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Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
 Gene Annotator (Annotation Distribution) unavailable |
 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
 Gviewer (Genome Viewer) unavailable |
 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
 OLGA (Gene List Generator) unavailable |
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Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Imported Annotations - CTD | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| atrial fibrillation | ISO | RGD:731815 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:29892015, PMID:30061737 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene-Chemical Interaction AnnotationsGene Ontology AnnotationsMolecular Pathway AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Pathway AnnotationsReferences - curated| 1. | Caricasole A, etal., J Biol Chem. 2002 Feb 15;277(7):4790-6. Epub 2001 Nov 21. |
| 2. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 3. | Goto K and Kondo H, Proc Natl Acad Sci U S A 1993 Aug 15;90(16):7598-602. |
| 4. | KEGG |
| 5. | Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7 |
| 6. | MGD data from the GO Consortium |
| 7. | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 8. | Pipeline to import KEGG annotations from KEGG into RGD |
| 9. | RGD automated data pipeline |
| 10. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 11. | RGD automated import pipeline for gene-chemical interactions |
| 12. | Sato M, etal., Pharmacology. 2013;92(1-2):99-107. doi: 10.1159/000351849. Epub 2013 Aug 16. |
| 13. | Tentative Sequence Data IDs. TIGR Gene Index, Rat Data |
References - uncurated| PubMed | 12832407 15896305 16019106 19087171 19691842 19826069 20657643 22627129 23012479 23467923 23503970 |
Comparative Map Data| Dgkb (Rattus norvegicus - Norway rat) |
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| DGKB (Homo sapiens - human) |
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| Dgkb (Mus musculus - house mouse) |
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| Dgkb (Chinchilla lanigera - long-tailed chinchilla) |
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| DGKB (Pan paniscus - bonobo/pygmy chimpanzee) |
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| DGKB (Canis lupus familiaris - dog) |
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| Dgkb (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| DGKB (Sus scrofa - pig) |
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| DGKB (Chlorocebus sabaeus - African green monkey) |
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| Dgkb (Heterocephalus glaber - naked mole-rat) |
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Position Markers| D6Rat26 |
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| D6Got70 |
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| D6Arb11 |
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| BF400076 |
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| RH127545 |
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| RH144556 |
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| BF386108 |
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| BF386309 |
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| RH94439 |
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| RH135215 |
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| AU049028 |
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| S0226 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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RNA-SEQ Expression| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | 29 | 1 | |||||||||||
| Low | 2 | 32 | 16 | 16 | 8 | 8 | 37 | 25 | 24 | 11 | 8 | ||
| Below cutoff | 1 | 9 | 16 | 16 | 3 | 16 | 3 | 8 | 9 | 13 |
Nucleotide Sequences| RefSeq Transcripts | NM_019304 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_008764649 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017594328 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017594329 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017594330 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017594331 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017594332 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07063961 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AABR07063962 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07063963 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07063964 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07063965 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07063966 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07063967 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07063968 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07063969 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07063970 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043541 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043542 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043543 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043544 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043545 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043546 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043547 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043548 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043549 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043550 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043551 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043552 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043553 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043554 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043555 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043556 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043557 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043558 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043559 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01043560 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| D16100 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | ENSRNOT00000063874 ⟹ ENSRNOP00000058842 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_019304 ⟹ NP_062177 | ||||||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
GGAAAGGATCCTGAGAGGCGGCTGGTCCCAGTTCCTCTCCGGAAAAGCTGTCGCTCTCGCTTCAhide sequence |
| RefSeq Acc Id: | XM_008764649 ⟹ XP_008762871 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
CCCAGTTCCTCTCCGGAAAAGCTGTCGCTCTCGCTTCAGAGATGCGCCTAGCCTTCGCCTGCAThide sequence |
| RefSeq Acc Id: | XM_017594328 ⟹ XP_017449817 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
CAAGGGCTATAGTAGCAAAAGCAGCCTCAGCAGCCAGGCAGGGCTGTAGCTTGCAGCCAAGCAGhide sequence |
| RefSeq Acc Id: | XM_017594329 ⟹ XP_017449818 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
CCCAGTTCCTCTCCGGAAAAGCTGTCGCTCTCGCTTCAGAGATGCGCCTAGCCTTCGCCTGCAThide sequence |
| RefSeq Acc Id: | XM_017594330 ⟹ XP_017449819 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
AAGGGCTATAGTAGCAAAAGCAGCCTCAGCAGCCAGGCAGGGCTGTAGCTTGCAGCCAAGCAGAhide sequence |
| RefSeq Acc Id: | XM_017594331 ⟹ XP_017449820 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
CCCAGTTCCTCTCCGGAAAAGCTGTCGCTCTCGCTTCAGAGATGCGCCTAGCCTTCGCCTGCAThide sequence |
| RefSeq Acc Id: | XM_017594332 ⟹ XP_017449821 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
CCCAGTTCCTCTCCGGAAAAGCTGTCGCTCTCGCTTCAGAGATGCGCCTAGCCTTCGCCTGCAThide sequence |
Protein Sequences| Protein RefSeqs | NP_062177 | (Get FASTA) | NCBI Sequence Viewer |
| XP_008762871 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017449817 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017449818 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017449819 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017449820 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017449821 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | BAA03675 | (Get FASTA) | NCBI Sequence Viewer |
| P49621 | (Get FASTA) | NCBI Sequence Viewer |
| RefSeq Acc Id: | NP_062177 ⟸ NM_019304 |
| - UniProtKB: | P49621 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MTNQEKWAHLSPSEFSQLQKYAEYSTKKLKDVLEEFHGNGVLAKYNPEGKQDILNQTIDFEGFKhide sequence |
| RefSeq Acc Id: | XP_008762871 ⟸ XM_008764649 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MTNQEKWAHLSPSEFSQLQKYAEYSTKKLKDVLEEFHGNGVLAKYNPEGKQDILNQTIDFEGFKhide sequence |
| RefSeq Acc Id: | XP_017449817 ⟸ XM_017594328 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MTNQEKWAHLSPSEFSQLQKYAEYSTKKLKDVLEEFHGNGVLAKYNPEGKQDILNQTIDFEGFKhide sequence |
| RefSeq Acc Id: | XP_017449819 ⟸ XM_017594330 |
| - Peptide Label: | isoform X2 |
| - Sequence: |
MTNQEKWAHLSPSEFSQLQKYAEYSTKKLKDVLEEFHGNGVLAKYNPEGTIDFEGFKLFMKTFLhide sequence |
| RefSeq Acc Id: | XP_017449821 ⟸ XM_017594332 |
| - Peptide Label: | isoform X4 |
| - Sequence: |
MTNQEKWAHLSPSEFSQLQKYAEYSTKKLKDVLEEFHGNGVLAKYNPEGKQDILNQTIDFEGFKhide sequence |
| RefSeq Acc Id: | XP_017449818 ⟸ XM_017594329 |
| - Peptide Label: | isoform X2 |
| - Sequence: |
MTNQEKWAHLSPSEFSQLQKYAEYSTKKLKDVLEEFHGNGVLAKYNPEGTIDFEGFKLFMKTFLhide sequence |
| RefSeq Acc Id: | XP_017449820 ⟸ XM_017594331 |
| - Peptide Label: | isoform X3 |
| - Sequence: |
MTNQEKWAHLSPSEFSQLQKYAEYSTKKLKDVLEEFHGNGVLAKYNPEGTIDFEGFKLFMKTFLhide sequence |
| RefSeq Acc Id: | ENSRNOP00000058842 ⟸ ENSRNOT00000063874 |
TranscriptomeStrain Sequence Variants (Rnor 6.0)
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External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:2488 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000030771 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000058842 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000063874 | ENTREZGENE, UniProtKB/TrEMBL |
| Gene3D-CATH | 1.10.238.110 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| 3.40.50.10330 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| InterPro | ATP-NAD_kinase_N | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| DAG_kinase_typeI_N | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| DGK | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| DGK_typeI_N_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| Diacylglycerol_kin_accessory | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| Diacylglycerol_kinase_cat_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| EF-hand-dom_pair | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| EF_Hand_1_Ca_BS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| EF_hand_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| NAD/diacylglycerol_kinase_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| PE/DAG-bd | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| KEGG Report | rno:54248 | UniProtKB/Swiss-Prot |
| NCBI Gene | 54248 | ENTREZGENE |
| PANTHER | PTHR11255 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| Pfam | C1_1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| DAG_kinase_N | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| DAGK_acc | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| DAGK_cat | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| EF-hand_7 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| PhenoGen | Dgkb | PhenoGen |
| PROSITE | DAGK | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| EF_HAND_1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| EF_HAND_2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| ZF_DAG_PE_1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| ZF_DAG_PE_2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| SMART | DAGKa | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| DAGKc | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| EFh | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| SM00109 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| Superfamily-SCOP | SSF111331 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| SSF47473 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| TIGR | TC231297 | |
| UniGene | Rn.11413 | ENTREZGENE |
| UniProt | DGKB_RAT | UniProtKB/Swiss-Prot |
| F1LP01_RAT | UniProtKB/TrEMBL | |
| P49621 | ENTREZGENE |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2002-11-06 | Dgkb | diacylglycerol kinase, beta | Dagk | Diacylglycerol kinase 90kDa | Symbol and Name updated | 625702 | APPROVED |
| 2002-06-10 | Dagk | Diacylglycerol kinase 90kDa | Symbol and Name status set to approved | 70586 | APPROVED |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_cellular_localization | protein localized to membrane fractions | 728585 |
| gene_domains | protein contains an EF-hand motif, a cysteine-rich zinc-finger like sequence, and a putative ATP-binding site | 728585 |
| gene_expression | mRNA expressed specifically in neuronal populations, including caudate-putamen, accumbens nucleus and the olfactory tubercle | 728585 |
| gene_protein | 90 kDA protein is made up of 801 amino acids | 728585 |
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| More on Dgkb | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 2488 |
| Created: | 2000-05-25 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-08-20 |
| Status: | ACTIVE |
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.
