Greb1 (growth regulating estrogen receptor binding 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Greb1 (growth regulating estrogen receptor binding 1) Rattus norvegicus
Analyze
Symbol: Greb1
Name: growth regulating estrogen receptor binding 1
RGD ID: 1564091
Description: Predicted to be involved in morphogenesis of an epithelium. Predicted to be located in membrane. Orthologous to human GREB1 (growth regulating estrogen receptor binding 1); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: growth regulation by estrogen in breast cancer 1; LOC500633; RGD1564091; similar to Kiaa0575
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8645,169,289 - 45,321,973 (-)NCBIGRCr8
mRatBN7.2639,440,522 - 39,562,364 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl639,440,504 - 39,581,633 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0641,932,941 - 42,002,770 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl641,932,244 - 42,002,819 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0651,661,849 - 51,735,066 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4640,356,449 - 40,406,966 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera638,750,684 - 38,822,218 (-)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R)-linalyl acetate  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,8-cineole  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3'-diindolylmethane  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-terpineol  (ISO)
4-tert-Octylphenol  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
alpha-terpineol  (ISO)
apigenin  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
bazedoxifene  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bicalutamide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
Butylparaben  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP)
caffeine  (ISO)
calcitriol  (ISO)
chlordecone  (ISO)
chrysene  (ISO)
chrysin  (ISO)
cisplatin  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
corticosterone  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
cyproterone  (ISO)
cyproterone acetate  (ISO)
daidzein  (ISO)
dapsone  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
Enterolactone  (ISO)
enzalutamide  (ISO)
ethisterone  (ISO)
ethylparaben  (ISO)
fenvalerate  (EXP)
fipronil  (ISO)
flutamide  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gamma-terpinene  (ISO)
genistein  (ISO)
glyphosate  (EXP,ISO)
hexestrol  (ISO)
Isobutylparaben  (ISO)
ivermectin  (ISO)
kaempferol  (ISO)
ketoconazole  (ISO)
lead diacetate  (ISO)
levonorgestrel  (ISO)
limonene  (ISO)
linalool  (ISO)
linalyl acetate  (ISO)
lipopolysaccharide  (ISO)
Lynestrenol  (ISO)
megestrol acetate  (ISO)
mestranol  (ISO)
methapyrilene  (ISO)
methoxychlor  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
methyltestosterone  (ISO)
mifepristone  (ISO)
molibresib  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-nitrosodiethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
nandrolone  (ISO)
nickel atom  (ISO)
nilutamide  (ISO)
norethisterone  (ISO)
Norethynodrel  (ISO)
O-methyleugenol  (ISO)
oxybenzone  (ISO)
p-tert-Amylphenol  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
picoxystrobin  (ISO)
pregnenolone  (ISO)
progesterone  (ISO)
propiconazole  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-adenosyl-L-methioninate  (ISO)
S-adenosyl-L-methionine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
spironolactone  (ISO)
tamoxifen  (ISO)
tea tree oil  (ISO)
tebufenpyrad  (ISO)
testosterone  (EXP,ISO)
testosterone undecanoate  (ISO)
tetraphene  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
valproic acid  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:18570454  


Genomics

Comparative Map Data
Greb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8645,169,289 - 45,321,973 (-)NCBIGRCr8
mRatBN7.2639,440,522 - 39,562,364 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl639,440,504 - 39,581,633 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0641,932,941 - 42,002,770 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl641,932,244 - 42,002,819 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0651,661,849 - 51,735,066 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4640,356,449 - 40,406,966 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera638,750,684 - 38,822,218 (-)NCBICelera
Cytogenetic Map6q16NCBI
GREB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38211,482,888 - 11,642,788 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl211,482,341 - 11,642,788 (+)EnsemblGRCh38hg38GRCh38
GRCh37211,674,171 - 11,782,914 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36211,591,693 - 11,700,363 (+)NCBINCBI36Build 36hg18NCBI36
Celera211,591,030 - 11,699,842 (+)NCBICelera
Cytogenetic Map2p25.1NCBI
HuRef211,524,429 - 11,634,440 (+)NCBIHuRef
CHM1_1211,603,825 - 11,712,536 (+)NCBICHM1_1
T2T-CHM13v2.0211,514,740 - 11,675,937 (+)NCBIT2T-CHM13v2.0
Greb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391216,720,616 - 16,851,395 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1216,720,616 - 16,850,887 (-)EnsemblGRCm39 Ensembl
GRCm381216,670,615 - 16,801,394 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1216,670,615 - 16,800,886 (-)EnsemblGRCm38mm10GRCm38
MGSCv371216,677,421 - 16,807,692 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361216,764,663 - 16,851,042 (-)NCBIMGSCv36mm8
MGSCv361216,697,105 - 16,782,721 (-)NCBIMGSCv36mm8
Celera1216,991,168 - 17,123,379 (-)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map128.0NCBI
Greb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554876,062,326 - 6,112,856 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554876,032,774 - 6,112,715 (+)NCBIChiLan1.0ChiLan1.0
GREB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212114,887,051 - 115,052,191 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A114,891,023 - 115,056,110 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A11,467,884 - 11,629,834 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A11,690,252 - 11,776,480 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A11,690,475 - 11,774,155 (+)Ensemblpanpan1.1panPan2
GREB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1178,250,941 - 8,327,398 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl178,252,134 - 8,325,886 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha178,168,172 - 8,258,445 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0178,340,333 - 8,430,410 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl178,339,665 - 8,429,548 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1178,225,077 - 8,315,326 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0178,228,411 - 8,318,693 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0178,247,815 - 8,338,321 (+)NCBIUU_Cfam_GSD_1.0
Greb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629252,637,359 - 52,760,217 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365327,451,348 - 7,515,259 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365327,392,705 - 7,515,242 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GREB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3125,099,935 - 125,171,036 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13125,099,352 - 125,233,965 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23133,942,984 - 133,972,487 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103220800
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11495,967,736 - 96,174,324 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1495,967,699 - 96,019,165 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604516,298,085 - 16,344,537 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Greb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248654,318,920 - 4,366,976 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248654,317,592 - 4,367,615 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Greb1
978 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:84
Count of miRNA genes:75
Interacting mature miRNAs:76
Transcripts:ENSRNOT00000032417
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
8693632Alc27Alcohol consumption QTL 272.20.791drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)63432335751121479Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63330954957730294Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6141223769Rat
738024Sach5Saccharine consumption QTL 53.90.00039consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)6143394190Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6141223769Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6141223769Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6142487980Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6142487980Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
7411584Foco4Food consumption QTL 44.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6142838846Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)62033877762613667Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)63569161857730540Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6142487980Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat

Markers in Region
D6Got44  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26130,547,128 - 130,547,310 (+)MAPPERmRatBN7.2
mRatBN7.2639,529,806 - 39,530,031 (+)MAPPERmRatBN7.2
Rnor_6.0642,029,730 - 42,029,954NCBIRnor6.0
Rnor_6.06135,960,578 - 135,960,759NCBIRnor6.0
Rnor_5.0651,750,498 - 51,750,722UniSTSRnor5.0
Rnor_5.06144,454,961 - 144,455,142UniSTSRnor5.0
RGSC_v3.4640,432,819 - 40,433,043UniSTSRGSC3.4
RGSC_v3.4640,432,818 - 40,433,043RGDRGSC3.4
RGSC_v3.4185,689,099 - 85,689,338RGDRGSC3.4
RGSC_v3.46136,267,462 - 136,267,643UniSTSRGSC3.4
RGSC_v3.1640,435,772 - 40,435,996RGD
Celera638,839,632 - 38,839,856UniSTS
Celera6128,103,012 - 128,103,193UniSTS
RH 3.4 Map6168.5RGD
RH 3.4 Map6168.5UniSTS
Cytogenetic Map6q15UniSTS
D6Got46  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2639,571,754 - 39,571,957 (+)MAPPERmRatBN7.2
Rnor_6.0642,071,776 - 42,071,978NCBIRnor6.0
Rnor_5.0651,791,215 - 51,791,417UniSTSRnor5.0
RGSC_v3.4640,473,548 - 40,473,752RGDRGSC3.4
RGSC_v3.4640,473,549 - 40,473,751UniSTSRGSC3.4
RGSC_v3.1640,476,501 - 40,476,705RGD
RH 3.4 Map6170.7RGD
RH 3.4 Map6170.7UniSTS
Cytogenetic Map6q15UniSTS
BM390559  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2639,442,156 - 39,442,326 (+)MAPPERmRatBN7.2
Rnor_6.0641,933,584 - 41,933,753NCBIRnor6.0
Rnor_5.0651,662,492 - 51,662,661UniSTSRnor5.0
Celera638,752,319 - 38,752,488UniSTS
RH 3.4 Map6171.0UniSTS
Cytogenetic Map6q15UniSTS
RH137615  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2639,454,449 - 39,454,572 (+)MAPPERmRatBN7.2
Rnor_6.0641,946,085 - 41,946,207NCBIRnor6.0
Rnor_5.0651,674,993 - 51,675,115UniSTSRnor5.0
Celera638,764,623 - 38,764,745UniSTS
Cytogenetic Map6q15UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 84 82 52 25 52 6 211 97 93 45 60 30

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001427084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003754164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003754165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006225731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006225732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000032417   ⟹   ENSRNOP00000036412
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl639,440,504 - 39,581,633 (-)Ensembl
Rnor_6.0 Ensembl641,932,244 - 42,002,819 (-)Ensembl
RefSeq Acc Id: NM_001427084   ⟹   NP_001414013
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,169,289 - 45,291,126 (-)NCBI
RefSeq Acc Id: XM_008764638   ⟹   XP_008762860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,169,289 - 45,291,095 (-)NCBI
mRatBN7.2639,440,522 - 39,562,362 (-)NCBI
Rnor_6.0641,932,941 - 42,002,770 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039113142   ⟹   XP_038969070
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,169,289 - 45,202,083 (-)NCBI
mRatBN7.2639,440,522 - 39,473,318 (-)NCBI
RefSeq Acc Id: XM_063262291   ⟹   XP_063118361
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,169,289 - 45,321,972 (-)NCBI
RefSeq Acc Id: XM_063262292   ⟹   XP_063118362
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,169,289 - 45,321,972 (-)NCBI
RefSeq Acc Id: XM_063262293   ⟹   XP_063118363
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,169,289 - 45,321,972 (-)NCBI
RefSeq Acc Id: XM_063262294   ⟹   XP_063118364
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,169,289 - 45,310,377 (-)NCBI
RefSeq Acc Id: XM_063262295   ⟹   XP_063118365
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,169,289 - 45,321,972 (-)NCBI
RefSeq Acc Id: XM_063262296   ⟹   XP_063118366
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,169,289 - 45,310,377 (-)NCBI
RefSeq Acc Id: XM_063262297   ⟹   XP_063118367
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,169,289 - 45,321,972 (-)NCBI
RefSeq Acc Id: XM_063262299   ⟹   XP_063118369
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,169,289 - 45,321,972 (-)NCBI
RefSeq Acc Id: XM_063262300   ⟹   XP_063118370
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,169,289 - 45,321,972 (-)NCBI
RefSeq Acc Id: XM_063262301   ⟹   XP_063118371
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,169,289 - 45,321,972 (-)NCBI
RefSeq Acc Id: XM_063262302   ⟹   XP_063118372
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,179,997 - 45,321,973 (-)NCBI
RefSeq Acc Id: XM_063262303   ⟹   XP_063118373
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,198,923 - 45,321,973 (-)NCBI
RefSeq Acc Id: XM_063262304   ⟹   XP_063118374
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8645,203,113 - 45,321,973 (-)NCBI
RefSeq Acc Id: XP_008762860   ⟸   XM_008764638
- Peptide Label: isoform X1
- UniProtKB: F1LW89 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000036412   ⟸   ENSRNOT00000032417
RefSeq Acc Id: XP_038969070   ⟸   XM_039113142
- Peptide Label: isoform X7
- UniProtKB: A6HAT2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118363   ⟸   XM_063262293
- Peptide Label: isoform X1
- UniProtKB: F1LW89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118362   ⟸   XM_063262292
- Peptide Label: isoform X1
- UniProtKB: F1LW89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118365   ⟸   XM_063262295
- Peptide Label: isoform X1
- UniProtKB: F1LW89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118369   ⟸   XM_063262299
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063118371   ⟸   XM_063262301
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063118370   ⟸   XM_063262300
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063118367   ⟸   XM_063262297
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063118361   ⟸   XM_063262291
- Peptide Label: isoform X1
- UniProtKB: F1LW89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118366   ⟸   XM_063262296
- Peptide Label: isoform X1
- UniProtKB: F1LW89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118364   ⟸   XM_063262294
- Peptide Label: isoform X1
- UniProtKB: F1LW89 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001414013   ⟸   NM_001427084
RefSeq Acc Id: XP_063118372   ⟸   XM_063262302
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063118373   ⟸   XM_063262303
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063118374   ⟸   XM_063262304
- Peptide Label: isoform X9
Protein Domains
GREB1 N-terminal   GREB1-like C-terminal   GREB1-like circularly permuted SF2 helicase   GREB1-like second   TET-Associated Glycosyltransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LW89-F1-model_v2 AlphaFold F1LW89 1-1946 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564091 AgrOrtholog
BioCyc Gene G2FUF-38064 BioCyc
Ensembl Genes ENSRNOG00000024651 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000032417.7 UniProtKB/TrEMBL
InterPro GREB1 UniProtKB/TrEMBL
  GREB1-like_2nd UniProtKB/TrEMBL
  GREB1-like_cpSF2 UniProtKB/TrEMBL
  GREB1_C UniProtKB/TrEMBL
  GREB1_N UniProtKB/TrEMBL
  TAGT UniProtKB/TrEMBL
NCBI Gene 500633 ENTREZGENE
PANTHER PROTEIN GREB1 UniProtKB/TrEMBL
  PTHR15720 UniProtKB/TrEMBL
Pfam cpSF2-GREB1 UniProtKB/TrEMBL
  GREB1 UniProtKB/TrEMBL
  GREB1_2nd UniProtKB/TrEMBL
  GREB1_C UniProtKB/TrEMBL
  TAGT UniProtKB/TrEMBL
PhenoGen Greb1 PhenoGen
RatGTEx ENSRNOG00000024651 RatGTEx
UniProt A6HAT2 ENTREZGENE, UniProtKB/TrEMBL
  F1LW89 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-04-04 Greb1  growth regulating estrogen receptor binding 1  Greb1  growth regulation by estrogen in breast cancer 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-11-25 Greb1  growth regulation by estrogen in breast cancer 1  RGD1564091  similar to Kiaa0575  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1564091  similar to Kiaa0575   RGD1564091_predicted  similar to Kiaa0575 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1564091_predicted  similar to Kiaa0575 (predicted)  LOC500633  similar to Kiaa0575  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC500633  similar to Kiaa0575      Symbol and Name status set to provisional 70820 PROVISIONAL