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Gene: Agr2 (anterior gradient 2, protein disulphide isomerase family member) Rattus norvegicus
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Symbol: Agr2
Name: anterior gradient 2, protein disulphide isomerase family member
Description: Predicted to have dystroglycan binding activity; epidermal growth factor receptor binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including lung goblet cell differentiation; mucus secretion; and positive regulation of signal transduction. Predicted to localize to the endoplasmic reticulum and extracellular space. Used to study in situ carcinoma. Orthologous to human AGR2 (anterior gradient 2, protein disulphide isomerase family member); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: anterior gradient 2; anterior gradient 2 (Xenopus laevis) ; anterior gradient 2 homolog; anterior gradient 2 homolog (Xenopus laevis); anterior gradient homolog 2; anterior gradient homolog 2 (Xenopus laevis); anterior gradient protein 2 homolog; LOC298961
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0655,465,782 - 55,487,087 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0665,081,213 - 65,102,524 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4654,695,633 - 54,716,858 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1654,709,609 - 54,719,927 (+)NCBI
Celera651,855,174 - 51,875,917 (+)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Agr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1304606
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.