Begain (brain-enriched guanylate kinase-associated) - Rat Genome Database

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Gene: Begain (brain-enriched guanylate kinase-associated) Rattus norvegicus
Analyze
Symbol: Begain
Name: brain-enriched guanylate kinase-associated
RGD ID: 708347
Description: Predicted to be involved in evoked excitatory postsynaptic potential and regulation of postsynaptic neurotransmitter receptor activity. Located in several cellular components, including dendrite; neuronal cell body; and synapse. Is active in glutamatergic synapse and postsynapse. Orthologous to human BEGAIN (brain enriched guanylate kinase associated); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: brain-enriched guanylate kinase-associated protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86133,708,010 - 133,744,264 (-)NCBIGRCr8
mRatBN7.26127,943,651 - 127,979,876 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6127,943,651 - 127,979,841 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6128,066,312 - 128,102,557 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06128,362,113 - 128,398,358 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06127,721,997 - 127,758,239 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06132,936,964 - 132,972,569 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6132,936,970 - 132,972,511 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06142,107,875 - 142,129,457 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46133,296,175 - 133,317,921 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16133,303,261 - 133,323,875 (+)NCBI
Celera6125,492,047 - 125,528,044 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (TAS)
dendrite  (IDA)
glutamatergic synapse  (IDA,ISO)
membrane  (IEA)
neuronal cell body  (IDA)
nucleus  (IDA)
postsynapse  (IDA)
presynapse  (ISO)
synapse  (IBA,IDA)

Molecular Function
protein binding  (IPI,ISO)

References

References - curated
# Reference Title Reference Citation
1. BEGAIN (brain-enriched guanylate kinase-associated protein), a novel neuronal PSD-95/SAP90-binding protein. Deguchi M, etal., J Biol Chem 1998 Oct 9;273(41):26269-72.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Synaptic and nuclear localization of brain-enriched guanylate kinase-associated protein. Yao I, etal., J Neurosci. 2002 Jul 1;22(13):5354-64.
Additional References at PubMed
PMID:22871113   PMID:27785460  


Genomics

Comparative Map Data
Begain
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86133,708,010 - 133,744,264 (-)NCBIGRCr8
mRatBN7.26127,943,651 - 127,979,876 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6127,943,651 - 127,979,841 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6128,066,312 - 128,102,557 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06128,362,113 - 128,398,358 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06127,721,997 - 127,758,239 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06132,936,964 - 132,972,569 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6132,936,970 - 132,972,511 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06142,107,875 - 142,129,457 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46133,296,175 - 133,317,921 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16133,303,261 - 133,323,875 (+)NCBI
Celera6125,492,047 - 125,528,044 (-)NCBICelera
Cytogenetic Map6q32NCBI
BEGAIN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814100,537,147 - 100,587,417 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14100,537,147 - 100,587,417 (-)EnsemblGRCh38hg38GRCh38
GRCh3714101,003,484 - 101,053,754 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3614100,073,240 - 100,105,884 (-)NCBINCBI36Build 36hg18NCBI36
Build 3414100,073,240 - 100,105,884NCBI
Celera1481,058,597 - 81,067,990 (-)NCBICelera
Cytogenetic Map14q32.2NCBI
HuRef1481,184,789 - 81,217,351 (-)NCBIHuRef
CHM1_114100,941,743 - 100,974,254 (-)NCBICHM1_1
T2T-CHM13v2.01494,770,948 - 94,821,230 (-)NCBIT2T-CHM13v2.0
Begain
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912108,998,107 - 109,034,168 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12108,998,113 - 109,034,143 (-)EnsemblGRCm39 Ensembl
GRCm3812109,032,181 - 109,068,242 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12109,032,187 - 109,068,217 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712110,270,392 - 110,306,427 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612109,479,989 - 109,535,141 (-)NCBIMGSCv36mm8
Celera12110,263,785 - 110,300,128 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1259.98NCBI
Begain
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543821,572,079 - 21,580,311 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543821,572,080 - 21,580,311 (-)NCBIChiLan1.0ChiLan1.0
BEGAIN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215101,688,579 - 101,740,523 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114100,905,073 - 100,957,017 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01481,157,642 - 81,209,503 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.114100,471,147 - 100,484,789 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14100,471,969 - 100,512,416 (-)Ensemblpanpan1.1panPan2
BEGAIN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1868,794,403 - 68,838,471 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl868,795,049 - 68,838,789 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha868,312,154 - 68,356,461 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0869,077,572 - 69,121,859 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl869,078,224 - 69,112,547 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1868,739,219 - 68,783,609 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0868,805,347 - 68,849,655 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0869,202,993 - 69,230,912 (-)NCBIUU_Cfam_GSD_1.0
Begain
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086405,904,482 - 5,919,740 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366044,162,658 - 4,195,815 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366044,162,728 - 4,195,540 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BEGAIN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7121,389,563 - 121,434,426 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17121,389,554 - 121,434,420 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27132,475,790 - 132,478,450 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BEGAIN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12478,501,920 - 78,552,954 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2478,501,870 - 78,511,496 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605365,640,475 - 65,690,691 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Begain
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247343,596,597 - 3,634,836 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247343,596,499 - 3,634,255 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Begain
97 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:90
Count of miRNA genes:73
Interacting mature miRNAs:77
Transcripts:ENSRNOT00000041903
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6104085867128713626Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6122549046140994061Rat
2312560Pur20Proteinuria QTL 202.10.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)6125628133137801795Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)6122549046137801795Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6112636280140994061Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6116506292130245370Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1300076Glom8Glomerulus QTL 879e-09kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6122549046140286318Rat

Markers in Region
D6Wox34  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26127,944,225 - 127,944,504 (+)MAPPERmRatBN7.2
Rnor_6.06132,937,539 - 132,937,817NCBIRnor6.0
Rnor_5.06142,108,450 - 142,108,728UniSTSRnor5.0
RGSC_v3.46133,317,068 - 133,317,346UniSTSRGSC3.4
Celera6125,492,622 - 125,492,900UniSTS
Cytogenetic Map6q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 87 86 55 25 55 6 214 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001111115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_024163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF064868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF064869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP478305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB801805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000041903   ⟹   ENSRNOP00000049699
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6127,943,651 - 127,965,397 (-)Ensembl
Rnor_6.0 Ensembl6132,936,970 - 132,958,546 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000082216   ⟹   ENSRNOP00000071412
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6127,943,651 - 127,979,841 (-)Ensembl
Rnor_6.0 Ensembl6132,937,891 - 132,972,511 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095766   ⟹   ENSRNOP00000088091
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6127,943,651 - 127,971,058 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117298   ⟹   ENSRNOP00000086294
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6127,943,651 - 127,951,189 (-)Ensembl
RefSeq Acc Id: NM_001111115   ⟹   NP_001104585
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,708,010 - 133,729,756 (-)NCBI
mRatBN7.26127,943,651 - 127,965,397 (-)NCBI
Rnor_6.06132,936,964 - 132,958,546 (-)NCBI
Rnor_5.06142,107,875 - 142,129,457 (-)NCBI
RGSC_v3.46133,296,175 - 133,317,921 (+)RGD
Celera6125,492,047 - 125,513,794 (-)NCBI
Sequence:
RefSeq Acc Id: NM_024163   ⟹   NP_077077
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,708,010 - 133,744,230 (-)NCBI
mRatBN7.26127,943,651 - 127,979,871 (-)NCBI
Rnor_6.06132,936,964 - 132,972,569 (-)NCBI
Rnor_5.06142,107,875 - 142,129,457 (-)NCBI
RGSC_v3.46133,296,175 - 133,317,921 (+)RGD
Celera6125,492,047 - 125,528,044 (-)RGD
Sequence:
RefSeq Acc Id: XM_017594386   ⟹   XP_017449875
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,708,011 - 133,744,240 (-)NCBI
mRatBN7.26127,943,651 - 127,979,823 (-)NCBI
Rnor_6.06132,936,964 - 132,972,539 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112981   ⟹   XP_038968909
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,708,011 - 133,744,242 (-)NCBI
mRatBN7.26127,943,651 - 127,979,823 (-)NCBI
RefSeq Acc Id: XM_039112984   ⟹   XP_038968912
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,708,011 - 133,729,710 (-)NCBI
mRatBN7.26127,943,651 - 127,965,335 (-)NCBI
RefSeq Acc Id: XM_039112985   ⟹   XP_038968913
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,708,011 - 133,744,264 (-)NCBI
mRatBN7.26127,943,651 - 127,979,876 (-)NCBI
RefSeq Acc Id: XM_039112986   ⟹   XP_038968914
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,708,011 - 133,729,569 (-)NCBI
mRatBN7.26127,943,651 - 127,965,292 (-)NCBI
RefSeq Acc Id: XM_039112987   ⟹   XP_038968915
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,708,011 - 133,729,778 (-)NCBI
mRatBN7.26127,943,651 - 127,965,402 (-)NCBI
RefSeq Acc Id: XM_039112988   ⟹   XP_038968916
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,708,011 - 133,730,352 (-)NCBI
mRatBN7.26127,943,651 - 127,966,007 (-)NCBI
RefSeq Acc Id: XM_039112990   ⟹   XP_038968918
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,708,011 - 133,717,141 (-)NCBI
mRatBN7.26127,943,651 - 127,952,830 (-)NCBI
RefSeq Acc Id: XM_063262539   ⟹   XP_063118609
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,708,011 - 133,725,355 (-)NCBI
RefSeq Acc Id: XM_063262540   ⟹   XP_063118610
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,708,011 - 133,729,097 (-)NCBI
RefSeq Acc Id: XM_063262541   ⟹   XP_063118611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,708,011 - 133,725,354 (-)NCBI
RefSeq Acc Id: XM_063262542   ⟹   XP_063118612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,708,011 - 133,729,679 (-)NCBI
RefSeq Acc Id: XM_063262543   ⟹   XP_063118613
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,708,011 - 133,729,126 (-)NCBI
RefSeq Acc Id: XM_063262544   ⟹   XP_063118614
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,708,011 - 133,744,264 (-)NCBI
RefSeq Acc Id: XM_063262545   ⟹   XP_063118615
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,708,011 - 133,744,224 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001104585 (Get FASTA)   NCBI Sequence Viewer  
  NP_077077 (Get FASTA)   NCBI Sequence Viewer  
  XP_017449875 (Get FASTA)   NCBI Sequence Viewer  
  XP_038968909 (Get FASTA)   NCBI Sequence Viewer  
  XP_038968912 (Get FASTA)   NCBI Sequence Viewer  
  XP_038968913 (Get FASTA)   NCBI Sequence Viewer  
  XP_038968914 (Get FASTA)   NCBI Sequence Viewer  
  XP_038968915 (Get FASTA)   NCBI Sequence Viewer  
  XP_038968916 (Get FASTA)   NCBI Sequence Viewer  
  XP_038968918 (Get FASTA)   NCBI Sequence Viewer  
  XP_063118609 (Get FASTA)   NCBI Sequence Viewer  
  XP_063118610 (Get FASTA)   NCBI Sequence Viewer  
  XP_063118611 (Get FASTA)   NCBI Sequence Viewer  
  XP_063118612 (Get FASTA)   NCBI Sequence Viewer  
  XP_063118613 (Get FASTA)   NCBI Sequence Viewer  
  XP_063118614 (Get FASTA)   NCBI Sequence Viewer  
  XP_063118615 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC63267 (Get FASTA)   NCBI Sequence Viewer  
  AAC63268 (Get FASTA)   NCBI Sequence Viewer  
  EDL97539 (Get FASTA)   NCBI Sequence Viewer  
  EDL97540 (Get FASTA)   NCBI Sequence Viewer  
  EDL97541 (Get FASTA)   NCBI Sequence Viewer  
  EDL97542 (Get FASTA)   NCBI Sequence Viewer  
  EDL97543 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000049699
  ENSRNOP00000049699.3
  ENSRNOP00000071412
  ENSRNOP00000071412.2
  ENSRNOP00000086294.1
  ENSRNOP00000088091.1
  ENSRNOP00000099151
  ENSRNOP00000099634
  ENSRNOP00000100911
  ENSRNOP00000102527
  ENSRNOP00000104689
GenBank Protein O88881 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_077077   ⟸   NM_024163
- Peptide Label: isoform 2
- UniProtKB: O88882 (UniProtKB/Swiss-Prot),   O88881 (UniProtKB/Swiss-Prot),   A6KBI9 (UniProtKB/TrEMBL),   A0A0G2K0E5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001104585   ⟸   NM_001111115
- Peptide Label: isoform 1
- UniProtKB: A6KBJ0 (UniProtKB/TrEMBL),   A0A0G2K0E5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449875   ⟸   XM_017594386
- Peptide Label: isoform X7
- UniProtKB: A0A0G2K0E5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071412   ⟸   ENSRNOT00000082216
Ensembl Acc Id: ENSRNOP00000049699   ⟸   ENSRNOT00000041903
RefSeq Acc Id: XP_038968913   ⟸   XM_039112985
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K0E5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968909   ⟸   XM_039112981
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K0E5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968916   ⟸   XM_039112988
- Peptide Label: isoform X8
- UniProtKB: A0A0G2K0E5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968915   ⟸   XM_039112987
- Peptide Label: isoform X6
- UniProtKB: A0A0G2K0E5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968912   ⟸   XM_039112984
- Peptide Label: isoform X3
- UniProtKB: A0A0G2K0E5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968914   ⟸   XM_039112986
- Peptide Label: isoform X5
- UniProtKB: A0A0G2K0E5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968918   ⟸   XM_039112990
- Peptide Label: isoform X1
- UniProtKB: A6KBJ1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000086294   ⟸   ENSRNOT00000117298
Ensembl Acc Id: ENSRNOP00000088091   ⟸   ENSRNOT00000095766
RefSeq Acc Id: XP_063118614   ⟸   XM_063262544
- Peptide Label: isoform X12
- UniProtKB: A0A0G2K0E5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118615   ⟸   XM_063262545
- Peptide Label: isoform X1
- UniProtKB: A6KBJ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118612   ⟸   XM_063262542
- Peptide Label: isoform X10
- UniProtKB: A0A0G2K0E5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118613   ⟸   XM_063262543
- Peptide Label: isoform X11
- UniProtKB: A0A0G2K0E5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118610   ⟸   XM_063262540
- Peptide Label: isoform X8
- UniProtKB: A0A0G2K0E5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118609   ⟸   XM_063262539
- Peptide Label: isoform X1
- UniProtKB: A6KBJ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118611   ⟸   XM_063262541
- Peptide Label: isoform X9
- UniProtKB: A6KBJ1 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88881-F1-model_v2 AlphaFold O88881 1-611 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708347 AgrOrtholog
BioCyc Gene G2FUF-36270 BioCyc
Ensembl Genes ENSRNOG00000004650 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000041903 ENTREZGENE
  ENSRNOT00000041903.6 UniProtKB/Swiss-Prot
  ENSRNOT00000082216 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000082216.2 UniProtKB/Swiss-Prot
  ENSRNOT00000095766.1 UniProtKB/TrEMBL
  ENSRNOT00000117298.1 UniProtKB/TrEMBL
  ENSRNOT00000140322 ENTREZGENE
  ENSRNOT00000152282 ENTREZGENE
  ENSRNOT00000158669 ENTREZGENE
  ENSRNOT00000161251 ENTREZGENE
  ENSRNOT00000168582 ENTREZGENE
InterPro Tjap1/BEGAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:79146 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 79146 ENTREZGENE
PANTHER PTHR28664 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR28664:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Begain PhenoGen
RatGTEx ENSRNOG00000004650 RatGTEx
UniProt A0A0G2K0E5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AA22_RAT UniProtKB/TrEMBL
  A0A8I6GDW4_RAT UniProtKB/TrEMBL
  A6KBI8_RAT UniProtKB/TrEMBL
  A6KBI9 ENTREZGENE, UniProtKB/TrEMBL
  A6KBJ0 ENTREZGENE, UniProtKB/TrEMBL
  A6KBJ1 ENTREZGENE, UniProtKB/TrEMBL
  A6KBJ2_RAT UniProtKB/TrEMBL
  BEGIN_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  O88882 ENTREZGENE
UniProt Secondary O88882 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-12-14 Begain  brain-enriched guanylate kinase-associated      Symbol and Name status set to approved 1299863 APPROVED