Psma3 (proteasome 20S subunit alpha 3)

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Gene: Psma3 (proteasome 20S subunit alpha 3) Rattus norvegicus

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Symbol:

Psma3

Name:

proteasome 20S subunit alpha 3

RGD ID:

61844

Description:

Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and regulation of endopeptidase activity. Predicted to be part of proteasome core complex, alpha-subunit complex. Predicted to be active in cytoplasm; nucleus; and synapse. Orthologous to human PSMA3 (proteasome 20S subunit alpha 3); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 1,3-dinitrobenzene; 2,4-dibromophenyl 2,4,5-tribromophenyl ether.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

macropain subunit C8; multicatalytic endopeptidase complex subunit C8; multicatalytic proteinase subunit K; proteasome (prosome, macropain) subunit, alpha type 3; proteasome component C8; proteasome subunit alpha 3; proteasome subunit alpha type 3-like; proteasome subunit alpha type-3; proteasome subunit C8; proteasome subunit K; Psma3l

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PSMA3 (proteasome 20S subunit alpha 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Psma3 (proteasome subunit alpha 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Psma3 (proteasome 20S subunit alpha 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PSMA3 (proteasome 20S subunit alpha 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PSMA3 (proteasome 20S subunit alpha 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Psma3 (proteasome 20S subunit alpha 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PSMA3 (proteasome 20S subunit alpha 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PSMA3 (proteasome 20S subunit alpha 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Psma3 (proteasome 20S subunit alpha 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Psma3 (proteasome subunit alpha 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PSMA3 (proteasome 20S subunit alpha 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	psma3 (proteasome subunit alpha 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PRE10	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Prosalpha7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	pas-7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	psma3	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	95,219,714 - 95,239,745 (+)	NCBI		GRCr8
mRatBN7.2	6	89,483,741 - 89,503,775 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	89,483,727 - 89,504,965 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	89,868,034 - 89,888,332 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	90,167,503 - 90,187,803 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	89,606,993 - 89,627,292 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	93,423,029 - 93,444,223 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	93,423,002 - 93,444,240 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	102,868,534 - 102,898,751 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	93,092,191 - 93,112,167 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	93,095,646 - 93,115,622 (+)	NCBI
Celera	6	87,965,854 - 87,985,832 (+)	NCBI		Celera
Cytogenetic Map	6	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Joubert syndrome 23 (ISO)

proteasome-associated autoinflammatory syndrome 1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trimethylbenzene (EXP)

1,2-dimethylhydrazine (ISO)

1,3-dinitrobenzene (EXP)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (EXP)

2,5-hexanedione (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

amitrole (EXP)

ammonium chloride (EXP)

ampicillin (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

bis(2-chloroethyl) sulfide (EXP)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (EXP,ISO)

bromobenzene (EXP)

bufalin (ISO)

caffeine (ISO)

clofibrate (ISO)

cobalt dichloride (EXP)

cyclosporin A (ISO)

dibenzo[a,l]pyrene (ISO)

dibutyl phthalate (EXP)

dichlorine (EXP)

dicrotophos (ISO)

dimethylarsinous acid (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

ethanol (ISO)

finasteride (EXP)

fluoxetine (EXP)

flutamide (EXP)

folic acid (ISO)

FR900359 (ISO)

genistein (EXP,ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

isotretinoin (ISO)

ivermectin (ISO)

lovastatin (ISO)

methidathion (ISO)

methimazole (EXP)

methoxychlor (EXP)

metronidazole (EXP)

monocrotaline (EXP)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

nefazodone (EXP)

neomycin (EXP)

nickel atom (ISO)

nickel subsulfide (ISO)

nimesulide (EXP)

ozone (EXP,ISO)

p-menthan-3-ol (ISO)

paracetamol (EXP,ISO)

Pentoxifylline (EXP)

perfluorohexanesulfonic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

phenethyl isothiocyanate (ISO)

phenobarbital (EXP)

picrotoxin (EXP)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

quinoline (ISO)

resveratrol (ISO)

rotenone (EXP,ISO)

sarin (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

titanium dioxide (ISO)

Tributyltin oxide (ISO)

tungsten (ISO)

valdecoxib (EXP)

vancomycin (EXP)

vorinostat (ISO)

warfarin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

proteasome-mediated ubiquitin-dependent protein catabolic process (IBA)

regulation of endopeptidase activity (ISO)

ubiquitin-dependent protein catabolic process (IEA)

Cellular Component

cytoplasm (IEA,ISO)

nucleus (IBA,IEA,ISO)

proteasome complex (ISO)

proteasome core complex (ISO,ISS)

proteasome core complex, alpha-subunit complex (IBA,IEA,ISS)

synapse (IBA)

Molecular Function

protein binding (ISO)

ubiquitin protein ligase binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

ubiquitin/proteasome degradation pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Activity-dependent dynamics and sequestration of proteasomes in dendritic spines.	Bingol B and Schuman EM, Nature. 2006 Jun 29;441(7097):1144-8.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
7.	A genomic analysis of rat proteases and protease inhibitors.	Puente XS and Lopez-Otin C, Genome Res 2004 Apr;14(4):609-22.
8.	GOA pipeline	RGD automated data pipeline
9.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
11.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
12.	cDNA cloning and sequencing of component C8 of proteasomes from rat hepatoma cells.	Tanaka K, etal., Biochem Biophys Res Commun 1990 Sep 14;171(2):676-83.
13.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data

Additional References at PubMed

PMID:2249692	PMID:2335242	PMID:9688553	PMID:15489334	PMID:16207813	PMID:16641100	PMID:16857966	PMID:17323924	PMID:19056867	PMID:19208651	PMID:20458337	PMID:20498273
PMID:21630459	PMID:22793692	PMID:23376485	PMID:25002582	PMID:26524591	PMID:30361391	PMID:31904090

Genomics

Comparative Map Data

Psma3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	95,219,714 - 95,239,745 (+)	NCBI		GRCr8
mRatBN7.2	6	89,483,741 - 89,503,775 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	89,483,727 - 89,504,965 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	89,868,034 - 89,888,332 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	90,167,503 - 90,187,803 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	89,606,993 - 89,627,292 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	93,423,029 - 93,444,223 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	93,423,002 - 93,444,240 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	102,868,534 - 102,898,751 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	93,092,191 - 93,112,167 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	93,095,646 - 93,115,622 (+)	NCBI
Celera	6	87,965,854 - 87,985,832 (+)	NCBI		Celera
Cytogenetic Map	6	q24	NCBI

PSMA3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	58,244,843 - 58,272,004 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	58,244,843 - 58,272,012 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	58,711,561 - 58,738,722 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	57,781,346 - 57,808,479 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	57,781,345 - 57,808,479	NCBI
Celera	14	38,761,540 - 38,788,685 (+)	NCBI		Celera
Cytogenetic Map	14	q23.1	NCBI
HuRef	14	38,877,058 - 38,904,216 (+)	NCBI		HuRef
CHM1_1	14	58,650,049 - 58,677,295 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	52,451,770 - 52,478,987 (+)	NCBI		T2T-CHM13v2.0

Psma3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	71,016,082 - 71,042,651 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	71,021,395 - 71,043,121 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	70,969,283 - 70,995,877 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	70,974,621 - 70,996,347 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	72,075,610 - 72,095,924 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	71,893,298 - 71,913,526 (+)	NCBI		MGSCv36	mm8
Celera	12	72,078,082 - 72,098,500 (+)	NCBI		Celera
Cytogenetic Map	12	C2	NCBI
cM Map	12	29.39	NCBI

Psma3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955466	11,979,482 - 11,997,952 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955466	11,979,482 - 11,997,952 (+)	NCBI	ChiLan1.0	ChiLan1.0

PSMA3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	59,364,546 - 59,394,007 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	58,583,210 - 58,610,522 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	38,836,869 - 38,864,152 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	57,105,891 - 57,133,181 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	57,105,891 - 57,133,181 (+)	Ensembl	panpan1.1		panPan2

PSMA3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	33,616,735 - 33,642,434 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	33,616,480 - 33,642,404 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	33,378,219 - 33,403,729 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	33,858,343 - 33,884,028 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	33,858,385 - 33,884,037 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	33,471,278 - 33,496,743 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	33,538,435 - 33,564,256 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	33,913,572 - 33,939,074 (+)	NCBI		UU_Cfam_GSD_1.0

Psma3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	71,519,504 - 71,541,053 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936495	2,650,629 - 2,673,435 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936495	2,650,668 - 2,672,192 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PSMA3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	187,343,507 - 187,372,193 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	187,342,231 - 187,371,149 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	208,246,764 - 208,274,223 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PSMA3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	35,438,084 - 35,465,320 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	35,437,308 - 35,465,203 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	23,674,689 - 23,701,992 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Psma3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624884	3,324,418 - 3,346,128 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624884	3,324,390 - 3,346,128 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Psma3
114 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	152
Count of miRNA genes:	102
Interacting mature miRNAs:	124
Transcripts:	ENSRNOT00000010753
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	72202632	130919985	Rat
634330	Pia16	Pristane induced arthritis QTL 16	3.9		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	6	45790088	104200226	Rat
1331789	Rf37	Renal function QTL 37	3.224		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	6	72202632	115200186	Rat
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	10894415	110548006	Rat
70176	Mcsm1	Mammary carcinoma susceptibility modifier QTL 1			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	58632962	103632962	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	72227641	130729205	Rat
10054138	Gmadr3	Adrenal mass QTL 3	3.68	0.00045	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	6	85140138	130140138	Rat
1558641	Cm47	Cardiac mass QTL 47	2.9	0.001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	6	57730540	104085867	Rat
724524	Uae2	Urinary albumin excretion QTL 2	2.7	0.0005	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	73463459	109394713	Rat
737827	Hcar11	Hepatocarcinoma resistance QTL 11	4.4		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	6	82523650	110548006	Rat
1641904	Alcrsp4	Alcohol response QTL 4			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	6	67262953	112262953	Rat
724513	Uae14	Urinary albumin excretion QTL 14	6.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	85311061	133478515	Rat
2303624	Vencon5	Ventilatory control QTL 5	4.45		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	6	88047916	133047916	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	15107216	107351382	Rat
731173	Uae22	Urinary albumin excretion QTL 22	10.1		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
2293837	Kiddil1	Kidney dilation QTL 1	3.7		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	81132889	104393926	Rat
2293842	Kiddil3	Kidney dilation QTL 3	4.3		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	81132889	104393926	Rat
4889848	Pur25	Proteinuria QTL 25	14	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	56728562	90198260	Rat
10054123	Srcrt6	Stress Responsive Cort QTL 6	2.5	0.0043	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	85140138	130140138	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	72202632	130729475	Rat
70196	BpQTLcluster7	Blood pressure QTL cluster 7	6.82		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	72202632	117202632	Rat
1581550	Pur8	Proteinuria QTL 8			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	72227641	130729205	Rat
1576302	Schws4	Schwannoma susceptibility QTL 4		0.0078	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	83190345	106747639	Rat
1300075	Glom7	Glomerulus QTL 7	5.6	0.0000002	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	6	71201409	116201409	Rat
738034	Anxrr5	Anxiety related response QTL 5	5.9		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	6	84130881	129130881	Rat
2290393	Uae37	Urinary albumin excretion QTL 37		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
12801471	Schws9	Schwannoma susceptibility QTL 9			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	61747639	106747639	Rat
6893332	Cm74	Cardiac mass QTL 74	0.4	0.64	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	57730540	104085867	Rat
1300076	Glom8	Glomerulus QTL 8	7	9e-09	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	6	86894788	131894788	Rat

Markers in Region

RH127444

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	89,503,492 - 89,503,708 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	93,442,743 - 93,442,958	NCBI	Rnor6.0
Rnor_5.0	6	102,898,469 - 102,898,684	UniSTS	Rnor5.0
RGSC_v3.4	6	93,111,885 - 93,112,100	UniSTS	RGSC3.4
Celera	6	87,985,550 - 87,985,765	UniSTS
RH 3.4 Map	6	639.3	UniSTS
Cytogenetic Map	6	q24	UniSTS

RH138090

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	89,485,444 - 89,485,591 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	93,424,697 - 93,424,843	NCBI	Rnor6.0
Rnor_5.0	6	102,870,438 - 102,870,584	UniSTS	Rnor5.0
RGSC_v3.4	6	93,093,859 - 93,094,005	UniSTS	RGSC3.4
Celera	6	87,967,522 - 87,967,668	UniSTS
RH 3.4 Map	6	640.3	UniSTS
Cytogenetic Map	10	q25	UniSTS
Cytogenetic Map	6	q24	UniSTS

RH130667

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	89,504,584 - 89,504,785 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	93,443,835 - 93,444,035	NCBI	Rnor6.0
Rnor_5.0	6	102,899,561 - 102,899,761	UniSTS	Rnor5.0
RGSC_v3.4	6	93,112,977 - 93,113,177	UniSTS	RGSC3.4
Celera	6	87,986,642 - 87,986,842	UniSTS
RH 3.4 Map	6	639.5	UniSTS
Cytogenetic Map	6	q24	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_017280	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261592	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261593	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC128303	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC081817	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ211111	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ219582	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222497	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ224319	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227243	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ233787	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000010753 ⟹ ENSRNOP00000010753

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	89,484,684 - 89,501,189 (+)	Ensembl
Rnor_6.0 Ensembl	6	93,423,002 - 93,444,240 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000075868

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	6	93,437,383 - 93,441,873 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000105733 ⟹ ENSRNOP00000084525

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	89,483,740 - 89,504,965 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114457 ⟹ ENSRNOP00000094706

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	89,483,727 - 89,503,086 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119219 ⟹ ENSRNOP00000096724

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	89,484,684 - 89,501,189 (+)	Ensembl

RefSeq Acc Id:

NM_017280 ⟹ NP_058976

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	95,219,749 - 95,239,745 (+)	NCBI
mRatBN7.2	6	89,483,777 - 89,503,775 (+)	NCBI
Rnor_6.0	6	93,423,029 - 93,443,025 (+)	NCBI
Rnor_5.0	6	102,868,534 - 102,898,751 (+)	NCBI
RGSC_v3.4	6	93,092,191 - 93,112,167 (+)	RGD
Celera	6	87,965,854 - 87,985,832 (+)	RGD

Sequence:

show sequence

CCATGAGCTCCATTGGCACTGGGTATGACCTGTCAGCCTCTACATTCTCTCCTGATGGAAGAGT
TTTCCAAGTTGAATATGCTATGAAGGCTGTGGAAAACAGTAGTACAGCTATTGGGATCAGATGT
AAAGATGGTGTTGTGTTTGGGGTAGAAAAACTAGTCCTTTCTAAACTTTATGAAGAAGGCTCCA
ATAAACGTCTTTTCAATGTTGATCGACATGTTGGAATGGCAGTGGCAGGTTTGTTGGCAGATGC
TCGTTCCTTGGCAGACATAGCAAGAGAAGAAGCGTCCAACTTTAGGTCTAACTTTGGCTATAAC
ATTCCTCTAAAACATCTTGCAGACAGAGTGGCCATGTATGTACACGCGTATACACTCTACAGTG
CTGTTAGACCTTTTGGCTGCAGTTTCATGTTGGGGTCTTACAGTGTGAATGATGGTGCACAGCT
CTATATGATCGATCCATCAGGTGTTTCATATGGTTACTGGGGCTGTGCCATTGGCAAAGCCAGG
CAAGCTGCAAAGACAGAAATAGAAAAGCTTCAGATGAAGGAAATGACCTGCCGTGATGTAGTTA
AAGAAGTTGCAAAAATAATTTACATAGTACATGATGAAGTTAAGGATAAAGCTTTTGAACTAGA
GCTCAGCTGGGTTGGTGAATTAACTAAAGGAAGACATGAAATTGTTCCCAAAGACGTAAGAGAG
GAAGCAGAGAAATATGCCAAGGAATCTTTGAAGGAAGAAGATGAATCAGATGACGACAATATGT
AACATTTCACCATCCTCTGGTGTCCATTTCTGTGACAGTTGCATATGGCTAGCACCATGGATTA
TATATACCCACTGACCAATTTTCATTAAATTTTGTCTTATAAACATTGTTGGGTAATTGAGGAT
ATCTGCGTTATATTAAAATGTAGATTCATGTTTGATTAGAAATTCTAGGAACTGGGCCTGGAGA
GATGGCTCAGCAGTTAAGAGCTGCTCTTCCAGGGGACATAGGTTCAATTCCCAGCACCCGCATG
GCAGCTCACACCTGTTTGTAACTCTAGCTCCAGGTCTCTGACACCTAGACACAGAGGTACTTGC
AGGCAAAACACCAATGAATATAAAATAAAAATAAATGATATATATATTTACACATATAACAAGT
ATATACAAATATGTATATTATACAGACACATGTGTGTGTATATACATATAAATTCTTGGTGCTA
TTCTGGTGTGGTAGTATATGTCTTTAATCCTAGTACTCTGGAGGCAGAGGCAGGTGGATCTCTT
GAGTTCAAGGCTAGTATTTAAAAACAAAAACAAATGTAGTGCCCAGACTAAGGCTGAAAGATTG
AGCCCACAAGTCAATTTACAATTCCATTTTGTTTTAACTAGAATTAAAAGAATAATTTTAGATT
TTTTTTTTCTTTTTTTCAGAGCTGGGGACCGAACCCAGGGCCTTGCGCTTCCTAGGCAAGCGCT
CTACCACTAAGCTAAATCCCCAACCCCTTAGATTTATTTTTATTTTTTGCATGTTTATGTATAT
TACAGTGCCATGCCTGGTGCTCATGGAGGTCAAAAGAATGCTTTAATCTAGAACTAAAGTTATG
GAGGACTGTGAATCATGTATGTTCGAAACTGAACTTGGGTCCTGTGTAAGAGCAACACGTCCTC
TTAACCACTGAGCCATCTCTCCAGCCCTCTTTGACTAGAATGATCATATTCTACTGTGGTTCTT
GTATAATGTTTTGTTTAATGTAGGGATATCCTGTAACCACTATTGAGGACTAACCTGCCTTTTG
TGGAAAATGTGACATATTCTAATTTGACATCAATACAGACAACATTTATTTTCAGACTGCATAA
ATATCTTATGACTGGAAATTATCTTGATATTGGCACCTGAAACAAAAACTTAAAAGTTCCAAAC
TGGGCTTAAATATTTCATGTAATAAAATGTTTATAGTACTTATCTGAAAAAAAAAAAAAAAAAA
AAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_017594059 ⟹ XP_017449548

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	95,219,714 - 95,238,653 (+)	NCBI
mRatBN7.2	6	89,483,741 - 89,502,746 (+)	NCBI
Rnor_6.0	6	93,424,370 - 93,444,223 (+)	NCBI

Sequence:

show sequence

GTATGACCTGTCAGCCTCTACATTCTCTCCTGATGGAAGAGTTTTCCAAGTTGAATATGCTATG
AAGGCTGTGGAAAACAGTAGCTATTGGGATCAGATGTAAAGATGGTGTTGTGTTTGGGGTAGAA
AAACTAGTCCTTTCTAAACTTTATGAAGAAGGCTCCAATAAACGTCTTTTCAATGTTGATCGAC
ATGTTGGAATGGCAGTGGCAGGTTTGTTGGCAGATGCTCGTTCCTTGGCAGACATAGCAAGAGA
AGAAGCGTCCAACTTTAGGTCTAACTTTGGCTATAACATTCCTCTAAAACATCTTGCAGACAGA
GTGGCCATGTATGTACACGCGTATACACTCTACAGTGCTGTTAGACCTTTTGGCTGCAGTTTCA
TGTTGGGGTCTTACAGTGTGAATGATGGTGCACAGCTCTATATGATCGATCCATCAGGTGTTTC
ATATGGTTACTGGGGCTGTGCCATTGGCAAAGCCAGGCAAGCTGCAAAGACAGAAATAGAAAAG
CTTCAGATGAAGGAAATGACCTGCCGTGATGTAGTTAAAGAAGTTGCAAAAATAATTTACATAG
TACATGATGAAGTTAAGGATAAAGCTTTTGAACTAGAGCTCAGCTGGGTTGGTGAATTAACTAA
AGGAAGACATGAAATTGTTCCCAAAGACGTAAGAGAGGAAGCAGAGAAATATGCCAAGGAATCT
TTGAAGGAAGAAGATGAATCAGATGACGACAATATGTAACATTTCACCATCCTCTGGTGTCCAT
TTCTGTGACAGTTGCATATGGCTAGCACCATGGATTATATATACCCACTGACCAATTTTCATTA
AATTTTGTCTTATAAACATTGTTGGGTAATTGAGGATATCTGCGTTATATTAAAATGTAGATTC
ATGTTTGATTAGAAATTCTAGGAACTGGGCCTGGAGAGATGGCTCAGCAGTTAAGAGCTGCTCT
TCCAGGGGACATAGGTTCAATTCCCAGCACCCGCATGGCAGCTCACACCTGTTTGTAACTCTAG
CTCCAGGTCTCTGACACCTAGACACAGAGGTACTTGCAGGCAAAACACCAATGAATATAAAATA
AAAATAAATGATATATATATTTACACATATAACAAGTATATACAAATATGTATATTATACAGAC
ACATGTGTGTGTATATACATATAAATTCTTGGTGCTATTCTGGTGTGGTAGTATATGTCTTTAA
TCCTAGTACTCTGGAGGCAGAGGCAGGTGGATCTCTTGAGTTCAAGGCTAGTATTTAAAAACAA
AAACAAATGTAGTGCCCAGACTAAGGCTGAAAGATTGAGCCCACAAGTCAATTTACAATTCCAT
TTTGTTTTAACTAGAATTAAAAGAATAATTTTAGATTTTTTTTTTCTTTTTTTCAGAGCTGGGG
ACCGAACCCAGGGCCTTGCGCTTCCTAGGCAAGCGCTCTACCACTAAGCTAAATCCCCAACCCC
TTAGATTTATTTTTATTTTTTGCATGTTTATGTATATTACAGTGCCATGCCTGGTGCTCATGGA
GGTCAAAAGAATGCTTTAATCTAGAACTAAAGTTATGGAGGACTGTGAATCATGTATGTTCGAA
ACTGAACTTGGGTCCTGTGTAAGAGCAACACGTCCTCTTAACCACTGAGCCATCTCTCCAGCCC
TCTTTGACTAGAATGATCATATTCTACTGTGGTTCTTGTATAATGTTTTGTTTAATGTAGGGAT
ATCCTGTAACCACTATTGAGGACTAACCTGCCTTTTGTGGAAAATGTGACATATTCTAATTTGA
CATCAATACAGACAACATTTATTTTCAGACTGCATAAATATCTTATGACTGGAAATTATCTTGA
TATTGGCACCTGAAACAAAAACTTAAAAGTTCCAAACTGGGCTTAAATATTTCATGTAATAAAA
TGTTTATAGTACTTATCTGATAAGAAAGAGTTCTTTTGGTTTGTTTCTGTTACTTTTGGTTTAT
CTGAGGCAGAGTTAGTCTTCCTACATAAGCCCTGCCTGTCCTGGAACTTATTACATAGGCCAGG
CTGGCTTTGAACTCTCGAGATCCCCTTGCCTCTGCCTCCACCACACCTGGCCCTGTTTCTGTTG
TTAAAATGACCTAAAAAAAAGAAAATCAAATTTAGATTGTCAGTATCTCTGAAACAATTTCCTT
TGTAAGACAAGTGGCAAAATTAAAATTATGTATATTTTTTAAACATAAAGTAAACACATACTAC
AATGCAGATAAGATACCAGAAGAAACTCCAAATGAAAACGTCTTGAATGTGTAACTTTCTGTTT
TATTCGTCTGTTGAAATGTAATCTAGAGCTGACCTATATTTTACATTCTGGAACATCGCTGTAT
CCATATTGTATTCCTCGTACTTAGGCTGTTTCTAAGAGGAAGACAGTCCTATGTATTCCCCACA
AAGCCACCATAAGATCTCAAAACCACCAAAGTTCCTCCCCACTAAAGGCCCTTCAAGTGTTTAA
TATTTTTATCATAAATTATGTTTGTAACTAACCATGTGCAGTTCCACCACCCAGAACATGAGTT
GTTTTAAATCAGACAAGGCATGGTGCCACATACATTGTAATTCTAGTTCTCTAGAAGGTAAGAT
AGGAGAATTTAGAGGTCAACTTTGGATAAGGAGTGAGTGAGTTTCAGGCAAATCTGGAGAATCT
TACTTAACAAGAAGCTTCTTATAGGTATATCTGTGAGTTCTAGGACACCCTGGCCTATAAAGTT
AGTTCCAAGACAGGCAGGGCTACACAAAAGAAACTCTGTTTCAAAAAAACAAAAATACACGTCT
AATTCAACTTCAGTTGCCTAACAACTGTCAAAGCATGCAAGATTAAAGACAGAAAATAGAAACC
GATTCTTACCCTTTATAAAATACTCTGAAAACCCCATAGTGATGAAACTGCTAGTTGCTATCTT
GCTCCCTATAATCTGACTACTTTTCAAGAGTTACAGGGCAAAAGGCATTCATTCTCATAACCCA
AGATGTTTTACCGTCTATTTATATCCACTGTCTATTCAGCTTGAACTGTGTTACACAATAGGTA
ACTGTATTTATTGTGCTTTGTATATTTGAACATTAAAATGTTCTTTTTTGATCATTTACCCTTG
AA

hide sequence

RefSeq Acc Id:

XM_063261592 ⟹ XP_063117662

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	95,220,008 - 95,238,653 (+)	NCBI

RefSeq Acc Id:

XM_063261593 ⟹ XP_063117663

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	95,219,900 - 95,238,653 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_058976	(Get FASTA)	NCBI Sequence Viewer
	XP_017449548	(Get FASTA)	NCBI Sequence Viewer
	XP_063117662	(Get FASTA)	NCBI Sequence Viewer
	XP_063117663	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH81817	(Get FASTA)	NCBI Sequence Viewer
	EDM03560	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000010753.5
	ENSRNOP00000084525.1
	ENSRNOP00000094706.1
	ENSRNOP00000096724.1
	ENSRNOP00055012856
	ENSRNOP00060008290
	ENSRNOP00065008217
GenBank Protein	P18422	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_058976 ⟸ NM_017280

- UniProtKB:

P18422 (UniProtKB/Swiss-Prot), A6HC06 (UniProtKB/TrEMBL), Q6IE67 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSN
KRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSA
VRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTCRDVVK
EVAKIIYIVHDEVKDKAFELELSWVGELTKGRHEIVPKDVREEAEKYAKESLKEEDESDDDNM

hide sequence

RefSeq Acc Id:	XP_017449548 ⟸ XM_017594059
- Peptide Label:	isoform X2
- Sequence:	show sequence MAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLG SYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTCRDVVKEVAKIIYIVHD EVKDKAFELELSWVGELTKGRHEIVPKDVREEAEKYAKESLKEEDESDDDNM hide sequence

Ensembl Acc Id:

ENSRNOP00000010753 ⟸ ENSRNOT00000010753

Ensembl Acc Id:

ENSRNOP00000084525 ⟸ ENSRNOT00000105733

Ensembl Acc Id:

ENSRNOP00000094706 ⟸ ENSRNOT00000114457

Ensembl Acc Id:

ENSRNOP00000096724 ⟸ ENSRNOT00000119219

RefSeq Acc Id:	XP_063117663 ⟸ XM_063261593
- Peptide Label:	isoform X3
- UniProtKB:	A6HH67 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063117662 ⟸ XM_063261592
- Peptide Label:	isoform X1
- UniProtKB:	Q6IE67 (UniProtKB/TrEMBL)

Protein Domains

Proteasome alpha-type subunits

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P18422-F1-model_v2	AlphaFold	P18422	1-255	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694647

Promoter ID:

EPDNEW_R5170

Type:

initiation region

Name:

Psma3_1

Description:

proteasome subunit alpha 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	93,422,967 - 93,423,027	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:61844	AgrOrtholog
BioCyc Gene	G2FUF-37187	BioCyc
Ensembl Genes	ENSRNOG00000007851	Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00055009458	UniProtKB/Swiss-Prot
	ENSRNOG00060006748	UniProtKB/Swiss-Prot
	ENSRNOG00065007205	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000010753.7	UniProtKB/TrEMBL
	ENSRNOT00000105733.1	UniProtKB/Swiss-Prot
	ENSRNOT00000114457.1	UniProtKB/TrEMBL
	ENSRNOT00000119219.1	UniProtKB/TrEMBL
	ENSRNOT00055016021	UniProtKB/Swiss-Prot
	ENSRNOT00060011098	UniProtKB/Swiss-Prot
	ENSRNOT00065011258	UniProtKB/Swiss-Prot
Gene3D-CATH	3.60.20.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7110009	IMAGE-MGC_LOAD
InterPro	Ntn_hydrolases_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Proteasome_alpha	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Proteasome_alpha-type	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Proteasome_asu_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Proteasome_sua/b	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:29670	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:93511	IMAGE-MGC_LOAD
NCBI Gene	29670	ENTREZGENE
PANTHER	PROTEASOME SUBUNIT ALPHA/BETA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR11599:SF10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Proteasome	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Proteasome_A_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Psma3	PhenoGen
PROSITE	PROTEASOME_ALPHA_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEASOME_ALPHA_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000007851	RatGTEx
	ENSRNOG00055009458	RatGTEx
	ENSRNOG00060006748	RatGTEx
	ENSRNOG00065007205	RatGTEx
SMART	Proteasome_A_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF56235	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR	TC216589
UniProt	A0A8I6AVH8_RAT	UniProtKB/TrEMBL
	A0A8I6B1E1_RAT	UniProtKB/TrEMBL
	A0A8L2Q4S0_RAT	UniProtKB/TrEMBL
	A6HC06	ENTREZGENE, UniProtKB/TrEMBL
	A6HH67	ENTREZGENE, UniProtKB/TrEMBL
	P18422	ENTREZGENE, UniProtKB/Swiss-Prot
	Q6IE67	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-09-13	Psma3	proteasome 20S subunit alpha 3	Psma3	proteasome subunit alpha 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-08-19	Psma3	proteasome subunit alpha 3	Psma3	proteasome (prosome, macropain) subunit, alpha type 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Psma3	proteasome (prosome, macropain) subunit, alpha type 3			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)