Gle1-ps1 (GLE1 RNA export mediator, pseudogene 1) - Rat Genome Database

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Gene: Gle1-ps1 (GLE1 RNA export mediator, pseudogene 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Gle1-ps1
Name: GLE1 RNA export mediator, pseudogene 1
RGD ID: 1310843
Description: Predicted to be involved in protein transport. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome 1. Orthologous to human GLE1 (GLE1 RNA export mediator); INTERACTS WITH phenethyl isothiocyanate.
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: MODEL
Previously known as: AABR07065139.2; GLE1 RNA export mediator homolog (yeast), pseudogene 1; GLE1 RNA export mediator homolog (yeast)-like 1; Gle1l1; LOC299219; SKI interacting protein; Skiip
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Functional Gene: Gle1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86112,855,815 - 112,857,947 (-)NCBIGRCr8
mRatBN7.26107,124,892 - 107,127,024 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6107,124,892 - 107,127,024 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl6107,124,892 - 107,127,024 (-)NCBImRatBN7.2 Ensembl
Rnor_6.06111,513,052 - 111,515,175 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6111,534,548 - 111,542,338 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.06120,793,775 - 120,795,889 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46111,718,182 - 111,720,314 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16111,721,708 - 111,723,845 (-)NCBI
Celera6104,944,540 - 104,947,637 (-)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Gle1-ps1
28 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6104085867128713626Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1300076Glom8Glomerulus QTL 879e-09kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSRNOT00000087462   ⟹   ENSRNOP00000072075
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6107,124,892 - 107,127,024 (-)Ensembl
RefSeq Acc Id: XM_001059331
Type: CODING
Position: No map positions available.
RefSeq Acc Id: XM_234442
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
RGSC_v3.46111,718,182 - 111,720,314 (-)RGD
RefSeq Acc Id: XR_593191
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06111,513,054 - 111,515,175 (-)NCBI
RefSeq Acc Id: XR_601597
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera6104,944,540 - 104,946,872 (-)NCBI
Protein Sequences
Ensembl Protein ENSRNOP00000072075.2
Ensembl Acc Id: ENSRNOP00000072075   ⟸   ENSRNOT00000087462

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K222-F1-model_v2 AlphaFold A0A0G2K222 1-453 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310843 AgrOrtholog
BioCyc Gene G2FUF-36702 BioCyc
Ensembl Genes ENSRNOG00000053311 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000087462.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.510 UniProtKB/TrEMBL
InterPro GLE1 UniProtKB/TrEMBL
  GLE1-like_sf UniProtKB/TrEMBL
NCBI Gene 299219 ENTREZGENE
PANTHER NUCLEOPORIN GLE1 UniProtKB/TrEMBL
  PTHR12960 UniProtKB/TrEMBL
Pfam GLE1 UniProtKB/TrEMBL
PhenoGen Gle1-ps1 PhenoGen
RatGTEx ENSRNOG00000053311 RatGTEx
UniProt A0A0G2K222_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-13 Gle1-ps1  GLE1 RNA export mediator, pseudogene 1  Gle1-ps1  GLE1 RNA export mediator homolog (yeast), pseudogene 1  Name changed 629549 APPROVED
2022-06-02 Gle1-ps1  GLE1 RNA export mediator homolog (yeast), pseudogene 1  AABR07065139.2    Data merged from RGD:15007817 737654 PROVISIONAL
2019-11-08 AABR07065139.2        Symbol and Name status set to provisional 45752 PROVISIONAL
2011-06-08 Gle1-ps1  GLE1 RNA export mediator homolog (yeast), pseudogene 1  Gle1l1  GLE1 RNA export mediator homolog (yeast)-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Skiip  SKI interacting protein   Skiip_predicted  SKI interacting protein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Skiip_predicted  SKI interacting protein (predicted)      Symbol and Name status set to approved 70820 APPROVED