(+)-catechin multiple interactions ISO RGD:68623 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of DIO3 mRNA CTD PMID:24763279 (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of DIO3 mRNA] CTD PMID:31150632 17beta-estradiol affects expression ISO RGD:68623 6480464 Estradiol affects the expression of DIO3 mRNA CTD PMID:14699072 17beta-estradiol increases activity ISO RGD:68623 6480464 Estradiol results in increased activity of DIO3 protein CTD PMID:16935842 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO RGD:68623 6480464 [Environmental Pollutants results in increased abundance of 2 more ... CTD PMID:31272017 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:68624 6480464 Tetrachlorodibenzodioxin results in increased expression of DIO3 mRNA CTD PMID:32553695 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of DIO3 mRNA CTD PMID:21346803 2-Ethylhexyl acrylate decreases activity ISO RGD:68623 6480464 2-ethylhexyl acrylate results in decreased activity of DIO3 protein CTD PMID:30561685 3,3',5,5'-tetrabromobisphenol A increases expression ISO RGD:68623 6480464 tetrabromobisphenol A results in increased expression of DIO3 mRNA CTD PMID:31326446 3,3',5-triiodo-L-thyronine increases expression ISO RGD:68623 6480464 Triiodothyronine results in increased expression of DIO3 mRNA CTD PMID:23397585 3,3',5-triiodo-L-thyronine multiple interactions ISO RGD:68623 6480464 [DIO1 protein co-treated with DIO2 protein co-treated with DIO3 protein] affects the abundance of Triiodothyronine CTD PMID:23397585 4,4'-diaminodiphenylmethane decreases expression ISO RGD:68624 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of DIO3 mRNA CTD PMID:18648102 4,5-dichloro-2-n-octyl-3(2H)-isothiazolone decreases activity ISO RGD:68623 6480464 Kathon 930 results in decreased activity of DIO3 protein CTD PMID:30561685 5-aza-2'-deoxycytidine multiple interactions ISO RGD:68623 6480464 Decitabine inhibits the reaction [decabromobiphenyl ether results in decreased expression of DIO3 mRNA] CTD PMID:34166751 5-aza-2'-deoxycytidine increases expression ISO RGD:68623 6480464 Decitabine results in increased expression of DIO3 mRNA CTD PMID:34166751 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of DIO3 mRNA CTD PMID:24780913 , PMID:25825206 7,12-dimethyltetraphene increases expression ISO RGD:68624 6480464 9 more ... CTD PMID:32553695 8-Br-cAMP multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [[Hydrogen Peroxide co-treated with Sodium Selenite] promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO3 protein]] more ... CTD PMID:18420745 9-cis-retinoic acid increases activity ISO RGD:68623 6480464 Alitretinoin results in increased activity of DIO3 protein CTD PMID:16935842 acetamide increases expression EXP 6480464 acetamide results in increased expression of DIO3 mRNA CTD PMID:31881176 actinomycin D multiple interactions EXP 6480464 Dactinomycin inhibits the reaction [Hydrogen Peroxide results in increased activity of DIO3 protein] CTD PMID:18420745 all-trans-retinoic acid decreases activity ISO RGD:68623 6480464 Tretinoin results in decreased activity of DIO3 protein CTD PMID:16935842 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of DIO3 mRNA CTD PMID:20488242 all-trans-retinoic acid increases activity ISO RGD:68623 6480464 Tretinoin results in increased activity of DIO3 protein CTD PMID:16935842 alpha-hexylcinnamaldehyde decreases activity ISO RGD:68623 6480464 hexyl cinnamic aldehyde results in decreased activity of DIO3 protein CTD PMID:30561685 alpha-linolenic acid decreases activity ISO RGD:68623 6480464 alpha-Linolenic Acid results in decreased activity of DIO3 protein CTD PMID:30561685 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of DIO3 mRNA CTD PMID:16483693 benzalkonium chloride decreases activity ISO RGD:68623 6480464 Benzalkonium Compounds results in decreased activity of DIO3 protein CTD PMID:30561685 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of DIO3 mRNA CTD PMID:21839799 benzo[a]pyrene increases methylation ISO RGD:68623 6480464 Benzo(a)pyrene results in increased methylation of DIO3 promoter CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:68624 6480464 Benzo(a)pyrene metabolite results in increased expression of DIO3 mRNA CTD PMID:32553695 benzo[a]pyrene affects methylation ISO RGD:68623 6480464 Benzo(a)pyrene affects the methylation of DIO3 3' UTR CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:68624 6480464 Benzo(a)pyrene results in decreased expression of DIO3 mRNA CTD PMID:27195522 benzo[a]pyrene increases expression ISO RGD:68623 6480464 Benzo(a)pyrene results in increased expression of DIO3 mRNA CTD PMID:22316170 bicalutamide increases expression ISO RGD:68623 6480464 bicalutamide results in increased expression of DIO3 mRNA CTD PMID:15638997 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:68624 6480464 [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of DIO3 mRNA CTD PMID:33484791 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:68623 6480464 Diethylhexyl Phthalate results in decreased expression of DIO3 mRNA CTD PMID:32201330 bis(2-ethylhexyl) phthalate affects expression ISO RGD:68623 6480464 Diethylhexyl Phthalate affects the expression of DIO3 protein CTD PMID:32201330 bis(2-ethylhexyl) phthalate increases expression ISO RGD:68623 6480464 Diethylhexyl Phthalate results in increased expression of DIO3 mRNA CTD PMID:31163220 bisphenol A multiple interactions ISO RGD:68624 6480464 [potassium bromate co-treated with bisphenol A] affects the expression of DIO3 mRNA, [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of DIO3 mRNA] CTD PMID:27082013 bisphenol A increases methylation ISO RGD:68623 6480464 bisphenol A results in increased methylation of DIO3 gene CTD PMID:31601247 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of DIO3 mRNA CTD PMID:30816183 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of DIO3 gene CTD PMID:28505145 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of DIO3 mRNA CTD PMID:25181051 , PMID:30761779 Bisphenol A diglycidyl ether decreases activity ISO RGD:68623 6480464 2, 2-bis(4-glycidyloxyphenyl)propane results in decreased activity of DIO3 protein CTD PMID:30561685 C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of DIO3 mRNA CTD PMID:19167457 captafol decreases activity ISO RGD:68623 6480464 captafol results in decreased activity of DIO3 protein CTD PMID:30561685 chlordecone decreases activity ISO RGD:68623 6480464 Chlordecone results in decreased activity of DIO3 protein CTD PMID:30561685 chlorothalonil decreases activity ISO RGD:68623 6480464 tetrachloroisophthalonitrile results in decreased activity of DIO3 protein CTD PMID:30561685 choline multiple interactions ISO RGD:68624 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DIO3 gene CTD PMID:20938992 cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of DIO3 mRNA CTD PMID:22023808 clothianidin increases expression ISO RGD:68623 6480464 clothianidin results in increased expression of DIO3 mRNA CTD PMID:31626844 colforsin daropate hydrochloride multiple interactions EXP 6480464 Colforsin promotes the reaction [Hydrogen Peroxide results in increased expression of DIO3 mRNA] CTD PMID:18420745 copper atom decreases expression EXP 6480464 Copper results in decreased expression of DIO3 mRNA CTD PMID:30556269 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of DIO3 mRNA CTD PMID:30556269 Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of DIO3 mRNA CTD PMID:27523638 cycloheximide multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [Hydrogen Peroxide results in increased activity of DIO3 protein] CTD PMID:18420745 Cyclopamine decreases expression ISO RGD:68623 6480464 cyclopamine results in decreased expression of DIO3 mRNA CTD PMID:26825960 DDE multiple interactions ISO RGD:68623 6480464 [Environmental Pollutants results in increased abundance of Dichlorodiphenyl Dichloroethylene] which results in increased methylation of DIO3 promoter CTD PMID:31272017 decabromodiphenyl ether decreases expression ISO RGD:68623 6480464 decabromobiphenyl ether results in decreased expression of DIO3 mRNA, decabromobiphenyl ether results in decreased expression of DIO3 protein CTD PMID:34166751 decabromodiphenyl ether multiple interactions ISO RGD:68623 6480464 Decitabine inhibits the reaction [decabromobiphenyl ether results in decreased expression of DIO3 mRNA] CTD PMID:34166751 dexamethasone decreases activity ISO RGD:68623 6480464 Dexamethasone results in decreased activity of DIO3 protein CTD PMID:16935842 Didecyldimethylammonium decreases activity ISO RGD:68623 6480464 didecyldimethylammonium results in decreased activity of DIO3 protein CTD PMID:30561685 diethyl hydrogen phosphate increases expression EXP 6480464 diethyl phosphate results in increased expression of DIO3 mRNA CTD PMID:31835022 dinocap decreases activity ISO RGD:68623 6480464 dinocap results in decreased activity of DIO3 protein CTD PMID:30561685 disodium selenite multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [[Hydrogen Peroxide co-treated with Sodium Selenite] promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO3 protein]], Sodium Selenite inhibits the reaction [Hydrogen Peroxide results in increased activity of DIO3 protein] CTD PMID:18420745 dorsomorphin multiple interactions ISO RGD:68623 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DIO3 mRNA CTD PMID:27188386 entinostat multiple interactions ISO RGD:68623 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DIO3 mRNA CTD PMID:27188386 entinostat decreases expression ISO RGD:68623 6480464 entinostat results in decreased expression of DIO3 mRNA CTD PMID:26272509 fenvalerate increases expression EXP 6480464 fenvalerate results in increased expression of DIO3 mRNA CTD PMID:30307764 fipronil increases expression EXP 6480464 fipronil results in increased expression of DIO3 mRNA CTD PMID:23962444 fipronil decreases activity ISO RGD:68623 6480464 fipronil results in decreased activity of DIO3 protein CTD PMID:30561685 flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of DIO3 mRNA CTD PMID:18035473 fluazinam decreases activity ISO RGD:68623 6480464 fluazinam results in decreased activity of DIO3 protein CTD PMID:30561685 fluoxetine multiple interactions EXP 6480464 SB 203580 inhibits the reaction [Fluoxetine results in increased expression of DIO3 mRNA] more ... CTD PMID:15456934 fluoxetine increases activity EXP 6480464 Fluoxetine results in increased activity of DIO3 protein CTD PMID:15456934 fluoxetine increases expression EXP 6480464 Fluoxetine results in increased expression of DIO3 mRNA CTD PMID:15456934 folic acid multiple interactions ISO RGD:68624 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DIO3 gene CTD PMID:20938992 folic acid increases expression ISO RGD:68624 6480464 Folic Acid results in increased expression of DIO3 mRNA CTD PMID:26547318 furan increases expression EXP 6480464 furan results in increased expression of DIO3 mRNA CTD PMID:26194646 glyphosate decreases expression EXP 6480464 glyphosate results in decreased expression of DIO3 mRNA CTD PMID:27916585 , PMID:33512083 hydrogen peroxide multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [[Hydrogen Peroxide co-treated with Sodium Selenite] promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO3 protein]] more ... CTD PMID:18420745 hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of DIO3 mRNA CTD PMID:18420745 hydrogen peroxide increases activity EXP 6480464 Hydrogen Peroxide results in increased activity of DIO3 protein CTD PMID:18420745 L-methionine multiple interactions ISO RGD:68624 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DIO3 gene CTD PMID:20938992 Licochalcone B increases expression ISO RGD:68623 6480464 licochalcone B results in increased expression of DIO3 mRNA CTD PMID:33647349 lidocaine decreases expression EXP 6480464 Lidocaine results in decreased expression of DIO3 mRNA CTD PMID:35283115 linoleic acid decreases activity ISO RGD:68623 6480464 Linoleic Acid results in decreased activity of DIO3 protein CTD PMID:30561685 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of DIO3 mRNA CTD PMID:16415329 lipopolysaccharide multiple interactions EXP 6480464 Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of DIO3 mRNA] CTD PMID:16415329 lithocholic acid increases activity ISO RGD:68624 6480464 Lithocholic Acid results in increased activity of DIO3 protein CTD PMID:19036883 masoprocol decreases activity ISO RGD:68623 6480464 Masoprocol results in decreased activity of DIO3 protein CTD PMID:30561685 methoxychlor increases methylation EXP 6480464 Methoxychlor results in increased methylation of DIO3 gene CTD PMID:23303685 methylmercury chloride increases expression ISO RGD:68623 6480464 methylmercuric chloride results in increased expression of DIO3 mRNA CTD PMID:28001369 methyltrioctylammonium chloride decreases activity ISO RGD:68623 6480464 trioctylmethylammonium results in decreased activity of DIO3 protein CTD PMID:30561685 morin decreases activity ISO RGD:68623 6480464 morin results in decreased activity of DIO3 protein CTD PMID:30561685 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [[Hydrogen Peroxide co-treated with Sodium Selenite] promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO3 protein]], Acetylcysteine inhibits the reaction [Hydrogen Peroxide promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO3 protein]] CTD PMID:18420745 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine multiple interactions EXP 6480464 Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of DIO3 mRNA] CTD PMID:16415329 naphthalene increases expression ISO RGD:68624 6480464 naphthalene results in increased expression of DIO3 mRNA CTD PMID:18978301 octhilinone decreases activity ISO RGD:68623 6480464 2-n-octyl-4-isothiazolin-3-one results in decreased activity of DIO3 protein CTD PMID:30561685 ozone increases expression ISO RGD:68624 6480464 Ozone results in increased expression of DIO3 mRNA CTD PMID:31626304 pentachlorophenol decreases expression EXP 6480464 Pentachlorophenol results in decreased expression of DIO3 mRNA CTD PMID:20654147 pentachlorophenol increases expression EXP 6480464 Pentachlorophenol results in increased expression of DIO3 mRNA CTD PMID:20654147 perfluorooctane-1-sulfonic acid affects expression EXP 6480464 perfluorooctane sulfonic acid affects the expression of DIO3 mRNA CTD PMID:17383973 perfluorooctanoic acid affects expression EXP 6480464 perfluorooctanoic acid affects the expression of DIO3 mRNA CTD PMID:17383973 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of DIO3 mRNA CTD PMID:19631232 phorbol 13-acetate 12-myristate increases activity ISO RGD:68623 6480464 Tetradecanoylphorbol Acetate results in increased activity of DIO3 protein CTD PMID:16935842 phorbol 13-acetate 12-myristate increases activity EXP 6480464 Tetradecanoylphorbol Acetate results in increased activity of DIO3 protein CTD PMID:18420745 phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 Hydrogen Peroxide promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of DIO3 protein] CTD PMID:18420745 phthalaldehyde decreases activity ISO RGD:68623 6480464 o-Phthalaldehyde results in decreased activity of DIO3 protein CTD PMID:30561685 pioglitazone decreases activity ISO RGD:68624 6480464 pioglitazone results in decreased activity of DIO3 protein CTD PMID:19036883 potassium bromate multiple interactions ISO RGD:68624 6480464 [potassium bromate co-treated with bisphenol A] affects the expression of DIO3 mRNA, [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of DIO3 mRNA] CTD PMID:27082013 pravastatin decreases expression ISO RGD:68624 6480464 Pravastatin results in decreased expression of DIO3 mRNA CTD PMID:27225895 pravastatin decreases expression EXP 6480464 Pravastatin results in decreased expression of DIO3 mRNA CTD PMID:27225895 propiconazole affects expression EXP 6480464 propiconazole affects the expression of DIO3 mRNA CTD PMID:17383973 quinoxyfen decreases activity ISO RGD:68623 6480464 quinoxyfen results in decreased activity of DIO3 protein CTD PMID:30561685 ranitidine multiple interactions EXP 6480464 Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of DIO3 mRNA] CTD PMID:16415329 resveratrol multiple interactions ISO RGD:68623 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of DIO3 mRNA CTD PMID:23557933 S-butyl-DL-homocysteine (S,R)-sulfoximine increases activity EXP 6480464 Buthionine Sulfoximine results in increased activity of DIO3 protein CTD PMID:18420745 SB 203580 decreases expression ISO RGD:68623 6480464 SB 203580 results in decreased expression of DIO3 CTD PMID:26825960 SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [Fluoxetine results in increased expression of DIO3 mRNA] more ... CTD PMID:15456934 , PMID:18420745 SB 431542 multiple interactions ISO RGD:68623 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DIO3 mRNA CTD PMID:27188386 streptozocin multiple interactions ISO RGD:68624 6480464 [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of DIO3 mRNA CTD PMID:33484791 Tetrachlorobisphenol A increases expression ISO RGD:68623 6480464 tetrachlorodian results in increased expression of DIO3 mRNA CTD PMID:31326446 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of DIO3 mRNA CTD PMID:31150632 tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of DIO3 mRNA] CTD PMID:31150632 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of DIO3 protein CTD PMID:23586759 thyroxine increases activity EXP 6480464 Thyroxine results in increased activity of DIO3 protein CTD PMID:18420745 thyroxine multiple interactions EXP 6480464 Hydrogen Peroxide promotes the reaction [Thyroxine results in increased activity of DIO3 protein] CTD PMID:18420745 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of DIO3 mRNA CTD PMID:30012374 triadimefon affects expression EXP 6480464 triadimefon affects the expression of DIO3 mRNA CTD PMID:17383973 triflumizole decreases activity ISO RGD:68623 6480464 triflumizol results in decreased activity of DIO3 protein CTD PMID:30561685 triptonide increases expression ISO RGD:68624 6480464 triptonide results in increased expression of DIO3 mRNA CTD PMID:33045310 valproic acid increases methylation ISO RGD:68623 6480464 Valproic Acid results in increased methylation of DIO3 gene CTD PMID:29154799 valproic acid decreases expression ISO RGD:68623 6480464 Valproic Acid results in decreased expression of DIO3 mRNA CTD PMID:28001369 vemurafenib decreases expression ISO RGD:68623 6480464 vemurafenib results in decreased expression of DIO3 CTD PMID:26825960 xanthohumol decreases activity ISO RGD:68623 6480464 xanthohumol results in decreased activity of DIO3 protein CTD PMID:30561685 zoxamide decreases activity ISO RGD:68623 6480464 zoxamide results in decreased activity of DIO3 protein CTD PMID:30561685
