Gene: Nos1 (nitric oxide synthase 1) Rattus norvegicus
Symbol: Nos1
Name: nitric oxide synthase 1
Description: ENCODES a protein that exhibits ATPase binding; cadmium ion binding; calmodulin binding; INVOLVED IN aging; arginine catabolic process; behavioral response to cocaine; PARTICIPATES IN arginine and proline metabolic pathway; arginine:glycine amidinotransferase deficiency pathway; guanidinoacetate methyltransferase deficiency pathway; ASSOCIATED WITH Brain Ischemia; Cardiomegaly; Cardiomyopathies; FOUND IN azurophil granule; cytoplasm; cytosol; INTERACTS WITH (+)-pilocarpine; (S)-colchicine; 17beta-estradiol
Type: protein-coding
Also known as: bNOS; constitutive NOS; N-NOS; NC-NOS; neuronal NOS; nitric oxidase synthase; nitric oxide synthase 1 (neuronal); nitric oxide synthase 1, neuronal; nitric oxide synthase, brain; nNOS; NOS type I; peptidyl-cysteine S-nitrosylase NOS1
Homo sapiens (human) : NOS1 (nitric oxide synthase 1)  HGNC  AGR
Mus musculus (house mouse) : Nos1 (nitric oxide synthase 1, neuronal)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Nos1 (nitric oxide synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NOS1 (nitric oxide synthase 1)
Canis lupus familiaris (dog) : NOS1 (nitric oxide synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nos1 (nitric oxide synthase 1)
more info ...
Allele / Splice: Nos1m1Mcwi  
Genetic Models: BN-Nos1m1Mcwi
Is Marker For: Strains:   SD  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01244,214,949 - 44,405,530 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01246,049,288 - 46,209,569 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41239,812,500 - 39,869,484 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11239,675,108 - 39,732,872 (-)NCBI
Celera1240,283,655 - 40,368,674 (-)NCBICelera
Cytogenetic Map12q16NCBI
RH 3.4 Map12718.8RGD
RH 3.4 Map12717.0RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Nos1
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3184
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-01-02
Status: ACTIVE