Dact1 (dishevelled-binding antagonist of beta-catenin 1) - Rat Genome Database

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Gene: Dact1 (dishevelled-binding antagonist of beta-catenin 1) Rattus norvegicus
Analyze
Symbol: Dact1
Name: dishevelled-binding antagonist of beta-catenin 1
RGD ID: 1564008
Description: Predicted to enable several functions, including beta-catenin binding activity; delta-catenin binding activity; and enzyme binding activity. Predicted to be involved in several processes, including negative regulation of JNK cascade; negative regulation of beta-catenin-TCF complex assembly; and regulation of Wnt signaling pathway. Predicted to act upstream of or within several processes, including dendrite morphogenesis; positive regulation of fat cell differentiation; and positive regulation of protein catabolic process. Predicted to be located in nucleoplasm. Predicted to be part of beta-catenin destruction complex. Predicted to be active in cytoplasm; glutamatergic synapse; and postsynapse. Human ortholog(s) of this gene implicated in Townes-Brocks syndrome. Orthologous to human DACT1 (dishevelled binding antagonist of beta catenin 1); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: dapper homolog 1; dapper homolog 1, antagonist of beta-catenin; dapper homolog 1, antagonist of beta-catenin (xenopus); dapper, antagonist of beta-catenin, homolog 1; dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis); LOC500666; RGD1564008; similar to dapper 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2689,790,676 - 89,818,254 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl689,790,644 - 89,817,906 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx690,174,745 - 90,185,345 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0690,474,205 - 90,484,805 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0689,913,716 - 89,924,316 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0693,740,440 - 93,751,003 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl693,740,586 - 93,749,809 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06103,201,826 - 103,212,384 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4693,402,304 - 93,411,668 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera688,272,055 - 88,282,541 (+)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP)
1,2-dichloroethane  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
amiodarone  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
calciol  (ISO)
cantharidin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
choline  (ISO)
cisplatin  (ISO)
clothianidin  (ISO)
cobalt dichloride  (EXP)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
diquat  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
flusilazole  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
hydrogen cyanide  (ISO)
indometacin  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium cyanide  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
raloxifene  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
thioacetamide  (EXP)
titanium dioxide  (EXP)
toluene 2,4-diisocyanate  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15580286   PMID:16446366   PMID:17197390   PMID:18936100   PMID:19073771   PMID:19701191   PMID:20145239   PMID:20335472   PMID:21262972   PMID:21718540   PMID:22470507   PMID:22610794  
PMID:24879894   PMID:25825496   PMID:27714812   PMID:35802196  


Genomics

Comparative Map Data
Dact1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2689,790,676 - 89,818,254 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl689,790,644 - 89,817,906 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx690,174,745 - 90,185,345 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0690,474,205 - 90,484,805 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0689,913,716 - 89,924,316 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0693,740,440 - 93,751,003 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl693,740,586 - 93,749,809 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06103,201,826 - 103,212,384 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4693,402,304 - 93,411,668 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera688,272,055 - 88,282,541 (+)NCBICelera
Cytogenetic Map6q24NCBI
DACT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381458,634,061 - 58,648,321 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1458,633,967 - 58,648,321 (+)EnsemblGRCh38hg38GRCh38
GRCh371459,100,779 - 59,115,039 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361458,174,510 - 58,184,792 (+)NCBINCBI36Build 36hg18NCBI36
Build 341458,174,611 - 58,184,789NCBI
Celera1439,154,745 - 39,165,027 (+)NCBICelera
Cytogenetic Map14q23.1NCBI
HuRef1439,264,994 - 39,279,247 (+)NCBIHuRef
CHM1_11459,039,260 - 59,053,513 (+)NCBICHM1_1
T2T-CHM13v2.01452,841,138 - 52,855,396 (+)NCBIT2T-CHM13v2.0
Dact1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391271,356,658 - 71,366,881 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1271,356,658 - 71,366,881 (+)EnsemblGRCm39 Ensembl
GRCm381271,309,884 - 71,320,107 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1271,309,884 - 71,320,107 (+)EnsemblGRCm38mm10GRCm38
MGSCv371272,410,871 - 72,421,094 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361272,228,589 - 72,237,499 (+)NCBIMGSCv36mm8
Celera1272,410,534 - 72,420,756 (+)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1229.39NCBI
Dact1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546612,367,775 - 12,373,036 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546612,367,760 - 12,374,141 (+)NCBIChiLan1.0ChiLan1.0
DACT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11458,978,423 - 58,988,860 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01439,231,910 - 39,242,353 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11457,498,901 - 57,510,019 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1457,499,906 - 57,510,019 (+)Ensemblpanpan1.1panPan2
DACT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1833,950,016 - 33,959,671 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl833,949,926 - 33,958,449 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha833,710,858 - 33,719,128 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0834,191,432 - 34,199,711 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl834,191,432 - 34,199,675 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1833,803,264 - 33,811,542 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0833,871,726 - 33,879,997 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0834,246,058 - 34,254,343 (+)NCBIUU_Cfam_GSD_1.0
Dact1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864071,165,976 - 71,174,693 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364953,017,150 - 3,025,684 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364953,017,029 - 3,026,759 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DACT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1187,719,290 - 187,729,422 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11187,719,391 - 187,729,568 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DACT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12435,821,518 - 35,832,486 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2435,821,990 - 35,832,712 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605324,088,036 - 24,098,815 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dact1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248843,739,334 - 3,948,621 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248843,733,648 - 3,750,207 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dact1
176 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:107
Count of miRNA genes:88
Interacting mature miRNAs:96
Transcripts:ENSRNOT00000011466
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)65672856290198260Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)683190345106747639Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat

Markers in Region
RH135896  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2689,800,961 - 89,801,144 (+)MAPPERmRatBN7.2
Rnor_6.0693,750,637 - 93,750,819NCBIRnor6.0
Rnor_5.06103,212,018 - 103,212,200UniSTSRnor5.0
RGSC_v3.4693,412,445 - 93,412,627UniSTSRGSC3.4
Celera688,282,175 - 88,282,357UniSTS
Cytogenetic Map6q24UniSTS
UniSTS:498289  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2689,794,805 - 89,794,871 (+)MAPPERmRatBN7.2
Rnor_6.0693,744,571 - 93,744,636NCBIRnor6.0
Rnor_6.0693,738,191 - 93,738,256NCBIRnor6.0
Rnor_5.06103,199,572 - 103,199,637UniSTSRnor5.0
Rnor_5.06103,205,952 - 103,206,017UniSTSRnor5.0
RGSC_v3.4693,406,289 - 93,406,354UniSTSRGSC3.4
Celera688,276,186 - 88,276,251UniSTS
Cytogenetic Map6q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 26 13 6 1 6 53 19 30 5
Low 3 17 36 27 18 27 8 11 21 16 11 6 8
Below cutoff 8 8 8

Sequence


RefSeq Acc Id: ENSRNOT00000011466   ⟹   ENSRNOP00000011466
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl689,790,644 - 89,817,906 (+)Ensembl
Rnor_6.0 Ensembl693,740,586 - 93,749,809 (+)Ensembl
RefSeq Acc Id: NM_001399171   ⟹   NP_001386100
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2689,790,722 - 89,801,328 (+)NCBI
RefSeq Acc Id: XM_039113237   ⟹   XP_038969165
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2689,790,676 - 89,818,106 (+)NCBI
RefSeq Acc Id: XM_039113239   ⟹   XP_038969167
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2689,790,676 - 89,803,250 (+)NCBI
RefSeq Acc Id: XM_039113240   ⟹   XP_038969168
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2689,790,676 - 89,818,109 (+)NCBI
RefSeq Acc Id: XM_039113241   ⟹   XP_038969169
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2689,790,676 - 89,803,250 (+)NCBI
RefSeq Acc Id: XM_576044   ⟹   XP_576044
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2689,790,676 - 89,801,328 (+)NCBI
Rnor_6.0693,740,440 - 93,751,003 (+)NCBI
Rnor_5.06103,201,826 - 103,212,384 (+)NCBI
RGSC_v3.4693,402,304 - 93,411,668 (+)RGD
Sequence:
RefSeq Acc Id: XR_005506012
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2689,790,676 - 89,818,251 (+)NCBI
RefSeq Acc Id: XR_005506013
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2689,790,676 - 89,818,254 (+)NCBI
RefSeq Acc Id: XR_005506014
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2689,790,676 - 89,818,252 (+)NCBI
RefSeq Acc Id: XP_576044   ⟸   XM_576044
- Peptide Label: isoform X1
- UniProtKB: D4A3W8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000011466   ⟸   ENSRNOT00000011466
RefSeq Acc Id: XP_038969168   ⟸   XM_039113240
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038969165   ⟸   XM_039113237
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038969167   ⟸   XM_039113239
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038969169   ⟸   XM_039113241
- Peptide Label: isoform X6
RefSeq Acc Id: NP_001386100   ⟸   NM_001399171
- UniProtKB: D4A3W8 (UniProtKB/TrEMBL),   A6HC19 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A3W8-F1-model_v2 AlphaFold D4A3W8 1-815 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694656
Promoter ID:EPDNEW_R5174
Type:multiple initiation site
Name:Dact1_1
Description:dishevelled-binding antagonist of beta-catenin 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0693,740,497 - 93,740,557EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564008 AgrOrtholog
BioCyc Gene G2FUF-37181 BioCyc
Ensembl Genes ENSRNOG00000008445 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011466 ENTREZGENE
  ENSRNOT00000011466.4 UniProtKB/TrEMBL
InterPro Dapper UniProtKB/TrEMBL
KEGG Report rno:500666 UniProtKB/TrEMBL
NCBI Gene 500666 ENTREZGENE
PANTHER PTHR15919 UniProtKB/TrEMBL
  PTHR15919:SF12 UniProtKB/TrEMBL
Pfam Dapper UniProtKB/TrEMBL
PhenoGen Dact1 PhenoGen
RatGTEx ENSRNOG00000008445 RatGTEx
UniProt A6HC19 ENTREZGENE, UniProtKB/TrEMBL
  D4A3W8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-22 Dact1  dishevelled-binding antagonist of beta-catenin 1  Dact1  dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-26 Dact1  dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)  Dact1  dapper homolog 1, antagonist of beta-catenin (xenopus)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Dact1  dapper homolog 1, antagonist of beta-catenin (xenopus)  RGD1564008_predicted  similar to dapper 1 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1564008_predicted  similar to dapper 1 (predicted)  LOC500666  similar to dapper 1  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC500666  similar to dapper 1      Symbol and Name status set to provisional 70820 PROVISIONAL