1-chloro-2,4-dinitrobenzene increases expression ISO RGD:732329 6480464 Dinitrochlorobenzene results in increased expression of ARG2 mRNA CTD PMID:16314067 1-fluoro-2,4-dinitrobenzene increases expression ISO RGD:732329 6480464 Dinitrofluorobenzene results in increased expression of ARG2 mRNA CTD PMID:23999411 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of ARG2 mRNA CTD PMID:16174780 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of ARG2 mRNA CTD PMID:12655037 more ... 17beta-estradiol increases expression ISO RGD:732329 6480464 Estradiol results in increased expression of ARG2 mRNA CTD PMID:20106945 17beta-estradiol increases expression ISO RGD:736823 6480464 Estradiol results in increased expression of ARG2 mRNA CTD PMID:19484750 17beta-estradiol multiple interactions ISO RGD:732329 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of ARG2 mRNA, [Estradiol co-treated with TGFB1 protein] results in decreased expression of ARG2 mRNA CTD PMID:20660070 , PMID:30165855 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO RGD:732329 6480464 AR mRNA affects the reaction [Metribolone results in increased expression of ARG2 protein], CXCL8 mRNA affects the reaction [Metribolone results in increased expression of ARG2 protein] CTD PMID:20711410 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO RGD:732329 6480464 Metribolone results in increased expression of ARG2 mRNA, Metribolone results in increased expression of ARG2 protein CTD PMID:20711410 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:732329 6480464 2 more ... CTD PMID:19095052 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:736823 6480464 Tetrachlorodibenzodioxin results in decreased expression of ARG2 mRNA CTD PMID:19465110 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:736823 6480464 Tetrachlorodibenzodioxin affects the expression of ARG2 mRNA CTD PMID:21570461 , PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:732329 6480464 Tetrachlorodibenzodioxin results in decreased expression of ARG2 mRNA CTD PMID:20106945 , PMID:21632981 2,4,6-trinitrobenzenesulfonic acid increases expression ISO RGD:736823 6480464 Trinitrobenzenesulfonic Acid results in increased expression of ARG2 mRNA CTD PMID:17982090 2-hydroxypropanoic acid decreases expression ISO RGD:732329 6480464 Lactic Acid results in decreased expression of ARG2 mRNA CTD PMID:30851411 4-(ethoxymethylene)-2-phenyloxazol-5-one increases expression ISO RGD:732329 6480464 Oxazolone results in increased expression of ARG2 mRNA CTD PMID:23999411 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of ARG2 mRNA CTD PMID:24780913 acrylamide decreases expression ISO RGD:736823 6480464 Acrylamide results in decreased expression of ARG2 mRNA CTD PMID:21319176 aflatoxin B1 affects expression ISO RGD:732329 6480464 Aflatoxin B1 affects the expression of ARG2 protein CTD PMID:20106945 aflatoxin B1 increases expression ISO RGD:732329 6480464 Aflatoxin B1 results in increased expression of ARG2 mRNA CTD PMID:21632981 , PMID:21641981 aflatoxin B1 increases expression ISO RGD:736823 6480464 Aflatoxin B1 results in increased expression of ARG2 mRNA CTD PMID:19770486 aldehydo-D-glucose increases expression ISO RGD:736823 6480464 Glucose results in increased expression of ARG2 mRNA CTD PMID:17178593 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of ARG2 mRNA CTD PMID:16483693 ampicillin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of ARG2 protein CTD PMID:30545405 arsane decreases expression ISO RGD:736823 6480464 Arsenic results in decreased expression of ARG2 mRNA CTD PMID:19654921 arsenic atom decreases expression ISO RGD:736823 6480464 Arsenic results in decreased expression of ARG2 mRNA CTD PMID:19654921 arsenite(3-) decreases expression ISO RGD:736823 6480464 arsenite results in decreased expression of ARG2 mRNA CTD PMID:18929588 arsenite(3-) multiple interactions ISO RGD:736823 6480464 TRP53 protein affects the reaction [arsenite results in decreased expression of ARG2 mRNA] CTD PMID:18929588 atrazine decreases expression ISO RGD:732329 6480464 Atrazine results in decreased expression of ARG2 mRNA CTD PMID:22378314 benzalkonium chloride increases expression ISO RGD:736823 6480464 Benzalkonium Compounds results in increased expression of ARG2 mRNA CTD PMID:30171875 benzo[a]pyrene increases expression ISO RGD:732329 6480464 Benzo(a)pyrene results in increased expression of ARG2 mRNA CTD PMID:21632981 , PMID:22316170 bicalutamide increases expression ISO RGD:732329 6480464 bicalutamide results in increased expression of ARG2 protein CTD PMID:20711410 bisphenol A affects expression ISO RGD:732329 6480464 bisphenol A affects the expression of ARG2 mRNA CTD PMID:20170705 , PMID:30903817 bisphenol A increases expression ISO RGD:732329 6480464 bisphenol A results in increased expression of ARG2 mRNA CTD PMID:27685785 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of ARG2 mRNA CTD PMID:25181051 bisphenol F decreases expression ISO RGD:736823 6480464 bisphenol F results in decreased expression of ARG2 mRNA CTD PMID:30951980 butanal increases expression ISO RGD:732329 6480464 butyraldehyde results in increased expression of ARG2 mRNA CTD PMID:26079696 C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of ARG2 mRNA CTD PMID:19167457 carbon nanotube increases expression ISO RGD:736823 6480464 Nanotubes, Carbon analog results in increased expression of ARG2 mRNA, Nanotubes, Carbon results in increased expression of ARG2 mRNA CTD PMID:25554681 chloroprene increases expression ISO RGD:736823 6480464 Chloroprene results in increased expression of ARG2 mRNA CTD PMID:23125180 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of ARG2 mRNA CTD PMID:22023808 cisplatin increases expression ISO RGD:732329 6480464 Cisplatin results in increased expression of ARG2 mRNA CTD PMID:27392435 cisplatin increases expression ISO RGD:736823 6480464 Cisplatin results in increased expression of ARG2 mRNA CTD PMID:25270620 copper atom decreases activity EXP 6480464 Copper results in decreased activity of ARG2 protein CTD PMID:11916150 copper atom increases expression EXP 6480464 Copper results in increased expression of ARG2 mRNA CTD PMID:30556269 copper(0) decreases activity EXP 6480464 Copper results in decreased activity of ARG2 protein CTD PMID:11916150 copper(0) increases expression EXP 6480464 Copper results in increased expression of ARG2 mRNA CTD PMID:30556269 copper(II) sulfate increases expression ISO RGD:732329 6480464 Copper Sulfate results in increased expression of ARG2 mRNA CTD PMID:19549813 cyclosporin A increases expression ISO RGD:732329 6480464 Cyclosporine results in increased expression of ARG2 mRNA CTD PMID:19159671 more ... cytarabine decreases expression ISO RGD:732329 6480464 Cytarabine results in decreased expression of ARG2 mRNA CTD PMID:21198554 D-glucose increases expression ISO RGD:736823 6480464 Glucose results in increased expression of ARG2 mRNA CTD PMID:17178593 dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of ARG2 mRNA CTD PMID:14618091 , PMID:20032058 dexamethasone multiple interactions EXP 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of ARG2 mRNA] CTD PMID:20032058 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of ARG2 mRNA CTD PMID:21266533 dicrotophos decreases expression ISO RGD:732329 6480464 dicrotophos results in decreased expression of ARG2 mRNA CTD PMID:28302478 dioxygen multiple interactions ISO RGD:732329 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of ARG2 protein] more ... CTD PMID:24951775 dioxygen multiple interactions ISO RGD:736823 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ARG2 mRNA CTD PMID:30529165 dioxygen increases expression ISO RGD:732329 6480464 Oxygen deficiency results in increased expression of ARG2 mRNA, Oxygen deficiency results in increased expression of ARG2 protein CTD PMID:20042640 more ... dorsomorphin multiple interactions ISO RGD:732329 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARG2 mRNA CTD PMID:27188386 doxorubicin increases expression ISO RGD:732329 6480464 Doxorubicin results in increased expression of ARG2 mRNA CTD PMID:29803840 doxorubicin decreases expression ISO RGD:732329 6480464 Doxorubicin results in decreased expression of ARG2 mRNA CTD PMID:28940058 elemental selenium decreases expression ISO RGD:732329 6480464 Selenium results in decreased expression of ARG2 mRNA CTD PMID:19244175 emodin decreases expression ISO RGD:736823 6480464 Emodin results in decreased expression of ARG2 mRNA CTD PMID:21319176 etoposide decreases expression ISO RGD:732329 6480464 Etoposide results in decreased expression of ARG2 mRNA CTD PMID:29397400 folic acid multiple interactions ISO RGD:732329 6480464 [Folic Acid deficiency co-treated with Methotrexate] results in increased expression of ARG2 mRNA CTD PMID:24657277 formaldehyde increases expression ISO RGD:732329 6480464 Formaldehyde results in increased expression of ARG2 mRNA CTD PMID:27664576 furan increases expression EXP 6480464 furan results in increased expression of ARG2 mRNA CTD PMID:27387713 gentamycin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of ARG2 protein CTD PMID:30545405 glucose increases expression ISO RGD:736823 6480464 Glucose results in increased expression of ARG2 mRNA CTD PMID:17178593 glycidol increases expression EXP 6480464 glycidol results in increased expression of ARG2 mRNA CTD PMID:24915197 GW 4064 decreases expression ISO RGD:736823 6480464 GW 4064 results in decreased expression of ARG2 mRNA CTD PMID:26655953 hydrogen peroxide affects expression ISO RGD:732329 6480464 Hydrogen Peroxide affects the expression of ARG2 mRNA CTD PMID:23410634 hydroquinone increases expression ISO RGD:732329 6480464 hydroquinone results in increased expression of ARG2 mRNA CTD PMID:31256213 irinotecan affects expression EXP 6480464 Irinotecan affects the expression of ARG2 mRNA CTD PMID:20097248 isoflavones decreases expression ISO RGD:732329 6480464 Isoflavones results in decreased expression of ARG2 mRNA CTD PMID:17374662 isotretinoin decreases expression ISO RGD:732329 6480464 Isotretinoin results in decreased expression of ARG2 mRNA CTD PMID:20436886 lithium atom multiple interactions EXP 6480464 Lithium inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA] CTD PMID:19149911 lithium hydride multiple interactions EXP 6480464 Lithium inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA] CTD PMID:19149911 LY294002 multiple interactions ISO RGD:732329 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of ARG2 protein] CTD PMID:24951775 menadione affects expression ISO RGD:732329 6480464 Vitamin K 3 affects the expression of ARG2 mRNA CTD PMID:23410634 mercury atom decreases activity EXP 6480464 Mercury results in decreased activity of ARG2 protein CTD PMID:11916150 mercury dichloride decreases response to substance ISO RGD:732329 6480464 ARG2 protein results in decreased susceptibility to Mercuric Chloride CTD PMID:17874066 mercury dichloride multiple interactions EXP 6480464 Mercuric Chloride results in decreased expression of and results in decreased activity of ARG2 protein CTD PMID:17874066 mercury(0) decreases activity EXP 6480464 Mercury results in decreased activity of ARG2 protein CTD PMID:11916150 methamphetamine multiple interactions EXP 6480464 Lithium inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA], Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA] CTD PMID:19149911 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of ARG2 mRNA CTD PMID:19149911 methotrexate multiple interactions ISO RGD:732329 6480464 [Folic Acid deficiency co-treated with Methotrexate] results in increased expression of ARG2 mRNA CTD PMID:24657277 methotrexate increases expression ISO RGD:732329 6480464 Methotrexate results in increased expression of ARG2 mRNA CTD PMID:24657277 methylmercury chloride increases expression ISO RGD:736823 6480464 methylmercuric chloride results in increased expression of ARG2 mRNA CTD PMID:20061341 metronidazole multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of ARG2 protein CTD PMID:30545405 N-methyl-4-phenylpyridinium increases expression ISO RGD:732329 6480464 1-Methyl-4-phenylpyridinium results in increased expression of ARG2 mRNA CTD PMID:24810058 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of ARG2 mRNA CTD PMID:28801915 N-nitrosodiethylamine multiple interactions ISO RGD:736823 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ARG2 mRNA CTD PMID:24535843 naphthalene increases expression ISO RGD:736823 6480464 naphthalene results in increased expression of ARG2 mRNA CTD PMID:18978301 neomycin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of ARG2 protein CTD PMID:30545405 nickel sulfate increases expression ISO RGD:732329 6480464 nickel sulfate results in increased expression of ARG2 mRNA CTD PMID:16314067 organophosphorus compound increases expression ISO RGD:732329 6480464 Organophosphorus Compounds results in increased expression of ARG2 protein CTD PMID:23557688 ozone multiple interactions ISO RGD:736823 6480464 TTPA protein affects the reaction [Ozone results in increased expression of ARG2 mRNA] CTD PMID:19555225 ozone increases expression ISO RGD:736823 6480464 Ozone results in increased expression of ARG2 mRNA CTD PMID:17095637 paracetamol affects expression ISO RGD:736823 6480464 Acetaminophen affects the expression of ARG2 mRNA CTD PMID:17562736 paracetamol affects expression ISO RGD:732329 6480464 Acetaminophen affects the expression of ARG2 mRNA CTD PMID:25704631 paracetamol increases expression ISO RGD:732329 6480464 Acetaminophen results in increased expression of ARG2 mRNA CTD PMID:21420995 more ... paraquat increases expression EXP 6480464 Paraquat results in increased expression of ARG2 mRNA CTD PMID:16854511 , PMID:20388547 perfluorooctanoic acid increases expression ISO RGD:732329 6480464 perfluorooctanoic acid results in increased expression of ARG2 mRNA, perfluorooctanoic acid results in increased expression of ARG2 protein CTD PMID:23978341 , PMID:26879310 phenobarbital multiple interactions ISO RGD:736823 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ARG2 mRNA CTD PMID:24535843 phenobarbital affects expression ISO RGD:732329 6480464 Phenobarbital affects the expression of ARG2 mRNA CTD PMID:19159669 phosgene affects expression ISO RGD:736823 6480464 Phosgene affects the expression of ARG2 mRNA CTD PMID:16300373 pravastatin increases expression ISO RGD:736823 6480464 Pravastatin results in increased expression of ARG2 mRNA CTD PMID:27225895 progesterone multiple interactions ISO RGD:732329 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of ARG2 mRNA CTD PMID:20660070 progesterone decreases expression ISO RGD:736823 6480464 Progesterone results in decreased expression of ARG2 mRNA CTD PMID:22238285 propanal increases expression ISO RGD:732329 6480464 propionaldehyde results in increased expression of ARG2 mRNA CTD PMID:26079696 propiconazole increases expression ISO RGD:736823 6480464 propiconazole results in increased expression of ARG2 mRNA CTD PMID:21278054 quercetin increases expression ISO RGD:732329 6480464 Quercetin results in increased expression of ARG2 mRNA CTD PMID:21632981 quinolin-8-ol increases expression ISO RGD:732329 6480464 Oxyquinoline results in increased expression of ARG2 mRNA CTD PMID:21632981 rac-lactic acid decreases expression ISO RGD:732329 6480464 Lactic Acid results in decreased expression of ARG2 mRNA CTD PMID:30851411 raloxifene increases expression ISO RGD:736823 6480464 Raloxifene Hydrochloride results in increased expression of ARG2 mRNA CTD PMID:22841776 resveratrol multiple interactions ISO RGD:732329 6480464 resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of ARG2 mRNA], resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of ARG2 protein] CTD PMID:24951775 SB 203580 multiple interactions ISO RGD:736823 6480464 SB 203580 inhibits the reaction [AGT protein modified form results in increased expression of ARG2 protein] CTD PMID:21289285 SB 431542 multiple interactions ISO RGD:732329 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARG2 mRNA CTD PMID:27188386 scopolamine decreases expression EXP 6480464 Scopolamine results in decreased expression of ARG2 mRNA CTD PMID:12818353 selenium atom decreases expression ISO RGD:732329 6480464 Selenium results in decreased expression of ARG2 mRNA CTD PMID:19244175 silicon dioxide decreases expression ISO RGD:732329 6480464 Silicon Dioxide analog results in decreased expression of ARG2 mRNA CTD PMID:25895662 silicon dioxide increases expression ISO RGD:736823 6480464 Silicon Dioxide results in increased expression of ARG2 mRNA CTD PMID:23221170 , PMID:29203145 sodium arsenite increases expression ISO RGD:736823 6480464 sodium arsenite results in increased expression of ARG2 mRNA CTD PMID:18812580 sodium arsenite affects methylation ISO RGD:732329 6480464 sodium arsenite affects the methylation of ARG2 gene CTD PMID:28589171 sodium fluoride increases expression ISO RGD:736823 6480464 Sodium Fluoride results in increased expression of ARG2 protein CTD PMID:28918527 sodium fluoride decreases expression ISO RGD:736823 6480464 Sodium Fluoride results in decreased expression of ARG2 mRNA CTD PMID:27862939 Soman decreases expression EXP 6480464 Soman results in decreased expression of ARG2 mRNA CTD PMID:19281266 succimer multiple interactions ISO RGD:736823 6480464 [Succimer binds to Magnetite Nanoparticles] which results in increased expression of ARG2 mRNA, [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of ARG2 mRNA CTD PMID:21641980 , PMID:26378955 succimer multiple interactions ISO RGD:732329 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of ARG2 mRNA CTD PMID:26378955 tamoxifen increases expression ISO RGD:736823 6480464 Tamoxifen results in increased expression of ARG2 mRNA CTD PMID:22841776 tert-butyl hydroperoxide affects expression ISO RGD:732329 6480464 tert-Butylhydroperoxide affects the expression of ARG2 mRNA CTD PMID:23410634 testosterone multiple interactions EXP 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of ARG2 mRNA] CTD PMID:20032058 thapsigargin decreases expression ISO RGD:732329 6480464 Thapsigargin results in decreased expression of ARG2 mRNA CTD PMID:22378314 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of ARG2 mRNA CTD PMID:23411599 titanium dioxide increases expression ISO RGD:736823 6480464 titanium dioxide results in increased expression of ARG2 mRNA CTD PMID:23557971 , PMID:27760801 torcetrapib increases expression ISO RGD:732329 6480464 torcetrapib results in increased expression of ARG2 mRNA CTD PMID:23228038 trichostatin A decreases expression ISO RGD:732329 6480464 trichostatin A results in decreased expression of ARG2 mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A increases expression ISO RGD:732329 6480464 trichostatin A results in increased expression of ARG2 mRNA CTD PMID:28542535 trichostatin A multiple interactions ISO RGD:732329 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARG2 mRNA CTD PMID:27188386 trimellitic anhydride increases expression ISO RGD:736823 6480464 trimellitic anhydride results in increased expression of ARG2 mRNA CTD PMID:16141432 , PMID:19042947 tunicamycin decreases expression ISO RGD:732329 6480464 Tunicamycin results in decreased expression of ARG2 mRNA CTD PMID:22378314 urea increases chemical synthesis ISO RGD:732329 6480464 ARG2 protein results in increased chemical synthesis of Urea CTD PMID:17680661 valproic acid affects expression ISO RGD:736823 6480464 Valproic Acid affects the expression of ARG2 mRNA CTD PMID:17963808 valproic acid decreases expression ISO RGD:732329 6480464 Valproic Acid results in decreased expression of ARG2 protein CTD PMID:29501571 valproic acid affects expression ISO RGD:732329 6480464 Valproic Acid affects the expression of ARG2 mRNA CTD PMID:25979313 valproic acid increases expression ISO RGD:732329 6480464 Valproic Acid results in increased expression of ARG2 mRNA CTD PMID:23179753 more ... valproic acid multiple interactions EXP 6480464 Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA] CTD PMID:19149911 vancomycin decreases expression ISO RGD:736823 6480464 Vancomycin results in decreased expression of ARG2 mRNA CTD PMID:18930951 vancomycin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of ARG2 protein CTD PMID:30545405 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of ARG2 mRNA CTD PMID:19015723 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of ARG2 mRNA CTD PMID:30207508 zaragozic acid A increases expression ISO RGD:736823 6480464 squalestatin 1 results in increased expression of ARG2 mRNA CTD PMID:27225895 zaragozic acid A decreases expression EXP 6480464 squalestatin 1 results in decreased expression of ARG2 mRNA CTD PMID:27225895 zinc atom decreases expression EXP 6480464 Zinc deficiency results in decreased expression of ARG2 mRNA CTD PMID:11717422 zinc dichloride increases expression ISO RGD:732329 6480464 zinc chloride results in increased expression of ARG2 mRNA CTD PMID:18947441 zinc(0) decreases expression EXP 6480464 Zinc deficiency results in decreased expression of ARG2 mRNA CTD PMID:11717422
Biological Process adaptive immune response IEA UniProtKB-KW:KW-1064 1600115 GO_REF:0000037 UniProt GO_REF:0000037 apoptotic process IEP 4143285 RGD arginine catabolic process to ornithine TAS 1358311 RGD arginine catabolic process to ornithine IBA PANTHER:PTN000144386 more ... 13792537 PMID:21873635 GO_Central arginine catabolic process to ornithine IDA 8693655 RGD arginine metabolic process IMP 1582129 RGD arginine metabolic process IEA UniProtKB-KW:KW-0056 1600115 GO_REF:0000038 UniProt GO_REF:0000038 cellular response to dexamethasone stimulus IEP 4144048 RGD cellular response to interferon-gamma IEP 4144048 RGD cellular response to interleukin-4 IEP 4144042 and interleukin-13 RGD cellular response to lipopolysaccharide IEP 4144048 RGD lung development IEP 4143284 RGD maternal process involved in female pregnancy IEP 4143426 RGD midgut development IEP 4144052 RGD negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process ISO RGD:736823 1624291 (MGI:MGI:5908764, PMID:27745970) RGD MGI:MGI:5908764 , PMID:27745970 negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process IEA UniProtKB:O08691 , ensembl:ENSMUSP000000215501600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of CD4-positive, alpha-beta T cell proliferation ISO RGD:736823 1624291 (MGI:MGI:5908533, PMID:25009204) RGD MGI:MGI:5908533 , PMID:25009204 negative regulation of CD4-positive, alpha-beta T cell proliferation IEA UniProtKB:O08691 , ensembl:ENSMUSP000000215501600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of chemokine (C-C motif) ligand 4 production ISO RGD:736823 1624291 (MGI:MGI:5908771, PMID:27074721) RGD MGI:MGI:5908771 , PMID:27074721 negative regulation of chemokine (C-C motif) ligand 4 production IEA UniProtKB:O08691 , ensembl:ENSMUSP000000215501600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of chemokine (C-C motif) ligand 5 production ISO RGD:736823 1624291 (MGI:MGI:5908771, PMID:27074721) RGD MGI:MGI:5908771 , PMID:27074721 negative regulation of chemokine (C-C motif) ligand 5 production IEA UniProtKB:O08691 , ensembl:ENSMUSP000000215501600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of defense response to bacterium ISO RGD:736823 1624291 (MGI:MGI:5908771, PMID:27074721) RGD MGI:MGI:5908771 , PMID:27074721 negative regulation of defense response to bacterium IEA UniProtKB:O08691 , ensembl:ENSMUSP000000215501600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of interleukin-13 secretion ISO RGD:736823 1624291 (MGI:MGI:5810834, PMID:27214549) RGD MGI:MGI:5810834 , PMID:27214549 negative regulation of interleukin-13 secretion IEA UniProtKB:O08691 , ensembl:ENSMUSP000000215501600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of interleukin-17 secretion ISO RGD:736823 1624291 (MGI:MGI:5810834, PMID:27214549) RGD MGI:MGI:5810834 , PMID:27214549 negative regulation of interleukin-17 secretion IEA UniProtKB:O08691 , ensembl:ENSMUSP000000215501600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of macrophage inflammatory protein 1 alpha production ISO RGD:736823 1624291 (MGI:MGI:5908771, PMID:27074721) RGD MGI:MGI:5908771 , PMID:27074721 negative regulation of macrophage inflammatory protein 1 alpha production IEA UniProtKB:O08691 , ensembl:ENSMUSP000000215501600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of nitric-oxide synthase activity IMP 1582129 RGD negative regulation of striated muscle contraction IMP 1582129 RGD negative regulation of tumor necrosis factor production ISO RGD:732329 1624291 (PMID:28614294) RGD PMID:28614294 negative regulation of tumor necrosis factor secretion ISO RGD:736823 1624291 (MGI:MGI:5908771, PMID:27074721) RGD MGI:MGI:5908771 , PMID:27074721 negative regulation of tumor necrosis factor secretion IEA UniProtKB:O08691 , ensembl:ENSMUSP000000215501600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of type 2 immune response ISO RGD:736823 1624291 (MGI:MGI:5810834, PMID:27214549) RGD MGI:MGI:5810834 , PMID:27214549 negative regulation of type 2 immune response IEA UniProtKB:O08691 , ensembl:ENSMUSP000000215501600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of cellular senescence ISO RGD:732329 1624291 (PMID:22928666) RGD PMID:22928666 positive regulation of cellular senescence IEA UniProtKB:P78540 , ensembl:ENSP000002617831600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of interleukin-1 beta secretion ISO RGD:736823 1624291 (MGI:MGI:5908771, PMID:27074721) RGD MGI:MGI:5908771 , PMID:27074721 regulation of interleukin-1 beta secretion IEA UniProtKB:O08691 , ensembl:ENSMUSP000000215501600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of L-arginine import IDA 4144049 RGD regulation of nitric oxide biosynthetic process IEP 634667 RGD regulation of reactive oxygen species biosynthetic process ISO RGD:736823 1624291 (MGI:MGI:5810834, PMID:27214549) RGD MGI:MGI:5810834 , PMID:27214549 regulation of reactive oxygen species biosynthetic process IEA UniProtKB:O08691 , ensembl:ENSMUSP000000215501600115 GO_REF:0000107 Ensembl GO_REF:0000107 response to amine IEP 4110830 spermine RGD response to amino acid IEP 4143261 N-acetylcysteine RGD response to axon injury IEP 4143237 unilateral vestibular deafferentation RGD response to cadmium ion IEP 4143188 RGD response to drug IEP 4143232 pirfenidone RGD response to glucose IEP 4143262 RGD response to herbicide IEP 2317876 paraquat RGD response to hormone IEP 4144043 arginine vasopressin RGD response to hypoxia IEP 4143278 RGD response to mercury ion IEP 4143285 RGD response to nutrient IEP 4143283 flavanol-containing dietary RGD response to selenium ion IEP 4143267 RGD response to vitamin E IEP 4143267 RGD striated muscle contraction ISO RGD:736823 1624291 (MGI:MGI:3621611, PMID:16537391) RGD MGI:MGI:3621611 , PMID:16537391 striated muscle contraction IEA UniProtKB:O08691 , ensembl:ENSMUSP000000215501600115 GO_REF:0000107 Ensembl GO_REF:0000107 urea cycle IEA UniPathway:UPA00158 1600115 GO_REF:0000041 UniProt GO_REF:0000041 ureteric bud development IEA UniProtKB:O08691 , ensembl:ENSMUSP000000215501600115 GO_REF:0000107 Ensembl GO_REF:0000107 ureteric bud development ISO RGD:736823 1624291 (PMID:16545622) RGD PMID:16545622 Cellular Component cytoplasm IBA MGI:MGI:1330806 more ... 13792537 PMID:21873635 GO_Central cytoplasm IBA PANTHER:PTN000144386 , RGD:2150 13792537 PMID:21873635 GO_Central mitochondrion IDA 1358311 ; 1582129 RGD mitochondrion IBA MGI:MGI:1330806 more ... 13792537 PMID:21873635 GO_Central mitochondrion ISO RGD:736823 1624291 (MGI:MGI:5908533, PMID:25009204) RGD MGI:MGI:5908533 , PMID:25009204 mitochondrion IEA UniProtKB:O08691 , ensembl:ENSMUSP000000215501600115 GO_REF:0000107 Ensembl GO_REF:0000107 Molecular Function arginase activity IDA 634667 ; 1582129 RGD arginase activity ISO RGD:732329 1624291 (PMID:16128822) RGD PMID:16128822 arginase activity IEA EC:3.5.3.1 1600115 GO_REF:0000003 UniProt GO_REF:0000003 manganese ion binding IBA PANTHER:PTN000144386 more ... 13792537 PMID:21873635 GO_Central metal ion binding IEA UniProtKB-KW:KW-0479 1600115 GO_REF:0000038 UniProt GO_REF:0000038 nitric-oxide synthase binding IPI RGD:3184 1582129 RGD protein binding IPI RGD:3184 1582129 RGD protein binding IPI UniProtKB:P29476 1582129 PMID:16537391 IntAct
Gene-Chemical Interaction Annotations
