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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68420
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dio3
Name: iodothyronine deiodinase 3
Acc ID: CHEBI:81936
Term: octhilinone
Definition: A member of the class of 1,2-thiazole that is 1,2-thiazol-3-one substituted on the nitrogen (position 2) by an octyl group. A fungicide and antibacterial agent, it is used for treatment of canker and other fungal and bacterial diseases in fruit trees. It is no longer approved for use within the European Union.
Chemical ID: MESH:C035331
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dio3decreases activityISODIO3 (Homo sapiens)6480464CTD2-n-octyl-4-isothiazolin-3-one results in decreased activity of DIO3 proteinPMID:30561685
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