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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of POLR1F mRNA] | CTD | PMID:31150632 | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | RGD:1317243 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of POLR1F mRNA | CTD | PMID:22079256 | 1,2-dichloroethane | decreases expression | ISO | RGD:1317244 | 6480464 | ethylene dichloride results in decreased expression of POLR1F mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | decreases expression | ISO | RGD:1317244 | 6480464 | 1, 2-Dimethylhydrazine results in decreased expression of POLR1F mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:1317244 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of POLR1F mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:1317244 | 6480464 | Ethinyl Estradiol results in increased expression of POLR1F mRNA | CTD | PMID:17942748 | 17beta-estradiol | increases expression | ISO | RGD:1317243 | 6480464 | Estradiol results in increased expression of POLR1F mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1317244 | 6480464 | Tetrachlorodibenzodioxin affects the expression of POLR1F mRNA | CTD | PMID:21570461, PMID:24680724 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TWISTNB mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of POLR1F mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1317244 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of POLR1F mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1317244 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of POLR1F mRNA | CTD | PMID:19770486 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2, 4-dinitrotoluene affects the expression of POLR1F mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | increases expression | ISO | RGD:1317243 | 6480464 | Lactic Acid results in increased expression of POLR1F mRNA | CTD | PMID:30851411 | 4,4'-sulfonyldiphenol | increases methylation | ISO | RGD:1317243 | 6480464 | bis(4-hydroxyphenyl)sulfone results in increased methylation of POLR1F gene | CTD | PMID:31601247 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of TWISTNB mRNA | CTD | PMID:30047161 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of POLR1F mRNA | CTD | PMID:28959563 | aflatoxin B1 | decreases methylation | ISO | RGD:1317243 | 6480464 | Aflatoxin B1 results in decreased methylation of POLR1F gene | CTD | PMID:27153756 | aflatoxin M1 | decreases expression | ISO | RGD:1317243 | 6480464 | Aflatoxin M1 results in decreased expression of POLR1F mRNA | CTD | PMID:30928695 | all-trans-retinoic acid | decreases expression | ISO | RGD:1317243 | 6480464 | Tretinoin results in decreased expression of TWISTNB mRNA | CTD | PMID:33167477 | antirheumatic drug | decreases expression | ISO | RGD:1317243 | 6480464 | Antirheumatic Agents results in decreased expression of POLR1F mRNA | CTD | PMID:24449571 | arsenite(3-) | multiple interactions | ISO | RGD:1317243 | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to POLR1F mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | increases expression | ISO | RGD:1317244 | 6480464 | Benzo(a)pyrene results in increased expression of POLR1F mRNA | CTD | PMID:22228805 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of POLR1F mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of POLR1F mRNA | CTD | PMID:34947998 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of POLR1F gene | CTD | PMID:28505145 | caffeine | decreases phosphorylation | ISO | RGD:1317243 | 6480464 | Caffeine results in decreased phosphorylation of POLR1F protein | CTD | PMID:35688186 | CGP 52608 | multiple interactions | ISO | RGD:1317243 | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to TWISTNB gene] | CTD | PMID:28238834 | chlorpyrifos | decreases expression | ISO | RGD:1317244 | 6480464 | Chlorpyrifos results in decreased expression of POLR1F mRNA | CTD | PMID:37019170 | clofibrate | increases expression | ISO | RGD:1317244 | 6480464 | Clofibrate results in increased expression of POLR1F mRNA | CTD | PMID:23811191 | coumarin | increases phosphorylation | ISO | RGD:1317243 | 6480464 | coumarin results in increased phosphorylation of POLR1F protein | CTD | PMID:35688186 | cylindrospermopsin | increases expression | ISO | RGD:1317243 | 6480464 | cylindrospermopsin results in increased expression of POLR1F mRNA | CTD | PMID:24921660 | dicrotophos | decreases expression | ISO | RGD:1317243 | 6480464 | dicrotophos results in decreased expression of POLR1F mRNA | CTD | PMID:28302478 | disodium selenite | increases expression | ISO | RGD:1317243 | 6480464 | Sodium Selenite results in increased expression of POLR1F mRNA | CTD | PMID:18175754 | doxorubicin | decreases expression | ISO | RGD:1317243 | 6480464 | Doxorubicin results in decreased expression of POLR1F mRNA | CTD | PMID:29803840 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of POLR1F mRNA | CTD | PMID:24136188 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of POLR1F mRNA | CTD | PMID:22061828 | indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of POLR1F mRNA | CTD | PMID:21396975 | lipopolysaccharide | multiple interactions | ISO | RGD:1317243 | 6480464 | [S-(1, 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of TWISTNB mRNA | CTD | PMID:35811015 | lipopolysaccharide | increases expression | ISO | RGD:1317243 | 6480464 | Lipopolysaccharides results in increased expression of TWISTNB mRNA | CTD | PMID:35811015 | methyl methanesulfonate | decreases expression | ISO | RGD:1317243 | 6480464 | Methyl Methanesulfonate results in decreased expression of POLR1F mRNA | CTD | PMID:23649840 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of POLR1F mRNA | CTD | PMID:24136188 | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of TWISTNB mRNA | CTD | PMID:32680482 | pentachlorophenol | increases expression | ISO | RGD:1317244 | 6480464 | Pentachlorophenol results in increased expression of POLR1F mRNA | CTD | PMID:23892564 | pirinixic acid | increases expression | ISO | RGD:1317244 | 6480464 | pirinixic acid results in increased expression of POLR1F mRNA | CTD | PMID:18301758, PMID:23811191 | potassium chromate | increases expression | ISO | RGD:1317243 | 6480464 | potassium chromate(VI) results in increased expression of POLR1F mRNA | CTD | PMID:22079256 | potassium chromate | multiple interactions | ISO | RGD:1317243 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of POLR1F mRNA | CTD | PMID:22079256 | pyrogallol | increases expression | ISO | RGD:1317244 | 6480464 | Pyrogallol results in increased expression of POLR1F mRNA | CTD | PMID:20362636 | quercetin | increases phosphorylation | ISO | RGD:1317243 | 6480464 | Quercetin results in increased phosphorylation of POLR1F protein | CTD | PMID:35688186 | rac-lactic acid | increases expression | ISO | RGD:1317243 | 6480464 | Lactic Acid results in increased expression of POLR1F mRNA | CTD | PMID:30851411 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | RGD:1317243 | 6480464 | [S-(1, 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of TWISTNB mRNA | CTD | PMID:35811015 | sodium arsenite | affects methylation | ISO | RGD:1317243 | 6480464 | sodium arsenite affects the methylation of POLR1F gene | CTD | PMID:28589171 | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of POLR1F mRNA | CTD | PMID:25993096 | testosterone | decreases expression | ISO | RGD:1317243 | 6480464 | Testosterone results in decreased expression of TWISTNB mRNA | CTD | PMID:33359661 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of POLR1F mRNA | CTD | PMID:31150632 | tetrachloromethane | increases expression | ISO | RGD:1317244 | 6480464 | Carbon Tetrachloride results in increased expression of POLR1F mRNA | CTD | PMID:31919559 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of POLR1F mRNA] | CTD | PMID:31150632 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of POLR1F mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | ISO | RGD:1317244 | 6480464 | titanium dioxide results in decreased expression of POLR1F mRNA | CTD | PMID:19464567 | valproic acid | increases expression | ISO | RGD:1317243 | 6480464 | Valproic Acid results in increased expression of POLR1F mRNA | CTD | PMID:28001369, PMID:29154799 | |