Psma3 (proteasome 20S subunit alpha 3) - Rat Genome Database

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Gene: Psma3 (proteasome 20S subunit alpha 3) Rattus norvegicus
Analyze
Symbol: Psma3
Name: proteasome 20S subunit alpha 3
RGD ID: 61844
Description: Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in proteasomal protein catabolic process and regulation of endopeptidase activity. Located in synapse. Orthologous to human PSMA3 (proteasome 20S subunit alpha 3); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 1,3-dinitrobenzene; 2,4-dibromophenyl 2,4,5-tribromophenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: macropain subunit C8; multicatalytic endopeptidase complex subunit C8; multicatalytic proteinase subunit K; proteasome (prosome, macropain) subunit, alpha type 3; proteasome component C8; proteasome subunit alpha 3; proteasome subunit alpha type 3-like; proteasome subunit alpha type-3; proteasome subunit C8; proteasome subunit K; Psma3l
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2689,483,741 - 89,503,775 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl689,483,727 - 89,504,965 (+)Ensembl
Rnor_6.0693,423,029 - 93,444,223 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl693,423,002 - 93,444,240 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06102,868,534 - 102,898,751 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4693,092,191 - 93,112,167 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1693,095,646 - 93,115,622 (+)NCBI
Celera687,965,854 - 87,985,832 (+)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trimethylbenzene  (EXP)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
ampicillin  (EXP)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
bromobenzene  (EXP)
bufalin  (ISO)
clofibrate  (ISO)
cyclosporin A  (ISO)
dibenzo[a,l]pyrene  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
dimethylarsinous acid  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
finasteride  (EXP)
fluoxetine  (EXP)
flutamide  (EXP)
folic acid  (ISO)
genistein  (EXP,ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
lovastatin  (ISO)
methidathion  (ISO)
methoxychlor  (EXP)
metronidazole  (EXP)
monocrotaline  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
nefazodone  (EXP)
neomycin  (EXP)
nickel atom  (ISO)
nickel subsulfide  (ISO)
nimesulide  (EXP)
ozone  (ISO)
p-menthan-3-ol  (ISO)
paracetamol  (EXP,ISO)
Pentoxifylline  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP)
picrotoxin  (EXP)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
quinoline  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
sarin  (ISO)
sunitinib  (ISO)
Tributyltin oxide  (ISO)
tungsten  (ISO)
valdecoxib  (EXP)
vancomycin  (EXP)
vorinostat  (ISO)
warfarin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Activity-dependent dynamics and sequestration of proteasomes in dendritic spines. Bingol B and Schuman EM, Nature. 2006 Jun 29;441(7097):1144-8.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. A genomic analysis of rat proteases and protease inhibitors. Puente XS and Lopez-Otin C, Genome Res 2004 Apr;14(4):609-22.
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
12. cDNA cloning and sequencing of component C8 of proteasomes from rat hepatoma cells. Tanaka K, etal., Biochem Biophys Res Commun 1990 Sep 14;171(2):676-83.
13. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:2249692   PMID:2335242   PMID:9688553   PMID:15489334   PMID:16207813   PMID:16641100   PMID:16857966   PMID:17323924   PMID:19056867   PMID:19208651   PMID:20458337   PMID:20498273  
PMID:21630459   PMID:22793692   PMID:23376485   PMID:25002582   PMID:26524591   PMID:30361391   PMID:31904090  


Genomics

Comparative Map Data
Psma3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2689,483,741 - 89,503,775 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl689,483,727 - 89,504,965 (+)Ensembl
Rnor_6.0693,423,029 - 93,444,223 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl693,423,002 - 93,444,240 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06102,868,534 - 102,898,751 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4693,092,191 - 93,112,167 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1693,095,646 - 93,115,622 (+)NCBI
Celera687,965,854 - 87,985,832 (+)NCBICelera
Cytogenetic Map6q24NCBI
PSMA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381458,244,843 - 58,272,004 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1458,244,843 - 58,272,012 (+)EnsemblGRCh38hg38GRCh38
GRCh371458,711,561 - 58,738,722 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361457,781,346 - 57,808,479 (+)NCBINCBI36hg18NCBI36
Build 341457,781,345 - 57,808,479NCBI
Celera1438,761,540 - 38,788,685 (+)NCBI
Cytogenetic Map14q23.1NCBI
HuRef1438,877,058 - 38,904,216 (+)NCBIHuRef
CHM1_11458,650,049 - 58,677,295 (+)NCBICHM1_1
T2T-CHM13v2.01452,451,770 - 52,478,987 (+)NCBI
Psma3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391271,016,057 - 71,042,651 (+)NCBIGRCm39mm39
GRCm39 Ensembl1271,021,395 - 71,043,121 (+)Ensembl
GRCm381270,969,283 - 70,995,877 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1270,974,621 - 70,996,347 (+)EnsemblGRCm38mm10GRCm38
MGSCv371272,075,610 - 72,095,924 (+)NCBIGRCm37mm9NCBIm37
MGSCv361271,893,298 - 71,913,526 (+)NCBImm8
Celera1272,078,082 - 72,098,500 (+)NCBICelera
Cytogenetic Map12C2NCBI
Psma3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546611,979,482 - 11,997,952 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546611,979,482 - 11,997,952 (+)NCBIChiLan1.0ChiLan1.0
PSMA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11457,105,891 - 57,133,181 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1457,105,891 - 57,133,181 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01438,836,869 - 38,864,152 (+)NCBIMhudiblu_PPA_v0panPan3
PSMA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1833,616,735 - 33,642,434 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl833,616,480 - 33,642,404 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha833,378,219 - 33,403,729 (+)NCBI
ROS_Cfam_1.0833,858,343 - 33,884,028 (+)NCBI
ROS_Cfam_1.0 Ensembl833,858,385 - 33,884,037 (+)Ensembl
UMICH_Zoey_3.1833,471,278 - 33,496,743 (+)NCBI
UNSW_CanFamBas_1.0833,538,435 - 33,564,256 (+)NCBI
UU_Cfam_GSD_1.0833,913,572 - 33,939,074 (+)NCBI
Psma3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864071,519,504 - 71,541,053 (-)NCBI
SpeTri2.0NW_0049364952,650,668 - 2,672,192 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PSMA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1187,343,507 - 187,372,215 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11187,342,231 - 187,371,149 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21208,246,764 - 208,274,223 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PSMA3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12435,438,084 - 35,465,320 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2435,437,308 - 35,465,203 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605323,674,689 - 23,701,992 (+)NCBIVero_WHO_p1.0
Psma3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248843,324,418 - 3,346,128 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248843,324,390 - 3,346,128 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH127444  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2689,503,492 - 89,503,708 (+)MAPPERmRatBN7.2
Rnor_6.0693,442,743 - 93,442,958NCBIRnor6.0
Rnor_5.06102,898,469 - 102,898,684UniSTSRnor5.0
RGSC_v3.4693,111,885 - 93,112,100UniSTSRGSC3.4
Celera687,985,550 - 87,985,765UniSTS
RH 3.4 Map6639.3UniSTS
Cytogenetic Map6q24UniSTS
RH138090  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2689,485,444 - 89,485,591 (+)MAPPERmRatBN7.2
Rnor_6.0693,424,697 - 93,424,843NCBIRnor6.0
Rnor_5.06102,870,438 - 102,870,584UniSTSRnor5.0
RGSC_v3.4693,093,859 - 93,094,005UniSTSRGSC3.4
Celera687,967,522 - 87,967,668UniSTS
RH 3.4 Map6640.3UniSTS
Cytogenetic Map10q25UniSTS
Cytogenetic Map6q24UniSTS
RH130667  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2689,504,584 - 89,504,785 (+)MAPPERmRatBN7.2
Rnor_6.0693,443,835 - 93,444,035NCBIRnor6.0
Rnor_5.06102,899,561 - 102,899,761UniSTSRnor5.0
RGSC_v3.4693,112,977 - 93,113,177UniSTSRGSC3.4
Celera687,986,642 - 87,986,842UniSTS
RH 3.4 Map6639.5UniSTS
Cytogenetic Map6q24UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
4889848Pur25Proteinuria QTL 25140.003total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)65672856290198260Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)683190345106747639Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:152
Count of miRNA genes:102
Interacting mature miRNAs:124
Transcripts:ENSRNOT00000010753
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000010753   ⟹   ENSRNOP00000010753
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl689,484,684 - 89,501,189 (+)Ensembl
Rnor_6.0 Ensembl693,423,002 - 93,444,240 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000075868
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl693,437,383 - 93,441,873 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000105733   ⟹   ENSRNOP00000084525
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl689,483,740 - 89,504,965 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114457   ⟹   ENSRNOP00000094706
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl689,483,727 - 89,503,086 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000119219   ⟹   ENSRNOP00000096724
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl689,484,684 - 89,501,189 (+)Ensembl
RefSeq Acc Id: NM_017280   ⟹   NP_058976
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2689,483,777 - 89,503,775 (+)NCBI
Rnor_6.0693,423,029 - 93,443,025 (+)NCBI
Rnor_5.06102,868,534 - 102,898,751 (+)NCBI
RGSC_v3.4693,092,191 - 93,112,167 (+)RGD
Celera687,965,854 - 87,985,832 (+)RGD
Sequence:
RefSeq Acc Id: XM_017594059   ⟹   XP_017449548
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2689,483,741 - 89,502,746 (+)NCBI
Rnor_6.0693,424,370 - 93,444,223 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_058976 (Get FASTA)   NCBI Sequence Viewer  
  XP_017449548 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH81817 (Get FASTA)   NCBI Sequence Viewer  
  EDM03560 (Get FASTA)   NCBI Sequence Viewer  
  P18422 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_058976   ⟸   NM_017280
- UniProtKB: P18422 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017449548   ⟸   XM_017594059
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000010753   ⟸   ENSRNOT00000010753
RefSeq Acc Id: ENSRNOP00000084525   ⟸   ENSRNOT00000105733
RefSeq Acc Id: ENSRNOP00000094706   ⟸   ENSRNOT00000114457
RefSeq Acc Id: ENSRNOP00000096724   ⟸   ENSRNOT00000119219

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P18422-F1-model_v2 AlphaFold P18422 1-255 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694647
Promoter ID:EPDNEW_R5170
Type:initiation region
Name:Psma3_1
Description:proteasome subunit alpha 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0693,422,967 - 93,423,027EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61844 AgrOrtholog
BioCyc Gene G2FUF-37187 BioCyc
Ensembl Genes ENSRNOG00000007851 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000084525 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000094706.1 UniProtKB/TrEMBL
  ENSRNOP00000096724.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000105733 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000114457.1 UniProtKB/TrEMBL
  ENSRNOT00000119219.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.20.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7110009 IMAGE-MGC_LOAD
InterPro Ntn_hydrolases_N UniProtKB/Swiss-Prot
  Proteasome_alpha-type UniProtKB/Swiss-Prot
  Proteasome_alpha_3 UniProtKB/Swiss-Prot
  Proteasome_asu_N UniProtKB/Swiss-Prot
  Proteasome_sua/b UniProtKB/Swiss-Prot
KEGG Report rno:29670 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93511 IMAGE-MGC_LOAD
NCBI Gene 29670 ENTREZGENE
PANTHER PTHR11599:SF10 UniProtKB/Swiss-Prot
Pfam Proteasome UniProtKB/Swiss-Prot
  Proteasome_A_N UniProtKB/Swiss-Prot
PhenoGen Psma3 PhenoGen
PROSITE PROTEASOME_ALPHA_1 UniProtKB/Swiss-Prot
  PROTEASOME_ALPHA_2 UniProtKB/Swiss-Prot
SMART Proteasome_A_N UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56235 UniProtKB/Swiss-Prot
TIGR TC216589
UniProt A0A8I6AVH8_RAT UniProtKB/TrEMBL
  A0A8I6B1E1_RAT UniProtKB/TrEMBL
  P18422 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-09-13 Psma3  proteasome 20S subunit alpha 3  Psma3  proteasome subunit alpha 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-08-19 Psma3  proteasome subunit alpha 3  Psma3  proteasome (prosome, macropain) subunit, alpha type 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Psma3  proteasome (prosome, macropain) subunit, alpha type 3      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference