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Gene: Wars1 (tryptophanyl-tRNA synthetase 1) Rattus norvegicus
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Symbol: Wars1
Name: tryptophanyl-tRNA synthetase 1
Description: Predicted to have several functions, including kinase inhibitor activity; protein homodimerization activity; and tryptophan-tRNA ligase activity. Predicted to be involved in several processes, including regulation of angiogenesis; regulation of protein modification process; and tryptophanyl-tRNA aminoacylation. Predicted to localize to cytosol; nucleus; and protein-containing complex. Human ortholog(s) of this gene implicated in distal hereditary motor neuronopathy type 9. Orthologous to human WARS1 (tryptophanyl-tRNA synthetase 1); PARTICIPATES IN tryptophan metabolic pathway; aminoacyl-tRNA biosynthetic pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC314442; trpRS; tryptophan--tRNA ligase; tryptophan--tRNA ligase, cytoplasmic; tryptophanyl-tRNA synthetase; tryptophanyl-tRNA synthetase, cytoplasmic; Wars
Orthologs:
Homo sapiens (human) : WARS1 (tryptophanyl-tRNA synthetase 1)  HGNC  Alliance
Mus musculus (house mouse) : Wars (tryptophanyl-tRNA synthetase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wars1 (tryptophanyl-tRNA synthetase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : WARS1 (tryptophanyl-tRNA synthetase 1)
Canis lupus familiaris (dog) : WARS1 (tryptophanyl-tRNA synthetase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wars1 (tryptophanyl-tRNA synthetase 1)
Sus scrofa (pig) : WARS1 (tryptophanyl-tRNA synthetase 1)
Chlorocebus sabaeus (African green monkey) : WARS1 (tryptophanyl-tRNA synthetase 1)
Heterocephalus glaber (naked mole-rat) : Wars1 (tryptophanyl-tRNA synthetase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.06132,771,026 - 132,802,262 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6132,771,021 - 132,802,210 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06141,941,102 - 141,972,312 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46133,200,866 - 133,232,048 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16133,207,052 - 133,238,235 (-)NCBI
Celera6125,326,985 - 125,358,157 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Wars1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308278
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.