Alc27 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Alc27 (Alcohol consumption QTL 27) Rattus norvegicus

Symbol: Alc27
Name: Alcohol consumption QTL 27
RGD ID: 8693632
Trait: drinking behavior trait   (VT:0001422)    
Measurement Type: calculated ethanol drink intake rate   (CMO:0001615)    
LOD Score: 2.2
P Value: 0.791
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8640,052,411 - 56,848,866RGD_MAPPER_PIPELINE
mRatBN7.2634,323,357 - 51,121,479RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0634,257,766 - 53,855,198RGD_MAPPER_PIPELINERnor_6.0
Rnor_5.0644,031,135 - 63,475,800RGD_MAPPER_PIPELINERnor_5.0
RGSC_v3.4635,121,447 - 53,078,918RGD_MAPPER_PIPELINERGSC_v3.4
Cross Type: Not Available
Strains Crossed: BXH/Ipcv HXB/Ipcv 



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method
scale  (IDA)

Vertebrate Trait

Rat Strain
BXH/Ipcv  (IEA)
HXB/Ipcv  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Is the Alcohol Deprivation Effect Genetically Mediated? Studies with HXB/BXH Recombinant Inbred Rat Strains. Vanderlinden LA, etal., Alcohol Clin Exp Res. 2014 Jun 24. doi: 10.1111/acer.12471.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
402377562LOC134479340uncharacterized LOC13447934064005890640067246Rat
1586345Hspa8-ps25heat shock protein family A (Hsp70) member 8, pseudogene 2564035307240355183Rat
41331744LOC120093456small nucleolar RNA SNORA1764049850340498628Rat
1586329Hat1-ps1histone acetyltransferase 1, pseudogene 164057150540573169Rat
1586335Rpl27l8ribosomal protein L27 like 864059676740597207Rat
1305961CyriaCYFIP related Rac1 interactor A64077416540883005Rat
2322296Cox7cl1cytochrome c oxidase subunit 7C like 164105596141056240Rat
402271500LOC134479279uncharacterized LOC13447927964116726641171032Rat
402076791LOC134479280uncharacterized LOC13447928064117107341193085Rat
402161456LOC134479117uncharacterized LOC13447911764121319641257589Rat
1565679Rpl27a-ps14ribosomal protein L27a, pseudogene 1464123022841230708Rat
402058830LOC134479116small ribosomal subunit protein uS8-like64126346241265492Rat
11364133Trnav-uac3transfer RNA valine (anticodon UAC) 364130914641309218Rat
41335282LOC120093419small nucleolar RNA SNORA1564132620841326334Rat
1584995MycnMYCN proto-oncogene, bHLH transcription factor64144668341452584Rat
9410455Rps16-ps1ribosomal protein S16, pseudogene 164145968441460415Rat
402012443LOC134479281uncharacterized LOC13447928164152429841533086Rat
619903Ddx1DEAD-box helicase 164172536541756236Rat
402401775LOC134479115large ribosomal subunit protein eL8-like64175153641752614Rat
1585140NbasNBAS subunit of NRZ tethering complex64177725342081895Rat
11488723LOC108351202ferritin light chain 1 pseudogene64187530041878140Rat
41070163LOC120103514uncharacterized LOC12010351464194128741944479Rat
41388044LOC120103515uncharacterized LOC12010351564211038542119973Rat
402120230LOC134479343uncharacterized LOC13447934364218853142191856Rat
1585125Morf4l1-ps9mortality factor 4 like 1, pseudogene 964231723642318041Rat
11498460LOC108351358uncharacterized LOC10835135864239873742418863Rat
1305779Lratd1LRAT domain containing 164264651542650988Rat
402204098LOC134479342uncharacterized LOC13447934264264873542910638Rat
402010547LOC134479341glyceraldehyde-3-phosphate dehydrogenase-like64268028242689136Rat
2319366Fbxw2-ps2F-box and WD repeat domain containing 2, pseudogene 264293999842943495Rat
402228051LOC134479344uncharacterized LOC13447934464296586642969016Rat
7715436LOC102555226uncharacterized LOC10255522664314538743164009Rat
11498435LOC108351205uncharacterized LOC10835120564330184043339216Rat
41258020LOC120103517uncharacterized LOC12010351764333923043425975Rat
11377656LOC108351206uncharacterized LOC10835120664337069443449351Rat
1584006Eif3b-ps1eukaryotic translation initiation factor 3, subunit B, pseudogene 164358482143587086Rat
41075541Trnaa-ggc4transfer RNA alanine (anticodon GGC) 464368020043680280Rat
1583858Tdg-ps2thymine-DNA glycosylase, pseudogene 264377939143780570Rat
7515781LOC102556604uncharacterized LOC10255660464390085244008142Rat
7557098LOC102555705uncharacterized LOC10255570564406219244076896Rat
41343564LOC120103518uncharacterized LOC12010351864424437944248193Rat
1564451Trib2tribbles pseudokinase 264427476244299139Rat
402297037LOC134479345uncharacterized LOC13447934564442241044450814Rat
7657676LOC102555864uncharacterized LOC10255586464445081944457643Rat
7500641LOC102555927uncharacterized LOC10255592764450770444557226Rat
2321713Rpl11-ps2ribosomal protein L11, pseudogene 264464945544649982Rat
40932412LOC120093236uncharacterized LOC12009323664491398144915723Rat
7501955LOC102550954uncharacterized LOC10255095464498241145022358Rat
1307646Lpin1lipin 164503911045145845Rat
70962Ntsr2neurotensin receptor 264515309545159783Rat
1564091Greb1growth regulating estrogen receptor binding 164516928945321973Rat
631412E2f6E2F transcription factor 664532099345337437Rat
3590Rock2Rho-associated coiled-coil containing protein kinase 264540782345502773Rat
1306818Slc66a3solute carrier family 66 member 364550354145515293Rat
1582838Cimip5ciliary microtubule inner protein 564552057545525810Rat
402324477LOC134479346uncharacterized LOC13447934664552574345528469Rat
631414Kcnf1potassium voltage-gated channel modifier subfamily F member 164569102845693706Rat
628688Pdia6protein disulfide isomerase family A, member 664579170445808947Rat
1359430Atp6v1c2ATPase H+ transporting V1 subunit C264580926945872914Rat
1359447Nol10nucleolar protein 1064586177345954067Rat
1561890Cfdp1l1craniofacial development protein 1 like 164598338345984583Rat
1597342Psme3-ps2proteasome activator subunit 3, pseudogene 264599889645999952Rat
3227Odc1ornithine decarboxylase 164605843946065148Rat
41218949Snora80bsmall nucleolar RNA, H/ACA box 80B64605984746059980Rat
402357388LOC134479118uncharacterized LOC13447911864608129546083829Rat
402369251LOC134479347uncharacterized LOC13447934764611296446119768Rat
41299246Trnav-aac13transfer RNA valine (anticodon AAC) 1364614463946144719Rat
41314300Ptma-ps3prothymosin alpha, pseudogene 364614970646152012Rat
40979901LOC12009323860S ribosomal protein L35-like64615234146153099Rat
708375Hpcal1hippocalcin-like 164620680946313364Rat
402032881LOC134479348uncharacterized LOC13447934864632826646330435Rat
402280070LOC134479349uncharacterized LOC13447934964634121346347360Rat
1305263Asap2ArfGAP with SH3 domain, ankyrin repeat and PH domain 264638660546549669Rat
41082662LOC120093281U6 spliceosomal RNA64645627346456379Rat
1307810Itgb1bp1integrin subunit beta 1 binding protein 164654999446564735Rat
1305767Cpsf3cleavage and polyadenylation specific factor 364656485546592776Rat
41210651LOC120093425small nucleolar RNA SNORA2164656637346566501Rat
727866Iah1isoamyl acetate hydrolyzing esterase 164659417746601394Rat
620404Adam17ADAM metallopeptidase domain 1764660158346663690Rat
41040147LOC120093315U6 spliceosomal RNA64663018246630283Rat
41197514LOC1200932755S ribosomal RNA64665156646651684Rat
3979Ywhaqtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta64666435846694875Rat
402227551LOC134479119uncharacterized LOC13447911964669789846754873Rat
402112058LOC134479120uncharacterized LOC13447912064670633246747191Rat
1596058Taf1bTATA-box binding protein associated factor, RNA polymerase I subunit B64684557146923209Rat
7731406Rbm34-ps1RNA binding motif protein 34, pseudogene 164687970046882298Rat
1305735Grhl1grainyhead-like transcription factor 164693594746986126Rat
1306646Klf11KLF transcription factor 1164701431247026152Rat
1596023Cys1cystin 164702944047046671Rat
1598310Rrm2ribonucleotide reductase regulatory subunit M264704475547075370Rat
41153839LOC120093240uncharacterized LOC12009324064710601547116923Rat
402118393LOC134479350uncharacterized LOC13447935064719008647199671Rat
1305798Mboat2membrane bound O-acyltransferase domain containing 264719975147326215Rat
619949Kidins220kinase D-interacting substrate 22064734679047435599Rat
41007282LOC120093241ubiquinol-cytochrome-c reductase complex assembly factor 3-like64745390847454374Rat
2859Id2inhibitor of DNA binding 264746916247470995Rat
402234965LOC134479282uncharacterized LOC13447928264748570847489898Rat
7526561LOC102553989uncharacterized LOC10255398964756330747583659Rat
9103871LOC103692605uncharacterized LOC10369260564763424447646175Rat
9329158Ndufa5-ps2NADH:ubiquinone oxidoreductase subunit A5, pseudogene 264765968647660026Rat
7629645LOC102554202uncharacterized LOC10255420264767428747697199Rat
402036770LOC134479351uncharacterized LOC13447935164767698447682872Rat
7536096LOC102557053uncharacterized LOC10255705364777539547848006Rat
41346264LOC120093242uncharacterized LOC12009324264799421648012026Rat
41088761LOC120093243uncharacterized LOC12009324364813444148140286Rat
1583774Phgdh-ps6phosphoglycerate dehydrogenase, pseudogene 664846456148465969Rat
1561737Rnf144aring finger protein 144A64862824148748241Rat
402063905LOC134479352uncharacterized LOC13447935264874829548755396Rat
620495Rsad2radical S-adenosyl methionine domain containing 264877498548788245Rat
1305881Cmpk2cytidine/uridine monophosphate kinase 264880215048813652Rat
11370295LOC108351213uncharacterized LOC10835121364894904448982305Rat
6501114Pgam1-ps2phosphoglycerate mutase 1, pseudogene 264919415949194892Rat
11384778LOC108351214uncharacterized LOC10835121464941162849437727Rat
2318102Silc1sciatic injury induced lincRNA upregulator of SOX1164953498049553789Rat
69351Sox11SRY-box transcription factor 1164973677349738794Rat
2324519Ube2e1-ps1ubiquitin-conjugating enzyme E2E 1, pseudogene 164985344749854088Rat
402315986LOC134479283cAMP-dependent protein kinase inhibitor gamma-like64994243349944948Rat
41387415LOC120093459small nucleolar RNA SNORA1765003098150031111Rat
9422695LOC103692606uncharacterized LOC10369260665022216050226572Rat
11407553LOC108351362uncharacterized LOC10835136265029008550296732Rat
41264357LOC120093466small nucleolar RNA SNORA1765041720750417338Rat
41262445LOC120093439small nucleolar RNA SNORA1765067694350677077Rat
41119779LOC120093290U6 spliceosomal RNA65071893450719040Rat
2322612Npm1-ps19nucleophosmin 1, pseudogene 1965080187450803067Rat
1564913Akr1b1-ps1aldo-keto reductase family 1, member B1 (aldose reductase), pseudogene 165081670150819164Rat
1559651Dcdc2cdoublecortin domain containing 2C65083240750907437Rat
621804Allcallantoicase65090757550942665Rat
41178284LOC120093293U6 spliceosomal RNA65093583850935941Rat
1309678Colec11collectin sub-family member 1165095235750984845Rat
61907Rps7ribosomal protein S765099458150999447Rat
402427254LOC134479353uncharacterized LOC13447935365100468851011275Rat
1309012Rnaseh1ribonuclease H165101124451020638Rat
727828Adi1acireductone dioxygenase 165103526751042229Rat
1566054Trappc12trafficking protein particle complex subunit 1265104987851115343Rat
1305817Eipr1EARP complex and GARP complex interacting protein 165111682751230453Rat
7747059LOC102555103uncharacterized LOC10255510365152465651563196Rat
7502861LOC102555048uncharacterized LOC10255504865156325551651059Rat
7690279LOC102554981uncharacterized LOC10255498165181968751839464Rat
402288820LOC134479356uncharacterized LOC13447935665189143851892752Rat
620550Myt1lmyelin transcription factor 1-like65189285852291830Rat
402439676LOC134479355uncharacterized LOC13447935565201294452015729Rat
402357852LOC134479354uncharacterized LOC13447935465205739952213180Rat
1560694Pxdnperoxidasin65230834752385943Rat
3900Tpothyroid peroxidase65242599852495793Rat
1311276Sntg2syntrophin, gamma 265252948152730972Rat
402231027LOC134479357uncharacterized LOC13447935765260161952608883Rat
402330140LOC134479358uncharacterized LOC13447935865276637952773858Rat
1596936Prdx1-ps5peroxiredoxin 1, pseudogene 565279630152800383Rat
41273085LOC120103519uncharacterized LOC12010351965291237452934988Rat
1359389Tmem18transmembrane protein 1865293441952941868Rat
1587117Alkal2ALK and LTK ligand 265322320453232794Rat
2020Acp1acid phosphatase 165323393753249576Rat
402345372LOC134479359uncharacterized LOC13447935965323490953238830Rat
1306440Sh3yl1SH3 and SYLF domain containing 165325003653293406Rat
1585983Hirip3-ps1HIRA interacting protein 3, pseudogene 165330331853305732Rat
40977559LOC120093438small nucleolar RNA SNORA1765335267353352805Rat
1564713Fam110cfamily with sequence similarity 110, member C65336601353372270Rat
41147221Lamb2-ps1laminin subunit beta 2, pseudogene 165342488253538994Rat
9288946LOC103692609serine palmitoyltransferase small subunit A pseudogene65353976653540276Rat
1306311Lamb1laminin subunit beta 165356284953630118Rat
735073Dlddihydrolipoamide dehydrogenase65363168653655059Rat
620623Slc26a3solute carrier family 26 member 365375141553792300Rat
1310703Cbll1Cbl proto-oncogene like 165379871253812890Rat
7499548LOC102555378uncharacterized LOC10255537865381278053843163Rat
3293Slc26a4solute carrier family 26 member 465383510253873968Rat
11492151LOC108351220uncharacterized LOC10835122065389707253901732Rat
1359431Bcap29B-cell receptor-associated protein 2965391020953950206Rat
402207861LOC134479362uncharacterized LOC13447936265395028253952907Rat
1311445Dus4ldihydrouridine synthase 4-like65395560953970050Rat
1563296Cog5component of oligomeric golgi complex 565396996754267869Rat
1310848Gpr22G protein-coupled receptor 2265403799854044994Rat
620444Hbp1HMG-box transcription factor 165425711854283373Rat
402401012LOC134479361large ribosomal subunit protein eL20-like65427040954272759Rat
3394Prkar2bprotein kinase cAMP-dependent type II regulatory subunit beta65429114354381639Rat
41021534U1l1U1 spliceosomal RNA like 165439407754394224Rat
402198615LOC134479360uncharacterized LOC13447936065448222254494742Rat
1306468Pik3cgphosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma65449424754529563Rat
41158901LOC120103521uncharacterized LOC12010352165450857754515965Rat
2320310Calm2-ps3calmodulin 2, pseudogene 365460264754605313Rat
41344174LOC120093495U4 spliceosomal RNA65468480754684934Rat
1560812Ccdc71lcoiled-coil domain containing 71-like65468747454691566Rat
2321896Nxt2-ps1nuclear transport factor 2-like export factor 2, pseudogene 165474160254742124Rat
402388858LOC134479363uncharacterized LOC13447936365502432255032127Rat
1598099Car13-ps2carbonic anhydrase 13, pseudogene 265512362155127694Rat
40944820LOC120093433small nucleolar RNA SNORA4865514097155141114Rat
631365Namptnicotinamide phosphoribosyltransferase65515275655189547Rat
41143542Metrnl-ps1meteorin-like, glial cell differentiation regulator, pseudogene 165526872755271041Rat
41201218Ccdc69-ps1coiled-coil domain containing 69, pseudogene 165527104455271593Rat
41060377Hexim2-ps1HEXIM P-TEFb complex subunit 2, pseudogene 165527208655273556Rat
7542438LOC102547473uncharacterized LOC10254747365528021155292800Rat
1359569Sypl1synaptophysin-like 165529255555311519Rat
41266620LOC120093480U6atac minor spliceosomal RNA65533263055332748Rat
1591286Cdhr3cadherin-related family member 365536921555429454Rat
402112689LOC134479364uncharacterized LOC13447936465543918455442513Rat
7719070LOC102547703uncharacterized LOC10254770365545689455487271Rat
1305730Atxn7l1ataxin 7-like 165548730955709751Rat
7563724LOC102549100uncharacterized LOC10254910065563096155646526Rat
1307943Efcab10EF-hand calcium binding domain 1065573190255738821Rat
11378331LOC108351223uncharacterized LOC10835122365574225555754534Rat
402372419LOC134479122transcription initiation factor TFIID subunit 3-like65575864655766303Rat
1307824Polr1fRNA polymerase I subunit F65578070655797935Rat
41186807LOC120093447small nucleolar RNA SNORA1765581879555818923Rat
1595482Tomm70-ps1translocase of outer mitochondrial membrane 70, pseudogene 165585232855854571Rat
6486238Rpsa-ps12ribosomal protein SA, pseudogene 1265587547355877092Rat
41134593LOC120093452small nucleolar RNA SNORA1765590639555906522Rat
402285214LOC134479365uncharacterized LOC13447936565599612356002114Rat
402269794LOC134479366uncharacterized LOC13447936665611488756125437Rat
1595449Rps20-ps6ribosomal protein S20, pseudogene 665636368856364100Rat
1311812Ferd3lFer3-like bHLH transcription factor65637277856373667Rat
41169746Pin4-ps3peptidylprolyl cis/trans isomerase, NIMA-interacting 4, pseudogene 365637534756375743Rat
621455Twist1twist family bHLH transcription factor 165640230956404303Rat
41104462LOC120093244uncharacterized LOC12009324465647247356482050Rat
1594139Dppa4-ps4developmental pluripotency-associated 4, pseudogene 465647264156473384Rat
1310748Hdac9histone deacetylase 965648947257351654Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
34184D6Mgh1116365368492153685084Ratregion
37222D6Rat8221764871328748713504Ratregion
35396D6Rat3516864016318340163351Ratregion
35447D6Rat5117564952898849529163Ratregion
37046D6Rat5211764114368141143798Ratregion
37662D6Rat9226964540022445400493Ratregion
37746D6Rat9622364428084444281067Ratregion
36534D6Rat3216564737833947378504Ratregion
36560D6Rat3417264544329445443466Ratregion
34835D6Rat2811864605060746050725Ratregion
35631D6Rat13715764885800348858160Ratregion
35911D6Rat3320664515378645153992Ratregion
39848D6Rat14315364259755942597712Ratregion
39924D6Rat14120764448027044480477Ratregion
39972D6Rat13222765654583756546064Ratregion
38220D6Rat6723564828760748287842Ratregion
38758D6Rat8314464598608545986229Ratregion
40206D6Rat15516665093089250931058Ratregion
40240D6Rat13312965460132454601453Ratregion
38930D6Rat6124964830361048303859Ratregion
39572D6Rat14011864615963046159748Ratregion
42779D6Rat22824264085795740858199Ratregion
42781D6Rat20722364729108947291312Ratregion
42782D6Rat20621465320157253201786Ratregion
40770D6Rat13924564536280745363052Ratregion
41006D6Rat13623265262526852625500Ratregion
41064D6Rat13419565343753553437730Ratregion
41608D6Rat14226864764081347641081Ratregion
41668D6Rat17023965127524151275480Ratregion
44079D6Got6423565592328555923520Ratregion
44080D6Got618365504743655047519Ratregion
44059D6Got3825464134963941349893Ratregion
44067D6Got4912064631135946311479Ratregion
60542D6Got4620364530051845300721Ratregion
60544D6Got5124664747695547477201Ratregion
62501D6Uia334965058554850585897Ratregion
67277D6Arb835764606374146064098Ratregion
1639193D6Wox247364606386946063942Ratregion
8693214rs10751130064780679747806797Ratregion
5038836RH12736035464580939045809744Ratregion
5035552MYCN72364144672741447450Ratregion
5034043RH14114521564862839948628614Ratregion
5025098AW82363313364550244145502574Ratregion
5028009M6364918765640367456403861Ratregion
5052121RH9485211564746918447469299Ratregion
5050820RH13427719364880235048802543Ratregion
5039754RH12788719164172548941725680Ratregion
5080334RH14151921164655002446550235Ratregion
8693339rs6639565665684886656848866Ratregion
8693338rs10742323464005241140052411Ratregion
5069482AU04646914864423502744235175Ratregion
5069794AU02866910265619841656198518Ratregion
5089981AU04947922064538709845387318Ratregion
5506086Myt1l58265228854452289126Ratregion
5502573RH12541077564580395445804729Ratregion
Position Markers

Flank 1: (rs107423234)
Rat AssemblyChrPosition (strand)Source
GRCr8640,052,411 - 40,052,411RGD
mRatBN7.2634,323,357 - 34,323,357RGD
Rnor_6.0634,257,766 - 34,257,766RGD
Celera633,704,443 - 33,704,443RGD
Peak: (rs107511300)
Rat AssemblyChrPosition (strand)Source
GRCr8647,806,797 - 47,806,797RGD
mRatBN7.2642,078,234 - 42,078,234RGD
Rnor_6.0644,696,315 - 44,696,315RGD
Celera641,355,021 - 41,355,021RGD
Flank 2: (rs66395656)
Rat AssemblyChrPosition (strand)Source
GRCr8656,848,866 - 56,848,866RGD
mRatBN7.2651,121,479 - 51,121,479RGD
Rnor_6.0653,855,198 - 53,855,198RGD
Celera650,287,709 - 50,287,709RGD


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6197587946975879Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)64451097489510974Rat
8693632Alc27Alcohol consumption QTL 272.20.791drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)64005241156848866Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63902865963457441Rat
4889933Bss88Bone structure and strength QTL 883.8tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)65368492198684921Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)64095756485957564Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)64515378690153786Rat
8552910Pigfal5Plasma insulin-like growth factor 1 level QTL 54.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)62265388967653889Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
5684992Bmd83Bone mineral density QTL 824.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)65368492198684921Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6323998948239989Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63118500276185002Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6197587946975879Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6197587946975879Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6144788383Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6197587946975879Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
2292616Ept15Estrogen-induced pituitary tumorigenesis QTL 154.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6197587946975879Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)64604735391047353Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6323998948239989Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6323998948239989Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)63332884178328841Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6140163351Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)63093763275937632Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)63332884178328841Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63902865986867923Rat
5684963Bss99Bone structure and strength QTL 993.1tibia area (VT:1000281)tibia area measurement (CMO:0001382)65368492198684921Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)61459947363457687Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)61608937261967788Rat
1358190Ept1Estrogen-induced pituitary tumorigenesis QTL 14.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6323998948239989Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)62228825767288257Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)64016318385163183Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general measurement method: rats were given 10% EtOH for 1 week, then for 7 weeks they were given 2-bottle choice of water and EtOH followed by 2 week period of only water (alcohol deprivation); then 2 weeks of 2-bottle choice of water and EtOH followed by second 2 weeks of alcohol deprivation then 2 weeks of 2-bottle choice of water and EtOH followed by third 2 weeks of alcohol deprivation and 1 week of 2-bottle choice of water and EtOH 8663441
qtl_general water and alcohol consumption were measured by weight 8663441
qtl_general alcohol deprivation effect (ADE) was calculated as the amount of alcohol consumed (g/kg) during 24 hrs after deprivation minus average daily amount consumed in the week before deprivation period 8663441
qtl_general this QTL correlates to week 2 pre-ADE alcohol consumption 8663441
qtl_general software used: ANOVA 8663441
qtl_general number of animals used: 70-100 days old males from HXB/BXH RI strains and the parental BN-Lx/CubPrin, SHR/OlaIpcvPrin 8663441
qtl_general spans 43.4-63.4 Mb 8663441