Itgb1bp1 (integrin subunit beta 1 binding protein 1) - Rat Genome Database

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Gene: Itgb1bp1 (integrin subunit beta 1 binding protein 1) Rattus norvegicus
Analyze
Symbol: Itgb1bp1
Name: integrin subunit beta 1 binding protein 1
RGD ID: 1307810
Description: Predicted to enable GDP-dissociation inhibitor activity; integrin binding activity; and protein kinase binding activity. Predicted to be involved in several processes, including regulation of cell migration; regulation of cell-substrate adhesion; and regulation of signal transduction. Predicted to be located in several cellular components, including centriolar satellite; nuclear body; and perinuclear region of cytoplasm. Predicted to be active in several cellular components, including cytoskeleton; lamellipodium; and ruffle. Orthologous to human ITGB1BP1 (integrin subunit beta 1 binding protein 1); PARTICIPATES IN integrin mediated signaling pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: integrin beta 1 binding protein 1; integrin beta-1-binding protein 1; LOC298914
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2640,820,693 - 40,836,074 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl640,821,339 - 40,836,037 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx641,143,504 - 41,157,832 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0641,458,196 - 41,472,523 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0640,891,459 - 40,905,787 (-)NCBIRnor_WKY
Rnor_6.0643,348,927 - 43,363,633 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl643,348,958 - 43,363,335 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0660,216,633 - 60,231,381 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4641,830,110 - 41,844,514 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1641,833,498 - 41,847,916 (-)NCBI
Celera640,108,431 - 40,122,817 (-)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of protein kinase B activity  (ISO)
blood vessel diameter maintenance  (ISO)
blood vessel endothelial cell proliferation involved in sprouting angiogenesis  (ISO)
cell-matrix adhesion  (ISO)
cellular response to fibroblast growth factor stimulus  (ISO)
cellular response to vascular endothelial growth factor stimulus  (ISO)
integrin activation  (ISO)
integrin-mediated signaling pathway  (ISO)
myoblast migration  (ISO)
negative regulation of cell adhesion involved in substrate-bound cell migration  (ISO)
negative regulation of cell migration involved in sprouting angiogenesis  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of ERK1 and ERK2 cascade  (ISO)
negative regulation of fibroblast migration  (ISO)
negative regulation of focal adhesion assembly  (IBA,ISO)
negative regulation of protein binding  (ISO)
negative regulation of protein kinase activity  (ISO)
negative regulation of protein targeting to membrane  (ISO)
negative regulation of substrate adhesion-dependent cell spreading  (IBA,ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of endothelial cell migration  (ISO)
positive regulation of focal adhesion assembly  (ISO)
positive regulation of Notch signaling pathway  (ISO)
positive regulation of protein kinase B signaling  (ISO)
positive regulation of protein targeting to membrane  (ISO)
positive regulation of stress fiber assembly  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
protein localization to plasma membrane  (ISO)
receptor clustering  (ISO)
regulation of cell adhesion mediated by integrin  (ISO)
regulation of GTPase activity  (ISO)
regulation of integrin-mediated signaling pathway  (ISO)
tube formation  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Integrin inactivators: balancing cellular functions in vitro and in vivo. Bouvard D, etal., Nat Rev Mol Cell Biol. 2013 Jul;14(7):430-42. doi: 10.1038/nrm3599. Epub 2013 May 30.
2. Talins and kindlins: partners in integrin-mediated adhesion. Calderwood DA, etal., Nat Rev Mol Cell Biol. 2013 Aug;14(8):503-17. doi: 10.1038/nrm3624. Epub 2013 Jul 17.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9281591   PMID:11807099   PMID:11919189   PMID:12473654   PMID:12477932   PMID:15703214   PMID:16741948   PMID:17654484   PMID:17916086   PMID:18227284   PMID:20616313   PMID:23376485  


Genomics

Comparative Map Data
Itgb1bp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2640,820,693 - 40,836,074 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl640,821,339 - 40,836,037 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx641,143,504 - 41,157,832 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0641,458,196 - 41,472,523 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0640,891,459 - 40,905,787 (-)NCBIRnor_WKY
Rnor_6.0643,348,927 - 43,363,633 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl643,348,958 - 43,363,335 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0660,216,633 - 60,231,381 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4641,830,110 - 41,844,514 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1641,833,498 - 41,847,916 (-)NCBI
Celera640,108,431 - 40,122,817 (-)NCBICelera
Cytogenetic Map6q16NCBI
ITGB1BP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3829,403,475 - 9,423,569 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl29,403,475 - 9,423,528 (-)EnsemblGRCh38hg38GRCh38
GRCh3729,543,604 - 9,563,698 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3629,463,264 - 9,481,094 (-)NCBINCBI36Build 36hg18NCBI36
Build 3429,496,414 - 9,514,233NCBI
Celera29,457,992 - 9,475,539 (-)NCBICelera
Cytogenetic Map2p25.1NCBI
HuRef29,391,245 - 9,409,126 (-)NCBIHuRef
CHM1_129,475,472 - 9,493,078 (-)NCBICHM1_1
T2T-CHM13v2.029,428,778 - 9,448,648 (-)NCBIT2T-CHM13v2.0
Itgb1bp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391221,317,247 - 21,336,285 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1221,290,826 - 21,336,285 (-)EnsemblGRCm39 Ensembl
GRCm381221,267,246 - 21,286,292 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1221,240,825 - 21,286,284 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl1221,267,420 - 21,286,284 (-)EnsemblGRCm38mm10GRCm38
MGSCv371221,275,667 - 21,292,098 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361221,516,296 - 21,532,727 (-)NCBIMGSCv36mm8
Celera1219,618,971 - 19,635,133 (+)NCBICelera
Cytogenetic Map12A1.3NCBI
Itgb1bp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554875,134,135 - 5,146,449 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554875,134,135 - 5,146,449 (-)NCBIChiLan1.0ChiLan1.0
ITGB1BP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A9,559,416 - 9,576,899 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A9,556,857 - 9,577,155 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A9,396,553 - 9,413,408 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ITGB1BP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1176,524,602 - 6,537,321 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl176,524,613 - 6,537,233 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha176,452,429 - 6,465,110 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0176,623,442 - 6,636,129 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl176,623,416 - 6,636,121 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1176,515,976 - 6,528,650 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0176,518,396 - 6,531,054 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0176,531,756 - 6,544,438 (-)NCBIUU_Cfam_GSD_1.0
Itgb1bp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629251,047,715 - 51,059,189 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365325,799,342 - 5,814,199 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365325,802,761 - 5,814,226 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITGB1BP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3126,905,810 - 126,922,045 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13126,905,779 - 126,921,961 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23135,174,258 - 135,295,240 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ITGB1BP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11498,226,666 - 98,244,094 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1498,230,100 - 98,248,862 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604514,079,143 - 14,096,391 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Itgb1bp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624969290,570 - 301,189 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624969290,601 - 307,152 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Itgb1bp1
96 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:74
Count of miRNA genes:58
Interacting mature miRNAs:69
Transcripts:ENSRNOT00000009401
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6141223769Rat
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6141223769Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6141223769Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6142487980Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6142487980Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6142487980Rat
7411584Foco4Food consumption QTL 44.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6142838846Rat
738024Sach5Saccharine consumption QTL 53.90.00039consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)6143394190Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)62033877762613667Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63330954957730294Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)63569161857730540Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat

Markers in Region
D6Got50  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2640,832,154 - 40,832,315 (+)MAPPERmRatBN7.2
Rnor_6.0643,359,743 - 43,359,903NCBIRnor6.0
Rnor_5.0660,227,449 - 60,227,609UniSTSRnor5.0
RGSC_v3.4641,840,921 - 41,841,082RGDRGSC3.4
RGSC_v3.4641,840,922 - 41,841,082UniSTSRGSC3.4
RGSC_v3.1641,844,048 - 41,844,208RGD
Celera640,119,243 - 40,119,385UniSTS
RH 3.4 Map6223.4UniSTS
RH 3.4 Map6223.4RGD
RH 2.0 Map6375.1RGD
Cytogenetic Map6q16UniSTS
RH143075  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2640,825,459 - 40,825,759 (+)MAPPERmRatBN7.2
Rnor_6.0643,353,049 - 43,353,348NCBIRnor6.0
Rnor_5.0660,220,755 - 60,221,054UniSTSRnor5.0
RGSC_v3.4641,834,228 - 41,834,527UniSTSRGSC3.4
Celera640,112,549 - 40,112,848UniSTS
RH 3.4 Map6223.5UniSTS
Cytogenetic Map6q16UniSTS
AI449260  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2640,822,278 - 40,822,362 (+)MAPPERmRatBN7.2
Rnor_6.0643,349,868 - 43,349,951NCBIRnor6.0
Rnor_5.0660,217,574 - 60,217,657UniSTSRnor5.0
RGSC_v3.4641,831,047 - 41,831,130UniSTSRGSC3.4
Celera640,109,368 - 40,109,451UniSTS
Cytogenetic Map6q16UniSTS
RH141519  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2640,821,372 - 40,821,583 (+)MAPPERmRatBN7.2
Rnor_6.0643,348,962 - 43,349,172NCBIRnor6.0
Rnor_5.0660,216,668 - 60,216,878UniSTSRnor5.0
RGSC_v3.4641,830,141 - 41,830,351UniSTSRGSC3.4
Celera640,108,462 - 40,108,672UniSTS
Cytogenetic Map6q16UniSTS
BG372800  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2640,825,142 - 40,825,276 (+)MAPPERmRatBN7.2
Rnor_6.0643,352,732 - 43,352,865NCBIRnor6.0
Rnor_5.0660,220,438 - 60,220,571UniSTSRnor5.0
RGSC_v3.4641,833,911 - 41,834,044UniSTSRGSC3.4
Celera640,112,232 - 40,112,365UniSTS
RH 3.4 Map6221.0UniSTS
Cytogenetic Map6q16UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000092192   ⟹   ENSRNOP00000071708
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl640,821,342 - 40,836,037 (-)Ensembl
Rnor_6.0 Ensembl643,348,958 - 43,363,335 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000103709   ⟹   ENSRNOP00000095877
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl640,821,626 - 40,836,012 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000116410   ⟹   ENSRNOP00000086750
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl640,821,339 - 40,825,790 (-)Ensembl
RefSeq Acc Id: NM_001106719   ⟹   NP_001100189
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2640,821,342 - 40,835,747 (-)NCBI
Rnor_6.0643,348,931 - 43,363,335 (-)NCBI
Rnor_5.0660,216,633 - 60,231,381 (-)NCBI
RGSC_v3.4641,830,110 - 41,844,514 (-)RGD
Celera640,108,431 - 40,122,817 (-)RGD
Sequence:
RefSeq Acc Id: XM_006239979   ⟹   XP_006240041
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2640,821,338 - 40,836,073 (-)NCBI
Rnor_6.0643,348,927 - 43,363,633 (-)NCBI
Rnor_5.0660,216,633 - 60,231,381 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239980   ⟹   XP_006240042
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2640,821,338 - 40,836,074 (-)NCBI
Rnor_6.0643,348,927 - 43,363,633 (-)NCBI
Rnor_5.0660,216,633 - 60,231,381 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239981   ⟹   XP_006240043
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2640,821,338 - 40,835,894 (-)NCBI
Rnor_6.0643,348,927 - 43,363,491 (-)NCBI
Rnor_5.0660,216,633 - 60,231,381 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039111950   ⟹   XP_038967878
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2640,820,693 - 40,834,831 (-)NCBI
RefSeq Acc Id: XM_039111951   ⟹   XP_038967879
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2640,821,338 - 40,836,074 (-)NCBI
RefSeq Acc Id: XM_039111952   ⟹   XP_038967880
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2640,821,338 - 40,835,894 (-)NCBI
RefSeq Acc Id: XM_039111953   ⟹   XP_038967881
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2640,821,338 - 40,836,074 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001100189   ⟸   NM_001106719
- UniProtKB: B5DFL3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240041   ⟸   XM_006239979
- Peptide Label: isoform X1
- UniProtKB: B5DFL3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240042   ⟸   XM_006239980
- Peptide Label: isoform X1
- UniProtKB: B5DFL3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240043   ⟸   XM_006239981
- Peptide Label: isoform X1
- UniProtKB: B5DFL3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000071708   ⟸   ENSRNOT00000092192
RefSeq Acc Id: XP_038967878   ⟸   XM_039111950
- Peptide Label: isoform X1
- UniProtKB: B5DFL3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967881   ⟸   XM_039111953
- Peptide Label: isoform X1
- UniProtKB: B5DFL3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967879   ⟸   XM_039111951
- Peptide Label: isoform X1
- UniProtKB: B5DFL3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967880   ⟸   XM_039111952
- Peptide Label: isoform X1
- UniProtKB: B5DFL3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000095877   ⟸   ENSRNOT00000103709
RefSeq Acc Id: ENSRNOP00000086750   ⟸   ENSRNOT00000116410
Protein Domains
PID

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B5DFL3-F1-model_v2 AlphaFold B5DFL3 1-200 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694515
Promoter ID:EPDNEW_R5037
Type:single initiation site
Name:Itgb1bp1_1
Description:integrin subunit beta 1 binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0643,363,324 - 43,363,384EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307810 AgrOrtholog
BioCyc Gene G2FUF-38041 BioCyc
Ensembl Genes ENSRNOG00000059402 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000071708 ENTREZGENE
  ENSRNOP00000071708.2 UniProtKB/TrEMBL
  ENSRNOP00000086750.1 UniProtKB/TrEMBL
  ENSRNOP00000095877 ENTREZGENE
  ENSRNOP00000095877.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000092192 ENTREZGENE
  ENSRNOT00000092192.2 UniProtKB/TrEMBL
  ENSRNOT00000103709 ENTREZGENE
  ENSRNOT00000103709.1 UniProtKB/TrEMBL
  ENSRNOT00000116410.1 UniProtKB/TrEMBL
InterPro Integrin_bd_ICAP-1 UniProtKB/TrEMBL
  PTyr_interaction_dom UniProtKB/TrEMBL
KEGG Report rno:298914 UniProtKB/TrEMBL
NCBI Gene 298914 ENTREZGENE
PANTHER PTHR32055 UniProtKB/TrEMBL
Pfam ICAP-1_inte_bdg UniProtKB/TrEMBL
PhenoGen Itgb1bp1 PhenoGen
SMART PTB UniProtKB/TrEMBL
UniProt A0A0G2K157_RAT UniProtKB/TrEMBL
  A0A8I6A2U6_RAT UniProtKB/TrEMBL
  B5DFL3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-23 Itgb1bp1  integrin subunit beta 1 binding protein 1  Itgb1bp1  integrin beta 1 binding protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Itgb1bp1  integrin beta 1 binding protein 1   Itgb1bp1_predicted  integrin beta 1 binding protein 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Itgb1bp1_predicted  integrin beta 1 binding protein 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED