Gene: Nampt (nicotinamide phosphoribosyltransferase) Rattus norvegicus
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Symbol: Nampt
Name: nicotinamide phosphoribosyltransferase
Description: Exhibits several functions, including cytokine activity, drug binding activity, and nicotinamide phosphoribosyltransferase activity; involved in several processes, including aging, cellular response to amyloid-beta, and cellular response to ionizing radiation; localizes to the cytoplasm, nucleus, and plasma membrane; used to study middle cerebral artery infarction and transient cerebral ischemia; biomarker of kidney failure, periodontitis, and pulmonary hypertension; orthologous to human NAMPT (nicotinamide phosphoribosyltransferase); PARTICIPATES IN niacin metabolic pathway; nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; monoterpenoid biosynthetic pathway; INTERACTS WITH (S)-nicotine; 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: NAmPRTase; Pbef; Pbef1; pre-B-cell colony enhancing factor 1; pre-B-cell colony-enhancing factor; pre-B-cell colony-enhancing factor 1 homolog; visfatin
Orthologs:
Homo sapiens (human) : NAMPT (nicotinamide phosphoribosyltransferase)  HGNC  Alliance
Mus musculus (house mouse) : Nampt (nicotinamide phosphoribosyltransferase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nampt (nicotinamide phosphoribosyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : NAMPT (nicotinamide phosphoribosyltransferase)
Canis lupus familiaris (dog) : NAMPT (nicotinamide phosphoribosyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nampt (nicotinamide phosphoribosyltransferase)
Sus scrofa (pig) : NAMPT (nicotinamide phosphoribosyltransferase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0652,122,085 - 52,156,473 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0661,753,125 - 61,787,575 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4651,129,160 - 51,166,514 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1651,132,285 - 51,169,639 (+)NCBI
Celera648,619,485 - 48,654,540 (+)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Nampt
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 631365
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.