Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631365
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nampt
Name: nicotinamide phosphoribosyltransferase
Acc ID: CHEBI:16171
Term: NMN zwitterion
Definition: A nicotinamide mononucleotide that has formula C11H15N2O8P.
Chemical ID: MESH:D009537
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Namptaffects bindingEXP 6480464CTDNAMPT protein binds to Nicotinamide MononucleotidePMID:16901503
Namptmultiple interactionsISONampt (Mus musculus)6480464CTDNicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA inhibits the reaction [NAMPT protein results in increased chemical synthesis of NAD]]PMID:23834033
Namptmultiple interactionsISONAMPT (Homo sapiens)6480464CTDNicotinamide Mononucleotide affects the reaction [NAMPT protein affects the expression of CCND1 protein]; Nicotinamide Mononucleotide affects the reaction [NAMPT protein affects the expression of CTNNB1 protein]PMID:32005247
Go Back to source page   Continue to Ontology report