Strn3 (striatin 3) - Rat Genome Database

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Gene: Strn3 (striatin 3) Rattus norvegicus
Analyze
Symbol: Strn3
Name: striatin 3
RGD ID: 621827
Description: Predicted to enable armadillo repeat domain binding activity; calmodulin binding activity; and enzyme binding activity. Involved in negative regulation of DNA-templated transcription; negative regulation of intracellular estrogen receptor signaling pathway; and response to estradiol. Located in cytoplasm; dendrite; and neuronal cell body. Part of protein-containing complex. Orthologous to human STRN3 (striatin 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cell cycle autoantigen SG2NA; cell-cycle autoantigen SG2NA; Gs2na; nuclear autoantigen; s/G2 antigen; Sg2na; striatin, calmodulin binding protein 3; striatin-3; striatin-3-gamma
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2669,047,776 - 69,134,102 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl669,047,776 - 69,134,102 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx669,469,929 - 69,554,311 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0669,776,579 - 69,860,949 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0669,216,069 - 69,300,471 (-)NCBIRnor_WKY
Rnor_6.0672,376,360 - 72,462,676 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl672,376,330 - 72,462,658 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0681,940,489 - 82,026,830 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4671,708,959 - 71,795,287 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1671,733,236 - 71,798,385 (-)NCBI
Celera667,923,577 - 68,009,729 (-)NCBICelera
Cytogenetic Map6q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Molecular cloning and characterization of phocein, a protein found from the Golgi complex to dendritic spines. Baillat G, etal., Mol Biol Cell 2001 Mar;12(3):663-73.
2. Expression and distribution of phocein and members of the striatin family in neurones of rat peripheral ganglia. Blondeau C, etal., Histochem Cell Biol. 2003 Feb;119(2):131-8. Epub 2003 Feb 7.
3. Zinedin, SG2NA, and striatin are calmodulin-binding, WD repeat proteins principally expressed in the brain. Castets F, etal., J Biol Chem. 2000 Jun 30;275(26):19970-7.
4. Targeting of proteins of the striatin family to dendritic spines: role of the coiled-coil domain. Gaillard S, etal., Traffic. 2006 Jan;7(1):74-84.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Striatin-3 gamma inhibits estrogen receptor activity by recruiting a protein phosphatase. Tan B, etal., J Mol Endocrinol. 2008 May;40(5):199-210.
10. Transcription activating property of autoantigen SG2NA and modulating effect of WD-40 repeats. Zhu W, etal., Exp Cell Res 2001 Oct 1;269(2):312-21.
Additional References at PubMed
PMID:11707266   PMID:18502210   PMID:18782753   PMID:25743393  


Genomics

Comparative Map Data
Strn3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2669,047,776 - 69,134,102 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl669,047,776 - 69,134,102 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx669,469,929 - 69,554,311 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0669,776,579 - 69,860,949 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0669,216,069 - 69,300,471 (-)NCBIRnor_WKY
Rnor_6.0672,376,360 - 72,462,676 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl672,376,330 - 72,462,658 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0681,940,489 - 82,026,830 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4671,708,959 - 71,795,287 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1671,733,236 - 71,798,385 (-)NCBI
Celera667,923,577 - 68,009,729 (-)NCBICelera
Cytogenetic Map6q23NCBI
STRN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381430,893,804 - 31,026,379 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1430,893,799 - 31,026,401 (-)EnsemblGRCh38hg38GRCh38
GRCh371431,363,010 - 31,495,585 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361430,432,756 - 30,565,358 (-)NCBINCBI36Build 36hg18NCBI36
Build 341430,432,760 - 30,565,340NCBI
Celera1411,228,456 - 11,361,095 (-)NCBICelera
Cytogenetic Map14q12NCBI
HuRef1411,480,100 - 11,613,295 (-)NCBIHuRef
CHM1_11431,362,176 - 31,494,809 (-)NCBICHM1_1
T2T-CHM13v2.01425,091,284 - 25,224,212 (-)NCBIT2T-CHM13v2.0
Strn3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391251,655,324 - 51,743,942 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1251,656,415 - 51,738,680 (-)EnsemblGRCm39 Ensembl
GRCm381251,608,541 - 51,692,351 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1251,609,632 - 51,691,897 (-)EnsemblGRCm38mm10GRCm38
MGSCv371252,709,528 - 52,792,901 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361252,531,252 - 52,613,506 (-)NCBIMGSCv36mm8
Celera1252,911,780 - 52,995,322 (-)NCBICelera
Cytogenetic Map12B3NCBI
Strn3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540929,529,507 - 29,636,674 (+)NCBIChiLan1.0ChiLan1.0
STRN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11429,867,827 - 29,997,439 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1429,869,414 - 29,997,838 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01411,668,426 - 11,798,776 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
STRN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1810,232,436 - 10,344,238 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl810,233,819 - 10,344,033 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha810,158,821 - 10,270,764 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0810,333,369 - 10,445,481 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl810,333,467 - 10,445,613 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1810,017,584 - 10,129,196 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0810,093,760 - 10,205,585 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0810,369,298 - 10,489,929 (-)NCBIUU_Cfam_GSD_1.0
Strn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864042,129,196 - 42,216,166 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364945,635,870 - 5,722,123 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STRN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl768,470,877 - 68,577,273 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1768,470,761 - 68,577,272 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Strn3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248201,264,200 - 1,366,342 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248201,264,267 - 1,364,634 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
D6Rat130  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2669,116,420 - 69,116,571 (+)MAPPERmRatBN7.2
Rnor_6.0672,444,999 - 72,445,149NCBIRnor6.0
Rnor_5.0682,009,158 - 82,009,308UniSTSRnor5.0
RGSC_v3.4671,777,628 - 71,777,778UniSTSRGSC3.4
Celera667,992,267 - 67,992,425UniSTS
RH 3.4 Map6497.4UniSTS
RH 3.4 Map6497.4RGD
RH 2.0 Map6660.8RGD
SHRSP x BN Map644.2699RGD
Cytogenetic Map6q22UniSTS
BE107927  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2669,134,763 - 69,134,919 (+)MAPPERmRatBN7.2
Rnor_6.0672,463,338 - 72,463,493NCBIRnor6.0
Rnor_5.0682,027,497 - 82,027,652UniSTSRnor5.0
RGSC_v3.4671,795,967 - 71,796,122UniSTSRGSC3.4
Celera668,010,391 - 68,010,546UniSTS
RH 3.4 Map6507.2UniSTS
Cytogenetic Map6q22UniSTS
AI228304  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2669,068,335 - 69,068,498 (+)MAPPERmRatBN7.2
Rnor_6.0672,396,919 - 72,397,081NCBIRnor6.0
Rnor_5.0681,961,079 - 81,961,241UniSTSRnor5.0
RGSC_v3.4671,729,549 - 71,729,711UniSTSRGSC3.4
Celera667,944,136 - 67,944,298UniSTS
RH 3.4 Map6507.5UniSTS
Cytogenetic Map6q22UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
4889848Pur25Proteinuria QTL 25140.003total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)65672856290198260Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)66304056271636266Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:814
Count of miRNA genes:242
Interacting mature miRNAs:284
Transcripts:ENSRNOT00000007509, ENSRNOT00000068293
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 42 55 39 19 39 8 10 74 35 38 11 8
Low 1 2 2 2 1 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000077578   ⟹   ENSRNOP00000074395
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl669,047,776 - 69,134,102 (-)Ensembl
Rnor_6.0 Ensembl672,376,330 - 72,462,658 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000088720   ⟹   ENSRNOP00000071600
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl669,047,776 - 69,134,102 (-)Ensembl
Rnor_6.0 Ensembl672,377,699 - 72,462,657 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000106600   ⟹   ENSRNOP00000087402
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl669,047,776 - 69,134,102 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111997   ⟹   ENSRNOP00000081686
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl669,047,776 - 69,134,102 (-)Ensembl
RefSeq Acc Id: NM_001029897   ⟹   NP_001025068
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2669,047,776 - 69,134,102 (-)NCBI
Rnor_6.0672,376,360 - 72,462,676 (-)NCBI
Rnor_5.0681,940,489 - 82,026,830 (-)NCBI
RGSC_v3.4671,708,959 - 71,795,287 (-)RGD
Celera667,923,577 - 68,009,729 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240075   ⟹   XP_006240137
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2669,047,776 - 69,134,097 (-)NCBI
Rnor_6.0672,376,360 - 72,462,671 (-)NCBI
Rnor_5.0681,940,489 - 82,026,830 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240076   ⟹   XP_006240138
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2669,047,776 - 69,134,097 (-)NCBI
Rnor_6.0672,376,360 - 72,462,671 (-)NCBI
Rnor_5.0681,940,489 - 82,026,830 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240077   ⟹   XP_006240139
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2669,047,776 - 69,134,097 (-)NCBI
Rnor_6.0672,376,360 - 72,462,671 (-)NCBI
Rnor_5.0681,940,489 - 82,026,830 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001025068   ⟸   NM_001029897
- UniProtKB: P58405 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006240139   ⟸   XM_006240077
- Peptide Label: isoform X3
- UniProtKB: E9PT82 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240137   ⟸   XM_006240075
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006240138   ⟸   XM_006240076
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000074395   ⟸   ENSRNOT00000077578
RefSeq Acc Id: ENSRNOP00000071600   ⟸   ENSRNOT00000088720
RefSeq Acc Id: ENSRNOP00000087402   ⟸   ENSRNOT00000106600
RefSeq Acc Id: ENSRNOP00000081686   ⟸   ENSRNOT00000111997
Protein Domains
Striatin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P58405-F1-model_v2 AlphaFold P58405 1-794 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694588
Promoter ID:EPDNEW_R5111
Type:initiation region
Name:Strn3_1
Description:striatin 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0672,462,654 - 72,462,714EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621827 AgrOrtholog
BioCyc Gene G2FUF-37587 BioCyc
Ensembl Genes ENSRNOG00000060335 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000071600 ENTREZGENE
  ENSRNOP00000071600.1 UniProtKB/TrEMBL
  ENSRNOP00000074395 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000081686 ENTREZGENE
  ENSRNOP00000081686.1 UniProtKB/TrEMBL
  ENSRNOP00000087402 ENTREZGENE
  ENSRNOP00000087402.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000077578 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000088720 ENTREZGENE
  ENSRNOT00000088720.2 UniProtKB/TrEMBL
  ENSRNOT00000106600 ENTREZGENE
  ENSRNOT00000106600.1 UniProtKB/TrEMBL
  ENSRNOT00000111997 ENTREZGENE
  ENSRNOT00000111997.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro G-protein_beta_WD-40_rep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Striatin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:114520 UniProtKB/Swiss-Prot
NCBI Gene 114520 ENTREZGENE
Pfam Striatin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Strn3 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
SMART WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZUH2_RAT UniProtKB/TrEMBL
  A0A8I6AGH7_RAT UniProtKB/TrEMBL
  E9PT82 ENTREZGENE, UniProtKB/TrEMBL
  P58405 ENTREZGENE
  Q1KLB7_RAT UniProtKB/TrEMBL
  STRN3_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-02 Strn3  striatin 3  Strn3  striatin, calmodulin binding protein 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Strn3  striatin, calmodulin binding protein 3  Gs2na  nuclear autoantigen  Symbol and Name updated 1299863 APPROVED
2002-08-07 Gs2na  nuclear autoantigen      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains six WD-40 repeats 708334