Uae7 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Uae7 (Urinary albumin excretion QTL 7) Rattus norvegicus

Symbol: Uae7
Name: Urinary albumin excretion QTL 7
RGD ID: 724536
Trait: urine albumin amount   (VT:0002871)    
Measurement Type: urine albumin level   (CMO:0000130)    
LOD Score: 3.5
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8693,560,258 - 136,550,638RGD_MAPPER_PIPELINE
mRatBN7.2672,202,632 - 130,729,475RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0675,623,277 - 136,143,011RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0685,163,175 - 144,273,990RGDRnor5.0
RGSC_v3.4675,049,527 - 136,452,267RGDRGSC3.4
RGSC_v3.1675,052,653 - 136,458,454RGD
Cross Type: intercross
Strains Crossed: SS/JrTol SHR/NHsd 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uae7RatAlbuminuria  QTM 634617 RGD 
Uae7Ratproteinuria  QTM 634617 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uae7Ratalbuminuria  IDA 634617 RGD 
Uae7Ratincreased urine protein level  IDA 634617 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uae7Raturine albumin level  IDA 634617 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uae7Ratcontrolled sodium content diet  IDA 634617 RGD 
Uae7Ratfasting  IDA 634617 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uae7Raturine analysis  IDA 634617 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uae7RatSHR/NHsd  IEA 634617 RGD 
Uae7RatSS/JrTol  IEA 634617 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uae7Raturine albumin amount  IDA 634617 RGD 


#
Reference Title
Reference Citation
1. Time-course genetic analysis of albuminuria in Dahl salt-sensitive rats on low-salt diet. Garrett MR, etal., J Am Soc Nephrol 2003 May;14(5):1175-87.


1 to 20 of 903 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
41303109LOC120093206uncharacterized LOC12009320667220087072202818Rat
41114950LOC120093357U1 spliceosomal RNA67220306672203228Rat
41074541LOC120093346U1 spliceosomal RNA67220576072205923Rat
41245801LOC120093302U1 spliceosomal RNA67221144572211608Rat
41140941LOC120093313U1 spliceosomal RNA67221868472218847Rat
41319468LOC120093324U1 spliceosomal RNA67222436972224532Rat
41367672LOC120093335U1 spliceosomal RNA67222704472227207Rat
7561334LOC102548522uncharacterized LOC10254852267222721772231374Rat
1304647Snx6sorting nexin 667223095072274157Rat
7646365LOC102548461uncharacterized LOC10254846167227414272290681Rat
40971021LOC120093210uncharacterized LOC12009321067230649372316083Rat
9167354LOC103695296glyceraldehyde-3-phosphate dehydrogenase pseudogene67232884872329825Rat
1306982Cfl2cofilin 267235566472359709Rat
1306199Baz1abromodomain adjacent to zinc finger domain, 1A67238970172512516Rat
11491526LOC108351236uncharacterized LOC10835123667249434372522266Rat
41278108LOC120093303U6 spliceosomal RNA67249442772494534Rat
13046242700097O09RiklRIKEN cDNA 2700097009 gene like67254216672587511Rat
621390Srp54asignal recognition particle 54A67258758472626878Rat
2323636Fam177a1family with sequence similarity 177, member A167263262872647553Rat
1309207Ppp2r3cprotein phosphatase 2, regulatory subunit B'', gamma67264702572670885Rat

1 to 20 of 903 rows
1 to 20 of 1119 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
11241D6Mit311767220263272202749Ratregion
11242D6Arb1738967220263372203021Ratregion
11242D6Arb1738967222725172227640Ratregion
11241D6Mit311767222752472227641Ratregion
5025686RH12926819067222988872230078Ratregion
5043206RH12989319267223112372231315Ratregion
44102D6Got8620667228099372281199Ratregion
5049900RH13374620267230633372306370Ratregion
5032525D14S131917067235570772355877Ratregion
5039402RH12768518867238997572390163Ratregion
5042688RH12958516767248061572480782Ratregion
5084002AI0109229067248476672484856Ratregion
42326D6Rat22023167253822172538452Ratregion
5071700RH13523415367254527472545427Ratregion
35140D6Rat228967259359672593685Ratregion
1633389D6Got31122867260463272604860Ratregion
5041226RH12873518267262496772625149Ratregion
5056529RH14443125567262655072626805Ratregion
5029041RH14329010167263265572632756Ratregion
5081807BE11838815367263289672633049Ratregion
1 to 20 of 1119 rows

Flank 1: (D6Mit3)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2672,202,632 - 72,202,749 (-)MAPPER
mRatBN7.2672,227,524 - 72,227,641 (+)MAPPER
Rnor_6.0675,623,277 - 75,623,393NCBI
Rnor_5.0685,163,175 - 85,163,291UniSTS
RGSC_v3.4675,049,527 - 75,049,644RGD
RGSC_v3.4675,049,528 - 75,049,644UniSTS
RGSC_v3.1675,052,653 - 75,052,770RGD
Celera671,073,450 - 71,073,566UniSTS
RH 2.0 Map6677.4RGD
Peak: (D6Uia5)
Rat AssemblyChrPosition (strand)Source
GRCr86115,055,369 - 115,055,528 (+)Marker Load Pipeline
mRatBN7.26109,324,553 - 109,324,712 (+)MAPPER
Rnor_6.06114,127,227 - 114,127,385NCBI
Rnor_5.06123,397,400 - 123,397,558UniSTS
RGSC_v3.46113,959,390 - 113,959,549RGD
RGSC_v3.46113,959,391 - 113,959,549UniSTS
RGSC_v3.16113,962,921 - 113,963,080RGD
Celera6107,095,788 - 107,095,946UniSTS
Cytogenetic Map6 RGD
Flank 2: (D6Wox13)
Rat AssemblyChrPosition (strand)Source
GRCr86136,550,368 - 136,550,638 (+)Marker Load Pipeline
mRatBN7.26130,729,205 - 130,729,475 (+)MAPPER
Rnor_6.06136,142,742 - 136,143,011NCBI
Rnor_5.06144,273,721 - 144,273,990UniSTS
RGSC_v3.46136,451,997 - 136,452,267RGD
RGSC_v3.46136,451,998 - 136,452,267UniSTS
RGSC_v3.16136,458,184 - 136,458,454RGD
Celera6128,284,545 - 128,284,814UniSTS
RH 2.0 Map20692.9RGD
Cytogenetic Map6q32UniSTS


1 to 10 of 58 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6122549046140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)6122549046137801795Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat

1 to 10 of 58 rows


Database
Acc Id
Source(s)
NCBI Gene Uae7

Note Type Note Reference
qtl_cross_type intercross  
qtl_general SS allele associated with reduced urinary albumin excretion, highest at early stage of 8 weeks of age and the association weakened with age 634617
qtl_general at older age SS allele linked to decreased urinary protein excretion (UPE) (LOD = 5.0) 634617