Dcaf5 (DDB1 and CUL4 associated factor 5) - Rat Genome Database

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Gene: Dcaf5 (DDB1 and CUL4 associated factor 5) Rattus norvegicus
Analyze
Symbol: Dcaf5
Name: DDB1 and CUL4 associated factor 5
RGD ID: 1306535
Description: Predicted to be involved in negative regulation of fatty acid biosynthetic process. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to human DCAF5 (DDB1 and CUL4 associated factor 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: breakpoint cluster region protein, uterine leiomyoma, 2; DDB1- and CUL4-associated factor 5; DDB1- and CUL4-associated factor 5-like; LOC102553533; LOC314273; WD repeat domain 22; Wdr22
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2699,171,506 - 99,260,183 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl699,171,506 - 99,260,110 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx699,594,245 - 99,682,572 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0699,893,357 - 99,981,686 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0699,273,351 - 99,362,039 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06103,516,586 - 103,605,288 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6103,516,586 - 103,605,256 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06111,691,590 - 111,780,260 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46103,364,401 - 103,451,568 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16103,367,001 - 103,460,615 (-)NCBI
Celera697,527,557 - 97,615,982 (-)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:16949367   PMID:18614015  


Genomics

Comparative Map Data
Dcaf5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2699,171,506 - 99,260,183 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl699,171,506 - 99,260,110 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx699,594,245 - 99,682,572 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0699,893,357 - 99,981,686 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0699,273,351 - 99,362,039 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06103,516,586 - 103,605,288 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6103,516,586 - 103,605,256 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06111,691,590 - 111,780,260 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46103,364,401 - 103,451,568 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16103,367,001 - 103,460,615 (-)NCBI
Celera697,527,557 - 97,615,982 (-)NCBICelera
Cytogenetic Map6q24NCBI
DCAF5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381469,050,881 - 69,153,197 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1469,050,881 - 69,153,150 (-)EnsemblGRCh38hg38GRCh38
GRCh371469,517,598 - 69,619,914 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361468,587,395 - 68,689,502 (-)NCBINCBI36Build 36hg18NCBI36
Build 341468,587,394 - 68,689,502NCBI
Celera1449,581,760 - 49,684,074 (-)NCBICelera
Cytogenetic Map14q24.1NCBI
HuRef1449,688,338 - 49,790,602 (-)NCBIHuRef
CHM1_11469,455,892 - 69,558,157 (-)NCBICHM1_1
T2T-CHM13v2.01463,263,958 - 63,366,302 (-)NCBIT2T-CHM13v2.0
Dcaf5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391280,382,622 - 80,483,375 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1280,382,622 - 80,483,375 (-)EnsemblGRCm39 Ensembl
GRCm381280,335,848 - 80,436,601 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1280,335,848 - 80,436,601 (-)EnsemblGRCm38mm10GRCm38
MGSCv371281,436,834 - 81,537,588 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361281,255,531 - 81,355,387 (-)NCBIMGSCv36mm8
Celera1281,801,313 - 81,901,674 (-)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1236.61NCBI
Dcaf5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554661,216,300 - 1,322,704 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554661,216,966 - 1,322,704 (+)NCBIChiLan1.0ChiLan1.0
DCAF5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11469,387,772 - 69,490,173 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01449,640,440 - 49,743,118 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11468,514,979 - 68,616,974 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1468,514,979 - 68,616,968 (-)Ensemblpanpan1.1panPan2
DCAF5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1842,883,095 - 42,984,686 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl842,882,774 - 42,985,188 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha842,572,496 - 42,673,981 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0843,110,372 - 43,213,983 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl843,112,930 - 43,213,968 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1842,724,750 - 42,828,308 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0842,802,145 - 42,903,187 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0843,158,765 - 43,262,337 (-)NCBIUU_Cfam_GSD_1.0
Dcaf5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864061,806,363 - 61,902,051 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649512,288,748 - 12,356,919 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649512,289,648 - 12,357,640 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCAF5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl792,715,384 - 92,812,979 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1792,717,544 - 92,813,297 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2798,963,907 - 99,037,731 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DCAF5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12446,273,732 - 46,384,141 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2446,272,395 - 46,384,144 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605334,506,663 - 34,615,648 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dcaf5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473431,911,080 - 32,031,634 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dcaf5
375 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:541
Count of miRNA genes:281
Interacting mature miRNAs:341
Transcripts:ENSRNOT00000006005
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)683190345106747639Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat

Markers in Region
D6Got128  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2699,184,967 - 99,185,094 (+)MAPPERmRatBN7.2
mRatBN7.2699,181,714 - 99,181,865 (+)MAPPERmRatBN7.2
Rnor_6.06103,530,048 - 103,530,174NCBIRnor6.0
Rnor_6.06103,526,795 - 103,526,945NCBIRnor6.0
Rnor_5.06111,705,052 - 111,705,178UniSTSRnor5.0
Rnor_5.06111,701,799 - 111,701,949UniSTSRnor5.0
RGSC_v3.46103,376,172 - 103,376,298UniSTSRGSC3.4
RGSC_v3.46103,376,171 - 103,376,297RGDRGSC3.4
RGSC_v3.46103,372,918 - 103,373,068RGDRGSC3.4
RGSC_v3.46103,372,919 - 103,373,069UniSTSRGSC3.4
RGSC_v3.16103,379,627 - 103,379,753RGD
Celera697,537,766 - 97,537,910UniSTS
Celera697,541,013 - 97,541,139UniSTS
RH 3.4 Map6711.4RGD
RH 3.4 Map6711.4UniSTS
Cytogenetic Map6q24UniSTS
D6Got130  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2699,200,655 - 99,200,861 (+)MAPPERmRatBN7.2
Rnor_6.06103,545,735 - 103,545,940NCBIRnor6.0
Rnor_5.06111,720,739 - 111,720,944UniSTSRnor5.0
RGSC_v3.46103,391,859 - 103,392,064UniSTSRGSC3.4
RGSC_v3.46103,391,858 - 103,392,064RGDRGSC3.4
RGSC_v3.16103,395,315 - 103,395,520RGD
RH 3.4 Map6707.6UniSTS
RH 3.4 Map6707.6RGD
Cytogenetic Map6q24UniSTS
AI430035  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2699,171,552 - 99,171,739 (+)MAPPERmRatBN7.2
Rnor_6.06103,516,633 - 103,516,819NCBIRnor6.0
Rnor_5.06111,691,637 - 111,691,823UniSTSRnor5.0
RGSC_v3.46103,362,757 - 103,362,943UniSTSRGSC3.4
Celera697,527,604 - 97,527,790UniSTS
Cytogenetic Map6q24UniSTS
D14S848  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2699,174,193 - 99,174,526 (+)MAPPERmRatBN7.2
Rnor_6.06103,519,274 - 103,519,606NCBIRnor6.0
Rnor_5.06111,694,278 - 111,694,610UniSTSRnor5.0
RGSC_v3.46103,365,398 - 103,365,730UniSTSRGSC3.4
Celera697,530,245 - 97,530,577UniSTS
Cytogenetic Map6q24UniSTS
RH91357  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2699,174,880 - 99,175,003 (+)MAPPERmRatBN7.2
Rnor_6.06103,519,961 - 103,520,083NCBIRnor6.0
Rnor_5.06111,694,965 - 111,695,087UniSTSRnor5.0
RGSC_v3.46103,366,085 - 103,366,207UniSTSRGSC3.4
Celera697,530,932 - 97,531,054UniSTS
Cytogenetic Map6q24UniSTS
RH140793  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2699,171,599 - 99,171,749 (+)MAPPERmRatBN7.2
Rnor_6.06103,516,680 - 103,516,829NCBIRnor6.0
Rnor_5.06111,691,684 - 111,691,833UniSTSRnor5.0
RGSC_v3.46103,362,804 - 103,362,953UniSTSRGSC3.4
Celera697,527,651 - 97,527,800UniSTS
RH 3.4 Map6704.0UniSTS
Cytogenetic Map6q24UniSTS
BI281105  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2699,259,151 - 99,259,315 (+)MAPPERmRatBN7.2
Rnor_6.06103,604,298 - 103,604,461NCBIRnor6.0
Rnor_5.06111,779,302 - 111,779,465UniSTSRnor5.0
RGSC_v3.46103,450,628 - 103,450,791UniSTSRGSC3.4
Celera697,615,024 - 97,615,187UniSTS
RH 3.4 Map6711.0UniSTS
Cytogenetic Map6q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 37 45 29 19 29 8 11 74 35 41 11 8
Low 6 12 12 12
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000006005   ⟹   ENSRNOP00000006005
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl699,171,506 - 99,260,110 (-)Ensembl
Rnor_6.0 Ensembl6103,516,586 - 103,605,256 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000094678   ⟹   ENSRNOP00000097052
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl699,171,506 - 99,240,689 (-)Ensembl
RefSeq Acc Id: NM_001100718   ⟹   NP_001094188
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2699,171,506 - 99,260,110 (-)NCBI
Rnor_6.06103,516,586 - 103,605,256 (-)NCBI
Rnor_5.06111,691,590 - 111,780,260 (-)NCBI
Celera697,527,557 - 97,615,982 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240279   ⟹   XP_006240341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2699,171,507 - 99,260,183 (-)NCBI
Rnor_6.06103,516,587 - 103,605,285 (-)NCBI
Rnor_5.06111,691,590 - 111,780,260 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008764782   ⟹   XP_008763004
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2699,171,507 - 99,260,156 (-)NCBI
Rnor_6.06103,516,587 - 103,605,288 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594145   ⟹   XP_017449634
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2699,171,507 - 99,260,011 (-)NCBI
Rnor_6.06103,516,587 - 103,605,104 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001094188   ⟸   NM_001100718
- UniProtKB: G3V6K4 (UniProtKB/TrEMBL),   A6HCI8 (UniProtKB/TrEMBL),   A0A8I6AVX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240341   ⟸   XM_006240279
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AVX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763004   ⟸   XM_008764782
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AVX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449634   ⟸   XM_017594145
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AVX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000006005   ⟸   ENSRNOT00000006005
RefSeq Acc Id: ENSRNOP00000097052   ⟸   ENSRNOT00000094678

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V6K4-F1-model_v2 AlphaFold G3V6K4 1-946 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306535 AgrOrtholog
BioCyc Gene G2FUF-36936 BioCyc
Ensembl Genes ENSRNOG00000004556 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006005 ENTREZGENE
  ENSRNOT00000006005.7 UniProtKB/TrEMBL
  ENSRNOT00000094678 ENTREZGENE
  ENSRNOT00000094678.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7114611 IMAGE-MGC_LOAD
InterPro DCAF8 UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report rno:314273 UniProtKB/TrEMBL
MGC_CLONE MGC:94973 IMAGE-MGC_LOAD
NCBI Gene 314273 ENTREZGENE
PANTHER DDB1- AND CUL4-ASSOCIATED FACTOR 5 UniProtKB/TrEMBL
  PTHR15574 UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
PhenoGen Dcaf5 PhenoGen
PROSITE WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004556 RatGTEx
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP WD40_like UniProtKB/TrEMBL
UniProt A0A8I6AVX6 ENTREZGENE, UniProtKB/TrEMBL
  A6HCI8 ENTREZGENE, UniProtKB/TrEMBL
  G3V6K4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Dcaf5  DDB1 and CUL4 associated factor 5  LOC102553533  DDB1- and CUL4-associated factor 5-like  Data merged from RGD:7747023 737654 PROVISIONAL
2013-12-18 LOC102553533  DDB1- and CUL4-associated factor 5-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-05-05 Dcaf5  DDB1 and CUL4 associated factor 5  Wdr22  WD repeat domain 22  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Wdr22  WD repeat domain 22  Wdr22_predicted  WD repeat domain 22 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Wdr22_predicted  WD repeat domain 22 (predicted)      Symbol and Name status set to approved 70820 APPROVED