Ston2 (stonin 2) - Rat Genome Database

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Gene: Ston2 (stonin 2) Rattus norvegicus
Analyze
Symbol: Ston2
Name: stonin 2
RGD ID: 1311502
Description: Predicted to enable clathrin adaptor activity. Involved in synaptic vesicle endocytosis. Is active in presynapse. Orthologous to human STON2 (stonin 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: homolog of stoned B; homolog of stoned B (Drosophila); LOC314349; RGD1311502; similar to stonin 2; stonin-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86116,291,898 - 116,441,391 (-)NCBIGRCr8
mRatBN7.26110,567,485 - 110,676,376 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6110,567,485 - 110,676,376 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6110,706,947 - 110,808,561 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06111,005,598 - 111,107,207 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06110,379,693 - 110,481,984 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06115,398,586 - 115,547,552 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6115,399,326 - 115,513,354 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06124,652,696 - 124,799,442 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46115,258,140 - 115,369,129 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16115,263,718 - 115,372,603 (-)NCBI
Celera6108,317,847 - 108,421,105 (-)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
alpha-Zearalanol  (EXP)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
CGP 52608  (ISO)
chloroprene  (EXP)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
corosolic acid  (ISO)
coumestrol  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dorsomorphin  (ISO)
Enterolactone  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
maneb  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenylmercury acetate  (ISO)
PhIP  (ISO)
potassium dichromate  (ISO)
pyridaben  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sunitinib  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
torcetrapib  (ISO)
trichostatin A  (ISO)
trifluoperazine  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Stonin 2 is an AP-2-dependent endocytic sorting adaptor for synaptotagmin internalization and recycling. Diril MK, etal., Dev Cell. 2006 Feb;10(2):233-44. doi: 10.1016/j.devcel.2005.12.011.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. CSN complex controls the stability of selected synaptic proteins via a torsinA-dependent process. Granata A, etal., EMBO J. 2011 Jan 5;30(1):181-93. doi: 10.1038/emboj.2010.285. Epub 2010 Nov 19.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Stonin 2 is a major adaptor protein for clathrin-mediated synaptic vesicle retrieval. Willox AK and Royle SJ, Curr Biol. 2012 Aug 7;22(15):1435-9. doi: 10.1016/j.cub.2012.05.048. Epub 2012 Jun 21.
Additional References at PubMed
PMID:14726597   PMID:18200045   PMID:24029230   PMID:29476059   PMID:31904090  


Genomics

Comparative Map Data
Ston2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86116,291,898 - 116,441,391 (-)NCBIGRCr8
mRatBN7.26110,567,485 - 110,676,376 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6110,567,485 - 110,676,376 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6110,706,947 - 110,808,561 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06111,005,598 - 111,107,207 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06110,379,693 - 110,481,984 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06115,398,586 - 115,547,552 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6115,399,326 - 115,513,354 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06124,652,696 - 124,799,442 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46115,258,140 - 115,369,129 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16115,263,718 - 115,372,603 (-)NCBI
Celera6108,317,847 - 108,421,105 (-)NCBICelera
Cytogenetic Map6q31NCBI
STON2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381481,260,652 - 81,436,465 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1481,260,652 - 81,436,465 (-)EnsemblGRCh38hg38GRCh38
GRCh371481,726,996 - 81,902,809 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361480,806,662 - 80,934,680 (-)NCBINCBI36Build 36hg18NCBI36
Celera1461,776,811 - 61,904,826 (-)NCBICelera
Cytogenetic Map14q31.1NCBI
HuRef1461,894,797 - 62,062,854 (-)NCBIHuRef
CHM1_11481,667,203 - 81,831,467 (-)NCBICHM1_1
T2T-CHM13v2.01475,472,819 - 75,651,273 (-)NCBIT2T-CHM13v2.0
Ston2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391291,599,686 - 91,753,237 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1291,641,586 - 91,652,887 (-)EnsemblGRCm39 Ensembl
GRCm39 Ensembl1291,599,783 - 91,755,161 (-)EnsemblGRCm39 Ensembl
GRCm381291,633,009 - 91,786,436 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1291,633,009 - 91,788,387 (-)EnsemblGRCm38mm10GRCm38
MGSCv371292,871,449 - 93,024,876 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361292,044,099 - 92,191,993 (-)NCBIMGSCv36mm8
Celera1292,934,475 - 93,088,109 (-)NCBICelera
Cytogenetic Map12D3NCBI
cM Map1245.02NCBI
Ston2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554384,877,351 - 4,979,714 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554384,877,351 - 4,977,569 (-)NCBIChiLan1.0ChiLan1.0
STON2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21582,370,886 - 82,547,028 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11481,587,489 - 81,763,494 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01461,837,145 - 62,013,251 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11481,037,191 - 81,210,807 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1481,037,200 - 81,210,807 (-)Ensemblpanpan1.1panPan2
STON2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1853,591,194 - 53,725,710 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl853,597,780 - 53,725,688 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha853,149,203 - 53,293,840 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0853,820,758 - 53,965,726 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl853,827,298 - 53,965,632 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1853,502,266 - 53,646,700 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0853,506,356 - 53,650,604 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0853,898,648 - 54,043,523 (-)NCBIUU_Cfam_GSD_1.0
Ston2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864022,252,263 - 22,385,986 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364889,682,823 - 9,816,703 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364889,689,595 - 9,816,672 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STON2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7104,039,493 - 104,189,701 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17104,034,913 - 104,189,735 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27110,031,651 - 110,150,975 (-)NCBISscrofa10.2Sscrofa10.2susScr3
STON2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12458,588,826 - 58,733,645 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605346,312,620 - 46,489,501 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ston2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473420,657,303 - 20,763,692 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473420,618,244 - 20,770,266 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ston2
753 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:73
Count of miRNA genes:64
Interacting mature miRNAs:69
Transcripts:ENSRNOT00000005881
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6104085867128713626Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1300076Glom8Glomerulus QTL 879e-09kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat

Markers in Region
D6Got158  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26110,645,599 - 110,645,706 (+)MAPPERmRatBN7.2
Rnor_6.06115,482,959 - 115,483,065NCBIRnor6.0
Rnor_5.06124,734,624 - 124,734,730UniSTSRnor5.0
RGSC_v3.46115,336,772 - 115,336,879RGDRGSC3.4
RGSC_v3.46115,336,773 - 115,336,879UniSTSRGSC3.4
RGSC_v3.16115,340,304 - 115,340,410RGD
Celera6108,394,275 - 108,394,365UniSTS
RH 3.4 Map6761.0UniSTS
RH 3.4 Map6761.0RGD
RH 2.0 Map6963.5RGD
Cytogenetic Map6q31UniSTS
BF399472  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26110,670,054 - 110,670,229 (+)MAPPERmRatBN7.2
Rnor_6.06115,507,447 - 115,507,621NCBIRnor6.0
Rnor_5.06124,759,291 - 124,759,465UniSTSRnor5.0
RGSC_v3.46115,362,806 - 115,362,980UniSTSRGSC3.4
Celera6108,414,553 - 108,414,727UniSTS
RH 3.4 Map6762.0UniSTS
Cytogenetic Map6q31UniSTS
RH138201  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26110,617,849 - 110,617,994 (+)MAPPERmRatBN7.2
Rnor_6.06115,455,209 - 115,455,353NCBIRnor6.0
Rnor_5.06124,706,874 - 124,707,018UniSTSRnor5.0
RGSC_v3.46115,309,024 - 115,309,168UniSTSRGSC3.4
Celera6108,366,777 - 108,366,921UniSTS
RH 3.4 Map6761.1UniSTS
Cytogenetic Map6q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000005881   ⟹   ENSRNOP00000005881
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6110,567,485 - 110,676,376 (-)Ensembl
Rnor_6.0 Ensembl6115,399,326 - 115,513,354 (-)Ensembl
RefSeq Acc Id: NM_001135874   ⟹   NP_001129346
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86116,298,198 - 116,407,092 (-)NCBI
mRatBN7.26110,567,485 - 110,676,376 (-)NCBI
Rnor_6.06115,399,326 - 115,513,354 (-)NCBI
Rnor_5.06124,652,696 - 124,799,442 (-)NCBI
RGSC_v3.46115,258,140 - 115,369,129 (-)RGD
Celera6108,317,847 - 108,421,105 (-)RGD
Sequence:
RefSeq Acc Id: XM_063261952   ⟹   XP_063118022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86116,291,898 - 116,414,034 (-)NCBI
RefSeq Acc Id: XM_063261953   ⟹   XP_063118023
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86116,291,898 - 116,441,391 (-)NCBI
RefSeq Acc Id: XM_063261954   ⟹   XP_063118024
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86116,291,898 - 116,342,008 (-)NCBI
RefSeq Acc Id: NP_001129346   ⟸   NM_001135874
- UniProtKB: D4AB66 (UniProtKB/Swiss-Prot),   A6JEC9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000005881   ⟸   ENSRNOT00000005881
RefSeq Acc Id: XP_063118023   ⟸   XM_063261953
- Peptide Label: isoform X1
- UniProtKB: D4AB66 (UniProtKB/Swiss-Prot),   A6JEC9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118022   ⟸   XM_063261952
- Peptide Label: isoform X1
- UniProtKB: D4AB66 (UniProtKB/Swiss-Prot),   A6JEC9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118024   ⟸   XM_063261954
- Peptide Label: isoform X2
Protein Domains
MHD   SHD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AB66-F1-model_v2 AlphaFold D4AB66 1-895 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311502 AgrOrtholog
BioCyc Gene G2FUF-36650 BioCyc
Ensembl Genes ENSRNOG00000004458 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00065027866 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000005881.5 UniProtKB/Swiss-Prot
  ENSRNOT00065048052 UniProtKB/Swiss-Prot
Gene3D-CATH Mu homology domain, subdomain B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Adaptor_comp_med_subunit UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AP2_Mu_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SHD_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STON2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Stonin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Stonin2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:314349 UniProtKB/Swiss-Prot
NCBI Gene 314349 ENTREZGENE
PANTHER AP COMPLEX SUBUNIT MU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10529:SF345 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Adap_comp_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Stonin2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ston2 PhenoGen
PIRSF Stonin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE MHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004458 RatGTEx
  ENSRNOG00065027866 RatGTEx
Superfamily-SCOP Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A6JEC9 ENTREZGENE, UniProtKB/TrEMBL
  D4AB66 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Ston2  stonin 2   Ston2_predicted  stonin 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Ston2_predicted  stonin 2 (predicted)  RGD1311502_predicted  similar to stonin 2; homolog of stoned B (Drosophila) (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1311502_predicted  similar to stonin 2; homolog of stoned B (Drosophila) (predicted)  LOC314349_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC314349_predicted  similar to stonin 2; homolog of stoned B (Drosophila) (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL