Cm77 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Cm77 (Cardiac mass QTL 77) Rattus norvegicus

Symbol: Cm77
Name: Cardiac mass QTL 77
RGD ID: 6893340
Trait: heart mass   (VT:0007028)    
Measurement Type: heart weight to body weight ratio   (CMO:0000074)    
LOD Score: 0.26
P Value: 0.57
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8639,028,659 - 86,867,923RGD_MAPPER_PIPELINE
mRatBN7.2633,309,549 - 81,132,889RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0636,260,288 - 84,763,275RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0646,021,394 - 94,275,468RGDRnor5.0
RGSC_v3.4634,039,461 - 84,287,190RGDRGSC3.4
Cross Type: Not Available
Strains Crossed: WKY/Tkyo SHR/Tkyo 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm77RatLeft Ventricular Hypertrophy  IAGP 1554311 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm77Ratincreased heart weight  IDA 1554311 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm77Ratheart weight to body weight ratio  IDA 1554311originally annotated as CMO:0000075 and heart weight as percentage of body weightRGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm77Ratcontrolled sodium content diet  IDA 1554311 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm77Ratpost excision weight measurement  IDA 1554311 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm77RatSHR/Tkyo  IEA 1554311 RGD 
Cm77RatWKY/Tkyo  IEA 1554311 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm77Ratheart mass  IDA 1554311 RGD 


#
Reference Title
Reference Citation
1. Identification of quantitative trait loci for cardiac hypertrophy in two different strains of the spontaneously hypertensive rat. Inomata H, etal., Hypertens Res 2005 Mar;28(3):273-81.


1 to 20 of 440 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
41370558LOC120103512uncharacterized LOC12010351263325562533325526Rat
41281285LOC120103513uncharacterized LOC12010351363344774633451185Rat
6494941Parl-ps7presenilin associated, rhomboid-like, pseudogene 763377856133782700Rat
621527Kcns3potassium voltage-gated channel, modifier subfamily S, member 363380831433865018Rat
1587516Msgn1mesogenin 163391278733913427Rat
1559792Gen1GEN1 Holliday junction 5' flap endonuclease63394759933978461Rat
7591084LOC102547959uncharacterized LOC10254795963395953233962509Rat
1311214Smc6structural maintenance of chromosomes 663397873034033201Rat
3966Vsnl1visinin-like 163403864134159479Rat
1583700Mrps10-ps1mitochondrial ribosomal protein S10, pseudogene 163417823034178737Rat
2322652Rad51ap2RAD51 associated protein 263418217734189129Rat
1586345Hspa8-ps25heat shock protein family A (Hsp70) member 8, pseudogene 2563462402634626138Rat
41331744LOC120093456small nucleolar RNA SNORA1763476947034769595Rat
1586329Hat1-ps1histone acetyltransferase 1, pseudogene 163484247134843593Rat
1586335Rpl27l8ribosomal protein L27 like 863486773334868179Rat
1305961CyriaCYFIP related Rac1 interactor A63504520835150669Rat
2322296Cox7cl1cytochrome c oxidase subunit 7C like 163532699535327273Rat
1565679Rpl27a-ps14ribosomal protein L27a, pseudogene 1463550127535501755Rat
11364133Trnav-uac3transfer RNA valine (anticodon UAC) 363558021135580283Rat
41335282LOC120093419small nucleolar RNA SNORA1563559727935597405Rat

1 to 20 of 440 rows
1 to 20 of 568 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
11141D6Arb1230364865776548658068Ratregion
11241D6Mit311767220263272202749Ratregion
11241D6Mit311767222752472227641Ratregion
11242D6Arb1738967220263372203021Ratregion
11242D6Arb1738967222725172227640Ratregion
33828D6Mit915863330939133309549Ratregion
33977D6Mit424665773029457730540Ratregion
33993D6Mit214768113288981133036Ratregion
34072D6Mgh717764579008845790265Ratregion
34306D6Mgh59667346336373463459Ratregion
11347D6Wox1824267583645575836697Ratregion
11488D6Arb721963403955034039769Ratregion
37222D6Rat8221764298481642985033Ratregion
37392D6Rat9323064343264943432879Ratregion
35235D6Rat2913063813689338137023Ratregion
35338D6Rat3116264234207842342232Ratregion
35390D6Rat3614063509870935098849Ratregion
35396D6Rat3516863443413734434305Ratregion
35531D6Rat3815163403951834039669Ratregion
36813D6Rat2015867877764178777799Ratregion
1 to 20 of 568 rows

Flank 1: (D6Mit2)
Rat AssemblyChrPosition (strand)Source
GRCr8686,867,923 - 86,868,070 (+)Marker Load Pipeline
mRatBN7.2681,132,889 - 81,133,036 (+)MAPPER
Rnor_6.0684,763,275 - 84,763,421NCBI
Rnor_5.0694,275,468 - 94,275,614UniSTS
RGSC_v3.4684,287,190 - 84,287,337RGD
RGSC_v3.4684,287,191 - 84,287,337UniSTS
RGSC_v3.1684,290,646 - 84,290,793RGD
Celera679,755,506 - 79,755,652UniSTS
RH 3.4 Map6554.0UniSTS
RH 3.4 Map6554.0RGD
RH 2.0 Map6798.9RGD
SHRSP x BN Map652.2299RGD
Cytogenetic Map6 RGD
Peak: (D6Mit4)
Rat AssemblyChrPosition (strand)Source
GRCr8663,457,441 - 63,457,687 (+)Marker Load Pipeline
mRatBN7.2657,730,294 - 57,730,540 (+)MAPPER
Rnor_6.0660,606,186 - 60,606,431NCBI
Rnor_5.0670,193,933 - 70,194,178UniSTS
RGSC_v3.4659,946,628 - 59,946,874RGD
RGSC_v3.4659,946,629 - 59,946,874UniSTS
RGSC_v3.1659,949,755 - 59,950,000RGD
RH 3.4 Map6406.6RGD
RH 3.4 Map6406.6UniSTS
RH 2.0 Map6589.2RGD
Cytogenetic Map6q21UniSTS
Flank 2: (D6Mit9)
Rat AssemblyChrPosition (strand)Source
GRCr8639,028,501 - 39,028,659 (+)Marker Load Pipeline
mRatBN7.2633,309,391 - 33,309,549 (+)MAPPER
Rnor_6.0636,260,131 - 36,260,288NCBI
Rnor_5.0646,021,237 - 46,021,394UniSTS
RGSC_v3.4634,039,303 - 34,039,461RGD
RGSC_v3.4634,039,304 - 34,039,461UniSTS
RGSC_v3.1634,042,257 - 34,042,414RGD
Celera632,744,086 - 32,744,243UniSTS
RH 3.4 Map6123.2UniSTS
RH 3.4 Map6123.2RGD
RH 2.0 Map6277.3RGD
SHRSP x BN Map628.5599RGD
Cytogenetic Map6 RGD


1 to 10 of 59 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
8693632Alc27Alcohol consumption QTL 272.20.791drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)63432335751121479Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)6134235784Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat
1578758Tcas9Tongue tumor susceptibility QTL 93.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)6137618905Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat

1 to 10 of 59 rows


Note Type Note Reference
qtl_general software used: MAPMAKER/QTL 1.1 1554311
qtl_general number of animals used: 151 F2 males 1554311