Sgpp1 (sphingosine-1-phosphate phosphatase 1) - Rat Genome Database

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Gene: Sgpp1 (sphingosine-1-phosphate phosphatase 1) Rattus norvegicus
Analyze
Symbol: Sgpp1
Name: sphingosine-1-phosphate phosphatase 1
RGD ID: 727829
Description: Predicted to enable sphingosine-1-phosphate phosphatase activity. Predicted to be involved in several processes, including ER to Golgi ceramide transport; phospholipid dephosphorylation; and sphingosine metabolic process. Predicted to act upstream of or within extrinsic apoptotic signaling pathway; intrinsic apoptotic signaling pathway; and sphinganine-1-phosphate metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human SGPP1 (sphingosine-1-phosphate phosphatase 1); PARTICIPATES IN sphingosine 1-phosphate signaling pathway; sphingolipid metabolic pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC81536; sphingosine-1-phosphatase 1; sphingosine-1-phosphate phosphohydrolase; Spp1; SPPase1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86100,161,024 - 100,182,214 (-)NCBIGRCr8
mRatBN7.2694,425,339 - 94,446,534 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl694,425,339 - 94,446,534 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx694,818,696 - 94,839,851 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0695,117,168 - 95,138,323 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0694,546,078 - 94,567,225 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0698,675,324 - 98,696,492 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl698,675,326 - 98,695,988 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06108,093,013 - 108,114,339 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4698,306,168 - 98,327,175 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1698,311,877 - 98,330,264 (-)NCBI
Celera692,851,441 - 92,872,597 (-)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-butoxyethanol  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
benzo[a]pyrene  (ISO)
bilirubin IXalpha  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
clofibric acid  (EXP)
daidzein  (ISO)
deoxynivalenol  (ISO)
diazinon  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dieldrin  (EXP)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
fenthion  (ISO)
flutamide  (EXP,ISO)
folic acid  (ISO)
FR900359  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glycitein  (ISO)
lamivudine  (ISO)
methapyrilene  (EXP)
methidathion  (ISO)
methylmercury chloride  (ISO)
monosodium L-glutamate  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nickel dichloride  (EXP)
nicotine  (ISO)
nimesulide  (EXP)
p-toluidine  (EXP)
panobinostat  (ISO)
paracetamol  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
Phenelzine  (ISO)
phenobarbital  (ISO)
picoxystrobin  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Role of sphingosine-1-phosphate phosphatase 1 in epidermal growth factor-induced chemotaxis. Le Stunff H, etal., J Biol Chem 2004 Aug 13;279(33):34290-7. Epub 2004 Jun 04.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. NCBI rat LocusLink and RefSeq merged data October 15, 2003 NCBI rat LocusLink and RefSeq merged data October 15, 2003
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10563330   PMID:10859351   PMID:11756451   PMID:12235122   PMID:15057822   PMID:15271294   PMID:16782891   PMID:23637227  


Genomics

Comparative Map Data
Sgpp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86100,161,024 - 100,182,214 (-)NCBIGRCr8
mRatBN7.2694,425,339 - 94,446,534 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl694,425,339 - 94,446,534 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx694,818,696 - 94,839,851 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0695,117,168 - 95,138,323 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0694,546,078 - 94,567,225 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0698,675,324 - 98,696,492 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl698,675,326 - 98,695,988 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06108,093,013 - 108,114,339 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4698,306,168 - 98,327,175 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1698,311,877 - 98,330,264 (-)NCBI
Celera692,851,441 - 92,872,597 (-)NCBICelera
Cytogenetic Map6q24NCBI
SGPP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381463,684,216 - 63,728,065 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1463,684,216 - 63,728,065 (-)EnsemblGRCh38hg38GRCh38
GRCh371464,150,934 - 64,194,783 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361463,220,687 - 63,264,509 (-)NCBINCBI36Build 36hg18NCBI36
Build 341463,220,688 - 63,264,509NCBI
Celera1444,201,594 - 44,245,417 (-)NCBICelera
Cytogenetic Map14q23.2NCBI
HuRef1444,317,325 - 44,361,142 (-)NCBIHuRef
CHM1_11464,089,953 - 64,133,737 (-)NCBICHM1_1
T2T-CHM13v2.01457,891,616 - 57,935,465 (-)NCBIT2T-CHM13v2.0
Sgpp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391275,761,022 - 75,782,503 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1275,761,023 - 75,782,503 (-)EnsemblGRCm39 Ensembl
GRCm381275,714,248 - 75,735,729 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1275,714,249 - 75,735,729 (-)EnsemblGRCm38mm10GRCm38
MGSCv371276,815,235 - 76,836,716 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361276,633,105 - 76,654,502 (-)NCBIMGSCv36mm8
Celera1276,819,194 - 76,840,277 (-)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1232.95NCBI
Sgpp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554666,075,507 - 6,103,739 (+)NCBIChiLan1.0ChiLan1.0
SGPP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21564,795,453 - 64,839,332 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11464,011,967 - 64,055,847 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01444,265,017 - 44,308,897 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11462,521,010 - 62,566,309 (-)NCBIpanpan1.1PanPan1.1panPan2
SGPP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1838,195,649 - 38,228,299 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl838,197,532 - 38,228,406 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha837,888,039 - 37,921,345 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0838,422,209 - 38,455,539 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl838,422,214 - 38,455,507 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1838,038,844 - 38,072,143 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0838,111,070 - 38,144,393 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0838,471,314 - 38,504,624 (-)NCBIUU_Cfam_GSD_1.0
Sgpp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864066,663,173 - 66,690,708 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364957,502,859 - 7,528,515 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364957,500,991 - 7,528,520 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SGPP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1194,352,001 - 194,380,907 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11194,351,971 - 194,380,910 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21216,298,626 - 216,383,691 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SGPP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12440,885,464 - 40,926,992 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2440,885,276 - 40,926,937 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605329,080,236 - 29,121,462 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sgpp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473437,297,806 - 37,335,553 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473437,297,954 - 37,337,830 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sgpp1
116 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:68
Count of miRNA genes:62
Interacting mature miRNAs:66
Transcripts:ENSRNOT00000006913
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)683190345106747639Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1300076Glom8Glomerulus QTL 879e-09kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat

Markers in Region
D6Rat164  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2694,449,600 - 94,449,948 (+)MAPPERmRatBN7.2
Rnor_6.0698,699,575 - 98,699,922NCBIRnor6.0
Rnor_5.06108,117,430 - 108,117,777UniSTSRnor5.0
RGSC_v3.4698,330,395 - 98,330,742UniSTSRGSC3.4
RGSC_v3.4698,330,394 - 98,330,743RGDRGSC3.4
Celera692,875,677 - 92,876,024UniSTS
RH 3.4 Map6668.4RGD
RH 3.4 Map6668.4UniSTS
SHRSP x BN Map656.7098UniSTS
SHRSP x BN Map656.7098RGD
Cytogenetic Map6q24UniSTS
AI229520  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2694,437,126 - 94,437,344 (+)MAPPERmRatBN7.2
Rnor_6.0698,687,115 - 98,687,332NCBIRnor6.0
Rnor_5.06108,104,970 - 108,105,187UniSTSRnor5.0
RGSC_v3.4698,317,932 - 98,318,149UniSTSRGSC3.4
Celera692,863,238 - 92,863,455UniSTS
RH 3.4 Map6669.1UniSTS
Cytogenetic Map6q24UniSTS
RH136984  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2694,425,377 - 94,425,576 (+)MAPPERmRatBN7.2
Rnor_6.0698,675,363 - 98,675,561NCBIRnor6.0
Rnor_5.06108,093,052 - 108,093,250UniSTSRnor5.0
RGSC_v3.4698,306,207 - 98,306,405UniSTSRGSC3.4
Celera692,851,480 - 92,851,678UniSTS
RH 3.4 Map6667.29UniSTS
Cytogenetic Map6q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 21 60 227 147 69 147 30 31 222 111 116 57 18
Low 81 6 14 28 29 6
Below cutoff

Sequence


Ensembl Acc Id: ENSRNOT00000006913   ⟹   ENSRNOP00000006913
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl694,425,339 - 94,446,534 (-)Ensembl
Rnor_6.0 Ensembl698,675,326 - 98,695,988 (-)Ensembl
RefSeq Acc Id: NM_030874   ⟹   NP_110501
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86100,161,024 - 100,182,214 (-)NCBI
mRatBN7.2694,425,339 - 94,446,534 (-)NCBI
Protein Sequences
Protein RefSeqs NP_110501 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAK07473 (Get FASTA)   NCBI Sequence Viewer  
  EDM03639 (Get FASTA)   NCBI Sequence Viewer  
  EDM03640 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000006913.7
GenBank Protein Q99P55 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Acc Id: ENSRNOP00000006913   ⟸   ENSRNOT00000006913
RefSeq Acc Id: NP_110501   ⟸   NM_030874
- UniProtKB: Q99P55 (UniProtKB/Swiss-Prot),   F1LPB0 (UniProtKB/TrEMBL),   A6HC84 (UniProtKB/TrEMBL)
Protein Domains
Phosphatidic acid phosphatase type 2/haloperoxidase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99P55-F1-model_v2 AlphaFold Q99P55 1-430 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:727829 AgrOrtholog
BioCyc Gene G2FUF-37074 BioCyc
BioCyc Pathway PWY3DJ-11470 [sphingosine and sphingosine-1-phosphate metabolism] BioCyc
BioCyc Pathway Image PWY3DJ-11470 BioCyc
Ensembl Genes ENSRNOG00000005175 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006913.7 UniProtKB/TrEMBL
Gene3D-CATH Phosphatidic acid phosphatase type 2/haloperoxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro P_Acid_Pase_2/haloperoxi_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P_Acid_Pase_2/haloperoxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 81536 ENTREZGENE
PANTHER SPHINGOSINE-1-PHOSPHATE PHOSPHATASE 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PAP2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sgpp1 PhenoGen
RatGTEx ENSRNOG00000005175 RatGTEx
SMART acidPPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48317 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6HC84 ENTREZGENE, UniProtKB/TrEMBL
  A6HC85_RAT UniProtKB/TrEMBL
  F1LPB0 ENTREZGENE, UniProtKB/TrEMBL
  Q99P55 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-04-22 Sgpp1  sphingosine-1-phosphate phosphatase 1  LOC81536  sphingosine-1-phosphate phosphohydrolase  Symbol and Name updated to reflect Human and Mouse nomenclature 625702 APPROVED