Dnajb9 (DnaJ heat shock protein family (Hsp40) member B9) - Rat Genome Database

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Gene: Dnajb9 (DnaJ heat shock protein family (Hsp40) member B9) Rattus norvegicus
Analyze
Symbol: Dnajb9
Name: DnaJ heat shock protein family (Hsp40) member B9
RGD ID: 3070
Description: Predicted to enable Hsp70 protein binding activity and misfolded protein binding activity. Predicted to be involved in several processes, including ERAD pathway; negative regulation of IRE1-mediated unfolded protein response; and positive regulation of immunoglobulin production. Located in cytoplasm and nucleolus. Orthologous to human DNAJB9 (DnaJ heat shock protein family (Hsp40) member B9); INTERACTS WITH (+)-schisandrin B; 1,4-dithiothreitol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: DnaJ (Hsp40) homolog subfamily B member 9; DnaJ (Hsp40) homolog, subfamily B, member 9; dnaJ homolog subfamily B member 9; dnaJ homolog, subfamily b, member 9; endoplasmic reticulum DNA J domain-containing protein 4; ER-resident protein ERdj4; ERdj4; mdg-1; Mdg1; Microvascular endothelial differentiation gene 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8666,997,842 - 67,007,371 (-)NCBIGRCr8
mRatBN7.2661,270,385 - 61,276,795 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl661,269,913 - 61,275,063 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx661,606,994 - 61,611,192 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0661,921,985 - 61,926,183 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0661,394,475 - 61,398,675 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0664,165,913 - 64,170,122 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl664,165,913 - 64,170,151 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0673,754,560 - 73,770,497 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4663,583,033 - 63,587,247 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1663,586,159 - 63,590,373 (-)NCBI
Celera660,267,249 - 60,271,433 (-)NCBICelera
Cytogenetic Map6q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-dithiothreitol  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
1H-pyrazole  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-diaminotoluene  (ISO)
2,6-dinitrotoluene  (EXP)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,4-dichloroaniline  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-phenylbutyric acid  (ISO)
8-Br-cAMP  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
Aroclor 1254  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
atazanavir sulfate  (ISO)
avobenzone  (ISO)
azoxystrobin  (EXP)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-D-glucosamine  (ISO)
beta-lapachone  (ISO)
bicalutamide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbaryl  (ISO)
carbon nanotube  (ISO)
chenodeoxycholic acid  (ISO)
chloroacetaldehyde  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (EXP)
cidofovir anhydrous  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (EXP)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
CU-O LINKAGE  (ISO)
curcumin  (ISO)
cyclosporin A  (EXP,ISO)
DDE  (ISO)
deguelin  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dichloromethane  (ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
Didecyldimethylammonium  (ISO)
dieldrin  (EXP)
dimethyl sulfoxide  (EXP)
dimethylarsinous acid  (ISO)
dinophysistoxin 1  (ISO)
dioxygen  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP)
elesclomol  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
epoxiconazole  (ISO)
ethyl methanesulfonate  (ISO)
ethylbenzene  (ISO)
fenofibrate  (EXP)
flavonoids  (EXP)
fluoranthene  (ISO)
fluoxetine  (EXP)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glyphosate  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
hydroquinone O-beta-D-glucopyranoside  (ISO)
ifosfamide  (ISO)
imidacloprid  (EXP)
indometacin  (ISO)
iron dichloride  (ISO)
isoflavones  (ISO)
isoprenaline  (ISO)
L-1,4-dithiothreitol  (EXP)
L-serine  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
luteolin  (ISO)
mercury dichloride  (EXP)
metformin  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
methylseleninic acid  (ISO)
mifepristone  (ISO)
N-acetyl-L-cysteine  (ISO)
nefazodone  (EXP,ISO)
nickel dichloride  (ISO)
nicotine  (ISO)
nimesulide  (EXP)
o-xylene  (ISO)
organoselenium compound  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
propiconazole  (ISO)
quinolin-8-ol  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
senecionine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tartrazine  (ISO)
tetrachloromethane  (EXP,ISO)
thalidomide  (ISO)
thapsigargin  (EXP,ISO)
thiabendazole  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
toluene  (ISO)
triadimefon  (ISO)
Tributyltin oxide  (EXP)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (EXP)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. High levels of the molecular chaperone Mdg1/ERdj4 reflect the activation state of endothelial cells. Berger BJ, etal., Exp Cell Res 2003 Oct 15;290(1):82-92.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Upregulation of the cochaperone Mdg1 in endothelial cells is induced by stress and during in vitro angiogenesis. Prols F, etal., Exp Cell Res 2001 Sep 10;269(1):42-53.
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:11836248   PMID:15489334   PMID:18400946   PMID:19199708   PMID:21231916   PMID:22267725   PMID:25222125  


Genomics

Comparative Map Data
Dnajb9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8666,997,842 - 67,007,371 (-)NCBIGRCr8
mRatBN7.2661,270,385 - 61,276,795 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl661,269,913 - 61,275,063 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx661,606,994 - 61,611,192 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0661,921,985 - 61,926,183 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0661,394,475 - 61,398,675 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0664,165,913 - 64,170,122 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl664,165,913 - 64,170,151 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0673,754,560 - 73,770,497 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4663,583,033 - 63,587,247 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1663,586,159 - 63,590,373 (-)NCBI
Celera660,267,249 - 60,271,433 (-)NCBICelera
Cytogenetic Map6q21NCBI
DNAJB9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387108,569,874 - 108,574,850 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7108,569,867 - 108,574,850 (+)EnsemblGRCh38hg38GRCh38
GRCh377108,210,318 - 108,215,294 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367107,997,592 - 108,002,530 (+)NCBINCBI36Build 36hg18NCBI36
Build 347107,804,306 - 107,809,245NCBI
Celera7103,023,727 - 103,028,665 (+)NCBICelera
Cytogenetic Map7q31.1NCBI
HuRef7102,578,406 - 102,583,511 (+)NCBIHuRef
CHM1_17108,143,475 - 108,148,580 (+)NCBICHM1_1
T2T-CHM13v2.07109,894,482 - 109,899,458 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27107,577,403 - 107,582,508 (+)NCBI
Dnajb9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391244,252,680 - 44,256,851 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1244,252,342 - 44,257,109 (-)EnsemblGRCm39 Ensembl
GRCm381244,205,897 - 44,210,068 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1244,205,559 - 44,210,326 (-)EnsemblGRCm38mm10GRCm38
MGSCv371245,306,884 - 45,311,055 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361245,076,183 - 45,080,354 (-)NCBIMGSCv36mm8
Celera1245,576,005 - 45,580,176 (-)NCBICelera
Cytogenetic Map12B2NCBI
cM Map1220.71NCBI
Dnajb9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541012,814,479 - 12,822,777 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541012,814,993 - 12,820,852 (+)NCBIChiLan1.0ChiLan1.0
DNAJB9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26145,419,483 - 145,424,301 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17193,689,453 - 193,694,271 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07100,555,527 - 100,560,052 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17113,273,844 - 113,279,105 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7113,274,015 - 113,279,105 (+)Ensemblpanpan1.1panPan2
DNAJB9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11448,879,963 - 48,885,616 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1448,879,914 - 48,884,361 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1448,323,737 - 48,329,124 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01448,829,357 - 48,834,752 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1448,829,970 - 48,834,742 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11448,926,451 - 48,931,836 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01448,610,313 - 48,615,689 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01448,983,891 - 48,989,289 (+)NCBIUU_Cfam_GSD_1.0
Dnajb9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511868,402,977 - 68,407,460 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366531,554,553 - 1,559,170 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366531,554,534 - 1,558,832 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAJB9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1836,579,453 - 36,584,130 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11836,578,928 - 36,584,211 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21840,219,853 - 40,224,716 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DNAJB9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12177,477,177 - 77,482,190 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2177,479,112 - 77,482,571 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604226,381,126 - 26,386,050 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnajb9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473921,187,581 - 21,193,337 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473921,187,581 - 21,193,345 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dnajb9
36 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:109
Count of miRNA genes:87
Interacting mature miRNAs:90
Transcripts:ENSRNOT00000005363
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)65672856290198260Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)62033877762613667Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat

Markers in Region
RH140278  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2661,271,115 - 61,271,332 (+)MAPPERmRatBN7.2
Rnor_6.0664,166,175 - 64,166,391NCBIRnor6.0
Rnor_5.0673,754,822 - 73,755,038UniSTSRnor5.0
RGSC_v3.4663,583,295 - 63,583,511UniSTSRGSC3.4
Celera660,267,511 - 60,267,727UniSTS
RH 3.4 Map6433.3UniSTS
Cytogenetic Map6q16-q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000005363   ⟹   ENSRNOP00000005363
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl661,269,913 - 61,275,063 (-)Ensembl
Rnor_6.0 Ensembl664,165,913 - 64,170,151 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093248   ⟹   ENSRNOP00000076154
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl664,167,798 - 64,170,122 (-)Ensembl
RefSeq Acc Id: NM_012699   ⟹   NP_036831
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8666,997,842 - 67,002,051 (-)NCBI
mRatBN7.2661,270,854 - 61,275,063 (-)NCBI
Rnor_6.0664,165,913 - 64,170,122 (-)NCBI
Rnor_5.0673,754,560 - 73,770,497 (-)NCBI
RGSC_v3.4663,583,033 - 63,587,247 (-)RGD
Celera660,267,249 - 60,271,433 (-)RGD
Sequence:
RefSeq Acc Id: XM_039111791   ⟹   XP_038967719
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8666,997,842 - 67,007,371 (-)NCBI
mRatBN7.2661,270,385 - 61,276,795 (-)NCBI
Protein Sequences
Protein RefSeqs NP_036831 (Get FASTA)   NCBI Sequence Viewer  
  XP_038967719 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH70915 (Get FASTA)   NCBI Sequence Viewer  
  CAA67434 (Get FASTA)   NCBI Sequence Viewer  
  EDM03348 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000005363.3
  ENSRNOP00055027291
  ENSRNOP00060005785
  ENSRNOP00065011387
GenBank Protein P97554 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_036831   ⟸   NM_012699
- Peptide Label: precursor
- UniProtKB: P97554 (UniProtKB/Swiss-Prot),   A6HBE3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000005363   ⟸   ENSRNOT00000005363
Ensembl Acc Id: ENSRNOP00000076154   ⟸   ENSRNOT00000093248
RefSeq Acc Id: XP_038967719   ⟸   XM_039111791
- Peptide Label: isoform X1
Protein Domains
J

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97554-F1-model_v2 AlphaFold P97554 1-222 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694575
Promoter ID:EPDNEW_R5100
Type:initiation region
Name:Dnajb9_1
Description:DnaJ heat shock protein family member B9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0664,170,122 - 64,170,182EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3070 AgrOrtholog
BioCyc Gene G2FUF-37710 BioCyc
Ensembl Genes ENSRNOG00000004006 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00055019714 UniProtKB/Swiss-Prot
  ENSRNOG00060004629 UniProtKB/Swiss-Prot
  ENSRNOG00065009492 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000005363.6 UniProtKB/Swiss-Prot
  ENSRNOT00055033641 UniProtKB/Swiss-Prot
  ENSRNOT00060007720 UniProtKB/Swiss-Prot
  ENSRNOT00065015185 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.287.110 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7104653 IMAGE-MGC_LOAD
InterPro DnaJ_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DnaJ_domain_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hsp70_co-chaperone_J-domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  J_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24908 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:91708 IMAGE-MGC_LOAD
NCBI Gene 24908 ENTREZGENE
PANTHER DNAJ HOMOLOG SUBFAMILY B MEMBER 9 UniProtKB/Swiss-Prot
  DNAJ HOMOLOG SUBFAMILY B MEMBER 9 UniProtKB/Swiss-Prot
  DNAJ HOMOLOG SUBFAMILY B MEMBER 9 UniProtKB/TrEMBL
  DNAJ HOMOLOG SUBFAMILY B MEMBER 9 UniProtKB/TrEMBL
Pfam DnaJ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dnajb9 PhenoGen
PRINTS JDOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE DNAJ_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNAJ_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004006 RatGTEx
  ENSRNOG00055019714 RatGTEx
  ENSRNOG00060004629 RatGTEx
  ENSRNOG00065009492 RatGTEx
SMART DnaJ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Chaperone J-domain UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
TIGR TC229679
UniProt A6HBE3 ENTREZGENE, UniProtKB/TrEMBL
  DNJB9_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Dnajb9  DnaJ heat shock protein family (Hsp40) member B9  Dnajb9  DnaJ (Hsp40) homolog, subfamily B, member 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Dnajb9  DnaJ (Hsp40) homolog, subfamily B, member 9    dnaJ homolog, subfamily b, member 9  Name updated 1299863 APPROVED
2002-06-10 Dnajb9  dnaJ homolog, subfamily b, member 9      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localizes to the cytoplasm, nucleus and nucleoli 1300442
gene_cellular_localization translocates to the nucleus after stress 1300442
gene_domains contains a J-domain 1300442
gene_function mammalian chaperone 1300443
gene_process protects endoplasmic reticulum stressed cells from apoptosis 1300443
gene_product member of the HSP40 protein family 1300443
gene_regulation upregulated in primary endothelial and mesangial cells by stress 1300442