Dgkb (diacylglycerol kinase, beta) - Rat Genome Database

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Gene: Dgkb (diacylglycerol kinase, beta) Rattus norvegicus
Analyze
Symbol: Dgkb
Name: diacylglycerol kinase, beta
RGD ID: 2488
Description: Enables diacylglycerol kinase activity. Involved in diacylglycerol metabolic process; lipid phosphorylation; and phosphatidic acid biosynthetic process. Located in membrane. Orthologous to human DGKB (diacylglycerol kinase beta); PARTICIPATES IN glycerolipid metabolic pathway; glycerophospholipid metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 90 kDa diacylglycerol kinase; DAG kinase beta; Dagk; DGK-beta; Diacylglycerol kinase 90kDa; diacylglycerol kinase beta; diacylglycerol kinase beta 90kDa; diacylglycerol kinase beta, 90kDa; diglyceride kinase beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2654,640,948 - 55,397,210 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl654,641,614 - 55,397,043 (+)Ensembl
Rnor_6.0657,516,351 - 58,277,385 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl657,516,713 - 58,277,279 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0667,113,446 - 67,580,128 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0667,693,661 - 67,868,706 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4656,715,327 - 57,479,656 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1656,718,452 - 57,482,782 (+)NCBI
Celera653,755,433 - 54,502,520 (+)NCBICelera
RH 3.4 Map6394.3RGD
Cytogenetic Map6q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:12832407   PMID:15896305   PMID:16019106   PMID:19087171   PMID:19691842   PMID:19826069   PMID:20657643   PMID:22627129   PMID:23012479   PMID:23467923   PMID:23503970   PMID:30053369  


Genomics

Comparative Map Data
Dgkb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2654,640,948 - 55,397,210 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl654,641,614 - 55,397,043 (+)Ensembl
Rnor_6.0657,516,351 - 58,277,385 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl657,516,713 - 58,277,279 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0667,113,446 - 67,580,128 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0667,693,661 - 67,868,706 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4656,715,327 - 57,479,656 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1656,718,452 - 57,482,782 (+)NCBI
Celera653,755,433 - 54,502,520 (+)NCBICelera
RH 3.4 Map6394.3RGD
Cytogenetic Map6q21NCBI
DGKB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38714,145,049 - 14,974,858 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl714,145,049 - 14,974,777 (-)EnsemblGRCh38hg38GRCh38
GRCh37714,184,674 - 15,014,483 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36714,153,770 - 14,847,413 (-)NCBINCBI36hg18NCBI36
Build 34713,988,847 - 14,654,128NCBI
Celera714,163,789 - 14,859,377 (-)NCBI
Cytogenetic Map7p21.2NCBI
HuRef714,066,966 - 14,764,852 (-)NCBIHuRef
CHM1_1714,184,411 - 14,880,671 (-)NCBICHM1_1
T2T-CHM13v2.0714,277,079 - 15,107,587 (-)NCBI
CRA_TCAGchr7v2714,235,562 - 14,932,596 (-)NCBI
Dgkb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391237,930,169 - 38,684,238 (+)NCBIGRCm39mm39
GRCm39 Ensembl1237,867,725 - 38,684,238 (+)Ensembl
GRCm381237,880,169 - 38,634,239 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1237,817,726 - 38,634,239 (+)EnsemblGRCm38mm10GRCm38
MGSCv371238,607,292 - 39,359,997 (+)NCBIGRCm37mm9NCBIm37
MGSCv361238,390,971 - 39,143,797 (+)NCBImm8
Celera1239,316,859 - 40,057,925 (+)NCBICelera
Cytogenetic Map12A3NCBI
Dgkb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541017,676,930 - 18,243,869 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541017,677,375 - 18,304,409 (-)NCBIChiLan1.0ChiLan1.0
DGKB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1714,142,951 - 14,896,676 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl714,165,933 - 14,969,825 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0714,803,023 - 15,638,280 (-)NCBIMhudiblu_PPA_v0panPan3
DGKB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11428,916,630 - 29,609,138 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1428,918,351 - 29,537,303 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1428,434,629 - 29,133,432 (-)NCBI
ROS_Cfam_1.01428,827,965 - 29,521,435 (-)NCBI
ROS_Cfam_1.0 Ensembl1428,826,426 - 29,521,331 (-)Ensembl
UMICH_Zoey_3.11428,918,649 - 29,617,633 (-)NCBI
UNSW_CanFamBas_1.01428,647,672 - 29,348,080 (-)NCBI
UU_Cfam_GSD_1.01428,958,514 - 29,660,097 (-)NCBI
Dgkb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511873,288,180 - 74,005,408 (-)NCBI
SpeTri2.0NW_004936546964,387 - 1,615,928 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DGKB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl983,569,920 - 84,510,087 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1983,571,927 - 84,358,712 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2992,175,666 - 92,485,017 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DGKB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12143,176,715 - 43,929,833 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2143,176,989 - 43,746,258 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604260,567,411 - 61,318,935 (-)NCBIVero_WHO_p1.0
Dgkb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473915,186,115 - 15,821,907 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462473915,185,294 - 15,821,293 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D6Rat26  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2654,641,001 - 54,641,141 (+)MAPPERmRatBN7.2
Rnor_6.0657,516,400 - 57,516,539NCBIRnor6.0
Rnor_5.0667,112,834 - 67,112,973UniSTSRnor5.0
RGSC_v3.4656,714,714 - 56,714,969RGDRGSC3.4
RGSC_v3.4656,714,715 - 56,714,854UniSTSRGSC3.4
RGSC_v3.1656,717,841 - 56,717,980RGD
Celera653,754,821 - 53,754,960UniSTS
RH 3.4 Map6395.5RGD
RH 3.4 Map6395.5UniSTS
RH 2.0 Map6579.9RGD
SHRSP x BN Map640.9199RGD
Cytogenetic Map6q21UniSTS
D6Got70  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2655,224,992 - 55,225,108 (+)MAPPERmRatBN7.2
Rnor_6.0658,104,802 - 58,104,917NCBIRnor6.0
Rnor_5.0667,696,162 - 67,696,277UniSTSRnor5.0
RGSC_v3.4657,302,954 - 57,303,070RGDRGSC3.4
RGSC_v3.4657,302,955 - 57,303,070UniSTSRGSC3.4
RGSC_v3.1657,306,081 - 57,306,196RGD
Celera654,332,731 - 54,332,846UniSTS
RH 3.4 Map6391.1UniSTS
RH 3.4 Map6391.1RGD
RH 2.0 Map6569.1RGD
Cytogenetic Map6q21UniSTS
D6Arb11  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2654,856,132 - 54,856,244 (+)MAPPERmRatBN7.2
Rnor_6.0657,732,401 - 57,732,512NCBIRnor6.0
Rnor_5.0667,327,923 - 67,328,034UniSTSRnor5.0
RGSC_v3.4656,930,193 - 56,930,305RGDRGSC3.4
RGSC_v3.4656,930,194 - 56,930,305UniSTSRGSC3.4
RGSC_v3.1656,933,319 - 56,933,431RGD
Celera653,969,571 - 53,969,682UniSTS
Cytogenetic Map6q21UniSTS
BF400076  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2654,994,939 - 54,995,174 (+)MAPPERmRatBN7.2
Rnor_6.0657,870,846 - 57,871,080NCBIRnor6.0
Rnor_5.0667,465,896 - 67,466,130UniSTSRnor5.0
RGSC_v3.4657,070,530 - 57,070,764UniSTSRGSC3.4
Celera654,108,428 - 54,108,662UniSTS
RH 3.4 Map6394.5UniSTS
Cytogenetic Map6q21UniSTS
RH127545  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2655,396,852 - 55,397,058 (+)MAPPERmRatBN7.2
Rnor_6.0658,277,028 - 58,277,233NCBIRnor6.0
Rnor_5.0667,868,518 - 67,868,723UniSTSRnor5.0
RGSC_v3.4657,479,468 - 57,479,673UniSTSRGSC3.4
Celera654,502,332 - 54,502,537UniSTS
RH 3.4 Map6394.8UniSTS
Cytogenetic Map6q21UniSTS
RH144556  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2655,394,730 - 55,394,897 (+)MAPPERmRatBN7.2
Rnor_6.0658,274,906 - 58,275,072NCBIRnor6.0
Rnor_5.0667,866,396 - 67,866,562UniSTSRnor5.0
RGSC_v3.4657,477,346 - 57,477,512UniSTSRGSC3.4
Celera654,500,210 - 54,500,376UniSTS
RH 3.4 Map6386.5UniSTS
Cytogenetic Map6q21UniSTS
BF386108  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2655,014,897 - 55,015,060 (+)MAPPERmRatBN7.2
Rnor_6.0657,891,687 - 57,891,849NCBIRnor6.0
Rnor_5.0667,487,047 - 67,487,209UniSTSRnor5.0
RGSC_v3.4657,090,486 - 57,090,648UniSTSRGSC3.4
Celera654,128,840 - 54,129,002UniSTS
RH 3.4 Map6394.5UniSTS
Cytogenetic Map6q21UniSTS
BF386309  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2654,932,902 - 54,933,055 (+)MAPPERmRatBN7.2
Rnor_6.0657,808,787 - 57,808,939NCBIRnor6.0
Rnor_5.0667,403,967 - 67,404,119UniSTSRnor5.0
RGSC_v3.4657,006,994 - 57,007,146UniSTSRGSC3.4
Celera654,046,210 - 54,046,362UniSTS
RH 3.4 Map6395.0UniSTS
Cytogenetic Map6q21UniSTS
RH94439  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2655,395,182 - 55,395,382 (+)MAPPERmRatBN7.2
Rnor_6.0658,275,358 - 58,275,557NCBIRnor6.0
Rnor_5.0667,866,848 - 67,867,047UniSTSRnor5.0
RGSC_v3.4657,477,798 - 57,477,997UniSTSRGSC3.4
Celera654,500,662 - 54,500,861UniSTS
RH 3.4 Map6394.3UniSTS
Cytogenetic Map6q21UniSTS
RH135215  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2654,868,283 - 54,868,464 (+)MAPPERmRatBN7.2
Rnor_6.0657,744,550 - 57,744,730NCBIRnor6.0
Rnor_5.0667,340,072 - 67,340,252UniSTSRnor5.0
RGSC_v3.4656,942,343 - 56,942,523UniSTSRGSC3.4
Celera653,981,653 - 53,981,833UniSTS
RH 3.4 Map6385.4UniSTS
Cytogenetic Map6q21UniSTS
AU049028  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2655,012,819 - 55,013,036 (+)MAPPERmRatBN7.2
Rnor_6.0657,889,315 - 57,889,531NCBIRnor6.0
Rnor_5.0667,484,675 - 67,484,891UniSTSRnor5.0
RGSC_v3.4657,088,409 - 57,088,625UniSTSRGSC3.4
Celera654,126,763 - 54,126,979UniSTS
Cytogenetic Map6q21UniSTS
S0226  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2655,349,322 - 55,349,902 (+)MAPPERmRatBN7.2
Rnor_6.0658,229,234 - 58,229,814NCBIRnor6.0
Rnor_5.0667,820,724 - 67,821,304UniSTSRnor5.0
RGSC_v3.4657,431,934 - 57,432,513UniSTSRGSC3.4
RGSC_v3.41261,970,823 - 261,971,685UniSTSRGSC3.4
Celera654,454,803 - 54,455,382UniSTS
Celera1250,430,238 - 250,431,100UniSTS
Cytogenetic Map6q21UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)62033877762613667Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63330954957730294Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)63569161857730540Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:441
Count of miRNA genes:238
Interacting mature miRNAs:313
Transcripts:ENSRNOT00000063874
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 29 1
Low 2 32 16 16 8 8 37 25 24 11 8
Below cutoff 1 9 16 16 3 16 3 8 9 13

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000063874   ⟹   ENSRNOP00000058842
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl654,641,614 - 55,397,043 (+)Ensembl
Rnor_6.0 Ensembl657,516,713 - 58,277,279 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000111621   ⟹   ENSRNOP00000082015
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl654,641,614 - 55,397,043 (+)Ensembl
RefSeq Acc Id: NM_019304   ⟹   NP_062177
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2654,641,380 - 55,397,210 (+)NCBI
Rnor_6.0657,517,012 - 58,277,216 (+)NCBI
Rnor_5.0667,113,446 - 67,580,128 (+)NCBI
Rnor_5.0667,693,661 - 67,868,706 (+)NCBI
RGSC_v3.4656,715,327 - 57,479,656 (+)RGD
Celera653,755,433 - 54,502,520 (+)RGD
Sequence:
RefSeq Acc Id: XM_008764649   ⟹   XP_008762871
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2654,641,591 - 55,393,530 (+)NCBI
Rnor_6.0657,517,038 - 58,277,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594328   ⟹   XP_017449817
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2654,640,948 - 55,393,530 (+)NCBI
Rnor_6.0657,516,351 - 58,277,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594329   ⟹   XP_017449818
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2654,641,591 - 55,393,530 (+)NCBI
Rnor_6.0657,517,038 - 58,277,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594330   ⟹   XP_017449819
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2654,640,950 - 55,393,530 (+)NCBI
Rnor_6.0657,516,352 - 58,277,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039112775   ⟹   XP_038968703
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2654,752,019 - 55,397,210 (+)NCBI
RefSeq Acc Id: XM_039112776   ⟹   XP_038968704
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2654,752,019 - 55,393,530 (+)NCBI
RefSeq Acc Id: XM_039112777   ⟹   XP_038968705
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2654,752,019 - 55,393,530 (+)NCBI
RefSeq Acc Id: XM_039112778   ⟹   XP_038968706
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2654,752,019 - 55,393,530 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_062177   ⟸   NM_019304
- Sequence:
RefSeq Acc Id: XP_008762871   ⟸   XM_008764649
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017449817   ⟸   XM_017594328
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017449819   ⟸   XM_017594330
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017449818   ⟸   XM_017594329
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000058842   ⟸   ENSRNOT00000063874
RefSeq Acc Id: XP_038968703   ⟸   XM_039112775
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038968705   ⟸   XM_039112777
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038968704   ⟸   XM_039112776
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038968706   ⟸   XM_039112778
- Peptide Label: isoform X5
RefSeq Acc Id: ENSRNOP00000082015   ⟸   ENSRNOT00000111621
Protein Domains
DAGKc   EF-hand   Phorbol-ester/DAG-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P49621-F1-model_v2 AlphaFold P49621 1-801 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2488 AgrOrtholog
BioCyc Gene G2FUF-37770 BioCyc
Ensembl Genes ENSRNOG00000030771 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000058842 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000082015 ENTREZGENE
Ensembl Transcript ENSRNOT00000063874 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000111621 ENTREZGENE
Gene3D-CATH 1.10.238.110 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.10330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ATP-NAD_kinase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAG_kinase_typeI_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DGK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DGK_typeI_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Diacylglycerol_kin_accessory UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Diacylglycerol_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD/diacylglycerol_kinase_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:54248 UniProtKB/Swiss-Prot
NCBI Gene 54248 ENTREZGENE
PANTHER PTHR11255 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAG_kinase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAGK_acc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAGK_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dgkb PhenoGen
PROSITE DAGK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_HAND_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DAGKa UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAGKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EFh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00109 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF111331 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC231297
UniProt DGKB_RAT UniProtKB/Swiss-Prot
  F1LP01_RAT UniProtKB/TrEMBL
  P49621 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-11-06 Dgkb  diacylglycerol kinase, beta   Dagk  Diacylglycerol kinase 90kDa  Symbol and Name updated 625702 APPROVED
2002-06-10 Dagk  Diacylglycerol kinase 90kDa      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization protein localized to membrane fractions 728585
gene_domains protein contains an EF-hand motif, a cysteine-rich zinc-finger like sequence, and a putative ATP-binding site 728585
gene_expression mRNA expressed specifically in neuronal populations, including caudate-putamen, accumbens nucleus and the olfactory tubercle 728585
gene_protein 90 kDA protein is made up of 801 amino acids 728585