Vti1b (vesicle transport through interaction with t-SNAREs 1B) - Rat Genome Database

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Gene: Vti1b (vesicle transport through interaction with t-SNAREs 1B) Rattus norvegicus
Analyze
Symbol: Vti1b
Name: vesicle transport through interaction with t-SNAREs 1B
RGD ID: 2323682
Description: Predicted to enable SNAP receptor activity; SNARE binding activity; and chloride channel inhibitor activity. Predicted to be involved in several processes, including Golgi vesicle transport; regulation of protein localization to plasma membrane; and retrograde transport, endosome to Golgi. Located in neuronal cell body and synaptic vesicle. Part of SNARE complex. Is active in presynaptic endosome membrane. Orthologous to human VTI1B (vesicle transport through interaction with t-SNAREs 1B); INTERACTS WITH 4,4'-sulfonyldiphenol; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100359512; LOC366673; RGD1560475; similar to vesicle transport through interaction with t-SNAREs 1B homolog; vesicle transport through interaction with t-SNAREs 1B-like; Vesicle transport through interaction with t-SNAREs homolog 1B; Vesicle transport v-SNARE protein Vti1-like 1; Vti1-rp1; Vti1l1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86103,694,342 - 103,709,544 (-)NCBIGRCr8
mRatBN7.2697,957,700 - 97,976,491 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl697,961,346 - 97,976,465 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx698,392,592 - 98,405,961 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0698,691,744 - 98,705,104 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0698,077,883 - 98,091,234 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06102,340,261 - 102,353,612 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6102,339,857 - 102,353,403 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06115,026,935 - 115,040,283 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46101,928,449 - 101,943,347 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera696,346,498 - 96,361,515 (-)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
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Original Reference(s)
Vti1bRatLeber congenital amaurosis 13  ISORGD:13529018554872ClinVar Annotator: match by term: Leber congenital amaurosis 13ClinVarPMID:28492532

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Original Reference(s)
Vti1bRat1,2-dimethylhydrazine multiple interactionsISORGD:16215596480464[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of VTI1B mRNACTDPMID:22206623
Vti1bRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:16215596480464Tetrachlorodibenzodioxin affects the expression of VTI1B mRNACTDPMID:21570461
Vti1bRat2-hydroxypropanoic acid decreases expressionISORGD:13529016480464Lactic Acid results in decreased expression of VTI1B mRNACTDPMID:30851411
Vti1bRat4,4'-sulfonyldiphenol increases expressionISORGD:16215596480464bisphenol S results in increased expression of VTI1B mRNACTDPMID:39298647
Vti1bRat4,4'-sulfonyldiphenol increases expressionISORGD:13529016480464bisphenol S results in increased expression of VTI1B proteinCTDPMID:34186270
Vti1bRat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ...CTDPMID:36041667
Vti1bRatammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of VTI1B mRNACTDPMID:16483693
Vti1bRataristolochic acid A decreases expressionISORGD:13529016480464aristolochic acid I results in decreased expression of VTI1B mRNACTDPMID:33212167
Vti1bRatbenzo[a]pyrene increases expressionISORGD:16215596480464Benzo(a)pyrene results in increased expression of VTI1B mRNACTDPMID:22228805
Vti1bRatbisphenol A multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ...CTDPMID:36041667
Vti1bRatbisphenol AF increases expressionISORGD:13529016480464bisphenol AF results in increased expression of VTI1B proteinCTDPMID:34186270
Vti1bRatBisphenol B increases expressionISORGD:13529016480464bisphenol B results in increased expression of VTI1B proteinCTDPMID:34186270
Vti1bRatbisphenol F increases expressionISORGD:16215596480464bisphenol F results in increased expression of VTI1B mRNACTDPMID:38685157
Vti1bRatbisphenol F increases expressionISORGD:13529016480464bisphenol F results in increased expression of VTI1B proteinCTDPMID:34186270
Vti1bRatbisphenol F multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ...CTDPMID:36041667
Vti1bRatBrodifacoum decreases expressionEXP 6480464bromfenacoum results in decreased expression of VTI1B proteinCTDPMID:28903499
Vti1bRatcadmium dichloride decreases expressionISORGD:13529016480464Cadmium Chloride results in decreased expression of VTI1B mRNACTDPMID:38568856
Vti1bRatchlorpyrifos increases expressionISORGD:16215596480464Chlorpyrifos results in increased expression of VTI1B mRNACTDPMID:37019170
Vti1bRatcholine multiple interactionsISORGD:16215596480464[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ...CTDPMID:20938992
Vti1bRatcopper(II) sulfate decreases expressionISORGD:13529016480464Copper Sulfate results in decreased expression of VTI1B mRNACTDPMID:19549813

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Biological Process
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Original Reference(s)
Vti1bRatautophagosome maturation NOT|involved_inISORGD:13529011624291 PMID:23217709RGDPMID:23217709
Vti1bRatGolgi to vacuole transport involved_inIBAPANTHER:PTN000477548|SGD:S0000048101600115GO_REF:0000033GO_CentralGO_REF:0000033
Vti1bRatintra-Golgi vesicle-mediated transport involved_inIBAPANTHER:PTN000477548|SGD:S0000048101600115GO_REF:0000033GO_CentralGO_REF:0000033
Vti1bRatintracellular protein transport involved_inIEAInterPro:IPR0077051600115GO_REF:0000002InterProGO_REF:0000002
Vti1bRatmacroautophagy involved_inIBAPANTHER:PTN000477548|SGD:S0000048101600115GO_REF:0000033GO_CentralGO_REF:0000033
Vti1bRatprotein transport involved_inIEAUniProtKB-KW:KW-06531600115GO_REF:0000043UniProtGO_REF:0000043
Vti1bRatregulation of protein localization to plasma membrane involved_inISORGD:13529011624291 PMID:18570918RGDPMID:18570918
Vti1bRatregulation of protein localization to plasma membrane involved_inIBAPANTHER:PTN001081713|UniProtKB:Q9UEU01600115GO_REF:0000033GO_CentralGO_REF:0000033
Vti1bRatregulation of protein localization to plasma membrane involved_inIEAUniProtKB:Q9UEU0|ensembl:ENSP000004507311600115GO_REF:0000107EnsemblGO_REF:0000107
Vti1bRatretrograde transport, endosome to Golgi involved_inIBAPANTHER:PTN000477548|UniProtKB:Q96AJ91600115GO_REF:0000033GO_CentralGO_REF:0000033
Vti1bRatvesicle fusion with Golgi apparatus involved_inIBAPANTHER:PTN000477548|RGD:6214901600115GO_REF:0000033GO_CentralGO_REF:0000033
Vti1bRatvesicle-mediated transport involved_inIEAInterPro:IPR0109891600115GO_REF:0000002InterProGO_REF:0000002
Vti1bRatvesicle-mediated transport involved_inIEAInterPro:IPR010989|InterPro:IPR0270271600115GO_REF:0000002InterProGO_REF:0000002
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Cellular Component
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Original Reference(s)
Vti1bRatcytoplasm located_inIEAARBA:ARBA000269711600115GO_REF:0000117UniProtGO_REF:0000117
Vti1bRatcytosol located_inIEAGO:00421471600115GO_REF:0000108GOCGO_REF:0000108
Vti1bRatearly endosome membrane located_inIEAUniProtKB:Q9UEU0|ensembl:ENSP000004507311600115GO_REF:0000107EnsemblGO_REF:0000107
Vti1bRatearly endosome membrane located_inIEAUniProtKB-SubCell:SL-00931600115GO_REF:0000044UniProtGO_REF:0000044
Vti1bRatearly endosome membrane located_inISORGD:13529011624291 PMID:18033301RGDPMID:18033301
Vti1bRatendomembrane system located_inIEAUniProtKB-SubCell:SL-01471600115GO_REF:0000044UniProtGO_REF:0000044
Vti1bRatendomembrane system located_inIEAARBA:ARBA000289531600115GO_REF:0000117UniProtGO_REF:0000117
Vti1bRatendoplasmic reticulum membrane is_active_inIBAMGI:1927204|PANTHER:PTN000477446|SGD:S0000040681600115GO_REF:0000033GO_CentralGO_REF:0000033
Vti1bRatendosome located_inIEAUniProtKB-KW:KW-09671600115GO_REF:0000043UniProtGO_REF:0000043
Vti1bRatER to Golgi transport vesicle membrane is_active_inIBAPANTHER:PTN000477446|SGD:S0000040681600115GO_REF:0000033GO_CentralGO_REF:0000033
Vti1bRatGolgi apparatus located_inISORGD:13529011624291 PMID:19224922RGDPMID:19224922
Vti1bRatGolgi apparatus located_inIEAInterPro:IPR0270271600115GO_REF:0000002InterProGO_REF:0000002
Vti1bRatGolgi apparatus located_inISORGD:16215591624291 PMID:11784862RGDPMID:11784862
Vti1bRatGolgi apparatus is_active_inIBAMGI:1855688|MGI:1927204|PANTHER:PTN000477446|SGD:S000004810|TAIR:locus:2057946|TAIR:locus:2175733|TAIR:locus:2177512|UniProtKB:O14653|UniProtKB:Q96AJ9|UniProtKB:Q9UEU01600115GO_REF:0000033GO_CentralGO_REF:0000033
Vti1bRatGolgi apparatus located_inIEAUniProtKB:Q9UEU0|ensembl:ENSP000004507311600115GO_REF:0000107EnsemblGO_REF:0000107
Vti1bRatGolgi apparatus located_inISORGD:1352901|UniProtKB:Q9UEU0-11624291 RGDGO_REF:0000052
Vti1bRatlate endosome membrane located_inIEAUniProtKB:Q9UEU0|ensembl:ENSP000004507311600115GO_REF:0000107EnsemblGO_REF:0000107
Vti1bRatlate endosome membrane located_inIEAUniProtKB-SubCell:SL-01511600115GO_REF:0000044UniProtGO_REF:0000044
Vti1bRatlate endosome membrane is_active_inIBAPANTHER:PTN000477446|UniProtKB:Q9UEU01600115GO_REF:0000033GO_CentralGO_REF:0000033
Vti1bRatlate endosome membrane located_inISORGD:13529011624291 PMID:18033301, PMID:23217709RGDPMID:18033301|PMID:23217709
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Molecular Function
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Original Reference(s)
Vti1bRatchloride channel inhibitor activity enablesIEAUniProtKB:Q9UEU0|ensembl:ENSP000004507311600115GO_REF:0000107EnsemblGO_REF:0000107
Vti1bRatchloride channel inhibitor activity enablesISORGD:13529011624291 PMID:18570918RGDPMID:18570918
Vti1bRatprotein binding enablesISORGD:16215591624291PR:Q8R307|UniProtKB:P70280|UniProtKB:Q14677 PMID:14668490, PMID:18033301, PMID:20871593, PMID:23104059RGDPMID:14668490|PMID:18033301|PMID:20871593|PMID:23104059
Vti1bRatprotein binding enablesIPIUniProtKB:Q9R0N38693368PMID:24882364ParkinsonsUK-UCL 
Vti1bRatprotein binding enablesISORGD:13529011624291UniProtKB:O60669|UniProtKB:P07307-3|UniProtKB:P11912|UniProtKB:P12314|UniProtKB:P13569|UniProtKB:P15529-3|UniProtKB:P26715|UniProtKB:P32856-2|UniProtKB:P54829|UniProtKB:P60409|UniProtKB:Q12846|UniProtKB:Q13520|UniProtKB:Q14677|UniProtKB:Q16623|UniProtKB:Q5T700|UniProtKB:Q6P5S7|UniProtKB:Q8IWR1|UniProtKB:Q8N205|UniProtKB:Q8N5M9|UniProtKB:Q8N6L0|UniProtKB:Q8TED1|UniProtKB:Q8WY98|UniProtKB:Q9BUF7-2|UniProtKB:Q9H6H4|UniProtKB:Q9NQG1|UniProtKB:Q9NQQ7-3|UniProtKB:Q9NUH8|UniProtKB:Q9NW97|UniProtKB:Q9UNK0|UniProtKB:Q9Y282 PMID:16189514, PMID:18033301, PMID:21516116, PMID:25416956, PMID:28514442, PMID:31515488, PMID:32296183, PMID:33961781, PMID:35156780, PMID:35271311, PMID:36012204RGDPMID:16189514|PMID:18033301|PMID:21516116|PMID:25416956|PMID:28514442|PMID:31515488|PMID:32296183|PMID:33961781|PMID:35156780|PMID:35271311|PMID:36012204
Vti1bRatSNAP receptor activity enablesIBAPANTHER:PTN000477446|SGD:S000004068|SGD:S000004810|UniProtKB:Q96AJ91600115GO_REF:0000033GO_CentralGO_REF:0000033
Vti1bRatSNAP receptor activity enablesIEAInterPro:IPR0270271600115GO_REF:0000002InterProGO_REF:0000002
Vti1bRatSNARE binding enablesISORGD:13529011624291 PMID:24550300RGDPMID:24550300
Vti1bRatSNARE binding enablesIBAPANTHER:PTN000477446|UniProtKB:Q9UEU01600115GO_REF:0000033GO_CentralGO_REF:0000033
Vti1bRatSNARE binding enablesIEAUniProtKB:Q9UEU0|ensembl:ENSP000004507311600115GO_REF:0000107EnsemblGO_REF:0000107
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#
Reference Title
Reference Citation
1. The SNARE Vti1a-beta is localized to small synaptic vesicles and participates in a novel SNARE complex. Antonin W, etal., J Neurosci 2000 Aug 1;20(15):5724-32.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Synaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic beta-cells. Milochau A, etal., FEBS Lett. 2014 Jun 27;588(14):2217-22. doi: 10.1016/j.febslet.2014.05.031. Epub 2014 May 29.
4. Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events. Pryor PR, etal., EMBO Rep. 2004 Jun;5(6):590-5. Epub 2004 May 7.
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:11101518   PMID:11784862   PMID:18033301   PMID:18321981   PMID:18570918   PMID:19224922   PMID:23217709   PMID:24550300   PMID:29437892  



Vti1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86103,694,342 - 103,709,544 (-)NCBIGRCr8
mRatBN7.2697,957,700 - 97,976,491 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl697,961,346 - 97,976,465 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx698,392,592 - 98,405,961 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0698,691,744 - 98,705,104 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0698,077,883 - 98,091,234 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06102,340,261 - 102,353,612 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6102,339,857 - 102,353,403 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06115,026,935 - 115,040,283 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46101,928,449 - 101,943,347 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera696,346,498 - 96,361,515 (-)NCBICelera
Cytogenetic Map6q24NCBI
VTI1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381467,647,085 - 67,674,632 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1467,647,085 - 67,674,820 (-)EnsemblGRCh38hg38GRCh38
GRCh371468,113,802 - 68,141,349 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361467,187,619 - 67,211,301 (-)NCBINCBI36Build 36hg18NCBI36
Build 341467,187,618 - 67,211,301NCBI
Celera1448,176,927 - 48,200,645 (-)NCBICelera
Cytogenetic Map14q24.1NCBI
HuRef1448,287,563 - 48,311,281 (-)NCBIHuRef
CHM1_11468,056,646 - 68,080,381 (-)NCBICHM1_1
T2T-CHM13v2.01461,854,218 - 61,881,753 (-)NCBIT2T-CHM13v2.0
Vti1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391279,202,791 - 79,219,428 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1279,202,791 - 79,219,441 (-)EnsemblGRCm39 Ensembl
GRCm381279,156,017 - 79,172,685 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1279,156,017 - 79,172,667 (-)EnsemblGRCm38mm10GRCm38
MGSCv371280,257,004 - 80,273,445 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361280,075,098 - 80,091,217 (-)NCBIMGSCv36mm8
Celera1280,620,461 - 80,636,902 (-)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1235.51NCBI
Vti1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554662,527,753 - 2,549,568 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554662,527,750 - 2,549,599 (+)NCBIChiLan1.0ChiLan1.0
VTI1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21568,761,673 - 68,786,707 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11467,978,185 - 68,001,944 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01448,227,203 - 48,254,990 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11467,105,160 - 67,134,351 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1467,105,160 - 67,134,351 (-)Ensemblpanpan1.1panPan2
VTI1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1841,619,365 - 41,650,389 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2919,153,616 - 19,154,245 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl841,614,921 - 41,669,576 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha841,312,675 - 41,341,742 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0841,848,085 - 41,879,357 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl841,829,333 - 41,879,799 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1841,467,045 - 41,496,369 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0841,540,458 - 41,569,783 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0841,900,036 - 41,929,107 (-)NCBIUU_Cfam_GSD_1.0
Vti1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864063,127,656 - 63,147,822 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649511,045,429 - 11,064,206 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649511,043,813 - 11,064,113 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VTI1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl791,374,640 - 91,413,607 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1791,386,020 - 91,413,480 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2797,693,164 - 97,720,791 (-)NCBISscrofa10.2Sscrofa10.2susScr3
VTI1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12444,884,082 - 44,907,819 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2444,884,315 - 44,907,771 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605333,110,909 - 33,137,704 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vti1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473433,299,373 - 33,321,199 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473433,299,732 - 33,341,672 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Vti1b
58 total Variants

1 to 10 of 33 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat

1 to 10 of 33 rows
BF386764  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.46101,928,292 - 101,928,470UniSTSRGSC3.4
Celera696,346,541 - 96,346,719UniSTS
RH 3.4 Map6691.09UniSTS
Cytogenetic Map6q24UniSTS
RH138374  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2697,966,682 - 97,966,844 (+)MAPPERmRatBN7.2
Rnor_6.06102,343,805 - 102,343,966NCBIRnor6.0
Rnor_5.06115,030,479 - 115,030,640UniSTSRnor5.0
RGSC_v3.46101,933,737 - 101,933,898UniSTSRGSC3.4
Celera696,351,700 - 96,351,861UniSTS
RH 3.4 Map6691.6UniSTS
RH141711  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2697,961,023 - 97,961,210 (+)MAPPERmRatBN7.2
Rnor_6.06102,338,051 - 102,338,237NCBIRnor6.0
Rnor_5.06115,024,945 - 115,025,131UniSTSRnor5.0
RGSC_v3.46101,927,927 - 101,928,113UniSTSRGSC3.4
Celera696,346,176 - 96,346,362UniSTS
Cytogenetic Map6q24UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000090407   ⟹   ENSRNOP00000070613
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl697,961,346 - 97,976,300 (-)Ensembl
Rnor_6.0 Ensembl6102,339,857 - 102,353,403 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094096   ⟹   ENSRNOP00000091587
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl697,963,953 - 97,976,465 (-)Ensembl
RefSeq Acc Id: NM_001377194   ⟹   NP_001364123
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,696,135 - 103,709,487 (-)NCBI
mRatBN7.2697,963,140 - 97,976,491 (-)NCBI
RefSeq Acc Id: XM_039111590   ⟹   XP_038967518
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,694,342 - 103,709,544 (-)NCBI
mRatBN7.2697,957,700 - 97,976,486 (-)NCBI
RefSeq Acc Id: XM_039111591   ⟹   XP_038967519
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,694,342 - 103,709,468 (-)NCBI
mRatBN7.2697,957,700 - 97,976,484 (-)NCBI
RefSeq Acc Id: XM_039111592   ⟹   XP_038967520
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,694,342 - 103,709,471 (-)NCBI
mRatBN7.2697,961,346 - 97,976,488 (-)NCBI
Protein RefSeqs NP_001364123 (Get FASTA)   NCBI Sequence Viewer  
  XP_038967518 (Get FASTA)   NCBI Sequence Viewer  
  XP_038967519 (Get FASTA)   NCBI Sequence Viewer  
  XP_038967520 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000070613
  ENSRNOP00000070613.2
GenBank Protein P58200 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Acc Id: ENSRNOP00000070613   ⟸   ENSRNOT00000090407
RefSeq Acc Id: XP_038967518   ⟸   XM_039111590
- Peptide Label: isoform X1
- UniProtKB: P58200 (UniProtKB/Swiss-Prot),   A6HCG5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967519   ⟸   XM_039111591
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038967520   ⟸   XM_039111592
- Peptide Label: isoform X2
RefSeq Acc Id: NP_001364123   ⟸   NM_001377194
- UniProtKB: F1LNC4 (UniProtKB/TrEMBL),   A0A8I6GJ34 (UniProtKB/TrEMBL)
t-SNARE coiled-coil homology   Vesicle transport v-SNARE N-terminal

Name Modeler Protein Id AA Range Protein Structure
AF-P58200-F1-model_v2 AlphaFold P58200 1-232 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694695
Promoter ID:EPDNEW_R5216
Type:multiple initiation site
Name:Vti1b_1
Description:vesicle transport through interaction with t-SNAREs 1B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06102,353,411 - 102,353,471EPDNEW


1 to 26 of 26 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-36972 BioCyc
Ensembl Genes ENSRNOG00000060436 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000090407 ENTREZGENE
  ENSRNOT00000090407.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.110 UniProtKB/Swiss-Prot
  1.20.58.400 UniProtKB/Swiss-Prot
InterPro GOSR2/Membrin/Bos1 UniProtKB/Swiss-Prot
  SNARE UniProtKB/Swiss-Prot
  T_SNARE_dom UniProtKB/Swiss-Prot
  v-SNARE_N_sf UniProtKB/Swiss-Prot
  Vesicle_trsprt_v-SNARE_N UniProtKB/Swiss-Prot
NCBI Gene 100359512 ENTREZGENE
PANTHER VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1B UniProtKB/Swiss-Prot
  VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED UniProtKB/Swiss-Prot
Pfam V-SNARE UniProtKB/Swiss-Prot
  V-SNARE_C UniProtKB/Swiss-Prot
PhenoGen Vti1b PhenoGen
PIRSF Membrin-2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000060436 RatGTEx
SMART t_SNARE UniProtKB/Swiss-Prot
Superfamily-SCOP SNARE fusion complex UniProtKB/Swiss-Prot
  SSF47661 UniProtKB/Swiss-Prot
UniProt A0A8I6GJ34 ENTREZGENE, UniProtKB/TrEMBL
  A6HCG5 ENTREZGENE, UniProtKB/TrEMBL
  F1LNC4 ENTREZGENE, UniProtKB/TrEMBL
  P58200 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 26 of 26 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-13 Vti1b  vesicle transport through interaction with t-SNAREs 1B  RGD1560475  similar to vesicle transport through interaction with t-SNAREs 1B homolog  Data merged from RGD:1560475 737654 APPROVED
2015-11-13 Vti1b  vesicle transport through interaction with t-SNAREs 1B  Vti1b  vesicle transport through interaction with t-SNAREs 1B  Type changed (type changed from [null] to [protein-coding]) 629549 APPROVED
2013-08-01 Vti1b  vesicle transport through interaction with t-SNAREs 1B  LOC100359512  vesicle transport through interaction with t-SNAREs 1B-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100359512  vesicle transport through interaction with t-SNAREs 1B-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1560475  similar to vesicle transport through interaction with t-SNAREs 1B homolog   RGD1560475_predicted  similar to vesicle transport through interaction with t-SNAREs 1B homolog (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560475_predicted  similar to vesicle transport through interaction with t-SNAREs 1B homolog (predicted)  LOC366673  similar to vesicle transport through interaction with t-SNAREs 1B homolog  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC366673  similar to vesicle transport through interaction with t-SNAREs 1B homolog      Symbol and Name status set to provisional 70820 PROVISIONAL