016 Apr 29;473(2):435-41. doi: 10.1016/j.bbrc.2016.03.026. Epub 2016 Mar 10.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Molecular cloning and tissue distribution of cDNA encoding a novel chemoattractant-like receptor. Owman C, etal., Biochem Biophys Res Commun 1997 Dec 18;241(2):390-4.
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14530373   PMID:15753205   PMID:17033093   PMID:17635925   PMID:19443732   PMID:22796467   PMID:23154239   PMID:25471554   PMID:27371688   PMID:27742615   PMID:27860453   PMID:30257454  
PMID:30595125   PMID:31965243   PMID:32462328   PMID:34461109   PMID:34769243  


Genomics

Comparative Map Data
Cmklr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21242,974,462 - 43,027,321 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1242,974,410 - 43,028,129 (+)Ensembl
Rnor_6.01248,743,556 - 48,796,582 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,789,261 - 48,793,553 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01250,531,209 - 50,584,406 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41244,056,527 - 44,061,043 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11243,921,991 - 43,923,110 (+)NCBI
Celera1244,621,019 - 44,625,349 (+)NCBICelera
Cytogenetic Map12q16NCBI
CMKLR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812108,288,046 - 108,339,311 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl12108,288,044 - 108,339,317 (-)EnsemblGRCh38hg38GRCh38
GRCh3712108,681,823 - 108,733,088 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612107,209,477 - 107,257,212 (-)NCBINCBI36hg18NCBI36
Build 3412107,187,813 - 107,235,553NCBI
Celera12108,351,249 - 108,402,507 (-)NCBI
Cytogenetic Map12q23.3NCBI
HuRef12105,746,498 - 105,797,979 (-)NCBIHuRef
CHM1_112108,647,879 - 108,699,141 (-)NCBICHM1_1
T2T-CHM13v2.012108,256,268 - 108,307,509 (-)NCBI
Cmklr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395113,750,415 - 113,792,971 (-)NCBIGRCm39mm39
GRCm39 Ensembl5113,750,415 - 113,788,487 (-)Ensembl
GRCm385113,612,355 - 113,650,475 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5113,612,354 - 113,650,426 (-)EnsemblGRCm38mm10GRCm38
MGSCv375114,062,364 - 114,100,399 (-)NCBIGRCm37mm9NCBIm37
MGSCv365113,873,360 - 113,911,389 (-)NCBImm8
Celera5110,714,182 - 110,752,271 (-)NCBICelera
Cytogenetic Map5FNCBI
Cmklr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554559,589,822 - 9,590,937 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554559,587,421 - 9,638,602 (-)NCBIChiLan1.0ChiLan1.0
CMKLR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112109,256,329 - 109,307,526 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12109,260,130 - 109,261,271 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v012105,859,702 - 105,911,010 (-)NCBIMhudiblu_PPA_v0panPan3
CMKLR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12618,487,700 - 18,539,678 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2618,532,479 - 18,533,576 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2617,254,935 - 17,309,701 (-)NCBI
ROS_Cfam_1.02618,836,295 - 18,888,040 (+)NCBI
ROS_Cfam_1.0 Ensembl2618,836,443 - 18,884,494 (+)Ensembl
UMICH_Zoey_3.12617,467,315 - 17,495,005 (-)NCBI
UNSW_CanFamBas_1.02618,824,230 - 18,875,966 (+)NCBI
UU_Cfam_GSD_1.02618,845,535 - 18,897,317 (+)NCBI
Cmklr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118145,171,728 - 145,175,406 (+)NCBI
SpeTri2.0NW_004936769302,391 - 304,166 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CMKLR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1442,420,176 - 42,468,065 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11442,420,166 - 42,468,080 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21444,964,240 - 44,977,991 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.21445,116,776 - 45,118,925 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap14q21.1NCBI
CMKLR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111103,484,422 - 103,536,273 (-)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037141,555,941 - 141,609,279 (+)NCBIVero_WHO_p1.0
Cmklr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474711,553,268 - 11,601,105 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
BI280015  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21243,023,664 - 43,023,868 (+)MAPPERmRatBN7.2
Rnor_6.01248,792,926 - 48,793,129NCBIRnor6.0
Rnor_5.01250,580,750 - 50,580,953UniSTSRnor5.0
RGSC_v3.41244,060,416 - 44,060,619UniSTSRGSC3.4
Celera1244,624,722 - 44,624,925UniSTS
Cytogenetic Map12q16UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)122806443345899022Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)122806443346669029Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123210317445899022Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:148
Count of miRNA genes:112
Interacting mature miRNAs:126
Transcripts:ENSRNOT00000000893
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 3 3 11
Low 3 41 57 41 16 41 8 11 74 35 38 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000000893   ⟹   ENSRNOP00000000893
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1242,974,410 - 43,028,129 (+)Ensembl
Rnor_6.0 Ensembl1248,789,261 - 48,793,553 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097365   ⟹   ENSRNOP00000089521
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1243,009,352 - 43,028,129 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000101222   ⟹   ENSRNOP00000085339
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1243,003,952 - 43,028,129 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000105285   ⟹   ENSRNOP00000091942
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1242,984,998 - 43,028,129 (+)Ensembl
RefSeq Acc Id: NM_022218   ⟹   NP_071554
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21243,020,000 - 43,024,292 (+)NCBI
Rnor_6.01248,789,261 - 48,793,553 (+)NCBI
Rnor_5.01250,531,209 - 50,584,406 (+)NCBI
RGSC_v3.41244,056,527 - 44,061,043 (+)RGD
Celera1244,621,019 - 44,625,349 (+)RGD
Sequence:
RefSeq Acc Id: XM_006249505   ⟹   XP_006249567
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21243,009,703 - 43,027,321 (+)NCBI
Rnor_6.01248,778,897 - 48,796,582 (+)NCBI
Rnor_5.01250,531,209 - 50,584,406 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006249506   ⟹   XP_006249568
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21243,005,812 - 43,027,321 (+)NCBI
Rnor_6.01248,778,870 - 48,796,582 (+)NCBI
Rnor_5.01250,531,209 - 50,584,406 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006249507   ⟹   XP_006249569
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21243,003,487 - 43,027,321 (+)NCBI
Rnor_6.01248,772,821 - 48,796,582 (+)NCBI
Rnor_5.01250,531,209 - 50,584,406 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006249508   ⟹   XP_006249570
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21242,984,946 - 43,027,321 (+)NCBI
Rnor_6.01248,754,214 - 48,796,582 (+)NCBI
Rnor_5.01250,531,209 - 50,584,406 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006249509   ⟹   XP_006249571
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21242,974,462 - 43,027,321 (+)NCBI
Rnor_6.01248,743,556 - 48,796,582 (+)NCBI
Rnor_5.01250,531,209 - 50,584,406 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_071554   ⟸   NM_022218
- UniProtKB: G3V625 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249571   ⟸   XM_006249509
- Peptide Label: isoform X1
- UniProtKB: G3V625 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249570   ⟸   XM_006249508
- Peptide Label: isoform X1
- UniProtKB: G3V625 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249569   ⟸   XM_006249507
- Peptide Label: isoform X1
- UniProtKB: G3V625 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249567   ⟸   XM_006249505
- Peptide Label: isoform X1
- UniProtKB: G3V625 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249568   ⟸   XM_006249506
- Peptide Label: isoform X1
- UniProtKB: G3V625 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000000893   ⟸   ENSRNOT00000000893
RefSeq Acc Id: ENSRNOP00000089521   ⟸   ENSRNOT00000097365
RefSeq Acc Id: ENSRNOP00000085339   ⟸   ENSRNOT00000101222
RefSeq Acc Id: ENSRNOP00000091942   ⟸   ENSRNOT00000105285

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35786-F1-model_v2 AlphaFold O35786 1-372 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
12 48791564 48791565 G A snv CDR, MR/N (2020), MR/N (MCW)


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
12 50579388 50579389 G A snv MR/N (KNAW)


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
12 44059054 44059055 G A snv MR/N (KNAW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69359 AgrOrtholog
BioCyc Gene G2FUF-18915 BioCyc
Ensembl Genes ENSRNOG00000000704 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000000893 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000085339 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000089521 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000091942 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000000893 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000097365 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000101222 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000105285 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Chemokine-like_recpt_1 UniProtKB/Swiss-Prot
  Formyl_rcpt-rel UniProtKB/Swiss-Prot
  GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
KEGG Report rno:60669 UniProtKB/Swiss-Prot
NCBI Gene 60669 ENTREZGENE
PANTHER PTHR24225 UniProtKB/Swiss-Prot
  PTHR24225:SF49 UniProtKB/Swiss-Prot
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen Cmklr1 PhenoGen
PRINTS DEZORPHANR UniProtKB/Swiss-Prot
  GPCRRHODOPSN UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
UniProt CML1_RAT UniProtKB/Swiss-Prot
  G3V625 ENTREZGENE
  O35786 ENTREZGENE
UniProt Secondary G3V625 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-15 Cmklr1  chemerin chemokine-like receptor 1  Cmklr1  chemokine-like receptor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Cmklr1  chemokine-like receptor 1      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in heart and lung and at lower levels in small intestine, colon, kidney, liver, uterus, and brain 68788
gene_expression expressed primarily in vascular cells in liver and kidney 68788