NAMPT (nicotinamide phosphoribosyltransferase) - Rat Genome Database

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Gene: NAMPT (nicotinamide phosphoribosyltransferase) Pan paniscus
Analyze
Symbol: NAMPT
Name: nicotinamide phosphoribosyltransferase
RGD ID: 12033393
Description: ENCODES a protein that exhibits cytokine activity (ortholog); heterocyclic compound binding (ortholog); identical protein binding (ortholog); INVOLVED IN adipose tissue development (ortholog); cellular response to amyloid-beta (ortholog); cellular response to hypoxia (ortholog); PARTICIPATES IN niacin metabolic pathway; nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; ASSOCIATED WITH allergic contact dermatitis (ortholog); carotid artery disease (ortholog); colitis (ortholog); FOUND IN cell junction (ortholog); nuclear speck (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26143,085,389 - 143,122,843 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17191,355,357 - 191,392,827 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0798,227,071 - 98,262,254 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17110,952,876 - 110,989,233 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7110,952,876 - 110,981,967 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NAMPT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26143,085,389 - 143,122,843 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17191,355,357 - 191,392,827 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0798,227,071 - 98,262,254 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17110,952,876 - 110,989,233 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7110,952,876 - 110,981,967 (-)Ensemblpanpan1.1panPan2
NAMPT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387106,248,298 - 106,285,888 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7106,248,298 - 106,285,966 (-)EnsemblGRCh38hg38GRCh38
GRCh377105,888,744 - 105,925,429 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367105,675,967 - 105,712,874 (-)NCBINCBI36Build 36hg18NCBI36
Build 347105,495,899 - 105,519,318NCBI
Celera7100,694,260 - 100,731,169 (-)NCBICelera
Cytogenetic Map7q22.3NCBI
HuRef7100,248,062 - 100,285,253 (-)NCBIHuRef
CHM1_17105,822,212 - 105,859,137 (-)NCBICHM1_1
T2T-CHM13v2.07107,563,712 - 107,602,631 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27105,249,752 - 105,286,646 (-)NCBI
Nampt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391232,870,334 - 32,903,368 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1232,869,544 - 32,903,348 (+)EnsemblGRCm39 Ensembl
GRCm381232,820,335 - 32,853,369 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1232,819,545 - 32,853,349 (+)EnsemblGRCm38mm10GRCm38
MGSCv371233,505,200 - 33,538,234 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361233,405,722 - 33,436,855 (+)NCBIMGSCv36mm8
Celera1234,264,778 - 34,297,952 (+)NCBICelera
Cytogenetic Map12A3NCBI
cM Map1213.74NCBI
Nampt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8655,152,756 - 55,189,547 (+)NCBIGRCr8
mRatBN7.2649,425,316 - 49,462,109 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl649,424,332 - 49,462,100 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx649,728,050 - 49,763,075 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0650,042,969 - 50,077,994 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0649,480,294 - 49,514,732 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0652,122,085 - 52,156,473 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl652,122,085 - 52,156,472 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0661,753,125 - 61,787,575 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4651,129,160 - 51,166,514 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1651,132,285 - 51,169,639 (+)NCBI
Celera648,619,485 - 48,654,540 (+)NCBICelera
Cytogenetic Map6q16NCBI
Nampt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541010,717,664 - 10,751,177 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541010,717,664 - 10,742,109 (-)NCBIChiLan1.0ChiLan1.0
NAMPT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11814,110,045 - 14,211,268 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1813,993,022 - 14,208,657 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1813,815,825 - 13,860,578 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01814,441,923 - 14,486,695 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1814,441,184 - 14,486,688 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11814,254,107 - 14,298,642 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01814,175,231 - 14,219,981 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01814,455,285 - 14,500,038 (+)NCBIUU_Cfam_GSD_1.0
Nampt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511856,558,385 - 56,593,898 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647917,682,201 - 17,716,661 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647917,682,070 - 17,716,713 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NAMPT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9106,119,899 - 106,294,586 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19106,119,896 - 106,162,126 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29116,889,082 - 116,932,047 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NAMPT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12175,160,748 - 75,195,781 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2175,158,596 - 75,196,025 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604228,713,073 - 28,750,454 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nampt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473923,411,488 - 23,442,359 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473923,411,478 - 23,444,590 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000059533   ⟹   ENSPPAP00000036641
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7110,952,876 - 110,981,496 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000059536   ⟹   ENSPPAP00000036644
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7110,955,697 - 110,981,967 (-)Ensembl
RefSeq Acc Id: XM_034964750   ⟹   XP_034820641
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26143,085,389 - 143,122,843 (-)NCBI
NHGRI_mPanPan17191,355,357 - 191,392,826 (-)NCBI
Mhudiblu_PPA_v0798,227,071 - 98,262,253 (-)NCBI
RefSeq Acc Id: XM_034964752   ⟹   XP_034820643
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26143,085,389 - 143,122,141 (-)NCBI
NHGRI_mPanPan17191,355,357 - 191,392,109 (-)NCBI
Mhudiblu_PPA_v0798,227,071 - 98,261,374 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034820641 (Get FASTA)   NCBI Sequence Viewer  
  XP_034820643 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000036641.1
  ENSPPAP00000036644.1
Reference Protein Sequences
RefSeq Acc Id: XP_034820641   ⟸   XM_034964750
- UniProtKB: A0A2R9C3V3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034820643   ⟸   XM_034964752
- UniProtKB: A0A2R9C3V3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000036641   ⟸   ENSPPAT00000059533
RefSeq Acc Id: ENSPPAP00000036644   ⟸   ENSPPAT00000059536
Protein Domains
Nicotinamide phosphoribosyltransferase N-terminal   Nicotinate/nicotinamide phosphoribosyltransferase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041053 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000059533.1 UniProtKB/TrEMBL
  ENSPPAT00000059536.1 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.70 UniProtKB/TrEMBL
InterPro Aldolase_TIM UniProtKB/TrEMBL
  DUF5598 UniProtKB/TrEMBL
  N/Namide_PRibTrfase UniProtKB/TrEMBL
  Nicotinamide_PRibTrfase UniProtKB/TrEMBL
  Nicotinate_pribotase-like_C UniProtKB/TrEMBL
NCBI Gene NAMPT ENTREZGENE
PANTHER NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE UniProtKB/TrEMBL
  PTHR43816 UniProtKB/TrEMBL
Pfam DUF5598 UniProtKB/TrEMBL
  NAPRTase UniProtKB/TrEMBL
PIRSF NMPRT UniProtKB/TrEMBL
Superfamily-SCOP SSF51690 UniProtKB/TrEMBL
UniProt A0A2R9C3V3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C4D2_PANPA UniProtKB/TrEMBL