Vom2r64 (vomeronasal 2 receptor, 64) - Rat Genome Database

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Gene: Vom2r64 (vomeronasal 2 receptor, 64) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Vom2r64
Name: vomeronasal 2 receptor, 64
RGD ID: 1584665
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane; INTERACTS WITH bisphenol A; tributylstannane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC681079; similar to putative pheromone receptor (Go-VN5)
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Pseudogenes: Vom2r-ps141  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81224,123,536 - 24,153,307 (+)NCBIGRCr8
mRatBN7.21218,419,409 - 18,449,218 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1218,419,326 - 18,449,218 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1219,832,346 - 19,864,379 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01220,456,562 - 20,488,595 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01219,520,886 - 19,552,919 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01220,943,936 - 20,978,110 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1220,943,936 - 21,077,539 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01222,984,152 - 23,015,272 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41218,701,953 - 18,732,104 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic Map12q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vom2r64Ratbisphenol A multiple interactionsEXP 6480464[bisphenol A co-treated with tributyltin] results in decreased expression of VOM2R64 mRNACTDPMID:31129395
Vom2r64Rattributylstannane multiple interactionsEXP 6480464[bisphenol A co-treated with tributyltin] results in decreased expression of VOM2R64 mRNACTDPMID:31129395


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vom2r64RatG protein-coupled receptor signaling pathway involved_inIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Vom2r64RatG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR000068 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Vom2r64Ratsignal transduction involved_inIEAUniProtKB-KW:KW-08071600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vom2r64Ratmembrane located_inIEAInterPro:IPR000068 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Vom2r64Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Vom2r64Ratplasma membrane is_active_inIBAMGI:2429498 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Vom2r64Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Vom2r64Ratplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vom2r64RatG protein-coupled receptor activity enablesIEAInterPro:IPR000068 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Vom2r64RatG protein-coupled receptor activity enablesIBAMGI:2429498 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Vom2r64RatG protein-coupled receptor activity enablesIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
PMID:17382427  



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Variants in Vom2r64
1002 total Variants

Predicted Target Of
Summary Value
Count of predictions:312
Count of miRNA genes:149
Interacting mature miRNAs:159
Transcripts:ENSRNOT00000041089, ENSRNOT00000041490, ENSRNOT00000042677, ENSRNOT00000071011, ENSRNOT00000071324, ENSRNOT00000072820
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 48 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
61443Btemp2Thermal response to stress QTL 23.30.000094body temperature trait (VT:0005535)core body temperature (CMO:0001036)121502518320794014Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat

1 to 10 of 48 rows



circulatory system
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
reproductive system
respiratory system
1 6 8 3 6 3 10 7 4 5



Ensembl Acc Id: ENSRNOT00000042677   ⟹   ENSRNOP00000051492
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1220,943,942 - 21,077,539 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000071324   ⟹   ENSRNOP00000064569
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1220,943,936 - 20,978,110 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000072820   ⟹   ENSRNOP00000065801
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1220,943,936 - 20,978,110 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105559   ⟹   ENSRNOP00000081007
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1218,419,326 - 18,449,218 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117241   ⟹   ENSRNOP00000081293
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1218,419,326 - 18,449,218 (+)Ensembl
RefSeq Acc Id: NM_001099513   ⟹   NP_001092983
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,123,536 - 24,153,307 (+)NCBI
mRatBN7.21218,419,409 - 18,449,218 (+)NCBI
Rnor_6.01220,943,936 - 20,978,110 (-)NCBI
Rnor_5.01222,984,152 - 23,015,272 (-)NCBI
RGSC_v3.41218,701,953 - 18,732,104 (-)RGD
Sequence:
RefSeq Acc Id: XM_063271651   ⟹   XP_063127721
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,123,536 - 24,153,307 (+)NCBI
Protein RefSeqs NP_001092983 (Get FASTA)   NCBI Sequence Viewer  
  NP_001417434 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127721 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000081007.1
  ENSRNOP00000081293.1
  ENSRNOP00000111816
RefSeq Acc Id: NP_001092983   ⟸   NM_001099513
- Peptide Label: precursor
- UniProtKB: A0A8I5ZR06 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000065801   ⟸   ENSRNOT00000072820
Ensembl Acc Id: ENSRNOP00000064569   ⟸   ENSRNOT00000071324
Ensembl Acc Id: ENSRNOP00000051492   ⟸   ENSRNOT00000042677
Ensembl Acc Id: ENSRNOP00000081007   ⟸   ENSRNOT00000105559
G-protein coupled receptors family 3 profile

Name Modeler Protein Id AA Range Protein Structure
AF-M0R8K5-F1-model_v2 AlphaFold M0R8K5 1-855 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 33 of 33 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-19743 BioCyc
Ensembl Genes ENSRNOG00000047568 Ensembl
  ENSRNOG00000064916 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000080595 ENTREZGENE
Ensembl Transcript ENSRNOT00000105559.1 UniProtKB/TrEMBL
  ENSRNOT00000117241.1 UniProtKB/TrEMBL
  ENSRNOT00000142672 ENTREZGENE
Gene3D-CATH 2.10.50.30 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  GPCR_3 UniProtKB/TrEMBL
  GPCR_3_9-Cys_dom UniProtKB/TrEMBL
  GPCR_3_9-Cys_sf UniProtKB/TrEMBL
  GPCR_3_C UniProtKB/TrEMBL
  GPCR_3_Ca_sens_rcpt-rel UniProtKB/TrEMBL
  GPCR_3_vmron_rcpt_2 UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
NCBI Gene 681079 ENTREZGENE
PANTHER PTHR24061 UniProtKB/TrEMBL
  VOMERONASAL 2, RECEPTOR 118-RELATED UniProtKB/TrEMBL
Pfam 7tm_3 UniProtKB/TrEMBL
  ANF_receptor UniProtKB/TrEMBL
  NCD3G UniProtKB/TrEMBL
PhenoGen Vom2r64 PhenoGen
PRINTS GPCRMGR UniProtKB/TrEMBL
  VOMERONASL2R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F3_4 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047568 RatGTEx
  ENSRNOG00000064916 RatGTEx
  ENSRNOG00000080595 RatGTEx
Superfamily-SCOP SSF53822 UniProtKB/TrEMBL
UniProt A0A8I5ZR06 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZSN0 ENTREZGENE, UniProtKB/TrEMBL
1 to 33 of 33 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-07-23 Vom2r64  vomeronasal 2 receptor, 64  LOC681079  similar to putative pheromone receptor (Go-VN5)  Symbol and Name updated 1299863 APPROVED
2006-11-19 LOC681079  similar to putative pheromone receptor (Go-VN5)      Symbol and Name status set to provisional 70820 PROVISIONAL