 Gene-Chemical Interaction Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations |
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Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
 Gene Annotator (Annotation Distribution) unavailable |
 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
 Gviewer (Genome Viewer) unavailable |
 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
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Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Gene Ontology AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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References - curated| 1. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | Huang C, etal., Biochem Biophys Res Commun. 2016 Apr 29;473(2):435-41. doi: 10.1016/j.bbrc.2016.03.026. Epub 2016 Mar 10. |
| 3. | MGD data from the GO Consortium |
| 4. | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 5. | Owman C, etal., Biochem Biophys Res Commun 1997 Dec 18;241(2):390-4. |
| 6. | RGD automated data pipeline |
| 7. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 8. | RGD automated import pipeline for gene-chemical interactions |
References - uncurated| PubMed | 14530373 15753205 17033093 17635925 19443732 22796467 23154239 25471554 27371688 27742615 27860453 30257454 30595125 |
Genomics
Comparative Map Data| Cmklr1 (Rattus norvegicus - Norway rat) |
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| CMKLR1 (Homo sapiens - human) |
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| Cmklr1 (Mus musculus - house mouse) |
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| Cmklr1 (Chinchilla lanigera - long-tailed chinchilla) |
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| CMKLR1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| CMKLR1 (Canis lupus familiaris - dog) |
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| Cmklr1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| CMKLR1 (Sus scrofa - pig) |
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| CMKLR1 (Chlorocebus sabaeus - African green monkey) |
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| Cmklr1 (Heterocephalus glaber - naked mole-rat) |
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Position Markers| BI280015 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | 2 | 3 | 3 | 11 | |||||||||
| Low | 3 | 41 | 57 | 41 | 16 | 41 | 8 | 11 | 74 | 35 | 38 | 8 | |
| Below cutoff |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_022218 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_006249505 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006249506 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006249507 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006249508 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006249509 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AAHX01073034 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AAHX01073035 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AC128917 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AJ002745 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CB707803 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473973 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | ENSRNOT00000000893 ⟹ ENSRNOP00000000893 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_022218 ⟹ NP_071554 | ||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
GTATTTCTAGCCGTGCACAGTGACTGATCAGCCGAGGACCTACCCTCGAGTTCTATTCTGCAAChide sequence |
| RefSeq Acc Id: | XM_006249505 ⟹ XP_006249567 | ||||||||||||
| RefSeq Status: | |||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Sequence: |
GAGAGAGAGAGAGAGAGAGAGAGAGAGAGAAGCAGCTGCCAGGAGCCCAGGTGCTTGCAAAGGThide sequence |
| RefSeq Acc Id: | XM_006249506 ⟹ XP_006249568 | ||||||||||||
| RefSeq Status: | |||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Sequence: |
AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAAGCAGCThide sequence |
| RefSeq Acc Id: | XM_006249507 ⟹ XP_006249569 | ||||||||||||
| RefSeq Status: | |||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Sequence: |
GAACAAAACCTTGTGTATGCTTGTGTGCATGTGTGTACTCTTTTCTGAGACATGATCCTTCCCChide sequence |
| RefSeq Acc Id: | XM_006249508 ⟹ XP_006249570 | ||||||||||||
| RefSeq Status: | |||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Sequence: |
CCTGGCTGCCAGGCACAGCCTCCTCTAGTGGCCCCCACCCCACACAGCTGGCGCCCCCGCCCTChide sequence |
| RefSeq Acc Id: | XM_006249509 ⟹ XP_006249571 | ||||||||||||
| RefSeq Status: | |||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Sequence: |
TGCCTTGCTGTCCTGTTTGTAGACCGTCTCGCTGCACAATCCAGGTGGGCTTTCAACTTTGTGGhide sequence |
Protein Sequences| Protein RefSeqs | NP_071554 | (Get FASTA) | NCBI Sequence Viewer |
| XP_006249567 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006249568 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006249569 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006249570 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006249571 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | CAA05715 | (Get FASTA) | NCBI Sequence Viewer |
| EDM13970 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM13971 | (Get FASTA) | NCBI Sequence Viewer | |
| O35786 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_071554 ⟸ NM_022218 |
| - UniProtKB: | G3V625 (UniProtKB/TrEMBL) |
| - Sequence: |
MEYEGYNDSSIYGEEYSDGSDYIVDLEEAGPLEAKVAEVFLVVIYSLVCFLGILGNGLVIVIAThide sequence |
| RefSeq Acc Id: | XP_006249571 ⟸ XM_006249509 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | G3V625 (UniProtKB/TrEMBL) |
| - Sequence: |
MEYEGYNDSSIYGEEYSDGSDYIVDLEEAGPLEAKVAEVFLVVIYSLVCFLGILGNGLVIVIAThide sequence |
| RefSeq Acc Id: | XP_006249570 ⟸ XM_006249508 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | G3V625 (UniProtKB/TrEMBL) |
| - Sequence: |
MEYEGYNDSSIYGEEYSDGSDYIVDLEEAGPLEAKVAEVFLVVIYSLVCFLGILGNGLVIVIAThide sequence |
| RefSeq Acc Id: | XP_006249569 ⟸ XM_006249507 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | G3V625 (UniProtKB/TrEMBL) |
| - Sequence: |
MEYEGYNDSSIYGEEYSDGSDYIVDLEEAGPLEAKVAEVFLVVIYSLVCFLGILGNGLVIVIAThide sequence |
| RefSeq Acc Id: | XP_006249567 ⟸ XM_006249505 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | G3V625 (UniProtKB/TrEMBL) |
| - Sequence: |
MEYEGYNDSSIYGEEYSDGSDYIVDLEEAGPLEAKVAEVFLVVIYSLVCFLGILGNGLVIVIAThide sequence |
| RefSeq Acc Id: | XP_006249568 ⟸ XM_006249506 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | G3V625 (UniProtKB/TrEMBL) |
| - Sequence: |
MEYEGYNDSSIYGEEYSDGSDYIVDLEEAGPLEAKVAEVFLVVIYSLVCFLGILGNGLVIVIAThide sequence |
| RefSeq Acc Id: | ENSRNOP00000000893 ⟸ ENSRNOT00000000893 |
Protein Domains
G_PROTEIN_RECEP_F1_2
TranscriptomeStrain Variation
Strain Sequence Variants (Rnor 6.0)
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Damaging VariantsAssembly: Rnor_5.0
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 12 | 50579388 | 50579389 | G | A | snv | MR/N (KNAW) |
Assembly: Rnor_6.0
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 12 | 48791564 | 48791565 | G | A | snv | MR/N (MCW), CDR |
Assembly: RGSC_v3.4
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 12 | 44059054 | 44059055 | G | A | snv | MR/N (KNAW) |
Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:69359 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000000704 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000000893 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000000893 | ENTREZGENE, UniProtKB/TrEMBL |
| InterPro | Chemokine-like_recpt_1 | UniProtKB/Swiss-Prot |
| Formyl_rcpt-rel | UniProtKB/Swiss-Prot | |
| GPCR_Rhodpsn | UniProtKB/Swiss-Prot | |
| GPCR_Rhodpsn_7TM | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:60669 | UniProtKB/TrEMBL |
| NCBI Gene | 60669 | ENTREZGENE |
| PANTHER | PTHR24225 | UniProtKB/Swiss-Prot |
| PTHR24225:SF49 | UniProtKB/Swiss-Prot | |
| Pfam | 7tm_1 | UniProtKB/Swiss-Prot |
| PhenoGen | Cmklr1 | PhenoGen |
| PRINTS | DEZORPHANR | UniProtKB/Swiss-Prot |
| GPCRRHODOPSN | UniProtKB/Swiss-Prot | |
| PROSITE | G_PROTEIN_RECEP_F1_1 | UniProtKB/Swiss-Prot |
| G_PROTEIN_RECEP_F1_2 | UniProtKB/Swiss-Prot | |
| UniGene | Rn.44465 | ENTREZGENE |
| UniProt | CML1_RAT | UniProtKB/Swiss-Prot |
| G3V625 | ENTREZGENE, UniProtKB/TrEMBL | |
| O35786 | ENTREZGENE |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2016-04-15 | Cmklr1 | chemerin chemokine-like receptor 1 | Cmklr1 | chemokine-like receptor 1 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2002-06-10 | Cmklr1 | chemokine-like receptor 1 | Name updated | 70584 | APPROVED |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_expression | expressed in heart and lung and at lower levels in small intestine, colon, kidney, liver, uterus, and brain | 68788 |
| gene_expression | expressed primarily in vascular cells in liver and kidney | 68788 |
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| More on Cmklr1 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 69359 |
| Created: | 2001-11-14 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-03-04 |
| Status: | ACTIVE |
