Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Prpf39 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of PRPF39 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Prpf39 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PRPF39 mRNA | CTD | PMID:22206623 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of PRPF39 mRNA | CTD | PMID:32145629 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of PRPF39 mRNA] | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | PRPF39 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PRPF39 mRNA | CTD | PMID:20106945 and PMID:21632981 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PRPF39 mRNA | CTD | PMID:21215274 and PMID:33387578 | 2,4,6-tribromophenol | decreases expression | ISO | PRPF39 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2-hydroxypropanoic acid | increases expression | ISO | PRPF39 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of PRPF39 mRNA | CTD | PMID:30851411 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Prpf39 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of PRPF39 mRNA | CTD | PMID:26251327 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Prpf39 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of PRPF39 mRNA | CTD | PMID:18648102 | 4-hydroxyphenyl retinamide | increases expression | ISO | Prpf39 (Mus musculus) | 6480464 | Fenretinide results in increased expression of PRPF39 mRNA | CTD | PMID:28973697 | acrolein | multiple interactions | ISO | PRPF39 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PRPF39 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PRPF39 mRNA | CTD | PMID:32699268 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of PRPF39 mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases expression | ISO | Prpf39 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of PRPF39 mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | decreases expression | ISO | PRPF39 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of PRPF39 mRNA | CTD | PMID:33167477 | alpha-pinene | multiple interactions | ISO | PRPF39 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PRPF39 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PRPF39 mRNA | CTD | PMID:32699268 | azoxystrobin | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PRPF39 mRNA | CTD | PMID:33854195 | benzo[a]pyrene | increases expression | ISO | Prpf39 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of PRPF39 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | decreases methylation | ISO | PRPF39 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of PRPF39 promoter | CTD | PMID:27901495 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PRPF39 mRNA | CTD | PMID:27571134 | bisphenol A | decreases expression | ISO | PRPF39 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of PRPF39 protein | CTD | PMID:31675489 | bisphenol A | decreases expression | ISO | Prpf39 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of PRPF39 mRNA | CTD | PMID:32156529 and PMID:33221593 | carbon nanotube | decreases expression | ISO | Prpf39 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chlorpyrifos | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PRPF39 mRNA | CTD | PMID:33854195 | crocidolite asbestos | decreases expression | ISO | Prpf39 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of PRPF39 mRNA | CTD | PMID:29279043 | cyclosporin A | increases expression | ISO | PRPF39 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PRPF39 mRNA | CTD | PMID:20106945 | cyclosporin A | decreases expression | ISO | Prpf39 (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of PRPF39 mRNA | CTD | PMID:19770486 | dicrotophos | decreases expression | ISO | PRPF39 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of PRPF39 mRNA | CTD | PMID:28302478 | diquat | decreases expression | ISO | Prpf39 (Mus musculus) | 6480464 | Diquat results in decreased expression of PRPF39 protein | CTD | PMID:36851058 | folic acid | multiple interactions | ISO | Prpf39 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PRPF39 mRNA | CTD | PMID:22206623 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of PRPF39 mRNA | CTD | PMID:33387578 | glyphosate | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PRPF39 mRNA | CTD | PMID:33854195 | glyphosate | increases expression | EXP | | 6480464 | Glyphosate results in increased expression of PRPF39 mRNA | CTD | PMID:26302742 | imidacloprid | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PRPF39 mRNA | CTD | PMID:33854195 | methylphenidate | increases expression | ISO | Prpf39 (Mus musculus) | 6480464 | Methylphenidate results in increased expression of PRPF39 mRNA | CTD | PMID:22470460 | nickel atom | affects expression | ISO | PRPF39 (Homo sapiens) | 6480464 | Nickel affects the expression of PRPF39 mRNA | CTD | PMID:14575637 | nickel atom | multiple interactions | ISO | PRPF39 (Homo sapiens) | 6480464 | trichostatin A inhibits the reaction [Nickel affects the expression of PRPF39 mRNA] | CTD | PMID:14575637 | ozone | multiple interactions | ISO | PRPF39 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PRPF39 mRNA more ... | CTD | PMID:32699268 | ozone | multiple interactions | ISO | Prpf39 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of PRPF39 mRNA | CTD | PMID:34911549 | paracetamol | affects expression | ISO | Prpf39 (Mus musculus) | 6480464 | Acetaminophen affects the expression of PRPF39 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | PRPF39 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of PRPF39 mRNA | CTD | PMID:21420995 | phenobarbital | affects expression | ISO | PRPF39 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of PRPF39 mRNA | CTD | PMID:19159669 | phenobarbital | affects expression | ISO | Prpf39 (Mus musculus) | 6480464 | Phenobarbital affects the expression of PRPF39 mRNA | CTD | PMID:23091169 | rac-lactic acid | increases expression | ISO | PRPF39 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of PRPF39 mRNA | CTD | PMID:30851411 | silicon dioxide | decreases expression | ISO | Prpf39 (Mus musculus) | 6480464 | Silicon Dioxide results in decreased expression of PRPF39 mRNA | CTD | PMID:19073995 | sodium arsenate | increases expression | ISO | Prpf39 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of PRPF39 mRNA | CTD | PMID:21795629 | sodium arsenite | affects expression | ISO | PRPF39 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of PRPF39 mRNA | CTD | PMID:29319823 | succimer | multiple interactions | ISO | Prpf39 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of PRPF39 mRNA | CTD | PMID:21641980 | sunitinib | increases expression | ISO | PRPF39 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of PRPF39 mRNA | CTD | PMID:31533062 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of PRPF39 mRNA | CTD | PMID:31150632 | tetraphene | increases expression | ISO | Prpf39 (Mus musculus) | 6480464 | benz(a)anthracene results in increased expression of PRPF39 mRNA | CTD | PMID:26377693 | thiabendazole | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PRPF39 mRNA | CTD | PMID:33854195 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of PRPF39 mRNA | CTD | PMID:34492290 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of PRPF39 mRNA | CTD | PMID:33387578 | trichostatin A | multiple interactions | ISO | PRPF39 (Homo sapiens) | 6480464 | trichostatin A inhibits the reaction [Nickel affects the expression of PRPF39 mRNA] | CTD | PMID:14575637 | tris(2-butoxyethyl) phosphate | affects expression | ISO | PRPF39 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of PRPF39 mRNA | CTD | PMID:29024780 | troglitazone | decreases expression | ISO | Prpf39 (Mus musculus) | 6480464 | troglitazone results in decreased expression of PRPF39 mRNA | CTD | PMID:28973697 | trovafloxacin | increases expression | ISO | Prpf39 (Mus musculus) | 6480464 | trovafloxacin results in increased expression of PRPF39 mRNA | CTD | PMID:35537566 | tungsten | increases expression | ISO | Prpf39 (Mus musculus) | 6480464 | Tungsten results in increased expression of PRPF39 mRNA | CTD | PMID:30912803 | valproic acid | decreases methylation | ISO | PRPF39 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of PRPF39 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | PRPF39 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PRPF39 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | PRPF39 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of PRPF39 mRNA | CTD | PMID:23179753 more ... | |