Gene: Fntb (farnesyltransferase, CAAX box, beta) Rattus norvegicus
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Symbol: Fntb
Name: farnesyltransferase, CAAX box, beta
Description: Exhibits protein farnesyltransferase activity; contributes to several functions, including drug binding activity, isoprenoid binding activity, and peptide binding activity; involved in several processes, including positive regulation of cell cycle, positive regulation of cell population proliferation, and positive regulation of nitric-oxide synthase biosynthetic process; localizes to the protein-containing complex; orthologous to human CHURC1-FNTB (CHURC1-FNTB readthrough) and FNTB (farnesyltransferase, CAAX box, beta); INTERACTS WITH (-)-perillyl alcohol; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2,4-trimethylbenzene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CAAX farnesyltransferase subunit beta; farnesyltransferase beta subunit; FTase-beta; MGC105303; protein farnesyltransferase subunit beta; ras proteins prenyltransferase subunit beta
Orthologs:
Homo sapiens (human) : FNTB (farnesyltransferase, CAAX box, beta)  HGNC  Alliance
Mus musculus (house mouse) : Fntb (farnesyltransferase, CAAX box, beta)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fntb (farnesyltransferase, CAAX box, beta)
Pan paniscus (bonobo/pygmy chimpanzee) : FNTB (farnesyltransferase, CAAX box, beta)
Canis lupus familiaris (dog) : FNTB (farnesyltransferase, CAAX box, beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fntb (farnesyltransferase, CAAX box, beta)
Sus scrofa (pig) : FNTB (farnesyltransferase, CAAX box, beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0699,883,959 - 99,966,988 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06109,278,424 - 109,361,572 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4699,427,967 - 99,511,373 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1699,431,422 - 99,514,829 (+)NCBI
Celera693,954,767 - 94,037,720 (+)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Fntb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620119
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.