 Gene-Chemical Interaction Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsMolecular Pathway Annotations |
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Analyze GeneStrainQTL List |
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Gene Annotator (Annotation Comparison) |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Gene Ontology AnnotationsMolecular Pathway AnnotationsDisease AnnotationsGene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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Molecular Pathway Annotations
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References - curated| 1. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | GOA data from the GO Consortium |
| 3. | MGD data from the GO Consortium |
| 4. | Pipeline to import KEGG annotations from KEGG into RGD |
| 5. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 6. | RGD automated import pipeline for gene-chemical interactions |
Genomics
Comparative Map Data| Ppp2r5e (Rattus norvegicus - Norway rat) |
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| PPP2R5E (Homo sapiens - human) |
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| Ppp2r5e (Mus musculus - house mouse) |
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| Ppp2r5e (Chinchilla lanigera - long-tailed chinchilla) |
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| PPP2R5E (Pan paniscus - bonobo/pygmy chimpanzee) |
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| PPP2R5E (Canis lupus familiaris - dog) |
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| Ppp2r5e (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| PPP2R5E (Sus scrofa - pig) |
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| PPP2R5E (Chlorocebus sabaeus - African green monkey) |
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| Ppp2r5e (Heterocephalus glaber - naked mole-rat) |
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Position Markers| RH132173 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | 3 | 26 | 32 | 18 | 18 | 18 | 1 | 2 | 74 | 33 | 41 | 11 | 1 |
| Low | 17 | 25 | 23 | 1 | 23 | 7 | 9 | 2 | 7 | ||||
| Below cutoff |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_001106740 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_006240222 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006240223 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006240224 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017594093 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07064866 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AAHX01045166 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01045167 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01045168 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01045169 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01045170 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01045171 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01045172 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473947 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | ENSRNOT00000006755 ⟹ ENSRNOP00000006755 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | ENSRNOT00000077715 ⟹ ENSRNOP00000068628 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_001106740 ⟹ NP_001100210 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
GCATTGACGGGGACCCTGCGCGGGTAGCGAACGGCGGCTCTGGCAGCGGCGGCTCAGGCGGCTChide sequence |
| RefSeq Acc Id: | XM_006240222 ⟹ XP_006240284 | ||||||||||||
| RefSeq Status: | |||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Sequence: |
TGCCATGGACTCAGCCGCCCGGTGATATTGACAATAGGAGAGAGAAAGGGGCATTGACGGGGAChide sequence |
| RefSeq Acc Id: | XM_006240223 ⟹ XP_006240285 | ||||||||||||
| RefSeq Status: | |||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Sequence: |
TGCCATGGACTCAGCCGCCCGGTGATATTGACAATAGGAGAGAGAAAGGGGCATTGACGGGGAChide sequence |
| RefSeq Acc Id: | XM_006240224 ⟹ XP_006240286 | ||||||||||||
| RefSeq Status: | |||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Sequence: |
CTCTTGCCTCTGCCTTCCAAGTGCTGGGGTTCCTAGTGTATGCCACTGTGATTGTTTGCTCCTThide sequence |
| RefSeq Acc Id: | XM_017594093 ⟹ XP_017449582 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
TGTCCCTTATGCAGGTCTTGTGCAGTCAGGCCTAGCCTGTTCCATGGTCACCTCGCTGAGATGGhide sequence |
Protein Sequences| Protein RefSeqs | NP_001100210 | (Get FASTA) | NCBI Sequence Viewer |
| XP_006240284 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006240285 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006240286 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017449582 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | EDM03634 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_001100210 ⟸ NM_001106740 |
| - UniProtKB: | D3ZHI9 (UniProtKB/TrEMBL) |
| - Sequence: |
MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPTSEQPELFLhide sequence |
| RefSeq Acc Id: | XP_006240285 ⟸ XM_006240223 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A0G2JTA1 (UniProtKB/TrEMBL) |
| - Sequence: |
MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPTSEQPELFLhide sequence |
| RefSeq Acc Id: | XP_006240284 ⟸ XM_006240222 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A0G2JTA1 (UniProtKB/TrEMBL) |
| - Sequence: |
MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPTSEQPELFLhide sequence |
| RefSeq Acc Id: | XP_006240286 ⟸ XM_006240224 |
| - Peptide Label: | isoform X2 |
| - Sequence: |
MFHLEAVKLARVGAREGVLGSLKGRSYYDVPTSEQPELFLKKLQQCCVIFDFMDTLSDLKMKEYhide sequence |
| RefSeq Acc Id: | XP_017449582 ⟸ XM_017594093 |
| - Peptide Label: | isoform X3 |
| - Sequence: |
MLEDVPTSEQPELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPhide sequence |
| RefSeq Acc Id: | ENSRNOP00000006755 ⟸ ENSRNOT00000006755 |
| RefSeq Acc Id: | ENSRNOP00000068628 ⟸ ENSRNOT00000077715 |
TranscriptomePromoters| RGD ID: | 13694672 | ||||||||
| Promoter ID: | EPDNEW_R5195 | ||||||||
| Type: | initiation region | ||||||||
| Name: | Ppp2r5e_1 | ||||||||
| Description: | protein phosphatase 2 regulatory subunit B', epsilon | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1305657 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000005045 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000006755 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOP00000068628 | ENTREZGENE, UniProtKB/TrEMBL | |
| Ensembl Transcript | ENSRNOT00000006755 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOT00000077715 | ENTREZGENE, UniProtKB/TrEMBL | |
| Gene3D-CATH | 1.25.10.10 | UniProtKB/TrEMBL |
| InterPro | ARM-like | UniProtKB/TrEMBL |
| ARM-type_fold | UniProtKB/TrEMBL | |
| PP2A_B56 | UniProtKB/TrEMBL | |
| KEGG Report | rno:299147 | UniProtKB/TrEMBL |
| NCBI Gene | 299147 | ENTREZGENE |
| PANTHER | B56 | UniProtKB/TrEMBL |
| Pfam | B56 | UniProtKB/TrEMBL |
| PhenoGen | Ppp2r5e | PhenoGen |
| PIRSF | PP2A_B56 | UniProtKB/TrEMBL |
| Superfamily-SCOP | ARM-type_fold | UniProtKB/TrEMBL |
| UniGene | Rn.24394 | ENTREZGENE |
| UniProt | A0A0G2JTA1 | ENTREZGENE, UniProtKB/TrEMBL |
| D3ZHI9 | ENTREZGENE, UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2015-11-30 | Ppp2r5e | protein phosphatase 2 regulatory subunit B', epsilon | Ppp2r5e | protein phosphatase 2, regulatory subunit B', epsilon isoform | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2008-12-15 | Ppp2r5e | protein phosphatase 2, regulatory subunit B', epsilon isoform | Ppp2r5e | protein phosphatase 2, regulatory subunit B (B56), epsilon isoform | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2008-04-30 | Ppp2r5e | protein phosphatase 2, regulatory subunit B (B56), epsilon isoform | Ppp2r5e_predicted | protein phosphatase 2, regulatory subunit B (B56), epsilon isoform (predicted) | 'predicted' is removed | 2292626 | APPROVED |
| 2005-01-12 | Ppp2r5e_predicted | protein phosphatase 2, regulatory subunit B (B56), epsilon isoform (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |
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| More on Ppp2r5e | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 1305657 |
| Created: | 2005-01-12 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-09-09 |
| Status: | ACTIVE |
