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Gene: Cyth3 (cytohesin 3) Rattus norvegicus
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Symbol: Cyth3
Name: cytohesin 3
Description: Predicted to have ARF guanyl-nucleotide exchange factor activity and phosphatidylinositol-3,4,5-trisphosphate binding activity. Predicted to be involved in Golgi vesicle transport; establishment of epithelial cell polarity; and positive regulation of cell adhesion. Predicted to localize to several cellular components, including the cytosol; extrinsic component of cytoplasmic side of plasma membrane; and nucleoplasm. Orthologous to human CYTH3 (cytohesin 3); PARTICIPATES IN phosphatidylinositol 3-kinase class I signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cytohesin-3; MGC124579; PH, SEC7 and coiled-coil domain-containing protein 3; pleckstrin homology, Sec7 and coiled-coil domains 3; pleckstrin homology, Sec7 and coiled/coil domains 3; Pscd3; rSec7-3; Sec7; SEC7 homolog C; Sec7C
Orthologs:
Homo sapiens (human) : CYTH3 (cytohesin 3)  HGNC  Alliance
Mus musculus (house mouse) : Cyth3 (cytohesin 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cyth3 (cytohesin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CYTH3 (cytohesin 3)
Canis lupus familiaris (dog) : CYTH3 (cytohesin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cyth3 (cytohesin 3)
Sus scrofa (pig) : CYTH3 (cytohesin 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01212,877,559 - 12,907,771 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01214,921,905 - 14,953,442 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,169,420 - 11,198,144 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11211,201,327 - 11,228,073 (-)NCBI
Celera1212,636,946 - 12,730,083 (-)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cyth3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620399
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-06-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.