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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2,4-trimethylbenzene | decreases expression | EXP | | 6480464 | pseudocumene results in decreased expression of PSMA3 protein | CTD | PMID:17337753 | 1,2-dimethylhydrazine | multiple interactions | ISO | RGD:62136 | 6480464 | Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in decreased expression of PSMA3 mRNA] | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | RGD:62136 | 6480464 | 1, 2-Dimethylhydrazine results in decreased expression of PSMA3 mRNA | CTD | PMID:22206623 | 1,3-dinitrobenzene | increases expression | EXP | | 6480464 | 3-dinitrobenzene results in increased expression of PSMA3 mRNA | CTD | PMID:24140754 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | RGD:62136 | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:19954255 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | RGD:62136 | 6480464 | 4, 4'-diaminodiphenylmethane results in decreased expression of PSMA3 mRNA | CTD | PMID:18648102 | acrolein | multiple interactions | ISO | RGD:732188 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PSMA3 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PSMA3 mRNA | CTD | PMID:32699268 | aflatoxin B1 | decreases methylation | ISO | RGD:732188 | 6480464 | Aflatoxin B1 results in decreased methylation of PSMA3 gene | CTD | PMID:27153756 | alpha-pinene | multiple interactions | ISO | RGD:732188 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PSMA3 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PSMA3 mRNA | CTD | PMID:32699268 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of PSMA3 mRNA | CTD | PMID:16483693 | ampicillin | multiple interactions | EXP | | 6480464 | [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of PSMA3 protein | CTD | PMID:30545405 | aristolochic acid | decreases expression | ISO | RGD:732188 | 6480464 | aristolochic acid I results in decreased expression of PSMA3 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | RGD:732188 | 6480464 | Arsenic affects the methylation of PSMA3 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | RGD:732188 | 6480464 | Arsenic affects the methylation of PSMA3 gene | CTD | PMID:25304211 | arsenite(3-) | decreases expression | ISO | RGD:62136 | 6480464 | arsenite results in decreased expression of PSMA3 mRNA | CTD | PMID:33053406 | arsenite(3-) | multiple interactions | ISO | RGD:732188 | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to PSMA3 mRNA] | CTD | PMID:32406909 | bis(2-chloroethyl) sulfide | affects expression | EXP | | 6480464 | Mustard Gas affects the expression of PSMA3 mRNA | CTD | PMID:15651846 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PSMA3 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | RGD:732188 | 6480464 | bisphenol A results in decreased expression of PSMA3 mRNA | CTD | PMID:29275510 | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of PSMA3 mRNA | CTD | PMID:12628495 | bufalin | decreases expression | ISO | RGD:732188 | 6480464 | bufalin results in decreased expression of PSMA3 protein | CTD | PMID:23091618 | clofibrate | multiple interactions | ISO | RGD:62136 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of PSMA3 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of PSMA3 mRNA] | CTD | PMID:17585979 | clofibrate | increases expression | ISO | RGD:62136 | 6480464 | Clofibrate results in increased expression of PSMA3 mRNA | CTD | PMID:17585979 | cyclosporin A | increases expression | ISO | RGD:732188 | 6480464 | Cyclosporine results in increased expression of PSMA3 mRNA | CTD | PMID:20106945, PMID:25562108 | dibenzo[a,l]pyrene | decreases expression | ISO | RGD:62136 | 6480464 | dibenzo(a, l)pyrene results in decreased expression of PSMA3 mRNA | CTD | PMID:25908611 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of PSMA3 mRNA | CTD | PMID:21266533 | dicrotophos | decreases expression | ISO | RGD:732188 | 6480464 | dicrotophos results in decreased expression of PSMA3 mRNA | CTD | PMID:28302478 | dimethylarsinous acid | decreases expression | ISO | RGD:732188 | 6480464 | dimethylarsinous acid results in decreased expression of PSMA3 mRNA | CTD | PMID:16507463 | doxorubicin | increases metabolic processing | ISO | RGD:732188 | 6480464 | Doxorubicin results in increased metabolism of PSMA3 protein | CTD | PMID:17346995 | ethanol | increases expression | ISO | RGD:62136 | 6480464 | Ethanol results in increased expression of PSMA3 mRNA | CTD | PMID:30319688 | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of PSMA3 mRNA | CTD | PMID:24136188 | fluoxetine | affects expression | EXP | | 6480464 | Fluoxetine affects the expression of PSMA3 mRNA | CTD | PMID:21852994 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of PSMA3 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | RGD:62136 | 6480464 | Folic Acid inhibits the reaction [1, 2-Dimethylhydrazine results in decreased expression of PSMA3 mRNA] | CTD | PMID:22206623 | genistein | multiple interactions | EXP | | 6480464 | [Genistein co-treated with Methoxychlor] results in increased expression of PSMA3 mRNA | CTD | PMID:21782745 | genistein | increases expression | ISO | RGD:62136 | 6480464 | Genistein results in increased expression of PSMA3 mRNA | CTD | PMID:32186404 | gentamycin | multiple interactions | EXP | | 6480464 | [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of PSMA3 protein | CTD | PMID:30545405 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of PSMA3 mRNA | CTD | PMID:22061828 | hydrogen peroxide | affects expression | ISO | RGD:732188 | 6480464 | Hydrogen Peroxide affects the expression of PSMA3 mRNA | CTD | PMID:20044591 | isotretinoin | decreases expression | ISO | RGD:732188 | 6480464 | Isotretinoin results in decreased expression of PSMA3 mRNA | CTD | PMID:20436886 | ivermectin | decreases expression | ISO | RGD:732188 | 6480464 | Ivermectin results in decreased expression of PSMA3 protein | CTD | PMID:32959892 | lovastatin | decreases expression | ISO | RGD:62136 | 6480464 | Lovastatin results in decreased expression of PSMA3 mRNA | CTD | PMID:20493250 | methidathion | decreases expression | ISO | RGD:62136 | 6480464 | methidathion results in decreased expression of PSMA3 mRNA | CTD | PMID:34813904 | methoxychlor | multiple interactions | EXP | | 6480464 | [Genistein co-treated with Methoxychlor] results in increased expression of PSMA3 mRNA | CTD | PMID:21782745 | methoxychlor | increases expression | EXP | | 6480464 | Methoxychlor results in increased expression of PSMA3 mRNA | CTD | PMID:21782745 | metronidazole | multiple interactions | EXP | | 6480464 | [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of PSMA3 protein | CTD | PMID:30545405 | monocrotaline | increases expression | EXP | | 6480464 | Monocrotaline results in increased expression of PSMA3 mRNA | CTD | PMID:18801959 | monocrotaline | multiple interactions | EXP | | 6480464 | Pentoxifylline inhibits the reaction [Monocrotaline results in increased expression of PSMA3 mRNA] | CTD | PMID:18801959 | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | increases expression | ISO | RGD:62136 | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMA3 mRNA | CTD | PMID:15525353 | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | increases expression | ISO | RGD:732188 | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMA3 mRNA | CTD | PMID:31806706 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of PSMA3 mRNA | CTD | PMID:24136188 | neomycin | multiple interactions | EXP | | 6480464 | [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of PSMA3 protein | CTD | PMID:30545405 | nickel atom | increases expression | ISO | RGD:732188 | 6480464 | Nickel results in increased expression of PSMA3 mRNA | CTD | PMID:25583101 | nickel subsulfide | increases expression | ISO | RGD:732188 | 6480464 | nickel subsulfide results in increased expression of PSMA3 mRNA | CTD | PMID:12760830 | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of PSMA3 mRNA | CTD | PMID:24136188 | ozone | multiple interactions | ISO | RGD:732188 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PSMA3 mRNA more ... | CTD | PMID:32699268 | p-menthan-3-ol | increases expression | ISO | RGD:732188 | 6480464 | Menthol results in increased expression of PSMA3 protein | CTD | PMID:26760959 | paracetamol | multiple interactions | ISO | RGD:62136 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of PSMA3 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of PSMA3 mRNA] | CTD | PMID:17585979 | paracetamol | decreases expression | ISO | RGD:732188 | 6480464 | Acetaminophen results in decreased expression of PSMA3 mRNA | CTD | PMID:22230336 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of PSMA3 protein | CTD | PMID:16538041 | Pentoxifylline | multiple interactions | EXP | | 6480464 | Pentoxifylline inhibits the reaction [Monocrotaline results in increased expression of PSMA3 mRNA] | CTD | PMID:18801959 | perfluorooctane-1-sulfonic acid | affects expression | ISO | RGD:62136 | 6480464 | perfluorooctane sulfonic acid affects the expression of PSMA3 mRNA | CTD | PMID:19429403 | perfluorooctanoic acid | affects expression | ISO | RGD:62136 | 6480464 | perfluorooctanoic acid affects the expression of PSMA3 mRNA | CTD | PMID:19429403 | phenethyl isothiocyanate | affects binding | ISO | RGD:732188 | 6480464 | PSMA3 protein binds to phenethyl isothiocyanate | CTD | PMID:21838287 | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of PSMA3 mRNA | CTD | PMID:19162173 | picrotoxin | decreases expression | EXP | | 6480464 | Picrotoxin results in decreased expression of PSMA3 mRNA | CTD | PMID:15170462 | pirinixic acid | increases expression | ISO | RGD:62136 | 6480464 | pirinixic acid results in increased expression of PSMA3 mRNA | CTD | PMID:15375163, PMID:23811191 | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of PSMA3 mRNA | CTD | PMID:19162173 | quinoline | decreases expression | ISO | RGD:732188 | 6480464 | quinoline analog results in decreased expression of PSMA3 protein | CTD | PMID:18645022 | resveratrol | multiple interactions | ISO | RGD:732188 | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of PSMA3 mRNA | CTD | PMID:23557933 | rotenone | increases oxidation | EXP | | 6480464 | Rotenone results in increased oxidation of PSMA3 protein | CTD | PMID:30951809 | rotenone | multiple interactions | ISO | RGD:732188 | 6480464 | Rotenone promotes the reaction [NFE2L1 protein binds to PSMA3 promoter] | CTD | PMID:27345029 | sarin | decreases expression | ISO | RGD:732188 | 6480464 | Sarin results in decreased expression of PSMA3 mRNA | CTD | PMID:19522546 | sarin | increases expression | ISO | RGD:732188 | 6480464 | Sarin results in increased expression of PSMA3 mRNA | CTD | PMID:19522546 | sunitinib | decreases expression | ISO | RGD:732188 | 6480464 | Sunitinib results in decreased expression of PSMA3 mRNA | CTD | PMID:31533062 | Tributyltin oxide | increases phosphorylation | ISO | RGD:62136 | 6480464 | bis(tri-n-butyltin)oxide results in increased phosphorylation of PSMA3 protein | CTD | PMID:22174045 | tungsten | increases expression | ISO | RGD:62136 | 6480464 | Tungsten results in increased expression of PSMA3 mRNA | CTD | PMID:30912803 | valdecoxib | increases expression | EXP | | 6480464 | valdecoxib results in increased expression of PSMA3 mRNA | CTD | PMID:24136188 | vancomycin | multiple interactions | EXP | | 6480464 | [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of PSMA3 protein | CTD | PMID:30545405 | vorinostat | increases expression | ISO | RGD:732188 | 6480464 | vorinostat results in increased expression of PSMA3 mRNA | CTD | PMID:27188386 | warfarin | decreases expression | ISO | RGD:62136 | 6480464 | Warfarin results in decreased expression of PSMA3 mRNA | CTD | PMID:20493250 | |