Pigfal17 QTL Report (Rattus norvegicus) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: Pigfal17 (Plasma insulin-like growth factor 1 level QTL 17) Rattus norvegicus

Symbol: Pigfal17
Name: Plasma insulin-like growth factor 1 level QTL 17
RGD ID: 8552964
Trait: blood insulin-like growth factor amount   (VT:0010479)    
Measurement Type: plasma insulin-like growth factor 1 level   (CMO:0001299)    
LOD Score: 3.5
P Value: Not Available
Variance: 2.6
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81211,200,494 - 52,308,831RGD_MAPPER_PIPELINE
mRatBN7.2125,564,495 - 46,669,029RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0129,223,626 - 52,716,770RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01211,147,460 - 54,450,796RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4126,630,242 - 46,782,294RGD_MAPPER_PIPELINERGSC3.4
Cross Type: intercross
Strains Crossed: F344/IcoCrlf LOU/NimrOlaHsd 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal17Ratdisease of metabolism  IAGP 7794844 RGD 
Pigfal17RatInsulin-Like Growth Factor I Deficiency  IAGP 7794844 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal17Ratabnormal circulating insulin-like growth factor I level  IDA 7794844 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal17Ratplasma insulin-like growth factor 1 level  IDA 7794844 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal17Ratcontrolled calorie content diet  IDA 7794844 RGD 
Pigfal17Ratfasting  IDA 7794844 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal17Ratradioimmunoassay  IDA 7794844 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal17RatF344/IcoCrlf  IEA 7794844 RGD 
Pigfal17RatLOU/NimrOlaHsd  IEA 7794844 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal17Ratblood insulin-like growth factor amount  IDA 7794844 RGD 


#
Reference Title
Reference Citation
1. QTLs influencing IGF-1 levels in a LOU/CxFischer 344F2 rat population. Tracks towards the metabolic theory of Ageing. Marissal-Arvy N, etal., Growth Horm IGF Res. 2013 Dec;23(6):220-8. doi: 10.1016/j.ghir.2013.08.002. Epub 2013 Aug 19.


1 to 20 of 887 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1560846Tex26testis expressed 261255736915605209Rat
1307396Medagmesenteric estrogen-dependent adipogenesis1256131915634583Rat
41238510Rpl28-ps11ribosomal protein L28, pseudogene 111256501915651868Rat
7626408LOC102551556uncharacterized LOC1025515561256529055656673Rat
41269287LOC120096091U4 spliceosomal RNA1257218415721973Rat
2097Alox5aparachidonate 5-lipoxygenase activating protein1257489415772986Rat
7570662LOC102551736uncharacterized LOC1025517361257955875800442Rat
41282038LOC120095879uncharacterized LOC1200958791257994835804796Rat
9177507Rps19l6ribosomal protein S19 like 61258076915808050Rat
11366571Trnan-guu11transfer RNA asparagine (anticodon GUU) 111258151765815249Rat
1310835Uspl1ubiquitin specific peptidase like 11258234605850470Rat
11363195LOC108352413uncharacterized LOC1083524131258720435884746Rat
41369369LOC120096113small nucleolar RNA SNORA381259231965923336Rat
2802Hmgb1high mobility group box 11259729505979658Rat
41351322Rpl18-ps15ribosomal protein L18, pseudogene 151260048556020163Rat
7721386LOC102554603uncharacterized LOC1025546031260368536072289Rat
9247033Rpl35a-ps8ribosomal protein L35A, pseudogene 81260722796072780Rat
7724641LOC102554734uncharacterized LOC1025547341260790146081600Rat
1359252Katnal1katanin catalytic subunit A1 like 11260946636156114Rat
7625496LOC102553253uncharacterized LOC1025532531261583856168368Rat

1 to 20 of 887 rows
1 to 20 of 1340 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10125DXMgh7230123381916733819400Ratregion
10888D12Wox1089122089438020894469Ratregion
10990D12Mco2242123871454038714782Ratregion
11051D12Mit2217121961087019611091Ratregion
11052D12Wox11200121961088619611090Ratregion
11053D12Wox12202121961088919611095Ratregion
33911D12Mit6139121235161912351758Ratregion
33955D1Mit22124123140994231410080Ratregion
33961D12Mit5133121235161912351752Ratregion
33963D12Mit4198123819280938193007Ratregion
34017D12Mit9142122184936621849508Ratregion
34070D12Mgh7138123569808835698226Ratregion
34086D12Mgh9135124021838040218516Ratregion
34246D12Mgh3118122423477724234895Ratregion
34389D12Mgh10132123769148537691617Ratregion
34417D12Mgh2163121983578919835952Ratregion
34729D12Mgh5124122806443328064557Ratregion
11281D12Wox15157123609153336091690Ratregion
11282D12Arb7340123609137936091727Ratregion
11396D12Mgh11150124164428741644437Ratregion
1 to 20 of 1340 rows

Peak: (D12Mgh5)
Rat AssemblyChrPosition (strand)Source
GRCr81233,700,432 - 33,700,556 (+)Marker Load Pipeline
mRatBN7.21228,064,433 - 28,064,557 (+)MAPPER
Rnor_6.01231,723,565 - 31,723,688NCBI
Rnor_5.01233,647,399 - 33,647,522UniSTS
RGSC_v3.41229,130,181 - 29,130,304UniSTS
RGSC_v3.41229,130,180 - 29,130,304RGD
RGSC_v3.11228,993,569 - 28,993,692RGD
Celera1229,756,877 - 29,756,993UniSTS
RH 3.4 Map12466.8UniSTS
RH 3.4 Map12466.8RGD
RH 2.0 Map12343.2RGD
SHRSP x BN Map1231.95RGD
Cytogenetic Map12 RGD


1 to 10 of 73 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
61443Btemp2Thermal response to stress QTL 23.30.000094body temperature trait (VT:0005535)core body temperature (CMO:0001036)121502518320794014Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122308134044726024Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12931821612829686Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
737822Alc10Alcohol consumption QTL 102.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)121961087040218516Rat

1 to 10 of 73 rows


Note Type Note Reference
qtl_general number of animals used: 94 F2 females 7794844
qtl_general software package used: ANOVA; MultiQTL software 7794844
qtl_general measurement method: 4 weeks old rats were fed SAFE-A03 chow; at 18 weeks of age they were fasted overnight, decapitated in the morning and blood samples taken; total Igf-1 level determined by radioimmunoassay 7794844
qtl_general confidence interval from 57.00-60.45 Mb 7794844