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Gene: Rock2 (Rho-associated coiled-coil containing protein kinase 2) Mus musculus
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Symbol: Rock2
Name: Rho-associated coiled-coil containing protein kinase 2
Description: Exhibits protein serine/threonine kinase activity. Involved in several processes, including nervous system development; positive regulation of macromolecule metabolic process; and protein phosphorylation. Localizes to Schaffer collateral - CA1 synapse; glutamatergic synapse; and spindle pole centrosome. Is expressed in several structures, including central nervous system; genitourinary system; heart; musculature; and somite. Orthologous to human ROCK2 (Rho associated coiled-coil containing protein kinase 2); PARTICIPATES IN transforming growth factor-beta superfamily mediated signaling pathway; Wnt signaling pathway; INTERACTS WITH (S)-amphetamine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B230113H15Rik; mKIAA0619; p164 ROCK-2; Rho-associated coiled-coil forming kinage 2; rho-associated protein kinase 2; rho-associated, coiled-coil-containing protein kinase 2; rho-associated, coiled-coil-containing protein kinase II; Rho-kinase; Rock-II; Rock2m; ROKalpha
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1216,894,895 - 16,987,823 (+)EnsemblGRCm38mm10GRCm38
GRCm381216,894,978 - 16,988,274 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371216,901,784 - 16,995,080 (+)NCBIGRCm37mm9NCBIm37
MGSCv361216,920,670 - 17,003,586 (+)NCBImm8
Celera1217,218,328 - 17,311,507 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rock2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11243
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.