Fancm (FA complementation group M) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Fancm (FA complementation group M) Rattus norvegicus
Analyze
Symbol: Fancm
Name: FA complementation group M
RGD ID: 1307897
Description: Predicted to have chromatin binding activity. Predicted to be involved in positive regulation of protein monoubiquitination; replication fork processing; and resolution of meiotic recombination intermediates. Predicted to localize to FANCM-MHF complex; Fanconi anaemia nuclear complex; and nucleoplasm. Human ortholog(s) of this gene implicated in primary ovarian insufficiency and spermatogenic failure 28. Orthologous to human FANCM (FA complementation group M); INTERACTS WITH bisphenol A; (-)-epigallocatechin 3-gallate (ortholog); 1,2-dichloroethane (ortholog).
Type: gene
RefSeq Status: MODEL
Also known as: Fanconi anemia, complementation group M; LOC314172; RGD1307897; similar to RIKEN cDNA C730036B14 gene
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2683,126,903 - 83,180,455 (+)NCBI
Rnor_6.0 Ensembl686,823,684 - 86,876,633 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0686,823,195 - 86,877,067 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0696,312,237 - 96,365,616 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4686,424,156 - 86,476,902 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1686,462,951 - 86,480,559 (+)NCBI
Celera681,694,524 - 81,748,389 (+)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:12477932   PMID:20347428   PMID:20347429   PMID:29231814  


Genomics

Comparative Map Data
Fancm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2683,126,903 - 83,180,455 (+)NCBI
Rnor_6.0 Ensembl686,823,684 - 86,876,633 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0686,823,195 - 86,877,067 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0696,312,237 - 96,365,616 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4686,424,156 - 86,476,902 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1686,462,951 - 86,480,559 (+)NCBI
Celera681,694,524 - 81,748,389 (+)NCBICelera
Cytogenetic Map6q24NCBI
FANCM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1445,135,930 - 45,200,890 (+)EnsemblGRCh38hg38GRCh38
GRCh381445,135,930 - 45,200,890 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371445,605,133 - 45,670,093 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361444,674,886 - 44,739,840 (+)NCBINCBI36hg18NCBI36
Celera1425,466,389 - 25,531,345 (+)NCBI
Cytogenetic Map14q21.2NCBI
HuRef1425,716,007 - 25,780,814 (+)NCBIHuRef
CHM1_11445,543,290 - 45,608,236 (+)NCBICHM1_1
Fancm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391265,120,884 - 65,178,616 (+)NCBIGRCm39mm39
GRCm39 Ensembl1265,122,377 - 65,178,832 (+)Ensembl
GRCm381265,074,110 - 65,131,842 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1265,075,603 - 65,132,058 (+)EnsemblGRCm38mm10GRCm38
MGSCv371266,176,593 - 66,233,045 (+)NCBIGRCm37mm9NCBIm37
MGSCv361265,994,211 - 66,050,663 (+)NCBImm8
Celera1266,205,293 - 66,261,759 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1227.21NCBI
Fancm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540916,751,658 - 16,809,352 (-)NCBIChiLan1.0ChiLan1.0
FANCM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11444,080,146 - 44,143,958 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1444,080,146 - 44,143,958 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01425,752,295 - 25,817,001 (+)NCBIMhudiblu_PPA_v0panPan3
FANCM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl822,562,147 - 22,623,994 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1822,561,862 - 22,625,077 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Fancm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365834,085,802 - 4,145,621 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FANCM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1175,334,047 - 175,445,650 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11175,333,965 - 175,402,065 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21195,220,132 - 195,287,229 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FANCM
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12422,255,750 - 22,327,191 (+)NCBI
ChlSab1.1 Ensembl2422,256,236 - 22,329,609 (+)Ensembl
Fancm
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473123,342,313 - 23,391,877 (-)NCBI

Position Markers
D6Got109  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0686,858,364 - 86,858,626NCBIRnor6.0
Rnor_5.0696,347,343 - 96,347,605UniSTSRnor5.0
RGSC_v3.4686,458,835 - 86,459,098RGDRGSC3.4
RGSC_v3.4686,458,836 - 86,459,098UniSTSRGSC3.4
RGSC_v3.1686,462,292 - 86,462,554RGD
Celera681,729,686 - 81,729,948UniSTS
RH 3.4 Map6550.8RGD
RH 3.4 Map6550.8UniSTS
RH 2.0 Map6796.1RGD
Cytogenetic Map6q24UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)62537030111715717Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)67009971115379601Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)648432758108268790Rat
4889848Pur25Proteinuria QTL 25140.003total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)65980306594001333Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)660606431108154445Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)660606431108154445Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)662263348107263348Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)666129520111129520Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)668781170147991367Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)668781170147991367Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)671206251116206251Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)675449871120449871Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)675623277120276465Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)675623277120623277Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)675623277136143011Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)675623277136426962Rat
1581550Pur8Proteinuria QTL 8total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)675623393136142742Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)675623393136142742Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)676902247114203334Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)684763275108464097Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)684763275108464097Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)686422697115379601Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 6 32 16 18 16 61 20 32 5
Low 3 37 25 25 1 25 8 10 13 15 9 6 8
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000006574   ⟹   ENSRNOP00000006574
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl686,823,688 - 86,852,282 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000059244   ⟹   ENSRNOP00000056011
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl686,852,323 - 86,876,633 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000086081   ⟹   ENSRNOP00000074177
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl686,823,684 - 86,876,599 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000086894   ⟹   ENSRNOP00000073969
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl686,872,903 - 86,876,633 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000087186
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl686,871,430 - 86,873,062 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000088683
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl686,866,374 - 86,871,703 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093492   ⟹   ENSRNOP00000076245
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl686,862,790 - 86,873,711 (+)Ensembl
RefSeq Acc Id: XR_001838440
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0686,823,195 - 86,876,637 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001844057
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera681,694,524 - 81,747,959 (+)NCBI
Sequence:
RefSeq Acc Id: XR_005505981
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2683,127,167 - 83,180,025 (+)NCBI
RefSeq Acc Id: XR_005505982
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2683,127,167 - 83,179,037 (+)NCBI
RefSeq Acc Id: XR_005505983
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2683,127,167 - 83,179,778 (+)NCBI
RefSeq Acc Id: XR_347272
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera681,694,525 - 81,747,697 (+)NCBI
Sequence:
RefSeq Acc Id: XR_347273
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera681,694,525 - 81,744,407 (+)NCBI
Sequence:
RefSeq Acc Id: XR_347274
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera681,694,525 - 81,741,281 (+)NCBI
Sequence:
RefSeq Acc Id: XR_347275
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera681,694,525 - 81,747,661 (+)NCBI
Sequence:
RefSeq Acc Id: XR_347276
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera681,694,525 - 81,743,115 (+)NCBI
Sequence:
RefSeq Acc Id: XR_354853
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2683,127,167 - 83,179,819 (+)NCBI
Rnor_6.0686,823,196 - 86,876,375 (+)NCBI
Sequence:
RefSeq Acc Id: XR_354854
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0686,823,196 - 86,873,085 (+)NCBI
Sequence:
RefSeq Acc Id: XR_354855
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2683,127,167 - 83,174,670 (+)NCBI
Rnor_6.0686,823,196 - 86,869,959 (+)NCBI
Sequence:
RefSeq Acc Id: XR_354856
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2683,127,167 - 83,179,787 (+)NCBI
Rnor_6.0686,823,196 - 86,876,339 (+)NCBI
Sequence:
RefSeq Acc Id: XR_354857
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2683,127,167 - 83,175,181 (+)NCBI
Rnor_6.0686,823,196 - 86,871,793 (+)NCBI
Sequence:
RefSeq Acc Id: XR_593052
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2683,126,903 - 83,180,455 (+)NCBI
Rnor_6.0686,823,195 - 86,877,067 (+)NCBI
Sequence:
RefSeq Acc Id: XR_593053
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0686,823,195 - 86,874,658 (+)NCBI
Sequence:
RefSeq Acc Id: XR_601463
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera681,694,524 - 81,748,389 (+)NCBI
Sequence:
RefSeq Acc Id: XR_601464
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera681,694,524 - 81,745,980 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_234239 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH91339 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: ENSRNOP00000006574   ⟸   ENSRNOT00000006574
RefSeq Acc Id: ENSRNOP00000076245   ⟸   ENSRNOT00000093492
RefSeq Acc Id: ENSRNOP00000073969   ⟸   ENSRNOT00000086894
RefSeq Acc Id: ENSRNOP00000056011   ⟸   ENSRNOT00000059244
RefSeq Acc Id: ENSRNOP00000074177   ⟸   ENSRNOT00000086081
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694628
Promoter ID:EPDNEW_R5151
Type:multiple initiation site
Name:Fancm_1
Description:Fanconi anemia, complementation group M
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0686,823,669 - 86,823,729EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307897 AgrOrtholog
Ensembl Genes ENSRNOG00000056721 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000006574 UniProtKB/TrEMBL
  ENSRNOP00000056011 UniProtKB/TrEMBL
  ENSRNOP00000073969 UniProtKB/TrEMBL
  ENSRNOP00000074177 UniProtKB/TrEMBL
  ENSRNOP00000076245 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006574 UniProtKB/TrEMBL
  ENSRNOT00000059244 UniProtKB/TrEMBL
  ENSRNOT00000086081 UniProtKB/TrEMBL
  ENSRNOT00000086894 UniProtKB/TrEMBL
  ENSRNOT00000093492 UniProtKB/TrEMBL
InterPro ERCC4_domain UniProtKB/TrEMBL
  FANCM-MHF-bd UniProtKB/TrEMBL
  FANCM/Mph1-like UniProtKB/TrEMBL
  Helicase/UvrB_N UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Restrict_endonuc_II-like_core UniProtKB/TrEMBL
  RuvA_2-like UniProtKB/TrEMBL
NCBI Gene Fancm ENTREZGENE
PANTHER PTHR14025:SF20 UniProtKB/TrEMBL
Pfam ERCC4 UniProtKB/TrEMBL
  FANCM-MHF_bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  ResIII UniProtKB/TrEMBL
PhenoGen Fancm PhenoGen
PROSITE HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  ERCC4 UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP Restrict_endonuc_II-like_core UniProtKB/TrEMBL
  SSF47781 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A0G2K6W7_RAT UniProtKB/TrEMBL
  A0A0G2K7F0_RAT UniProtKB/TrEMBL
  A0A1W2Q6G5_RAT UniProtKB/TrEMBL
  D3ZJ52_RAT UniProtKB/TrEMBL
  F7FA21_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-25 Fancm  FA complementation group M  Fancm  Fanconi anemia, complementation group M  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-07-29 Fancm  Fanconi anemia, complementation group M  RGD1307897  similar to RIKEN cDNA C730036B14 gene  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1307897  similar to RIKEN cDNA C730036B14 gene  RGD1307897_predicted  similar to RIKEN cDNA C730036B14 gene (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1307897_predicted  similar to RIKEN cDNA C730036B14 gene (predicted)  LOC314172_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC314172_predicted  similar to RIKEN cDNA C730036B14 gene (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL