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Gene: Prkar2b (protein kinase cAMP-dependent type II regulatory subunit beta) Rattus norvegicus
Symbol: Prkar2b
Name: protein kinase cAMP-dependent type II regulatory subunit beta
Description: Exhibits cAMP binding activity; cAMP-dependent protein kinase regulator activity; and protein domain specific binding activity. Involved in regulation of protein kinase activity and response to clozapine. Localizes to several cellular components, including cAMP-dependent protein kinase complex; membrane raft; and neuronal cell body. Orthologous to human PRKAR2B (protein kinase cAMP-dependent type II regulatory subunit beta); PARTICIPATES IN protein kinase A (PKA) signaling pathway; apoptotic cell death pathway; insulin signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cAMP-dependent protein kinase type II-beta regulatory subunit; MGC116401; protein kinase cAMP-dependent type 2 regulatory subunit beta; protein kinase, cAMP dependent regulatory, type II beta; protein kinase, cAMP-dependent, regulatory subunit type II beta; RATDNA; type II beta regulatory subunit of cAMP-dependent protein kinase
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0651,265,509 - 51,356,383 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl651,265,515 - 51,356,383 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0659,936,123 - 60,027,242 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4650,234,979 - 50,325,298 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1650,238,107 - 50,306,399 (-)NCBI
Celera647,765,297 - 47,855,503 (-)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Prkar2b
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3394
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.