Rock2 Rat (-)-epigallocatechin 3-gallate multiple interactions ISO ROCK2 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ROCK2 mRNA CTD PMID:22079256 Rock2 Rat (S)-amphetamine affects expression ISO Rock2 (Mus musculus) 6480464 Dextroamphetamine affects the expression of ROCK2 mRNA CTD PMID:12558987 Rock2 Rat 1,2-dimethylhydrazine multiple interactions ISO Rock2 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ROCK2 mRNA CTD PMID:22206623 Rock2 Rat 1,3,5-trinitro-1,3,5-triazinane decreases expression EXP 6480464 cyclonite results in decreased expression of ROCK2 mRNA CTD PMID:25559034 Rock2 Rat 17beta-estradiol affects expression ISO Rock2 (Mus musculus) 6480464 Estradiol affects the expression of ROCK2 mRNA CTD PMID:15598610 Rock2 Rat 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of ROCK2 mRNA CTD PMID:32145629 Rock2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Rock2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of ROCK2 mRNA CTD PMID:21570461 Rock2 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ROCK2 mRNA CTD PMID:33387578 Rock2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of ROCK2 mRNA CTD PMID:34747641 Rock2 Rat 2,4,6-tribromophenol increases expression ISO ROCK2 (Homo sapiens) 6480464 2 more ... CTD PMID:31675489 Rock2 Rat 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of ROCK2 mRNA CTD PMID:21346803 Rock2 Rat 2-butoxyethanol increases expression ISO Rock2 (Mus musculus) 6480464 n-butoxyethanol results in increased expression of ROCK2 mRNA CTD PMID:19812364 Rock2 Rat 3,4-methylenedioxymethamphetamine increases expression ISO Rock2 (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of ROCK2 mRNA CTD PMID:19285098 Rock2 Rat 3,4-methylenedioxymethamphetamine decreases expression ISO Rock2 (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of ROCK2 mRNA CTD PMID:26251327 Rock2 Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO ROCK2 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ROCK2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of ROCK2 mRNA CTD PMID:28628672 Rock2 Rat 4,4'-diaminodiphenylmethane increases expression ISO Rock2 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of ROCK2 mRNA CTD PMID:18648102 Rock2 Rat 4,4'-sulfonyldiphenol increases methylation ISO ROCK2 (Homo sapiens) 6480464 bisphenol S results in increased methylation of ROCK2 gene CTD PMID:31601247 Rock2 Rat 4-hydroxyphenyl retinamide decreases expression ISO Rock2 (Mus musculus) 6480464 Fenretinide results in decreased expression of ROCK2 mRNA CTD PMID:28973697 Rock2 Rat aflatoxin B1 increases expression ISO ROCK2 (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of ROCK2 mRNA CTD PMID:27153756 Rock2 Rat aflatoxin B1 decreases methylation ISO ROCK2 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of ROCK2 gene CTD PMID:27153756 Rock2 Rat Aflatoxin B2 alpha decreases methylation ISO ROCK2 (Homo sapiens) 6480464 aflatoxin B2 results in decreased methylation of ROCK2 intron CTD PMID:30157460 Rock2 Rat Alkannin multiple interactions ISO ROCK2 (Homo sapiens) 6480464 alkannin inhibits the reaction [lipopolysaccharide more ... CTD PMID:30924981 Rock2 Rat Alkannin multiple interactions ISO Rock2 (Mus musculus) 6480464 alkannin inhibits the reaction [lipopolysaccharide more ... CTD PMID:30924981 Rock2 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of ROCK2 mRNA CTD PMID:16483693 Rock2 Rat antirheumatic drug increases expression ISO ROCK2 (Homo sapiens) 6480464 Antirheumatic Agents results in increased expression of ROCK2 mRNA CTD PMID:24449571 Rock2 Rat aristolochic acid A increases expression ISO ROCK2 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of ROCK2 protein CTD PMID:33212167 Rock2 Rat aristolochic acid A decreases expression ISO ROCK2 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of ROCK2 mRNA CTD PMID:33212167 Rock2 Rat arsane increases response to substance ISO ROCK2 (Homo sapiens) 6480464 ROCK2 mRNA results in increased susceptibility to Arsenic CTD PMID:17976673 Rock2 Rat arsenic atom increases response to substance ISO ROCK2 (Homo sapiens) 6480464 ROCK2 mRNA results in increased susceptibility to Arsenic CTD PMID:17976673 Rock2 Rat arsenite(3-) decreases expression ISO Rock2 (Mus musculus) 6480464 arsenite results in decreased expression of ROCK2 mRNA CTD PMID:33053406 Rock2 Rat arsenite(3-) increases expression ISO Rock2 (Mus musculus) 6480464 arsenite results in increased expression of ROCK2 mRNA and arsenite results in increased expression of ROCK2 protein CTD PMID:37442281 Rock2 Rat arsenite(3-) multiple interactions ISO ROCK2 (Homo sapiens) 6480464 arsenite inhibits the reaction [G3BP1 protein binds to ROCK2 mRNA] and arsenite inhibits the reaction [G3BP1 protein binds to ROCK2 protein] CTD PMID:32406909 Rock2 Rat benzo[a]pyrene increases expression ISO Rock2 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of ROCK2 mRNA CTD PMID:20127859 Rock2 Rat benzo[a]pyrene affects methylation ISO ROCK2 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of ROCK2 intron and Benzo(a)pyrene affects the methylation of ROCK2 promoter CTD PMID:27901495 and PMID:30157460 Rock2 Rat benzo[a]pyrene multiple interactions ISO Rock2 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ROCK2 mRNA CTD PMID:27858113 Rock2 Rat benzo[a]pyrene increases expression ISO ROCK2 (Homo sapiens) 6480464 Benzo(a)pyrene metabolite results in increased expression of ROCK2 mRNA CTD PMID:26314263 Rock2 Rat benzo[a]pyrene decreases expression ISO ROCK2 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of ROCK2 mRNA CTD PMID:20106945 and PMID:21632981 Rock2 Rat benzo[a]pyrene decreases expression ISO Rock2 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of ROCK2 mRNA CTD PMID:19770486 Rock2 Rat benzo[a]pyrene diol epoxide I decreases expression ISO ROCK2 (Homo sapiens) 6480464 7 more ... CTD PMID:19150397 and PMID:20018196 Rock2 Rat benzo[b]fluoranthene multiple interactions ISO Rock2 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ROCK2 mRNA CTD PMID:27858113 Rock2 Rat beta-lapachone decreases expression ISO ROCK2 (Homo sapiens) 6480464 beta-lapachone results in decreased expression of ROCK2 mRNA CTD PMID:38218311 Rock2 Rat bisphenol A increases expression ISO Rock2 (Mus musculus) 6480464 bisphenol A results in increased expression of ROCK2 mRNA CTD PMID:26063408 Rock2 Rat bisphenol A increases methylation ISO ROCK2 (Homo sapiens) 6480464 bisphenol A results in increased methylation of ROCK2 gene CTD PMID:31601247 Rock2 Rat bisphenol A decreases expression ISO Rock2 (Mus musculus) 6480464 bisphenol A results in decreased expression of ROCK2 mRNA CTD PMID:33221593 Rock2 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ROCK2 mRNA CTD PMID:34947998 Rock2 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ROCK2 mRNA CTD PMID:33296240 Rock2 Rat bisphenol A multiple interactions ISO ROCK2 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ROCK2 mRNA CTD PMID:28628672 Rock2 Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of ROCK2 mRNA CTD PMID:25181051 and PMID:32145629 Rock2 Rat bisphenol AF increases expression ISO ROCK2 (Homo sapiens) 6480464 bisphenol AF results in increased expression of ROCK2 protein CTD PMID:34186270 Rock2 Rat Bisphenol B increases expression ISO ROCK2 (Homo sapiens) 6480464 bisphenol B results in increased expression of ROCK2 protein CTD PMID:34186270 Rock2 Rat bisphenol F multiple interactions ISO ROCK2 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of ROCK2 mRNA CTD PMID:28628672 Rock2 Rat bisphenol F increases expression ISO ROCK2 (Homo sapiens) 6480464 bisphenol F results in increased expression of ROCK2 protein CTD PMID:34186270 Rock2 Rat BQ 123 multiple interactions EXP 6480464 [cyclo(Trp-Asp-Pro-Val-Leu) co-treated with BQ 788] inhibits the reaction [[5 and 7-dihydroxy-6-methoxy-2-phenylchromen-4-one co-treated with Lipopolysaccharides] results in increased phosphorylation of ROCK2 protein] CTD PMID:26694894 Rock2 Rat Brodifacoum increases expression EXP 6480464 bromfenacoum results in increased expression of ROCK2 protein CTD PMID:28903499 Rock2 Rat caffeine decreases phosphorylation ISO ROCK2 (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of ROCK2 protein CTD PMID:35688186 Rock2 Rat cannabidiol multiple interactions ISO ROCK2 (Homo sapiens) 6480464 [Cannabidiol co-treated with moringin] results in decreased expression of ROCK2 mRNA CTD PMID:30096889 Rock2 Rat carbamazepine affects expression ISO ROCK2 (Homo sapiens) 6480464 Carbamazepine affects the expression of ROCK2 mRNA CTD PMID:24752500 Rock2 Rat carbon nanotube multiple interactions ISO ROCK2 (Homo sapiens) 6480464 ROCK2 protein promotes the reaction [Nanotubes and Carbon results in increased secretion of IL1B protein] CTD PMID:24760326 Rock2 Rat carbon nanotube decreases expression ISO Rock2 (Mus musculus) 6480464 Nanotubes and Carbon analog results in decreased expression of ROCK2 mRNA CTD PMID:25554681 Rock2 Rat chloropicrin affects expression ISO ROCK2 (Homo sapiens) 6480464 chloropicrin affects the expression of ROCK2 mRNA CTD PMID:26352163 Rock2 Rat chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of ROCK2 protein CTD PMID:34058248 Rock2 Rat chromium(6+) decreases expression ISO ROCK2 (Homo sapiens) 6480464 chromium hexavalent ion results in decreased expression of ROCK2 mRNA CTD PMID:30690063 Rock2 Rat chromium(6+) multiple interactions ISO ROCK2 (Homo sapiens) 6480464 [zinc chromate results in increased abundance of chromium hexavalent ion] which results in increased expression of ROCK2 mRNA CTD PMID:38479592 Rock2 Rat chrysene multiple interactions ISO Rock2 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ROCK2 mRNA CTD PMID:27858113 Rock2 Rat cisplatin multiple interactions ISO ROCK2 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of ROCK2 mRNA CTD PMID:27392435 Rock2 Rat cisplatin decreases expression ISO ROCK2 (Homo sapiens) 6480464 Cisplatin results in decreased expression of ROCK2 mRNA CTD PMID:27392435 Rock2 Rat cobalt dichloride decreases expression ISO ROCK2 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of ROCK2 mRNA CTD PMID:19320972 Rock2 Rat cobalt dichloride increases expression ISO ROCK2 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of ROCK2 mRNA CTD PMID:26314263 Rock2 Rat cocaine affects expression EXP 6480464 Cocaine affects the expression of ROCK2 mRNA CTD PMID:20187946 Rock2 Rat copper atom increases expression EXP 6480464 Copper results in increased expression of ROCK2 mRNA CTD PMID:22465980 Rock2 Rat copper(0) increases expression EXP 6480464 Copper results in increased expression of ROCK2 mRNA CTD PMID:22465980 Rock2 Rat copper(II) sulfate increases expression ISO ROCK2 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of ROCK2 mRNA CTD PMID:19549813 Rock2 Rat coumestrol multiple interactions ISO ROCK2 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ROCK2 mRNA CTD PMID:19167446 Rock2 Rat crocidolite asbestos multiple interactions ISO ROCK2 (Homo sapiens) 6480464 ROCK2 protein promotes the reaction [Asbestos and Crocidolite results in increased secretion of IL1B protein] CTD PMID:24760326 Rock2 Rat crocidolite asbestos decreases expression ISO Rock2 (Mus musculus) 6480464 Asbestos and Crocidolite results in decreased expression of ROCK2 mRNA CTD PMID:29279043 Rock2 Rat DDT decreases expression EXP 6480464 DDT results in decreased expression of ROCK2 mRNA CTD PMID:30207508 Rock2 Rat decabromodiphenyl ether increases expression ISO ROCK2 (Homo sapiens) 6480464 decabromobiphenyl ether results in increased expression of ROCK2 protein CTD PMID:31675489 Rock2 Rat dexamethasone increases expression ISO ROCK2 (Homo sapiens) 6480464 Dexamethasone results in increased expression of ROCK2 mRNA CTD PMID:25047013 Rock2 Rat dexamethasone multiple interactions ISO Rock2 (Mus musculus) 6480464 Dexamethasone inhibits the reaction [lipopolysaccharide more ... CTD PMID:30924981 Rock2 Rat dexamethasone multiple interactions ISO ROCK2 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ROCK2 mRNA more ... CTD PMID:28628672 and PMID:30924981 Rock2 Rat dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of ROCK2 mRNA CTD PMID:21266533 Rock2 Rat dibutyl phthalate increases expression ISO Rock2 (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of ROCK2 mRNA CTD PMID:17361019 and PMID:21266533 Rock2 Rat diclofenac affects expression ISO ROCK2 (Homo sapiens) 6480464 Diclofenac affects the expression of ROCK2 mRNA CTD PMID:24752500 Rock2 Rat dimethylarsinic acid increases expression EXP 6480464 Cacodylic Acid results in increased expression of ROCK2 mRNA CTD PMID:16122865 Rock2 Rat dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of ROCK2 mRNA CTD PMID:26476374 Rock2 Rat dioxygen multiple interactions ISO ROCK2 (Homo sapiens) 6480464 ROCK2 protein affects the reaction [Oxygen deficiency results in increased expression of HIF1A protein] CTD PMID:30831131 Rock2 Rat dioxygen multiple interactions EXP 6480464 Quercetin inhibits the reaction [Oxygen deficiency results in increased expression of ROCK2 mRNA] CTD PMID:26476374 Rock2 Rat emodin decreases expression ISO ROCK2 (Homo sapiens) 6480464 Emodin results in decreased expression of ROCK2 mRNA CTD PMID:16045814 Rock2 Rat endosulfan decreases expression ISO ROCK2 (Homo sapiens) 6480464 Endosulfan results in decreased expression of ROCK2 mRNA CTD PMID:28108160 and PMID:30090376 Rock2 Rat Enterolactone multiple interactions ISO ROCK2 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ROCK2 mRNA CTD PMID:19167446 Rock2 Rat enzyme inhibitor multiple interactions ISO ROCK2 (Homo sapiens) 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of ROCK2 protein CTD PMID:23301498 Rock2 Rat epoxiconazole decreases expression ISO Rock2 (Mus musculus) 6480464 epoxiconazole results in decreased expression of ROCK2 mRNA CTD PMID:35436446 Rock2 Rat ethanol multiple interactions ISO Rock2 (Mus musculus) 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of ROCK2 mRNA CTD PMID:30517762 Rock2 Rat fasudil multiple interactions ISO ROCK2 (Homo sapiens) 6480464 fasudil inhibits the reaction [lipopolysaccharide more ... CTD PMID:30924981 Rock2 Rat fasudil multiple interactions ISO Rock2 (Mus musculus) 6480464 fasudil inhibits the reaction [Acetaminophen results in increased expression of ROCK2 protein] more ... CTD PMID:30924981 and PMID:34078832 Rock2 Rat fasudil decreases activity EXP 6480464 fasudil results in decreased activity of ROCK2 protein CTD PMID:10998351 Rock2 Rat folic acid decreases expression ISO Rock2 (Mus musculus) 6480464 Folic Acid results in decreased expression of ROCK2 mRNA CTD PMID:25629700 Rock2 Rat folic acid multiple interactions ISO Rock2 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ROCK2 mRNA CTD PMID:22206623 Rock2 Rat formaldehyde decreases expression ISO ROCK2 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of ROCK2 mRNA CTD PMID:23649840 Rock2 Rat FR900359 affects phosphorylation ISO ROCK2 (Homo sapiens) 6480464 FR900359 affects the phosphorylation of ROCK2 protein CTD PMID:37730182 Rock2 Rat fulvestrant increases methylation ISO ROCK2 (Homo sapiens) 6480464 Fulvestrant results in increased methylation of ROCK2 gene CTD PMID:31601247 Rock2 Rat geldanamycin increases expression ISO ROCK2 (Homo sapiens) 6480464 geldanamycin results in increased expression of ROCK2 mRNA CTD PMID:26705709 Rock2 Rat genistein decreases expression EXP 6480464 Genistein results in decreased expression of ROCK2 protein CTD PMID:24552547 Rock2 Rat glycyrrhetinate multiple interactions ISO ROCK2 (Homo sapiens) 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of ROCK2 mRNA] and 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of ROCK2 protein] CTD PMID:31325423 Rock2 Rat glycyrrhetinic acid multiple interactions ISO ROCK2 (Homo sapiens) 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of ROCK2 mRNA] and 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein co-treated with PDGFB protein] results in increased expression of ROCK2 protein] CTD PMID:31325423 Rock2 Rat guanosine 5'-[gamma-thio]triphosphate affects localization EXP 6480464 Guanosine 5'-O-(3-Thiotriphosphate) affects the localization of ROCK2 protein CTD PMID:12960549 Rock2 Rat guanosine 5'-[gamma-thio]triphosphate multiple interactions EXP 6480464 sevoflurane inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) affects the localization of ROCK2 protein] CTD PMID:12960549 Rock2 Rat hexadecanoic acid multiple interactions ISO ROCK2 (Homo sapiens) 6480464 [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ROCK2 protein and [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ROCK2 protein CTD PMID:30547786 Rock2 Rat indometacin decreases expression ISO ROCK2 (Homo sapiens) 6480464 Indomethacin results in decreased expression of ROCK2 mRNA CTD PMID:16984733 Rock2 Rat indometacin multiple interactions ISO ROCK2 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ROCK2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of ROCK2 mRNA CTD PMID:28628672 Rock2 Rat ivermectin decreases expression ISO ROCK2 (Homo sapiens) 6480464 Ivermectin results in decreased expression of ROCK2 protein CTD PMID:32959892 Rock2 Rat leflunomide increases expression ISO ROCK2 (Homo sapiens) 6480464 leflunomide results in increased expression of ROCK2 mRNA CTD PMID:28988120 Rock2 Rat lipopolysaccharide multiple interactions EXP 6480464 [5 more ... CTD PMID:26694894 Rock2 Rat methylmercury(1+) increases expression ISO ROCK2 (Homo sapiens) 6480464 methylmercury II results in increased expression of ROCK2 mRNA CTD PMID:26314263 Rock2 Rat miconazole decreases expression ISO Rock2 (Mus musculus) 6480464 Miconazole results in decreased expression of ROCK2 mRNA CTD PMID:27462272 Rock2 Rat N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide decreases activity EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of ROCK2 protein CTD PMID:10998351 Rock2 Rat ochratoxin A increases expression ISO ROCK2 (Homo sapiens) 6480464 ochratoxin A metabolite results in increased expression of ROCK2 mRNA and ochratoxin A results in increased expression of ROCK2 mRNA CTD PMID:26314263 Rock2 Rat oleic acid multiple interactions ISO ROCK2 (Homo sapiens) 6480464 [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ROCK2 protein and [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ROCK2 protein CTD PMID:30547786 Rock2 Rat oroxylin A multiple interactions EXP 6480464 [5 more ... CTD PMID:26694894 Rock2 Rat ouabain multiple interactions ISO ROCK2 (Homo sapiens) 6480464 benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [Ouabain results in increased cleavage of ROCK2 protein] CTD PMID:20661774 Rock2 Rat ouabain increases cleavage ISO ROCK2 (Homo sapiens) 6480464 Ouabain results in increased cleavage of ROCK2 protein CTD PMID:20661774 Rock2 Rat oxybenzone increases expression ISO ROCK2 (Homo sapiens) 6480464 oxybenzone results in increased expression of ROCK2 mRNA CTD PMID:36581016 Rock2 Rat paracetamol affects expression ISO Rock2 (Mus musculus) 6480464 Acetaminophen affects the expression of ROCK2 mRNA CTD PMID:17562736 Rock2 Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of ROCK2 mRNA CTD PMID:33387578 Rock2 Rat paracetamol increases expression ISO Rock2 (Mus musculus) 6480464 Acetaminophen results in increased expression of ROCK2 protein CTD PMID:34078832 Rock2 Rat paracetamol multiple interactions ISO Rock2 (Mus musculus) 6480464 fasudil inhibits the reaction [Acetaminophen results in increased expression of ROCK2 protein] CTD PMID:34078832 Rock2 Rat pentachlorophenol increases expression ISO Rock2 (Mus musculus) 6480464 Pentachlorophenol results in increased expression of ROCK2 mRNA CTD PMID:23892564 Rock2 Rat perfluorooctane-1-sulfonic acid decreases expression ISO ROCK2 (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in decreased expression of ROCK2 mRNA CTD PMID:27153767 Rock2 Rat phenethyl isothiocyanate decreases expression EXP 6480464 phenethyl isothiocyanate results in decreased expression of ROCK2 mRNA CTD PMID:17616710 Rock2 Rat phenobarbital multiple interactions ISO Rock2 (Mus musculus) 6480464 NR1I3 protein promotes the reaction [Phenobarbital results in increased expression of ROCK2 mRNA] CTD PMID:19482888 Rock2 Rat phenobarbital increases expression ISO Rock2 (Mus musculus) 6480464 Phenobarbital results in increased expression of ROCK2 mRNA CTD PMID:19482888 Rock2 Rat phenylephrine increases expression EXP 6480464 Phenylephrine results in increased expression of ROCK2 mRNA CTD PMID:18158353 Rock2 Rat potassium chromate multiple interactions ISO ROCK2 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ROCK2 mRNA CTD PMID:22079256 Rock2 Rat potassium chromate decreases expression ISO ROCK2 (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of ROCK2 mRNA CTD PMID:22079256 and PMID:22714537 Rock2 Rat quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [Oxygen deficiency results in increased expression of ROCK2 mRNA] CTD PMID:26476374 Rock2 Rat quercetin decreases expression ISO ROCK2 (Homo sapiens) 6480464 Quercetin results in decreased expression of ROCK2 mRNA CTD PMID:21632981 Rock2 Rat raloxifene decreases expression EXP 6480464 Raloxifene Hydrochloride results in decreased expression of ROCK2 mRNA CTD PMID:20970835 Rock2 Rat ramipril multiple interactions EXP 6480464 [Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased expression of ROCK2 protein] and Ramipril inhibits the reaction [Streptozocin results in increased expression of ROCK2 protein] CTD PMID:31062909 Rock2 Rat resveratrol multiple interactions ISO Rock2 (Mus musculus) 6480464 Resveratrol inhibits the reaction [titanium dioxide results in decreased expression of ROCK2 mRNA] CTD PMID:31298478 Rock2 Rat resveratrol multiple interactions ISO ROCK2 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of ROCK2 mRNA CTD PMID:23557933 Rock2 Rat resveratrol multiple interactions EXP 6480464 [Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased expression of ROCK2 protein] and Resveratrol inhibits the reaction [Streptozocin results in increased expression of ROCK2 protein] CTD PMID:31062909 Rock2 Rat Sanggenon C decreases expression EXP 6480464 sanggenone C results in decreased expression of ROCK2 protein CTD PMID:32240450 Rock2 Rat sevoflurane multiple interactions EXP 6480464 sevoflurane inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) affects the localization of ROCK2 protein] CTD PMID:12960549 Rock2 Rat sodium arsenate increases expression ISO Rock2 (Mus musculus) 6480464 sodium arsenate results in increased expression of ROCK2 mRNA CTD PMID:21795629 Rock2 Rat sodium arsenite decreases expression ISO Rock2 (Mus musculus) 6480464 sodium arsenite results in decreased expression of ROCK2 protein CTD PMID:26135927 Rock2 Rat sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of ROCK2 mRNA CTD PMID:35314868 Rock2 Rat sodium arsenite increases expression ISO ROCK2 (Homo sapiens) 6480464 sodium arsenite results in increased expression of ROCK2 mRNA CTD PMID:38568856 Rock2 Rat sodium fluoride decreases expression ISO Rock2 (Mus musculus) 6480464 Sodium Fluoride results in decreased expression of ROCK2 mRNA CTD PMID:21340527 Rock2 Rat streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of ROCK2 protein CTD PMID:31062909 Rock2 Rat streptozocin multiple interactions EXP 6480464 [Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased expression of ROCK2 protein] more ... CTD PMID:31062909 Rock2 Rat sunitinib increases expression ISO ROCK2 (Homo sapiens) 6480464 Sunitinib results in increased expression of ROCK2 mRNA CTD PMID:31533062 Rock2 Rat tetrachloromethane multiple interactions ISO Rock2 (Mus musculus) 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of ROCK2 mRNA CTD PMID:30517762 Rock2 Rat tetrachloromethane increases expression ISO Rock2 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of ROCK2 mRNA CTD PMID:31919559 Rock2 Rat tetrachloromethane multiple interactions EXP 6480464 Y 27632 inhibits the reaction [Carbon Tetrachloride results in increased expression of ROCK2 mRNA] CTD PMID:30783172 Rock2 Rat tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of ROCK2 mRNA CTD PMID:30783172 Rock2 Rat tetrahydropalmatine decreases expression ISO ROCK2 (Homo sapiens) 6480464 tetrahydropalmatine results in decreased expression of ROCK2 protein CTD PMID:20109541 Rock2 Rat tetraphene multiple interactions ISO Rock2 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ROCK2 mRNA CTD PMID:27858113 Rock2 Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of ROCK2 mRNA CTD PMID:23411599 Rock2 Rat Thrombin increases expression EXP 6480464 Thrombin results in increased expression of ROCK2 protein CTD PMID:18287881 Rock2 Rat tipifarnib increases expression EXP 6480464 tipifarnib results in increased expression of ROCK2 mRNA CTD PMID:16403772 Rock2 Rat titanium dioxide multiple interactions ISO Rock2 (Mus musculus) 6480464 Resveratrol inhibits the reaction [titanium dioxide results in decreased expression of ROCK2 mRNA] CTD PMID:31298478 Rock2 Rat titanium dioxide decreases expression ISO Rock2 (Mus musculus) 6480464 titanium dioxide results in decreased expression of ROCK2 mRNA CTD PMID:31298478 Rock2 Rat tributylstannane increases expression ISO ROCK2 (Homo sapiens) 6480464 tributyltin results in increased expression of ROCK2 mRNA CTD PMID:26314263 Rock2 Rat Tributyltin oxide increases expression ISO ROCK2 (Homo sapiens) 6480464 bis(tri-n-butyltin)oxide results in increased expression of ROCK2 mRNA CTD PMID:26314263 Rock2 Rat trichloroethene increases methylation EXP 6480464 Trichloroethylene results in increased methylation of ROCK2 gene CTD PMID:27618143 Rock2 Rat trichostatin A increases expression ISO ROCK2 (Homo sapiens) 6480464 trichostatin A results in increased expression of ROCK2 mRNA CTD PMID:24935251 and PMID:26272509 Rock2 Rat triphenyl phosphate affects expression ISO ROCK2 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of ROCK2 mRNA CTD PMID:37042841 Rock2 Rat Triptolide decreases expression EXP 6480464 triptolide results in decreased expression of ROCK2 mRNA CTD PMID:27554044 Rock2 Rat trovafloxacin decreases expression ISO Rock2 (Mus musculus) 6480464 trovafloxacin results in decreased expression of ROCK2 mRNA CTD PMID:35537566 Rock2 Rat tungsten decreases expression ISO Rock2 (Mus musculus) 6480464 Tungsten results in decreased expression of ROCK2 mRNA CTD PMID:30912803 Rock2 Rat valproic acid affects expression ISO Rock2 (Mus musculus) 6480464 Valproic Acid affects the expression of ROCK2 mRNA CTD PMID:17963808 Rock2 Rat valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of ROCK2 mRNA CTD PMID:29427782 Rock2 Rat valproic acid increases expression ISO ROCK2 (Homo sapiens) 6480464 Valproic Acid results in increased expression of ROCK2 mRNA CTD PMID:28001369 Rock2 Rat vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of ROCK2 mRNA CTD PMID:23555832 Rock2 Rat Y-27632 decreases activity EXP 6480464 Y 27632 results in decreased activity of ROCK2 protein CTD PMID:10998351 Rock2 Rat Y-27632 multiple interactions EXP 6480464 Y 27632 inhibits the reaction [Carbon Tetrachloride results in increased expression of ROCK2 mRNA] CTD PMID:30783172