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Gene: ROCK2 (Rho associated coiled-coil containing protein kinase 2) Homo sapiens
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Symbol: ROCK2
Name: Rho associated coiled-coil containing protein kinase 2
Description: Exhibits Rho-dependent protein serine/threonine kinase activity. Involved in several processes, including positive regulation of macromolecule metabolic process; protein phosphorylation; and regulation of epithelial cell differentiation. Localizes to centrosome; cytoplasmic ribonucleoprotein granule; and cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: KIAA0619; p164 ROCK-2; rho kinase 2; rho-associated coiled-coil forming kinase 2; rho-associated protein kinase 2; Rho-associated, coiled-coil containing protein kinase 2; rho-associated, coiled-coil-containing protein kinase 2; rho-associated, coiled-coil-containing protein kinase II; ROCK-II
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl211,179,759 - 11,348,330 (-)EnsemblGRCh38hg38GRCh38
GRCh38211,179,759 - 11,345,437 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37211,319,894 - 11,484,711 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36211,239,229 - 11,402,162 (-)NCBINCBI36hg18NCBI36
Build 34211,272,375 - 11,435,309NCBI
Celera211,237,615 - 11,400,586 (-)NCBI
Cytogenetic Map2p25.1NCBI
HuRef211,171,519 - 11,335,102 (-)NCBIHuRef
CHM1_1211,249,401 - 11,414,986 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Genomics

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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ROCK2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731503
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-05-19
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.