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Gene: Fbxo33 (F-box protein 33) Rattus norvegicus

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Symbol:

Fbxo33

Name:

F-box protein 33

RGD ID:

1307543

Description:

Predicted to be involved in positive regulation of protein ubiquitination. Orthologous to human FBXO33 (F-box protein 33); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; atrazine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

F-box only protein 33; LOC314157

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FBXO33 (F-box protein 33)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Fbxo33 (F-box protein 33)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Fbxo33 (F-box protein 33)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FBXO33 (F-box protein 33)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FBXO33 (F-box protein 33)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Fbxo33 (F-box protein 33)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FBXO33 (F-box protein 33)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	FBXO33 (F-box protein 33)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Fbxo33 (F-box protein 33)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	FBXO33 (F-box protein 33)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Fbxo33 (F-box protein 33)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG4911	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	fbxo33	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	82,635,509 - 82,669,441 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	82,635,521 - 82,667,440 (-)	Ensembl				GRCr8
mRatBN7.2	6	76,900,619 - 76,934,232 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	76,900,631 - 76,932,669 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	77,339,433 - 77,371,258 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	77,638,764 - 77,670,589 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	77,066,239 - 77,098,064 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	80,302,291 - 80,334,536 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	80,302,303 - 80,334,522 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	89,828,077 - 89,860,407 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	79,902,508 - 79,934,591 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	75,655,646 - 75,687,363 (-)	NCBI		Celera
RGSC_v3.1	6	79,905,965 - 80,032,484 (-)	NCBI
Cytogenetic Map	6	q23	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Brain-Lung-Thyroid Syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

atrazine (EXP,ISO)

Benoxacor (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

chlordecone (ISO)

clothianidin (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

diclofenac (ISO)

dicrotophos (ISO)

ethanol (ISO)

fluoranthene (ISO)

gentamycin (EXP)

GSK-J4 (ISO)

inulin (ISO)

lead diacetate (ISO)

methamphetamine (EXP)

okadaic acid (ISO)

oxaliplatin (EXP)

ozone (ISO)

p-toluidine (EXP)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

potassium chloride (ISO)

silver atom (ISO)

silver(0) (ISO)

Soman (EXP)

sunitinib (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

topotecan (EXP)

trichloroethene (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

trovafloxacin (ISO)

tungsten (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vincristine (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of protein ubiquitination (IBA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Fbxo33
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	82,635,509 - 82,669,441 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	82,635,521 - 82,667,440 (-)	Ensembl				GRCr8
mRatBN7.2	6	76,900,619 - 76,934,232 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	76,900,631 - 76,932,669 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	77,339,433 - 77,371,258 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	77,638,764 - 77,670,589 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	77,066,239 - 77,098,064 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	80,302,291 - 80,334,536 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	80,302,303 - 80,334,522 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	89,828,077 - 89,860,407 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	79,902,508 - 79,934,591 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	75,655,646 - 75,687,363 (-)	NCBI		Celera
RGSC_v3.1	6	79,905,965 - 80,032,484 (-)	NCBI
Cytogenetic Map	6	q23	NCBI

FBXO33
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	39,397,684 - 39,432,433 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	39,397,684 - 39,432,466 (-)	Ensembl			hg38	GRCh38
GRCh37	14	39,866,888 - 39,901,637 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	38,936,710 - 38,971,371 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	14	38,936,710 - 38,971,371	NCBI
Celera	14	19,731,269 - 19,768,589 (-)	NCBI		Celera
Cytogenetic Map	14	q21.1	NCBI
HuRef	14	19,979,341 - 20,016,798 (-)	NCBI		HuRef
CHM1_1	14	39,864,175 - 39,900,294 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	14	33,586,312 - 33,624,046 (-)	NCBI		T2T-CHM13v2.0

Fbxo33
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	59,247,441 - 59,268,747 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	59,247,441 - 59,266,511 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	12	59,200,655 - 59,221,961 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	59,200,655 - 59,219,725 (-)	Ensembl			mm10	GRCm38
MGSCv37	12	60,301,642 - 60,320,470 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	12	60,118,668 - 60,123,701 (-)	NCBI		MGSCv36	mm8
Celera	12	60,360,719 - 60,379,552 (-)	NCBI		Celera
Cytogenetic Map	12	C1	NCBI
cM Map	12	26.03	NCBI

Fbxo33
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	21,930,071 - 21,951,068 (+)	Ensembl
ChiLan1.0	NW_004955409	21,929,863 - 21,952,812 (+)	NCBI	ChiLan1.0	ChiLan1.0

FBXO33
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	40,733,689 - 40,768,479 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	39,950,273 - 39,984,993 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	20,170,332 - 20,205,181 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	38,524,595 - 38,558,579 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	38,526,437 - 38,558,626 (-)	Ensembl			panPan2	panpan1.1

FBXO33
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	17,495,795 - 17,528,389 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	17,462,937 - 17,528,249 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	17,306,963 - 17,339,769 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	17,618,241 - 17,651,061 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	17,620,015 - 17,650,706 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	17,305,526 - 17,338,338 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	17,377,487 - 17,410,316 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	17,664,179 - 17,696,816 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Fbxo33
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	49,424,759 - 49,463,370 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936494	12,929,814 - 12,969,479 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936494	12,930,659 - 12,969,264 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FBXO33
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	169,877,197 - 169,915,798 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	169,877,189 - 169,915,856 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	188,588,681 - 188,627,424 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FBXO33
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	16,174,116 - 16,206,955 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	16,175,882 - 16,207,155 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666053	5,273,799 - 5,306,227 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fbxo33
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624813	8,791,774 - 8,812,916 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624813	8,791,774 - 8,812,870 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Fbxo33
170 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	643
Count of miRNA genes:	292
Interacting mature miRNAs:	359
Transcripts:	ENSRNOT00000059316
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
9590290	Uminl2	Urine mineral level QTL 2	3.96	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	6	38783989	83783989	Rat
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	72202632	130919985	Rat
634307	Bp141	Blood pressure QTL 141	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	35230417	80230417	Rat
634330	Pia16	Pristane induced arthritis QTL 16	3.9		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	6	45790088	104200226	Rat
1331789	Rf37	Renal function QTL 37	3.224		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	6	72202632	115200186	Rat
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	10894415	110548006	Rat
70176	Mcsm1	Mammary carcinoma susceptibility modifier QTL 1			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	58632962	103632962	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	72227641	130729205	Rat
1558641	Cm47	Cardiac mass QTL 47	2.9	0.001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	6	57730540	104085867	Rat
724524	Uae2	Urinary albumin excretion QTL 2	2.7	0.0005	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	73463459	109394713	Rat
1641904	Alcrsp4	Alcohol response QTL 4			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	6	67262953	112262953	Rat
2293839	Kiddil2	Kidney dilation QTL 2	4.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	20866422	81133036	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	15107216	107351382	Rat
731173	Uae22	Urinary albumin excretion QTL 22	10.1		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
9590140	Scort4	Serum corticosterone level QTL 4	14.49	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	38783989	83783989	Rat
2301964	Bp323	Blood pressure QTL 323	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	72227641	81132889	Rat
9590306	Scort18	Serum corticosterone level QTL 18	2.88	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	38783989	83783989	Rat
2293841	Kiddil4	Kidney dilation QTL 4	4.4		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	20866422	81133036	Rat
4889848	Pur25	Proteinuria QTL 25	14	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	56728562	90198260	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	72202632	130729475	Rat
70196	BpQTLcluster7	Blood pressure QTL cluster 7	6.82		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	72202632	117202632	Rat
6893340	Cm77	Cardiac mass QTL 77	0.26	0.57	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	33309549	81132889	Rat
1581550	Pur8	Proteinuria QTL 8			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	72227641	130729205	Rat
1300075	Glom7	Glomerulus QTL 7	5.6	0.0000002	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	6	71201409	116201409	Rat
2290393	Uae37	Urinary albumin excretion QTL 37		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
1300143	Rf14	Renal function QTL 14	2.92		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	34434137	77102317	Rat
12801471	Schws9	Schwannoma susceptibility QTL 9			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	61747639	106747639	Rat
6893332	Cm74	Cardiac mass QTL 74	0.4	0.64	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	57730540	104085867	Rat

Markers in Region

D6Rat98

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	6	82,657,553 - 82,657,762 (+)	Marker Load Pipeline
mRatBN7.2	6	76,922,663 - 76,922,872 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	80,324,849 - 80,325,057	NCBI	Rnor6.0
Rnor_5.0	6	89,850,635 - 89,850,843	UniSTS	Rnor5.0
RGSC_v3.4	6	79,924,547 - 79,924,756	RGD	RGSC3.4
RGSC_v3.4	6	79,924,548 - 79,924,756	UniSTS	RGSC3.4
Celera	6	75,677,690 - 75,677,898	UniSTS
RGSC_v3.1	6	79,928,004 - 79,928,212	RGD
RH 3.4 Map	6	546.1	RGD
RH 3.4 Map	6	546.1	UniSTS
RH 2.0 Map	6	768.9	RGD
SHRSP x BN Map	6	51.1399	RGD
FHH x ACI Map	6	60.2299	RGD
Cytogenetic Map	6	q23	UniSTS

AI642135

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	76,900,767 - 76,900,873 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	80,302,440 - 80,302,545	NCBI	Rnor6.0
Rnor_5.0	6	89,828,226 - 89,828,331	UniSTS	Rnor5.0
RGSC_v3.4	6	79,902,652 - 79,902,757	UniSTS	RGSC3.4
Celera	6	75,655,790 - 75,655,895	UniSTS
Cytogenetic Map	6	q23	UniSTS

RH135434

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	76,900,678 - 76,900,861 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	80,302,351 - 80,302,533	NCBI	Rnor6.0
Rnor_5.0	6	89,828,137 - 89,828,319	UniSTS	Rnor5.0
RGSC_v3.4	6	79,902,563 - 79,902,745	UniSTS	RGSC3.4
Celera	6	75,655,701 - 75,655,883	UniSTS
RH 3.4 Map	6	546.69	UniSTS
Cytogenetic Map	6	q23	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001399654	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112237	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112238	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC168929	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ234808	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ234911	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000059316 ⟹ ENSRNOP00000056078

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	76,900,631 - 76,932,337 (-)	Ensembl
Rnor_6.0 Ensembl	6	80,302,303 - 80,334,522 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094790 ⟹ ENSRNOP00000091589

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	82,635,521 - 82,667,440 (-)	Ensembl
mRatBN7.2 Ensembl	6	76,900,631 - 76,932,669 (-)	Ensembl

RefSeq Acc Id:

NM_001399654 ⟹ NP_001386583

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	82,635,509 - 82,667,227 (-)	NCBI
mRatBN7.2	6	76,900,619 - 76,932,337 (-)	NCBI

RefSeq Acc Id:

XM_039112237 ⟹ XP_038968165

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	82,635,511 - 82,669,441 (-)	NCBI
mRatBN7.2	6	76,900,619 - 76,934,232 (-)	NCBI

RefSeq Acc Id:

XM_039112238 ⟹ XP_038968166

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	82,635,511 - 82,667,382 (-)	NCBI
mRatBN7.2	6	76,900,619 - 76,932,493 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001386583	(Get FASTA)	NCBI Sequence Viewer
	XP_038968165	(Get FASTA)	NCBI Sequence Viewer
	XP_038968166	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI68929	(Get FASTA)	NCBI Sequence Viewer
	EDM03471	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000056078.2
	ENSRNOP00000091589
	ENSRNOP00000091589.1

Ensembl Acc Id:

ENSRNOP00000056078 ⟸ ENSRNOT00000059316

RefSeq Acc Id:	XP_038968165 ⟸ XM_039112237
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038968166 ⟸ XM_039112238
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000091589 ⟸ ENSRNOT00000094790

RefSeq Acc Id:	NP_001386583 ⟸ NM_001399654
- UniProtKB:	A6HBR6 (UniProtKB/TrEMBL), D3ZVL5 (UniProtKB/TrEMBL)

Protein Domains

F-box

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZVL5-F1-model_v2	AlphaFold	D3ZVL5	1-467	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694619

Promoter ID:

EPDNEW_R5143

Type:

initiation region

Name:

Fbxo33_1

Description:

F-box protein 33

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	80,334,540 - 80,334,600	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307543	AgrOrtholog
BioCyc Gene	G2FUF-37379	BioCyc
Ensembl Genes	ENSRNOG00000005285	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000059316.3	UniProtKB/TrEMBL
	ENSRNOT00000094790	ENTREZGENE
	ENSRNOT00000094790.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1280.50	UniProtKB/TrEMBL
	3.80.10.10	UniProtKB/TrEMBL
InterPro	F-box_dom_cyclin-like	UniProtKB/TrEMBL
	F-box_dom_like	UniProtKB/TrEMBL
	L_dom-like	UniProtKB/TrEMBL
NCBI Gene	314157	ENTREZGENE
PANTHER	F-BOX ONLY PROTEIN 33	UniProtKB/TrEMBL
	PTHR20933	UniProtKB/TrEMBL
Pfam	F-box-like	UniProtKB/TrEMBL
PhenoGen	Fbxo33	PhenoGen
PROSITE	FBOX	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000005285	RatGTEx
SMART	FBOX	UniProtKB/TrEMBL
Superfamily-SCOP	F-box_dom_Skp2-like	UniProtKB/TrEMBL
UniProt	A0A8I6ADZ5_RAT	UniProtKB/TrEMBL
	A6HBR6	ENTREZGENE, UniProtKB/TrEMBL
	B5DF53_RAT	UniProtKB/TrEMBL
	D3ZVL5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-04	Fbxo33	F-box protein 33	Fbxo33_predicted	F-box only protein 33 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Fbxo33_predicted	F-box only protein 33 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar