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Gene: Slc26a4 (solute carrier family 26 member 4) Rattus norvegicus
Symbol: Slc26a4
Name: solute carrier family 26 member 4
RGD ID: 3293
Description: Exhibits chloride transmembrane transporter activity and iodide transmembrane transporter activity. Involved in inorganic anion transport. Localizes to apical plasma membrane. Human ortholog(s) of this gene implicated in Pendred Syndrome; autosomal recessive nonsyndromic deafness 4; and goiter. Orthologous to human SLC26A4 (solute carrier family 26 member 4); PARTICIPATES IN thyroid hormone biosynthetic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; amiloride.
Type: protein-coding
Also known as: Pds; Pendred syndrome homolog; pendred syndrome homolog (human); pendrin; sodium-independent chloride/iodide transporter; solute carrier family 26 (anion exchanger), member 4; solute carrier family 26, member 4
Homo sapiens (human) : SLC26A4 (solute carrier family 26 member 4)  HGNC  Alliance
Mus musculus (house mouse) : Slc26a4 (solute carrier family 26, member 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc26a4 (solute carrier family 26 member 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC26A4 (solute carrier family 26 member 4)
Canis lupus familiaris (dog) : SLC26A4 (solute carrier family 26 member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc26a4 (solute carrier family 26 member 4)
Sus scrofa (pig) : SLC26A4 (solute carrier family 26 member 4)
Chlorocebus sabaeus (African green monkey) : SLC26A4 (solute carrier family 26 member 4)
Heterocephalus glaber (naked mole-rat) : Slc26a4 (solute carrier family 26 member 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0650,809,103 - 50,848,443 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl650,808,923 - 50,846,965 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0659,479,842 - 59,520,531 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4649,389,212 - 49,427,000 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1649,392,337 - 49,430,126 (-)NCBI
Celera647,310,126 - 47,347,924 (-)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Slc26a4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3293
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.