C6h14orf28 (similar to human chromosome 14 open reading frame 28) - Rat Genome Database

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Gene: C6h14orf28 (similar to human chromosome 14 open reading frame 28) Rattus norvegicus
Analyze
Symbol: C6h14orf28 (Ensembl: RGD1307621)
Name: similar to human chromosome 14 open reading frame 28 (Ensembl:hypothetical LOC314168)
RGD ID: 1307621
Description: Orthologous to human C14orf28 (chromosome 14 open reading frame 28); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hypothetical LOC314168; hypothetical protein LOC314168; LOC314168; RGD1307621; uncharacterized protein C14orf28 homolog; uncharacterized protein LOC314168
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8688,701,651 - 88,710,204 (+)NCBIGRCr8
mRatBN7.2682,965,304 - 82,973,942 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl682,965,328 - 82,972,558 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx683,325,212 - 83,332,215 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0683,624,575 - 83,631,578 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0683,066,308 - 83,073,315 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0686,651,196 - 86,659,371 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl686,651,196 - 86,659,371 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0696,145,979 - 96,155,042 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4686,256,155 - 86,263,086 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1686,262,235 - 86,266,292 (+)NCBI
Celera681,533,197 - 81,540,085 (+)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
C6h14orf28
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8688,701,651 - 88,710,204 (+)NCBIGRCr8
mRatBN7.2682,965,304 - 82,973,942 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl682,965,328 - 82,972,558 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx683,325,212 - 83,332,215 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0683,624,575 - 83,631,578 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0683,066,308 - 83,073,315 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0686,651,196 - 86,659,371 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl686,651,196 - 86,659,371 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0696,145,979 - 96,155,042 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4686,256,155 - 86,263,086 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1686,262,235 - 86,266,292 (+)NCBI
Celera681,533,197 - 81,540,085 (+)NCBICelera
Cytogenetic Map6q24NCBI
C14orf28
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381444,897,275 - 44,907,257 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1444,897,275 - 44,907,257 (+)EnsemblGRCh38hg38GRCh38
GRCh371445,366,478 - 45,376,460 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361444,436,257 - 44,446,210 (+)NCBINCBI36Build 36hg18NCBI36
Celera1425,227,762 - 25,237,715 (+)NCBICelera
Cytogenetic Map14q21.2NCBI
HuRef1425,477,418 - 25,487,371 (+)NCBIHuRef
CHM1_11445,304,736 - 45,314,689 (+)NCBICHM1_1
T2T-CHM13v2.01439,089,234 - 39,099,216 (+)NCBIT2T-CHM13v2.0
Gm527
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391264,964,685 - 64,971,365 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1264,964,680 - 64,971,366 (+)EnsemblGRCm39 Ensembl
GRCm381264,917,911 - 64,924,591 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1264,917,906 - 64,924,592 (+)EnsemblGRCm38mm10GRCm38
MGSCv371266,018,898 - 66,025,578 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361265,836,516 - 65,843,196 (+)NCBIMGSCv36mm8
Celera1266,050,413 - 66,054,197 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1227.21NCBI
CUNH14orf28
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540917,012,125 - 17,024,784 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540917,014,194 - 17,023,953 (-)NCBIChiLan1.0ChiLan1.0
C15H14orf28
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21546,070,659 - 46,080,698 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11445,287,154 - 45,297,194 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01425,514,741 - 25,524,710 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11443,843,018 - 43,852,917 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1443,843,018 - 43,852,917 (+)Ensemblpanpan1.1panPan2
C8H14orf28
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1822,366,822 - 22,378,411 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl822,369,790 - 22,375,025 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha822,184,834 - 22,196,392 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0822,525,913 - 22,537,473 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl822,526,893 - 22,535,764 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1822,188,391 - 22,199,954 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0822,254,701 - 22,266,253 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0822,590,803 - 22,602,360 (+)NCBIUU_Cfam_GSD_1.0
CUNH14orf28
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864054,323,411 - 54,333,350 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365834,355,492 - 4,363,107 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365834,355,562 - 4,365,470 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C1H14orf28
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1175,145,913 - 175,156,606 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11175,145,918 - 175,156,597 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21194,910,933 - 194,921,563 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CUNH14orf28
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12422,015,251 - 22,026,008 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2422,015,206 - 22,026,001 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666116513,820 - 524,488 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH14orf28
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473123,595,490 - 23,605,374 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in C6h14orf28
27 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:114
Count of miRNA genes:95
Interacting mature miRNAs:104
Transcripts:ENSRNOT00000034756
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)65672856290198260Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000034756   ⟹   ENSRNOP00000035231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl682,965,556 - 82,972,558 (+)Ensembl
Rnor_6.0 Ensembl686,651,196 - 86,659,371 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101605   ⟹   ENSRNOP00000096306
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl682,965,328 - 82,972,558 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107979   ⟹   ENSRNOP00000081303
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl682,968,274 - 82,972,558 (+)Ensembl
RefSeq Acc Id: NM_001108025   ⟹   NP_001101495
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8688,701,818 - 88,708,820 (+)NCBI
mRatBN7.2682,965,556 - 82,972,558 (+)NCBI
Rnor_6.0686,651,196 - 86,659,371 (+)NCBI
Rnor_5.0696,145,979 - 96,155,042 (+)NCBI
RGSC_v3.4686,256,155 - 86,263,086 (+)RGD
Celera681,533,197 - 81,540,085 (+)RGD
Sequence:
RefSeq Acc Id: XM_039112242   ⟹   XP_038968170
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8688,701,651 - 88,710,204 (+)NCBI
mRatBN7.2682,965,308 - 82,973,942 (+)NCBI
RefSeq Acc Id: XM_039112243   ⟹   XP_038968171
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8688,702,044 - 88,710,204 (+)NCBI
mRatBN7.2682,965,745 - 82,973,942 (+)NCBI
RefSeq Acc Id: XM_039112244   ⟹   XP_038968172
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8688,701,651 - 88,707,727 (+)NCBI
mRatBN7.2682,965,304 - 82,971,465 (+)NCBI
RefSeq Acc Id: XR_005505516
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8688,701,651 - 88,707,727 (+)NCBI
mRatBN7.2682,965,304 - 82,971,468 (+)NCBI
RefSeq Acc Id: NP_001101495   ⟸   NM_001108025
- UniProtKB: D4A3H4 (UniProtKB/TrEMBL),   A6HBS5 (UniProtKB/TrEMBL),   A0A8I5ZS88 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000035231   ⟸   ENSRNOT00000034756
RefSeq Acc Id: XP_038968172   ⟸   XM_039112244
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038968170   ⟸   XM_039112242
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AS79 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968171   ⟸   XM_039112243
- Peptide Label: isoform X2
- UniProtKB: D4A3H4 (UniProtKB/TrEMBL),   A6HBS5 (UniProtKB/TrEMBL),   A0A8I5ZS88 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000096306   ⟸   ENSRNOT00000101605
Ensembl Acc Id: ENSRNOP00000081303   ⟸   ENSRNOT00000107979

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A3H4-F1-model_v2 AlphaFold D4A3H4 1-309 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307621 AgrOrtholog
BioCyc Gene G2FUF-37334 BioCyc
Ensembl Genes ENSRNOG00000023230 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000034756.7 UniProtKB/TrEMBL
  ENSRNOT00000101605.1 UniProtKB/TrEMBL
  ENSRNOT00000107979.1 UniProtKB/TrEMBL
InterPro C14orf28-like UniProtKB/TrEMBL
KEGG Report rno:314168 UniProtKB/TrEMBL
NCBI Gene 314168 ENTREZGENE
PANTHER HYPOTHETICAL LOC314168 UniProtKB/TrEMBL
  PTHR35350 UniProtKB/TrEMBL
PhenoGen C6h14orf28 PhenoGen
RatGTEx ENSRNOG00000023230 RatGTEx
UniProt A0A8I5ZS88 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AS79 ENTREZGENE, UniProtKB/TrEMBL
  A6HBS5 ENTREZGENE, UniProtKB/TrEMBL
  D4A3H4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 C6h14orf28  similar to human chromosome 14 open reading frame 28  RGD1307621  hypothetical LOC314168  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1307621  hypothetical LOC314168   RGD1307621_predicted  hypothetical LOC314168 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1307621_predicted  hypothetical LOC314168 (predicted)  LOC314168_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC314168_predicted  hypothetical LOC314168 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL