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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | RGD:733439 | 6480464 | 1, 2-Dimethylhydrazine results in decreased expression of CMKLR1 mRNA | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | ISO | RGD:1348723 | 6480464 | [Estradiol binds to ESR2 protein] which results in increased expression of CMKLR1 mRNA | CTD | PMID:20404318 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CMKLR1 mRNA | CTD | PMID:32741896 | 17beta-estradiol 3-benzoate | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CMKLR1 mRNA | CTD | PMID:32741896 | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | EXP | | 6480464 | Dihydrotestosterone results in increased expression of CMKLR1 mRNA | CTD | PMID:22948218 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:733439 | 6480464 | Tetrachlorodibenzodioxin affects the expression of CMKLR1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CMKLR1 mRNA | CTD | PMID:27913140, PMID:33387578 | 8-Br-cAMP | increases expression | ISO | RGD:1348723 | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CMKLR1 mRNA | CTD | PMID:20147733 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of CMKLR1 mRNA | CTD | PMID:31881176 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of CMKLR1 mRNA | CTD | PMID:33354967 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of CMKLR1 mRNA | CTD | PMID:16483693 | antirheumatic drug | decreases expression | ISO | RGD:1348723 | 6480464 | Antirheumatic Agents results in decreased expression of CMKLR1 mRNA | CTD | PMID:24449571 | arsenous acid | decreases expression | ISO | RGD:1348723 | 6480464 | Arsenic Trioxide results in decreased expression of CMKLR1 mRNA | CTD | PMID:25258189 | benzo[a]pyrene | affects methylation | ISO | RGD:1348723 | 6480464 | Benzo(a)pyrene affects the methylation of CMKLR1 5' UTR, Benzo(a)pyrene affects the methylation of CMKLR1 promoter | CTD | PMID:27901495 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CMKLR1 mRNA | CTD | PMID:25181051, PMID:34947998 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of CMKLR1 gene | CTD | PMID:28505145 | bisphenol F | increases expression | ISO | RGD:733439 | 6480464 | bisphenol F results in increased expression of CMKLR1 mRNA | CTD | PMID:30951980 | chloroprene | decreases expression | ISO | RGD:733439 | 6480464 | Chloroprene results in decreased expression of CMKLR1 mRNA | CTD | PMID:23125180 | cisplatin | multiple interactions | ISO | RGD:1348723 | 6480464 | [Cisplatin results in decreased susceptibility to Cisplatin] which results in increased expression of CMKLR1 mRNA | CTD | PMID:30871063 | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of CMKLR1 mRNA | CTD | PMID:23914054 | diarsenic trioxide | decreases expression | ISO | RGD:1348723 | 6480464 | Arsenic Trioxide results in decreased expression of CMKLR1 mRNA | CTD | PMID:25258189 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of CMKLR1 mRNA | CTD | PMID:21266533 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of CMKLR1 mRNA | CTD | PMID:17379624 | dichlorine | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in decreased expression of CMKLR1 mRNA | CTD | PMID:18636392 | doxorubicin | decreases expression | ISO | RGD:1348723 | 6480464 | Doxorubicin results in decreased expression of CMKLR1 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of CMKLR1 mRNA | CTD | PMID:29391264 | entinostat | increases expression | ISO | RGD:1348723 | 6480464 | entinostat results in increased expression of CMKLR1 mRNA | CTD | PMID:32870474 | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of CMKLR1 mRNA | CTD | PMID:30307764 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of CMKLR1 mRNA | CTD | PMID:33387578 | graphite | affects expression | EXP | | 6480464 | Graphite affects the expression of CMKLR1 mRNA | CTD | PMID:29933104 | lipopolysaccharide | decreases expression | ISO | RGD:733439 | 6480464 | Lipopolysaccharides results in decreased expression of CMKLR1 mRNA | CTD | PMID:12057914 | Monobutylphthalate | affects expression | ISO | RGD:733439 | 6480464 | monobutyl phthalate affects the expression of CMKLR1 mRNA | CTD | PMID:19162170 | monosodium L-glutamate | decreases expression | ISO | RGD:733439 | 6480464 | Sodium Glutamate results in decreased expression of CMKLR1 mRNA | CTD | PMID:22078008 | N-methyl-4-phenylpyridinium | increases expression | ISO | RGD:1348723 | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of CMKLR1 mRNA | CTD | PMID:32870474 | nickel atom | increases expression | ISO | RGD:1348723 | 6480464 | Nickel results in increased expression of CMKLR1 mRNA | CTD | PMID:24768652 | nickel atom | decreases expression | ISO | RGD:1348723 | 6480464 | Nickel results in decreased expression of CMKLR1 mRNA | CTD | PMID:23195993 | ozone | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in decreased expression of CMKLR1 mRNA | CTD | PMID:18636392 | ozone | increases expression | ISO | RGD:733439 | 6480464 | Ozone results in increased expression of CMKLR1 mRNA | CTD | PMID:31626304 | ozone | decreases expression | ISO | RGD:733439 | 6480464 | Ozone results in decreased expression of CMKLR1 mRNA | CTD | PMID:29471542 | paracetamol | affects expression | ISO | RGD:733439 | 6480464 | Acetaminophen affects the expression of CMKLR1 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of CMKLR1 mRNA | CTD | PMID:33387578 | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of CMKLR1 mRNA | CTD | PMID:17077588 | phorbol 13-acetate 12-myristate | multiple interactions | ISO | RGD:1348723 | 6480464 | [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CMKLR1 mRNA | CTD | PMID:16979875 | pirinixic acid | decreases expression | ISO | RGD:733439 | 6480464 | pirinixic acid results in decreased expression of CMKLR1 mRNA | CTD | PMID:17950772 | progesterone | decreases expression | EXP | | 6480464 | Progesterone results in decreased expression of CMKLR1 mRNA | CTD | PMID:20726854 | rotenone | increases expression | ISO | RGD:1348723 | 6480464 | Rotenone results in increased expression of CMKLR1 mRNA | CTD | PMID:29955902, PMID:32870474 | sodium arsenite | affects methylation | ISO | RGD:1348723 | 6480464 | sodium arsenite affects the methylation of CMKLR1 gene | CTD | PMID:28589171 | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of CMKLR1 mRNA | CTD | PMID:19281266 | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of CMKLR1 mRNA | CTD | PMID:19281266 | testosterone | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CMKLR1 mRNA | CTD | PMID:32741896 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of CMKLR1 mRNA | CTD | PMID:34492290 | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of CMKLR1 gene | CTD | PMID:27618143 | triclosan | decreases expression | ISO | RGD:1348723 | 6480464 | Triclosan results in decreased expression of CMKLR1 mRNA | CTD | PMID:30510588 | triptonide | increases expression | ISO | RGD:733439 | 6480464 | triptonide results in increased expression of CMKLR1 mRNA | CTD | PMID:33045310 | valproic acid | affects expression | ISO | RGD:1348723 | 6480464 | Valproic Acid affects the expression of CMKLR1 mRNA | CTD | PMID:25979313 | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of CMKLR1 mRNA | CTD | PMID:23869203 | zinc atom | multiple interactions | ISO | RGD:1348723 | 6480464 | [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CMKLR1 mRNA | CTD | PMID:16979875 | zinc atom | decreases expression | ISO | RGD:1348723 | 6480464 | Zinc deficiency results in decreased expression of CMKLR1 mRNA | CTD | PMID:18356318 | zinc(0) | multiple interactions | ISO | RGD:1348723 | 6480464 | [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CMKLR1 mRNA | CTD | PMID:16979875 | zinc(0) | decreases expression | ISO | RGD:1348723 | 6480464 | Zinc deficiency results in decreased expression of CMKLR1 mRNA | CTD | PMID:18356318 | |