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Gene: PRKAR2A (protein kinase cAMP-dependent type II regulatory subunit alpha) Homo sapiens
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Symbol: PRKAR2A
Name: protein kinase cAMP-dependent type II regulatory subunit alpha
Description: Exhibits cAMP-dependent protein kinase inhibitor activity; enzyme binding activity; and protein domain specific binding activity. Involved in negative regulation of cAMP-dependent protein kinase activity. Localizes to several cellular components, including cAMP-dependent protein kinase complex; centrosome; and nucleotide-activated protein kinase complex. Colocalizes with axoneme. Implicated in congestive heart failure.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cAMP-dependent protein kinase regulatory subunit RII alpha; cAMP-dependent protein kinase type II-alpha regulatory subunit; MGC3606; PKR2; PRKAR2; protein kinase A, RII-alpha subunit; protein kinase, camp-dependent, regulatory, type 2, alpha
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl348,744,597 - 48,847,874 (-)EnsemblGRCh38hg38GRCh38
GRCh38348,744,601 - 48,847,874 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37348,784,017 - 48,885,270 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36348,763,097 - 48,860,274 (-)NCBINCBI36hg18NCBI36
Build 34348,763,096 - 48,860,274NCBI
Celera348,744,318 - 48,841,506 (-)NCBI
Cytogenetic Map3p21.31NCBI
HuRef348,846,714 - 48,943,468 (-)NCBIHuRef
CHM1_1348,736,104 - 48,837,385 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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RNA-SEQ Expression

Sequence

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Additional Information

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Nomenclature History
 
More on PRKAR2A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732434
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.