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Gene: Bdkrb1 (bradykinin receptor B1) Rattus norvegicus
Symbol: Bdkrb1
Name: bradykinin receptor B1
RGD ID: 620401
Description: Exhibits bradykinin receptor activity and peptide binding activity. Involved in several processes, including positive regulation of release of sequestered calcium ion into cytosol; protein kinase C-activating G protein-coupled receptor signaling pathway; and response to lipopolysaccharide. Localizes to neuron projection and plasma membrane. Used to study diabetic angiopathy; epilepsy; hypertension; neuropathy (multiple); and pleurisy. Biomarker of hypertension and myocardial infarction. Human ortholog(s) of this gene implicated in end stage renal disease; hypertension; and pulmonary fibrosis. Orthologous to human BDKRB1 (bradykinin receptor B1); PARTICIPATES IN G protein mediated signaling pathway via Galphai family; G protein mediated signaling pathway via Galphaq family; kallikrein-kinin cascade pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 3',5'-cyclic GMP.
Type: protein-coding
Also known as: B1 bradykinin receptor; b1bkr; B1R; Bdkrb; BK-1 receptor; BKR; bradykinin B1 receptor; bradykinin receptor, beta 1; KB1; kinin B1; kinin B1 receptor
Homo sapiens (human) : BDKRB1 (bradykinin receptor B1)  HGNC  Alliance
Mus musculus (house mouse) : Bdkrb1 (bradykinin receptor, beta 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bdkrb1 (bradykinin receptor B1)
Pan paniscus (bonobo/pygmy chimpanzee) : BDKRB1 (bradykinin receptor B1)
Canis lupus familiaris (dog) : BDKRB1 (bradykinin receptor B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bdkrb1 (bradykinin receptor B1)
Sus scrofa (pig) : BDKRB1 (bradykinin receptor B1)
Chlorocebus sabaeus (African green monkey) : BDKRB1 (bradykinin receptor B1)
Heterocephalus glaber (naked mole-rat) : Bdkrb1 (bradykinin receptor B1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.06129,437,423 - 129,441,553 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6129,438,158 - 129,440,574 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06138,631,450 - 138,633,866 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46129,760,129 - 129,762,545 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16129,763,875 - 129,766,292 (+)NCBI
Celera6122,077,962 - 122,080,378 (+)NCBICelera
Cytogenetic Map6q32NCBI
RH 3.4 Map6821.1RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Bdkrb1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620401
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.