Scort4 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Scort4 (Serum corticosterone level QTL 4) Rattus norvegicus

Symbol: Scort4
Name: Serum corticosterone level QTL 4
RGD ID: 9590140
Previously known as: plasma cort at basal level; plasma corticosterone at basal level
Trait: blood corticosterone amount   (VT:0005345)    
Measurement Type: plasma corticosterone level   (CMO:0001173)    
LOD Score: 14.49
P Value: 0.001
Variance: 15.4
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8644,510,974 - 89,510,974RGD_MAPPER_PIPELINE
mRatBN7.2638,783,989 - 83,783,989RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0641,679,046 - 86,679,046RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0651,267,831 - 96,267,831RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4641,096,237 - 86,096,237RGD_MAPPER_PIPELINERGSC3.4
Cross Type: intercross
Strains Crossed: F344/IcoCrlf LOU/NimrOlaHsd 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Scort4Ratlipid metabolism disorder  IAGP 8694157 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Scort4Ratincreased circulating corticosterone level  IDA 8694157 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Scort4Ratplasma corticosterone level  IDA 8694157 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Scort4Ratcontrol condition  IDA 8694157 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Scort4Ratradioimmunoassay  IDA 8694157 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Scort4RatF344/IcoCrlf  IEA 8694157 RGD 
Scort4RatLOU/NimrOlaHsd  IEA 8694157 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Scort4Ratblood corticosterone amount  IDA 8694157 RGD 


#
Reference Title
Reference Citation
1. Quantitative Trait Loci Influencing Abdominal Fat Deposition and Functional Variability of the HPA Axis in the Rat. Marissal-Arvy N, etal., Horm Metab Res. 2014 Jul 8.


1 to 20 of 417 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
7500641LOC102555927uncharacterized LOC10255592763877891638822800Rat
2321713Rpl11-ps2ribosomal protein L11, pseudogene 263892067338921200Rat
40932412LOC120093236uncharacterized LOC12009323663918573239186930Rat
7501955LOC102550954uncharacterized LOC10255095463925363339290633Rat
1307646Lpin1lipin 163930919839417034Rat
70962Ntsr2neurotensin receptor 263942429739431015Rat
1564091Greb1growth regulating estrogen receptor binding 163944052239562364Rat
631412E2f6E2F transcription factor 663959222439608685Rat
3590Rock2Rho-associated coiled-coil containing protein kinase 263967911639774033Rat
1306818Slc66a3solute carrier family 66 member 363977480139786554Rat
1582838Cimip5ciliary microtubule inner protein 563979241639797072Rat
631414Kcnf1potassium voltage-gated channel modifier subfamily F member 163996230139964979Rat
628688Pdia6protein disulfide isomerase family A, member 664006298040080223Rat
1359430Atp6v1c2ATPase H+ transporting V1 subunit C264008054540144199Rat
1359447Nol10nucleolar protein 1064014421740225353Rat
1561890Cfdp1l1craniofacial development protein 1 like 164025471740255884Rat
1597342Psme3-ps2proteasome activator subunit 3, pseudogene 264027018740271205Rat
3227Odc1ornithine decarboxylase 164032983140336444Rat
41218949Snora80bsmall nucleolar RNA, H/ACA box 80B64033114340331276Rat
41299246Trnav-aac13transfer RNA valine (anticodon AAC) 1364041593840416018Rat

1 to 20 of 417 rows
1 to 20 of 524 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
5032054AU04682410163910106339101164Ratregion
5065976BE11637315563930709539307250Ratregion
5084922AI17177513163931183239311963Ratregion
5044268RH13050519163943075439430945Ratregion
5073214RH13730615063944059139440741Ratregion
5035196BM39055917063944215639442326Ratregion
5073748RH13761512363945444939454572Ratregion
60540D6Got4423763952980639530031Ratregion
60542D6Got4620363957175439571957Ratregion
5058238BF38688016863959363139593799Ratregion
5044054RH13038320163960843039608631Ratregion
40770D6Rat13924563963395539634300Ratregion
40770D6Rat13924563963405339634300Ratregion
5089981AU04947922063965834839658568Ratregion
5089981AU04947922063965834839659559Ratregion
5089981AU04947922063965843239658568Ratregion
37662D6Rat9226963967147639671747Ratregion
36560D6Rat3417263971455039714722Ratregion
5054297RH14314326463973360039733864Ratregion
5030043AW53115421063976668839766898Ratregion
1 to 20 of 524 rows

Peak: (D6Rat50)
Rat AssemblyChrPosition (strand)Source
GRCr8667,010,889 - 67,011,060 (+)Marker Load Pipeline
mRatBN7.2661,283,904 - 61,284,075 (+)MAPPER
Rnor_6.0664,178,961 - 64,179,131NCBI
Rnor_5.0673,767,746 - 73,767,916UniSTS
RGSC_v3.4663,596,060 - 63,596,414RGD
RGSC_v3.4663,596,086 - 63,596,256UniSTS
RGSC_v3.1663,599,212 - 63,599,382RGD
Celera660,280,253 - 60,280,423UniSTS
RH 3.4 Map6441.0UniSTS
RH 3.4 Map6441.0RGD
RH 2.0 Map6617.4RGD
FHH x ACI Map652.5699RGD


1 to 10 of 58 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
8693632Alc27Alcohol consumption QTL 272.20.791drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)63432335751121479Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6141223769Rat

1 to 10 of 58 rows


Note Type Note Reference
qtl_general confidence interval 77.7-84.2 Mb 8694157
qtl_general number of animals used: 93 F2 males and 94 F2 females 8694157
qtl_general measurement method: blood samples were taken in the morning and collected on EDTA, centrifuged at 4000g for 10 min to extract the plasma, plasma corticosterone was measured with an in-house RIA kit using an anti-Cort antibody 8694157
qtl_general software package used: MultiQTL software 8694157