Cmpk2 (cytidine/uridine monophosphate kinase 2) - Rat Genome Database

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Gene: Cmpk2 (cytidine/uridine monophosphate kinase 2) Rattus norvegicus
Analyze
Symbol: Cmpk2
Name: cytidine/uridine monophosphate kinase 2
RGD ID: 1305881
Description: Enables UMP/dUMP kinase activity and thymidylate kinase activity. Involved in dTDP biosynthetic process and dUDP biosynthetic process. Predicted to be located in nucleoplasm. Predicted to be active in mitochondrion. Orthologous to human CMPK2 (cytidine/uridine monophosphate kinase 2); PARTICIPATES IN de novo pyrimidine biosynthetic pathway; beta-ureidopropionase deficiency pathway; dihydropyrimidinase deficiency pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial; LOC314004; thymidylate kinase family LPS-inducible member; Tyki; UMP-CMP kinase 2, mitochondrial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8648,802,150 - 48,813,652 (+)NCBIGRCr8
mRatBN7.2643,073,706 - 43,085,183 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl643,073,796 - 43,085,183 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx643,386,944 - 43,397,752 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0643,701,813 - 43,712,621 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0643,134,950 - 43,145,758 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0645,683,242 - 45,694,824 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl645,683,234 - 45,694,822 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0654,403,014 - 54,414,586 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4644,128,544 - 44,139,346 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1644,131,662 - 44,142,474 (+)NCBI
Celera642,340,630 - 42,351,433 (+)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
alpha-Zearalanol  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calciol  (ISO)
cannabidiol  (ISO)
captan  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chloroprene  (EXP)
choline  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
cyclosporin A  (ISO)
diclofenac  (ISO)
diethyl maleate  (EXP)
diethylstilbestrol  (EXP)
dioxygen  (EXP)
diuron  (EXP)
doxorubicin  (ISO)
flurbiprofen  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
GW 4064  (ISO)
hydroquinone  (ISO)
indometacin  (EXP)
iron dichloride  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
methapyrilene  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
niclosamide  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
PCB138  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
succimer  (ISO)
tamoxifen  (ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
toluene  (EXP)
topotecan  (EXP)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
Triptolide  (EXP)
trovafloxacin  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
mitochondrion  (IBA,ISO)
nucleoplasm  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Characterization of pyrimidine nucleoside monophosphokinase in normal and malignant tissues. Arima T, etal., Cancer Res. 1977 Jun;37(6):1593-7.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Long-term genome-wide blood RNA expression profiles yield novel molecular response candidates for IFN-beta-1b treatment in relapsing remitting MS. Goertsches RH, etal., Pharmacogenomics. 2010 Feb;11(2):147-61.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:7751651   PMID:17999954   PMID:23416111   PMID:35401582  


Genomics

Comparative Map Data
Cmpk2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8648,802,150 - 48,813,652 (+)NCBIGRCr8
mRatBN7.2643,073,706 - 43,085,183 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl643,073,796 - 43,085,183 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx643,386,944 - 43,397,752 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0643,701,813 - 43,712,621 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0643,134,950 - 43,145,758 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0645,683,242 - 45,694,824 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl645,683,234 - 45,694,822 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0654,403,014 - 54,414,586 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4644,128,544 - 44,139,346 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1644,131,662 - 44,142,474 (+)NCBI
Celera642,340,630 - 42,351,433 (+)NCBICelera
Cytogenetic Map6q16NCBI
CMPK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3826,840,553 - 6,866,635 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl26,840,570 - 6,866,635 (-)EnsemblGRCh38hg38GRCh38
GRCh3726,980,684 - 7,006,766 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3626,905,902 - 6,923,387 (-)NCBINCBI36Build 36hg18NCBI36
Celera26,901,418 - 6,918,887 (-)NCBICelera
Cytogenetic Map2p25.2NCBI
HuRef26,827,170 - 6,854,378 (-)NCBIHuRef
CHM1_126,910,237 - 6,936,319 (-)NCBICHM1_1
T2T-CHM13v2.026,862,071 - 6,888,137 (-)NCBIT2T-CHM13v2.0
Cmpk2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391226,519,121 - 26,529,836 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1226,519,203 - 26,529,836 (+)EnsemblGRCm39 Ensembl
GRCm381226,469,117 - 26,479,837 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1226,469,204 - 26,479,837 (+)EnsemblGRCm38mm10GRCm38
MGSCv371227,154,080 - 27,164,702 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361227,055,650 - 27,066,102 (+)NCBIMGSCv36mm8
Celera1227,927,424 - 27,938,075 (+)NCBICelera
Cytogenetic Map12A2NCBI
cM Map129.69NCBI
Cmpk2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554872,010,228 - 2,029,175 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554872,010,126 - 2,024,804 (+)NCBIChiLan1.0ChiLan1.0
CMPK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212119,646,173 - 119,663,765 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A119,650,157 - 119,667,740 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A6,856,242 - 6,874,567 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A6,985,922 - 7,013,703 (-)NCBIpanpan1.1PanPan1.1panPan2
CMPK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1174,466,615 - 4,478,546 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha174,392,411 - 4,405,578 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0174,569,103 - 4,582,289 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl174,569,983 - 4,582,289 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1174,456,522 - 4,469,702 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0174,465,166 - 4,478,340 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0174,478,967 - 4,492,134 (-)NCBIUU_Cfam_GSD_1.0
Cmpk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629249,140,895 - 49,153,365 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365323,895,755 - 3,908,367 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365323,896,654 - 3,908,184 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CMPK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3128,903,616 - 128,917,871 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13128,903,395 - 128,917,873 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23137,688,692 - 137,704,129 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CMPK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114100,804,295 - 100,820,565 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl14100,804,400 - 100,819,027 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604511,521,315 - 11,537,626 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cmpk2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248463,417,626 - 3,430,516 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248463,417,672 - 3,432,207 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cmpk2
54 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:457
Count of miRNA genes:229
Interacting mature miRNAs:285
Transcripts:ENSRNOT00000052003
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
8693632Alc27Alcohol consumption QTL 272.20.791drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)63432335751121479Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63330954957730294Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
738024Sach5Saccharine consumption QTL 53.90.00039consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)6143394190Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)62033877762613667Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)63569161857730540Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat

Markers in Region
BE101246  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2643,083,759 - 43,083,931 (+)MAPPERmRatBN7.2
Rnor_6.0645,693,396 - 45,693,567NCBIRnor6.0
Rnor_5.0654,413,161 - 54,413,332UniSTSRnor5.0
RGSC_v3.4644,137,923 - 44,138,094UniSTSRGSC3.4
Celera642,350,010 - 42,350,181UniSTS
RH 3.4 Map6258.7UniSTS
Cytogenetic Map6q16UniSTS
RH133559  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2643,084,804 - 43,085,018 (+)MAPPERmRatBN7.2
Rnor_6.0645,694,441 - 45,694,654NCBIRnor6.0
Rnor_5.0654,414,206 - 54,414,419UniSTSRnor5.0
RGSC_v3.4644,138,968 - 44,139,181UniSTSRGSC3.4
Celera642,351,055 - 42,351,268UniSTS
RH 3.4 Map6261.3UniSTS
Cytogenetic Map6q16UniSTS
RH134277  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2643,073,881 - 43,074,074 (+)MAPPERmRatBN7.2
Rnor_6.0645,683,518 - 45,683,710NCBIRnor6.0
Rnor_5.0654,403,283 - 54,403,475UniSTSRnor5.0
RGSC_v3.4644,128,045 - 44,128,237UniSTSRGSC3.4
Celera642,340,131 - 42,340,323UniSTS
RH 3.4 Map6256.2UniSTS
Cytogenetic Map6q16UniSTS
RH141869  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2643,084,081 - 43,084,279 (+)MAPPERmRatBN7.2
Rnor_6.0645,693,718 - 45,693,915NCBIRnor6.0
Rnor_5.0654,413,483 - 54,413,680UniSTSRnor5.0
RGSC_v3.4644,138,245 - 44,138,442UniSTSRGSC3.4
Celera642,350,332 - 42,350,529UniSTS
RH 3.4 Map6257.3UniSTS
Cytogenetic Map6q16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000052003   ⟹   ENSRNOP00000043468
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl643,073,796 - 43,085,183 (+)Ensembl
Rnor_6.0 Ensembl645,683,234 - 45,694,822 (+)Ensembl
RefSeq Acc Id: NM_001108017   ⟹   NP_001101487
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8648,802,850 - 48,813,652 (+)NCBI
mRatBN7.2643,074,381 - 43,085,183 (+)NCBI
Rnor_6.0645,684,017 - 45,694,819 (+)NCBI
Rnor_5.0654,403,014 - 54,414,586 (+)NCBI
RGSC_v3.4644,128,544 - 44,139,346 (+)RGD
Celera642,340,630 - 42,351,433 (+)RGD
Sequence:
RefSeq Acc Id: XM_063261895   ⟹   XP_063117965
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8648,802,150 - 48,810,590 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001101487 (Get FASTA)   NCBI Sequence Viewer  
  XP_063117965 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM03205 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000043468.5
RefSeq Acc Id: NP_001101487   ⟸   NM_001108017
- UniProtKB: A6HB00 (UniProtKB/TrEMBL),   D3ZC63 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000043468   ⟸   ENSRNOT00000052003
RefSeq Acc Id: XP_063117965   ⟸   XM_063261895
- Peptide Label: isoform X1
Protein Domains
Thymidylate kinase-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZC63-F1-model_v2 AlphaFold D3ZC63 1-447 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305881 AgrOrtholog
BioCyc Gene G2FUF-37994 BioCyc
BioCyc Pathway PWY-7176 [UTP and CTP de novo biosynthesis] BioCyc
  PWY-7197 [pyrimidine deoxyribonucleotide phosphorylation] BioCyc
  PWY-7205 [CMP phosphorylation] BioCyc
BioCyc Pathway Image PWY-7176 BioCyc
  PWY-7197 BioCyc
  PWY-7205 BioCyc
Ensembl Genes ENSRNOG00000007690 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000052003.6 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro dTMP_TKRP1 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Thymidylate_kin_like_dom UniProtKB/TrEMBL
KEGG Report rno:314004 UniProtKB/TrEMBL
NCBI Gene 314004 ENTREZGENE
PANTHER THYMIDYLATE KINASE UniProtKB/TrEMBL
  UMP-CMP KINASE 2, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam Thymidylate_kin UniProtKB/TrEMBL
PhenoGen Cmpk2 PhenoGen
PIRSF dTMP_TKRP1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007690 RatGTEx
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A6HB00 ENTREZGENE, UniProtKB/TrEMBL
  D3ZC63 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-27 Cmpk2  cytidine/uridine monophosphate kinase 2  Cmpk2  cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Cmpk2  cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial  Tyki_predicted  thymidylate kinase family LPS-inducible member (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Tyki_predicted  thymidylate kinase family LPS-inducible member (predicted)      Symbol and Name status set to approved 70820 APPROVED