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Gene: Allc (allantoicase) Rattus norvegicus

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Symbol:

Allc (Ensembl: Dcdc2c)

Name:

allantoicase (Ensembl:doublecortin domain containing 2C)

RGD ID:

621804

Description:

Predicted to enable allantoicase activity. Predicted to be involved in allantoin catabolic process. Orthologous to human ALLC (allantoicase); PARTICIPATES IN purine metabolic pathway; INTERACTS WITH ammonium chloride; bisphenol A; dibutyl phthalate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

allantoate amidinohydrolase; probable allantoicase; probable inactive allantoicase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ALLC (allantoicase)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Allc (allantoicase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Allc (allantoicase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ALLC (allantoicase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ALLC (allantoicase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Allc (allantoicase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ALLC (allantoicase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ALLC (allantoicase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Allc (allantoicase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	DCDC2C (doublecortin domain containing 2C)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	ALLC (allantoicase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Allc (allantoicase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	allc (allantoicase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	DAL2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	allc	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	50,907,575 - 50,942,665 (-)	NCBI		GRCr8
mRatBN7.2	6	45,179,181 - 45,214,275 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	45,179,187 - 45,214,223 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	45,470,284 - 45,505,330 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	45,785,148 - 45,820,202 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	45,222,018 - 45,257,066 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	47,812,989 - 47,848,068 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	47,774,060 - 47,848,075 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	56,515,114 - 56,549,982 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	46,421,144 - 46,456,709 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	46,434,446 - 46,444,647 (-)	NCBI
Celera	6	44,403,661 - 44,438,351 (-)	NCBI		Celera
Cytogenetic Map	6	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Allc	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	ISO	ALLC (Homo sapiens)	6480464	Tetrachlorodibenzodioxin results in increased expression of ALLC mRNA	CTD	PMID:21296121
Allc	Rat	aflatoxin B1	increases methylation	ISO	ALLC (Homo sapiens)	6480464	Aflatoxin B1 results in increased methylation of ALLC gene	CTD	PMID:27153756
Allc	Rat	aflatoxin B1	decreases methylation	ISO	ALLC (Homo sapiens)	6480464	Aflatoxin B1 results in decreased methylation of ALLC intron	CTD	PMID:30157460
Allc	Rat	Aflatoxin B2 alpha	increases methylation	ISO	ALLC (Homo sapiens)	6480464	aflatoxin B2 results in increased methylation of ALLC intron	CTD	PMID:30157460
Allc	Rat	ammonium chloride	affects expression	EXP		6480464	Ammonium Chloride affects the expression of ALLC mRNA	CTD	PMID:16483693
Allc	Rat	arsane	affects methylation	ISO	ALLC (Homo sapiens)	6480464	Arsenic affects the methylation of ALLC gene	CTD	PMID:25304211
Allc	Rat	arsenic atom	affects methylation	ISO	ALLC (Homo sapiens)	6480464	Arsenic affects the methylation of ALLC gene	CTD	PMID:25304211
Allc	Rat	benzo[a]pyrene	decreases methylation	ISO	ALLC (Homo sapiens)	6480464	Benzo(a)pyrene results in decreased methylation of ALLC promoter	CTD	PMID:27901495
Allc	Rat	benzo[a]pyrene	affects methylation	ISO	ALLC (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of ALLC 5' UTR	CTD	PMID:27901495
Allc	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of ALLC mRNA	CTD	PMID:25181051 and PMID:34947998
Allc	Rat	butanal	increases expression	ISO	ALLC (Homo sapiens)	6480464	butyraldehyde results in increased expression of ALLC mRNA	CTD	PMID:26079696
Allc	Rat	CGP 52608	multiple interactions	ISO	ALLC (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to ALLC gene]	CTD	PMID:28238834
Allc	Rat	cyclosporin A	increases expression	ISO	ALLC (Homo sapiens)	6480464	Cyclosporine results in increased expression of ALLC mRNA	CTD	PMID:25562108
Allc	Rat	dibutyl phthalate	increases expression	EXP		6480464	Dibutyl Phthalate results in increased expression of ALLC mRNA	CTD	PMID:24893172
Allc	Rat	sodium arsenite	affects methylation	ISO	ALLC (Homo sapiens)	6480464	sodium arsenite affects the methylation of ALLC gene	CTD	PMID:28589171
Allc	Rat	sodium arsenite	decreases expression	ISO	Allc (Mus musculus)	6480464	sodium arsenite results in decreased expression of ALLC mRNA	CTD	PMID:36209798
Allc	Rat	Theaflavin 3,3'-digallate	affects expression	ISO	ALLC (Homo sapiens)	6480464	theaflavin-3 and 3'-digallate affects the expression of ALLC mRNA	CTD	PMID:34925699
Allc	Rat	urethane	decreases expression	ISO	ALLC (Homo sapiens)	6480464	Urethane results in decreased expression of ALLC mRNA	CTD	PMID:28818685

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Allc	Rat	allantoin catabolic process	involved_in	IEA	InterPro:IPR005164 and InterPro:IPR015908	1600115	GO_REF:0000002	InterPro	GO_REF:0000002

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Allc	Rat	allantoicase activity	enables	IEA	EC:3.5.3.4	1600115	GO_REF:0000003	UniProt	GO_REF:0000003
Allc	Rat	allantoicase activity	enables	IEA	InterPro:IPR005164 and InterPro:IPR015908	1600115	GO_REF:0000002	InterPro	GO_REF:0000002

Imported Annotations - KEGG (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Allc	Rat	purine metabolic pathway		IEA		6907045		KEGG	rno:00230

BioCyc Pathways

allantoin degradation to ureidoglycolate I (urea producing)

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Genomic organization and chromosome localization of the murine and human allantoicase gene.	Vigetti D, etal., Gene 2002 May 1;289(1-2):13-7.

PMID:12477932	PMID:14745534	PMID:15489334

Allc
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	50,907,575 - 50,942,665 (-)	NCBI		GRCr8
mRatBN7.2	6	45,179,181 - 45,214,275 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	45,179,187 - 45,214,223 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	45,470,284 - 45,505,330 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	45,785,148 - 45,820,202 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	45,222,018 - 45,257,066 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	47,812,989 - 47,848,068 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	47,774,060 - 47,848,075 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	56,515,114 - 56,549,982 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	46,421,144 - 46,456,709 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	46,434,446 - 46,444,647 (-)	NCBI
Celera	6	44,403,661 - 44,438,351 (-)	NCBI		Celera
Cytogenetic Map	6	q16	NCBI

ALLC
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	3,645,819 - 3,702,671 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	3,658,200 - 3,702,671 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	3,705,790 - 3,750,261 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	3,683,661 - 3,728,136 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	3,235,579 - 3,243,627	NCBI
Celera	2	3,714,865 - 3,759,339 (+)	NCBI		Celera
Cytogenetic Map	2	p25.3	NCBI
HuRef	2	3,647,145 - 3,691,906 (+)	NCBI		HuRef
CHM1_1	2	3,635,517 - 3,679,645 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	3,668,711 - 3,725,243 (+)	NCBI		T2T-CHM13v2.0

Allc
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	28,603,754 - 28,632,527 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	28,603,754 - 28,632,522 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	28,553,755 - 28,582,528 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	28,553,755 - 28,582,523 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	29,238,620 - 29,267,348 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	29,140,023 - 29,168,751 (-)	NCBI		MGSCv36	mm8
Celera	12	30,043,562 - 30,072,354 (-)	NCBI		Celera
Cytogenetic Map	12	A2	NCBI
cM Map	12	10.97	NCBI

Allc
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955487	3,756,789 - 3,774,656 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955487	3,757,362 - 3,774,067 (-)	NCBI	ChiLan1.0	ChiLan1.0

ALLC
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	122,801,785 - 122,848,189 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	122,805,762 - 122,852,172 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	3,672,945 - 3,719,340 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	3,591,862 - 3,637,371 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	3,591,862 - 3,637,371 (+)	Ensembl	panpan1.1		panPan2

ALLC
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	2,185,371 - 2,215,256 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	2,185,432 - 2,215,248 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	2,171,942 - 2,201,365 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	2,280,188 - 2,309,631 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	2,280,249 - 2,309,623 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	2,164,986 - 2,194,416 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	2,185,876 - 2,215,277 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	2,187,906 - 2,217,359 (+)	NCBI		UU_Cfam_GSD_1.0

Allc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	47,027,742 - 47,060,727 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936532	1,798,884 - 1,815,676 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936532	1,798,884 - 1,815,666 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ALLC
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	3	131,195,876 - 131,213,935 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	140,404,710 - 140,422,955 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ALLC
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	103,944,649 - 103,989,845 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	103,944,761 - 103,975,876 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	8,305,545 - 8,349,837 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Allc
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624846	5,161,153 - 5,170,313 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Allc
251 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	35
Count of miRNA genes:	35
Interacting mature miRNAs:	35
Transcripts:	ENSRNOT00000011048
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	10894415	110548006	Rat
9590290	Uminl2	Urine mineral level QTL 2	3.96	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	6	38783989	83783989	Rat
8693632	Alc27	Alcohol consumption QTL 27	2.2	0.791	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	6	34323357	51121479	Rat
634318	Bw118	Body weight QTL 118	3.55		abdominal fat pad mass (VT:1000711)	abdominal fat pad weight (CMO:0000088)	6	33309549	57730294	Rat
10401812	Kidm54	Kidney mass QTL 54			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	14368788	59368788	Rat
634307	Bp141	Blood pressure QTL 141	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	35230417	80230417	Rat
2293839	Kiddil2	Kidney dilation QTL 2	4.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	20866422	81133036	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	15107216	107351382	Rat
9590140	Scort4	Serum corticosterone level QTL 4	14.49	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	38783989	83783989	Rat
2292589	Emca10	Estrogen-induced mammary cancer QTL 10		0.048	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	6	16536140	61536140	Rat
9590306	Scort18	Serum corticosterone level QTL 18	2.88	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	38783989	83783989	Rat
1578665	Bss16	Bone structure and strength QTL 16	4.4		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	6	11735669	72593685	Rat
2293841	Kiddil4	Kidney dilation QTL 4	4.4		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	20866422	81133036	Rat
1641898	Colcr4	Colorectal carcinoma resistance QTL4	3.71	0.0007	intestine integrity trait (VT:0010554)	well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)	6	20338777	62613667	Rat
1578668	Bmd14	Bone mineral density QTL 14	3.8		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	6	11735669	72593685	Rat
6893340	Cm77	Cardiac mass QTL 77	0.26	0.57	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	33309549	81132889	Rat
10401800	Kidm49	Kidney mass QTL 49			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	14368788	59368788	Rat
70199	Coreg1	Compensatory renal growth QTL 1	11.8		kidney mass (VT:0002707)	compensatory renal growth score (CMO:0001894)	6	35691618	57730540	Rat
2301972	Bp325	Blood pressure QTL 325	4.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	1	72227641	Rat
1300164	Rf15	Renal function QTL 15	3.12		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	5074497	54641141	Rat
1331779	Rf38	Renal function QTL 38	2.876		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	6	32074428	72227641	Rat
1354664	Slep2	Serum leptin concentration QTL 2	4.49		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	6	16536140	71636405	Rat
1300143	Rf14	Renal function QTL 14	2.92		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	34434137	77102317	Rat
1354632	Scl29	Serum cholesterol level QTL 29	3.74		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	6	35098709	71636405	Rat

BF387922

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	45,179,256 - 45,179,422 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	47,813,064 - 47,813,229	NCBI	Rnor6.0
Rnor_5.0	6	56,515,189 - 56,515,354	UniSTS	Rnor5.0
RGSC_v3.4	6	46,421,215 - 46,421,380	UniSTS	RGSC3.4
Celera	6	44,403,732 - 44,403,897	UniSTS
RH 3.4 Map	6	260.01	UniSTS
Cytogenetic Map	6	q16	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
4	3	12	85	64	63	56	3	56	2	85	18	81	5	39	7


RefSeq Transcripts	NM_001013037	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239944	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111788	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC125638	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF480062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC078971	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000010942 ⟹ ENSRNOP00000010942

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	6	47,774,060 - 47,811,853 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000011048 ⟹ ENSRNOP00000011048

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	45,179,187 - 45,214,223 (-)	Ensembl
Rnor_6.0 Ensembl	6	47,812,994 - 47,848,026 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000090017 ⟹ ENSRNOP00000072251

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	6	47,799,082 - 47,848,075 (-)	Ensembl

RefSeq Acc Id:

NM_001013037 ⟹ NP_001013055

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	50,907,579 - 50,942,614 (-)	NCBI
mRatBN7.2	6	45,179,186 - 45,214,223 (-)	NCBI
Rnor_6.0	6	47,812,993 - 47,848,026 (-)	NCBI
Rnor_5.0	6	56,515,114 - 56,549,982 (-)	NCBI
RGSC_v3.4	6	46,421,144 - 46,456,709 (-)	RGD
Celera	6	44,403,661 - 44,438,351 (-)	RGD

Sequence:

show sequence

GAAATTCAATCCTAAACACTGGGATCTGGACTCGGGTGAAGAACAGTCCAGCCCTTGGTTGCCTCACCTCCAAAGGCTTCCAGGCATGGTTTTTGAGACCTCCTCACTTCTGAAGCTTTCTGGCTGGG
CCTGCCCTTCTCAACTCTAGGAAGCATGGCTGATACTCCAAAGGAGGGAAAGCTGACCAGATTTCTGGACTTTACCCAGCTGATTGATTTGGCCTCTGAGTGCGTGGGAGGAAAGGTTTTGTTTGCAA
CAGATGACTTTTTTGGTCCTGCAGAAAATCTCATAAAGAGCAACAATCCGAGTTTTAAGGAAAATGAATACACTGAGTTTGGGAAATGGGTGGACGGATGGGAGACCAGGCGCAAAAGAATTCCAGGT
CACGACTGGTGTGTGATCCAACTGGGAATACAGGGCATTATCCGTGGTATCGATGTGGATATTTCTTACTTCTCAGGGAACTATGCTCCTCGAATGTCAATTCAAGCAGCAAACTTGAGTGAAGATAC
AGTGACAAACATTCCACCAAGAGGAGTTAAGATGGGGGCTGCAGCGACGTCTGAGGAATTTGTAGCCATTACTGAGCTGAAATCACACTCCTGGGATTACCTGGTTCCCATGTCGGAGCTTAAGCCAG
GGGACCCTGACTCCAGCCACAACTATTTTTTTGTTAATTCCCAGCAGAGATGGACTCATATAAGACTCAACATATTCCCAGATGGTGGCGTTGCACGCCTTCGAGTATACGGTACTGGACAGAGAGAC
TGGGCTGCACTGGATTCCACGGAACCTGTAGACCTGGTGGCCATTGCTTTCGGGGGTGTCTGTGTAGGATTTAGTAATGCACACTTTGGACATCCAAATAATATGATAGGTGTTGGCGATCCTAAGTC
CATAGCAGATGGTTGGGAAACAGCGAGAAGACTGGACCGACCCCCAGTGTTAGAAGGTAACGAGAATGGCTTTCTCCAGGTCCCAGGTTGTGAGTGGGCAGTGTTCCGATTGGCACATCCTGGAGTCA
TCACTCAAATTGAAATTGATACAAAGTACTTTAAAGGTAATTCTCCTGACAGCTGCAAAGTGGATGGGTGCATCCTGACCACCCTGGAAGAGGAAGACATGATCCGGCAGAAGTGGAGTCTTCCCGCC
CATAAGTGGAAGCCATTGCTTCCAGTCACCAAGCTAACTCCTAACCAAAATCACTTGTTGGACAGCCTGACCCTGGAGCTTCAGGATGTCATCACTCATGCCAGGATTACCATTGCCCCTGATGGCGG
TGTGAGCCGCCTTCGGCTCAAGGGCTTCCCCAGTTCCATATGTTTGCTGCGGCCCCTGAGGGAGAAACCCATGCTGAGATTCTCTCTTAAAGCGGGCTTCAGGGCGAATCTCTAAAGAGCTCATCCAT
TGTAGTACACACCCACTGCCTTTAGTATTCCGAACACCTGGTGGTTCCAATAAAATGATCACCCCAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006239944 ⟹ XP_006240006

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	50,907,575 - 50,942,665 (-)	NCBI
mRatBN7.2	6	45,179,181 - 45,214,275 (-)	NCBI
Rnor_6.0	6	47,812,989 - 47,848,068 (-)	NCBI
Rnor_5.0	6	56,515,114 - 56,549,982 (-)	NCBI

Sequence:

show sequence

TGCTGGTGTTCACAGTTCAAAGCCCTGGACTGTGGGGAGTGAGAAATTCAATCCTAAACACTGGGATCTGGACTCGGGTGAGATTGGAGATCTGTTTATCACATCAAGTGAAGAACAGTCCAGCCCTT
GGTTGCCTCACCTCCAAAGGCTTCCAGGCATGGTTTTTGAGACCTCCTCACTTCTGAAGCTTTCTGGCTGGGCCTGCCCTTCTCAACTCTAGGAAGCATGGCTGATACTCCAAAGGAGGGAAAGCTGA
CCAGATTTCTGGACTTTACCCAGCTGATTGATTTGGCCTCTGAGTGCGTGGGAGGAAAGGTTTTGTTTGCAACAGATGACTTTTTTGGTCCTGCAGAAAATCTCATAAAGAGCAACAATCCGAGTTTT
AAGGAAAATGAATACACTGAGTTTGGGAAATGGGTGGACGGATGGGAGACCAGGCGCAAAAGAATTCCAGGTCACGACTGGTGTGTGATCCAACTGGGAATACAGGGCATTATCCGTGGTATCGATGT
GGATATTTCTTACTTCTCAGGGAACTATGCTCCTCGAATGTCAATTCAAGCAGCAAACTTGAGTGAAGATACAGTGACAAACATTCCACCAAGAGGAGTTAAGATGGGGGCTGCAGCGACGTCTGAGG
AATTTGTAGCCATTACTGAGCTGAAATCACACTCCTGGGATTACCTGGTTCCCATGTCGGAGCTTAAGCCAGGGGACCCTGACTCCAGCCACAACTATTTTTTTGTTAATTCCCAGCAGAGATGGACT
CATATAAGACTCAACATATTCCCAGATGGTGGCGTTGCACGCCTTCGAGTATACGGTACTGGACAGAGAGACTGGGCTGCACTGGATTCCACGGAACCTGTAGACCTGGTGGCCATTGCTTTCGGGGG
TGTCTGTGTAGGATTTAGTAATGCACACTTTGGACATCCAAATAATATGATAGGTGTTGGCGATCCTAAGTCCATAGCAGATGGTTGGGAAACAGCGAGAAGACTGGACCGACCCCCAGTGTTAGAAG
GTAACGAGAATGGCTTTCTCCAGGTCCCAGGTTGTGAGTGGGCAGTGTTCCGATTGGCACATCCTGGAGTCATCACTCAAATTGAAATTGATACAAAGTACTTTAAAGGTAATTCTCCTGACAGCTGC
AAAGTGGATGGGTGCATCCTGACCACCCTGGAAGAGGAAGACATGATCCGGCAGAAGTGGAGTCTTCCCGCCCATAAGTGGAAGCCATTGCTTCCAGTCACCAAGCTAACTCCTAACCAAAATCACTT
GTTGGACAGCCTGACCCTGGAGCTTCAGGATGTCATCACTCATGCCAGGATTACCATTGCCCCTGATGGCGGTGTGAGCCGCCTTCGGCTCAAGGGCTTCCCCAGTTCCATATGTTTGCTGCGGCCCC
TGAGGGAGAAACCCATGCTGAGATTCTCTCTTAAAGCGGGCTTCAGGGCGAATCTCTAAAGAGCTCATCCATTGTAGTACACACCCACTGCCTTTAGTATTCCGAACACCTGGTGGTTCCAATAAAAT
GATCACCCCACAAA

hide sequence

RefSeq Acc Id:

XM_039111788 ⟹ XP_038967716

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	50,907,575 - 50,933,990 (-)	NCBI
mRatBN7.2	6	45,179,181 - 45,205,608 (-)	NCBI


Protein RefSeqs	NP_001013055	(Get FASTA)	NCBI Sequence Viewer
	XP_006240006	(Get FASTA)	NCBI Sequence Viewer
	XP_038967716	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH78971	(Get FASTA)	NCBI Sequence Viewer
	AAM74035	(Get FASTA)	NCBI Sequence Viewer
	EDM03212	(Get FASTA)	NCBI Sequence Viewer
	EDM03213	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000011048
	ENSRNOP00000011048.6
GenBank Protein	Q6AYP0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001013055 ⟸ NM_001013037

- UniProtKB:

Q8K470 (UniProtKB/Swiss-Prot), Q6AYP0 (UniProtKB/Swiss-Prot), A6HB08 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MADTPKEGKLTRFLDFTQLIDLASECVGGKVLFATDDFFGPAENLIKSNNPSFKENEYTEFGKWVDGWETRRKRIPGHDWCVIQLGIQGIIRGIDVDISYFSGNYAPRMSIQAANLSEDTVTNIPPRG
VKMGAAATSEEFVAITELKSHSWDYLVPMSELKPGDPDSSHNYFFVNSQQRWTHIRLNIFPDGGVARLRVYGTGQRDWAALDSTEPVDLVAIAFGGVCVGFSNAHFGHPNNMIGVGDPKSIADGWETA
RRLDRPPVLEGNENGFLQVPGCEWAVFRLAHPGVITQIEIDTKYFKGNSPDSCKVDGCILTTLEEEDMIRQKWSLPAHKWKPLLPVTKLTPNQNHLLDSLTLELQDVITHARITIAPDGGVSRLRLKG
FPSSICLLRPLREKPMLRFSLKAGFRANL

hide sequence

RefSeq Acc Id:	XP_006240006 ⟸ XM_006239944
- Peptide Label:	isoform X1
- UniProtKB:	Q8K470 (UniProtKB/Swiss-Prot), Q6AYP0 (UniProtKB/Swiss-Prot), A6HB08 (UniProtKB/TrEMBL)
- Sequence:	show sequence MADTPKEGKLTRFLDFTQLIDLASECVGGKVLFATDDFFGPAENLIKSNNPSFKENEYTEFGKW VDGWETRRKRIPGHDWCVIQLGIQGIIRGIDVDISYFSGNYAPRMSIQAANLSEDTVTNIPPRGVKMGAAATSEEFVAITELKSHSWDYLVPMSELKPGDPDSSHNYFFVNSQQRWTHIRLNIFPDGG VARLRVYGTGQRDWAALDSTEPVDLVAIAFGGVCVGFSNAHFGHPNNMIGVGDPKSIADGWETARRLDRPPVLEGNENGFLQVPGCEWAVFRLAHPGVITQIEIDTKYFKGNSPDSCKVDGCILTTLE EEDMIRQKWSLPAHKWKPLLPVTKLTPNQNHLLDSLTLELQDVITHARITIAPDGGVSRLRLKGFPSSICLLRPLREKPMLRFSLKAGFRANL hide sequence

Ensembl Acc Id:

ENSRNOP00000072251 ⟸ ENSRNOT00000090017

Ensembl Acc Id:

ENSRNOP00000010942 ⟸ ENSRNOT00000010942

Ensembl Acc Id:

ENSRNOP00000011048 ⟸ ENSRNOT00000011048

Protein Domains

Allantoicase

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6AYP0-F1-model_v2	AlphaFold	Q6AYP0	1-413	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13694531

Promoter ID:

EPDNEW_R5054

Type:

multiple initiation site

Name:

Allc_1

Description:

allantoicase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R5053

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	47,848,057 - 47,848,117	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-37969	BioCyc
BioCyc Pathway	PWY-5697 [allantoin degradation to ureidoglycolate I (urea producing)]	BioCyc
BioCyc Pathway Image	PWY-5697	BioCyc
Ensembl Genes	ENSRNOG00000008299	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000011048	ENTREZGENE
	ENSRNOT00000011048.7	UniProtKB/Swiss-Prot
Gene3D-CATH	Galactose-binding domain-like	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7111813	IMAGE-MGC_LOAD
InterPro	Allantoicase	UniProtKB/Swiss-Prot
	Allantoicase_dom	UniProtKB/Swiss-Prot
	Galactose-bd-like_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:246758	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93851	IMAGE-MGC_LOAD
NCBI Gene	246758	ENTREZGENE
PANTHER	ALLANTOICASE-RELATED	UniProtKB/Swiss-Prot
	PTHR12045	UniProtKB/Swiss-Prot
Pfam	Allantoicase	UniProtKB/Swiss-Prot
PhenoGen	Allc	PhenoGen
PIRSF	Allantoicase	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000008299	RatGTEx
Superfamily-SCOP	SSF49785	UniProtKB/Swiss-Prot
UniProt	A6HB08	ENTREZGENE, UniProtKB/TrEMBL
	ALLC_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q8K470	ENTREZGENE
UniProt Secondary	Q8K470	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-01-20	Allc	allantoicase			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Allc	allantoicase			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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BioCyc Pathways